Intraocular Pressure Increased, Narrow Anterior Chamber Angle, Myopia, Conjunctivitis (8491159-8)
on Jan 16, 2012 Female patient from UNITED STATES , 15 years of age, was diagnosed with

• migraine (migraine Questions)

and was treated with Topiramate(View Usage). Patient experienced the following unwanted or unexpected effects: intraocular pressure increased, narrow anterior chamber angle, myopia, conjunctivitis. Topiramate dosage: 1/day For 7 Days, 2/day Thereafter (25 Mg).

Pneumonia (8484869-X)
Patient was taking Topiramate (View Usage). Patient had the following side effects: pneumonia (pneumonia Questions) on May 15, 2012 from UNITED STATES Additional patient health information: Male patient , 19 years of age, . Topiramate dosage: N/A.
Patient was taking other medications:

• CLONAZEPAM (View Clonazepam Review and Clonazepam Label )
• GABATRIL (TIAGABINE HYDROCHLORIDE) (View Gabatril (tiagabine Hydrochloride) Review and Gabatril (tiagabine Hydrochloride) Label )
• LAMICTAL (View Lamictal Review and Lamictal Label )
• DIAZEPAM (View Diazepam Review and Diazepam Label )
• VIMPAT (View Vimpat Review and Vimpat Label )
• RUFINIMIDE (View Rufinimide Review and Rufinimide Label )
• FELBATOL (View Felbatol Review and Felbatol Label )
• SABRIL (1000 Mg Milligram(s), Am, Oral; 1250 Mg Milligram(s), Pm, Oral) (View Sabril Review and Sabril Label )

Patient was hospitalized.

Fatigue (8479611-2)
Adverse event was reported on Jun 27, 2012 by a Female patient taking Topiramate (View Usage) (Dosage: 50 Mg, 2x/day) was diagnosed with

• migraine (migraine Questions)
• contraception
• fibromyalgia
• depression (depression Questions)
• cardiac disorder
• hypothyroidism

and. Location: UNITED STATES , weighting 158.7 lb, After Topiramate was administered, patient had the following side effects: fatigue.
Patient was taking other medications:

• MEDROXYPROGESTERONE (10 Mg, 1x/day) (View Medroxyprogesterone Review and Medroxyprogesterone Label )
• LYRICA (75 Mg, 2x/day) (View Lyrica Review and Lyrica Label )
• CITALOPRAM (10 Mg, 1x/day) (View Citalopram Review and Citalopram Label )
• ISOSORBIDE (30 Mg, 2x/day) (View Isosorbide Review and Isosorbide Label )
• LEVOTHYROXINE (75 Ug, Unk) (View Levothyroxine Review and Levothyroxine Label )
• PLAVIX (75 Mg, 1x/day) (View Plavix Review and Plavix Label )
• LORAZEPAM (1 Mg, 2x/day) (View Lorazepam Review and Lorazepam Label )
• ASPIRIN (325 Mg, Unk) (View Aspirin Review and Aspirin Label )

Depression, Blister, Eye Swelling, Rash Macular (8478231-3)
on Jun 20, 2012 Male patient from FRANCE , 13 years of age, was diagnosed with

• epilepsy (epilepsy Questions)

and was treated with Topiramate (View Usage). Patient experienced the following unwanted or unexpected effects: depression (depression Questions), blister, eye swelling, rash macular. Topiramate dosage: 2 Weeks.


Abortion Induced, Oligohydramnios, Maternal Exposure During Pregnancy (8477196-8)
on Jun 15, 2012 Female patient from TURKEY , 32 years of age, was treated with Topiramate(View Usage). Patient had the following side effects: abortion induced, oligohydramnios, maternal exposure during pregnancy. Topiramate dosage: 100 Mg, Unk.
Patient was taking other medications:

• OXCARBAZEPINE (300 Mg, Unk) (View Oxcarbazepine Review and Oxcarbazepine Label )

Encephalopathy (8475925-0)
Patient was taking Topiramate (View Usage). After Topiramate was administered, patient had the following side effects: encephalopathy on Jun 18, 2012 from KOREA, REPUBLIC OF Additional patient health information: Male patient , 25 years of age, was diagnosed with

• epilepsy (epilepsy Questions)

and. Topiramate dosage: Unk.
Patient was taking other medications:

• VALPROATE SODIUM (2700 Mg, Daily) (View Valproate Sodium Review and Valproate Sodium Label )
• PHENOBARBITAL TAB (Unk) (View Phenobarbital Tab Review and Phenobarbital Tab Label )
• LEVETIRACETAM (Unk) (View Levetiracetam Review and Levetiracetam Label )
• PHENYTOIN (Unk) (View Phenytoin Review and Phenytoin Label )

Granulocytopenia (8473780-6)
Adverse event was reported on May 21, 2012 by a Female patient taking Topiramate (View Usage) (Dosage: N/A) . Location: UNITED STATES , 18 years of age, Patient experienced the following unwanted or unexpected effects: granulocytopenia.
Patient was taking other medications:

• CLOZAPINE (View Clozapine Review and Clozapine Label )

Tearfulness, Affect Lability, Slow Speech, Cognitive Disorder, Dysphemia (8470218-X)
on Jun 13, 2012 Female patient from UNITED KINGDOM , 54 years of age, weighting 152.0 lb, was treated with Topiramate (View Usage). Patient had the following side effects: tearfulness, affect lability, slow speech, cognitive disorder, dysphemia. Topiramate dosage: Unk.
Patient was taking other medications:

• SUMATRIPTAN (Unk) (View Sumatriptan Review and Sumatriptan Label )
• DEXAMETHASONE (Unk) (View Dexamethasone Review and Dexamethasone Label )

Pulmonary Embolism (8465375-5)
on Sep 22, 2011 Male patient from UNITED STATES , 70 years of age, was treated with Topiramate(View Usage). After Topiramate was administered, patient had the following side effects: pulmonary embolism (pulmonary embolism Questions). Topiramate dosage: N/A.
Patient was taking other medications:

• DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label )
• REVLIMID (10 Mg, Daily For 21 Days, Po) (View Revlimid Review and Revlimid Label )
• FLOMAX (View Flomax Review and Flomax Label )
• ZYRTEC ALLERGY (CETIRIZINE HYDROCHLORIDE) (View Zyrtec Allergy (cetirizine Hydrochloride) Review and Zyrtec Allergy (cetirizine Hydrochloride) Label )
• LOW DOSE ASPIRIN (ACETYLSALICYLIC ACID) (View Low Dose Aspirin (acetylsalicylic Acid) Review and Low Dose Aspirin (acetylsalicylic Acid) Label )
• POLYETHYLENE GLYCOL 600 (MACROGOL) (View Polyethylene Glycol 600 (macrogol) Review and Polyethylene Glycol 600 (macrogol) Label )
• LOVAZA (View Lovaza Review and Lovaza Label )
• MIRALAX (View Miralax Review and Miralax Label )

Amenorrhoea, Polycystic Ovaries, Therapeutic Response Unexpected, Blood Prolactin Increased (8464763-0)
Patient was taking Topiramate (View Usage). Patient experienced the following unwanted or unexpected effects: amenorrhoea, polycystic ovaries, therapeutic response unexpected, blood prolactin increased on Jun 14, 2012 from INDIA Additional patient health information: Female patient , 18 years of age, . Topiramate dosage: N/A.
Patient was taking other medications:

• TRIHEXYPHENIDYL HCL (View Trihexyphenidyl Hcl Review and Trihexyphenidyl Hcl Label )

Somnambulism (8461313-X)
Adverse event was reported on Jun 11, 2012 by a Female patient taking Topiramate (View Usage) (Dosage: 25 Mg, Daily) was diagnosed with

• prophylaxis

and. Location: INDIA , 35 years of age, Patient had the following side effects: somnambulism.

Somnambulism (8461267-6)
on Jun 11, 2012 Male patient from INDIA , 27 years of age, was treated with Topiramate (View Usage). After Topiramate was administered, patient had the following side effects: somnambulism. Topiramate dosage: Unk.

Renal Tubular Acidosis, Hallucination (8457853-X)
on Jun 11, 2012 Female patient from CHINA , 13 years of age, was treated with Topiramate(View Usage). Patient experienced the following unwanted or unexpected effects: renal tubular acidosis, hallucination. Topiramate dosage: N/A.

Hypersensitivity, Dysphemia, Tremor, Pain, Insomnia, Balance Disorder (8455073-6)
Patient was taking Topiramate (View Usage). Patient had the following side effects: hypersensitivity, dysphemia, tremor, pain (pain Questions), insomnia, balance disorder on Jun 15, 2012 from UNITED STATES Additional patient health information: Female patient , weighting 187.0 lb, was diagnosed with

• migraine (migraine Questions)

and. Topiramate dosage: 25 Mg X2 / Day.

Confusional State, Nervousness, Hypoaesthesia, Paraesthesia, Blood Urine Present, Restlessness, Bone Pain, Memory Impairment, Chest Pain (8454769-X)
Adverse event was reported on Jun 15, 2012 by a Female patient taking Topiramate (View Usage) (Dosage: 1 For 2 Wks - 2 To 3 Up Q 2wks Of Noc Po) was diagnosed with

• migraine (migraine Questions)

and. Location: UNITED STATES , 60 years of age, weighting 140.0 lb, After Topiramate was administered, patient had the following side effects: confusional state, nervousness, hypoaesthesia, paraesthesia, blood urine present, restlessness, bone pain, memory impairment, chest pain (chest pain Questions).

Convulsion (8454691-9)
on Jun 15, 2012 Female patient from UNITED STATES , weighting 39.02 lb, was diagnosed with

• epilepsy (epilepsy Questions)

and was treated with Topiramate (View Usage). Patient experienced the following unwanted or unexpected effects: convulsion. Topiramate dosage: 15mg In Am, 30mg In Pm Orally.

Affective Disorder, Product Substitution Issue, Convulsion, Abnormal Behaviour (8450104-1)
on Jun 14, 2012 Male patient from UNITED STATES , weighting 795.9 lb, was diagnosed with

• complex partial seizures

and was treated with Topiramate(View Usage). Patient had the following side effects: affective disorder, product substitution issue, convulsion, abnormal behaviour. Topiramate dosage: 100mg Bid; 50mg 1 Tab Am 1 1/2 Pm.

Foetal Exposure During Pregnancy, Premature Baby, Convulsion (8449881-5)
Patient was taking Topiramate (View Usage). After Topiramate was administered, patient had the following side effects: foetal exposure during pregnancy, premature baby, convulsion on Jun 08, 2012 from FRANCE Additional patient health information: Male patient , weighting 1.92 lb, was diagnosed with

• foetal exposure during pregnancy

and. Topiramate dosage: N/A.
Patient was taking other medications:

• NITRAZEPAM (View Nitrazepam Review and Nitrazepam Label )
• TEGRETOL (View Tegretol Review and Tegretol Label )
• KEPPRA (View Keppra Review and Keppra Label )

Patient was hospitalized.

Dyspnoea, Hypertensive Crisis, Increased Appetite, Dyspepsia, Anxiety, Mood Altered, Chromaturia, Back Pain, Dizziness (8439875-8)
Adverse event was reported on Jun 12, 2012 by a Female patient taking Topiramate (View Usage) (Dosage: 50 Mg, Qhs) was diagnosed with

• migraine (migraine Questions)

and. Location: UNITED STATES , weighting 250.0 lb, Patient experienced the following unwanted or unexpected effects: dyspnoea, hypertensive crisis, increased appetite, dyspepsia, anxiety (anxiety Questions), mood altered, chromaturia, back pain (back pain Questions), dizziness (dizziness Questions).
Patient was taking other medications:

• LISINOPRIL (10 Mg, Unk) (View Lisinopril Review and Lisinopril Label )
• CELEXA (20 Mg, Unk) (View Celexa Review and Celexa Label )
• GILENYA (0.5 Mg, Qd) (View Gilenya Review and Gilenya Label )
• PROPRANOLOL (40 Mg, Q6h) (View Propranolol Review and Propranolol Label )

Iridocyclitis, Angle Closure Glaucoma, Myopia, Cataract, Iris Adhesions (8439494-3)
on Jun 01, 2012 Female patient from IRAN (ISLAMIC REPUBLIC OF) , 40 years of age, was diagnosed with

• migraine (migraine Questions)

and was treated with Topiramate (View Usage). Patient had the following side effects: iridocyclitis, angle closure glaucoma, myopia, cataract (cataract Questions), iris adhesions. Topiramate dosage: 25 Mg, Tid. Patient was hospitalized.

Metamorphopsia (8438480-7)
on Jun 01, 2012 Female patient from BRAZIL , 33 years of age, was treated with Topiramate(View Usage). After Topiramate was administered, patient had the following side effects: metamorphopsia. Topiramate dosage: 100 Mg/day.

Fanconi Syndrome, Hypophosphataemic Rickets, Nephrocalcinosis (8438336-X)
Patient was taking Topiramate (View Usage). Patient experienced the following unwanted or unexpected effects: fanconi syndrome, hypophosphataemic rickets, nephrocalcinosis on Jun 14, 2012 from CANADA Additional patient health information: Female patient , child 10 years of age, weighting 25.13 lb, was diagnosed with

• convulsion

and. Topiramate dosage: 25 Mg A.m, 12.5 Mg P.m, 25 Mg Nocte.
Patient was taking other medications:

• VALPROIC ACID (125 Md A.m, 62.5 Mg P.m, 125 Mg Nocte) (View Valproic Acid Review and Valproic Acid Label )
• LANSOPRAZOLE (View Lansoprazole Review and Lansoprazole Label )
• CALCIUM CARBONATE (View Calcium Carbonate Review and Calcium Carbonate Label )
• L CARNITINE (View L-carnitine Review and L-carnitine Label )

Nausea (8437119-4)
Adverse event was reported on Apr 02, 2012 by a Female patient taking Topiramate (View Usage) (Dosage: Unk) . Location: UNITED STATES , 55 years of age, Patient had the following side effects: nausea (nausea Questions).
Patient was taking other medications:

• TREXIMET (Unk) (View Treximet Review and Treximet Label )
• PROLIA (60 Mg, Q6mo) (View Prolia Review and Prolia Label )
• VAGIFEM (Unk) (View Vagifem Review and Vagifem Label )

Visual Impairment, Urinary Tract Disorder, Disturbance In Attention, Dizziness, Depression, Psychomotor Skills Impaired, Nausea, Vocal Cord Disorder (8435656-X)
on Jun 06, 2012 Male patient from FRANCE , 58 years of age, was treated with Topiramate (View Usage). After Topiramate was administered, patient had the following side effects: visual impairment, urinary tract disorder, disturbance in attention, dizziness (dizziness Questions), depression (depression Questions), psychomotor skills impaired, nausea (nausea Questions), vocal cord disorder. Topiramate dosage: N/A.

Completed Suicide (8433265-X)
on Jun 13, 2012 Female patient from UNITED STATES , 44 years of age, was treated with Topiramate(View Usage). Patient experienced the following unwanted or unexpected effects: completed suicide. Topiramate dosage: N/A.
Patient was taking other medications:

• VERAPAMIL HCL (View Verapamil Hcl Review and Verapamil Hcl Label )
• IMIPRAMINE (View Imipramine Review and Imipramine Label )