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Trazadol Side Effects

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Common Trazadol Side Effects


The most commonly reported Trazadol side effects (click to view or check a box to report):

Arthralgia (2)
Crying (2)
Fibromyalgia (2)
Depression (2)
Hypokinesia (2)
Somnolence (2)
Muscular Weakness (2)
Pain In Extremity (1)
Loss Of Consciousness (1)
Activities Of Daily Living Impaired (1)
Gait Disturbance (1)


If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Trazadol Side Effects Reported to FDA


Trazadol Side Effect Report#7518243-7
Hypokinesia, Depression, Muscular Weakness, Arthralgia, Crying, Fibromyalgia, Somnolence, Activities Of Daily Living Impaired, Pain In Extremity
This is a report of a female patient (weight: NA) from United States, suffering from the following health symptoms/conditions: sleep disorder, who was treated with Trazadol (dosage: Unk, start time:
Nov 01, 2010), combined with:
  • Calcium Carbonate (Unk)
  • Fentanyl (Unk)
  • Alprazolam (Unk, Q8h)
  • Dilaudid (Unk)
  • Hydrocodone Bitartrate (Unk)
  • Leuprolide Acetate (11.25 Mg, Every 3 Months)
  • Prenatal Vitamins /01549301/ (Unk)
and developed a serious reaction and side effect(s): Hypokinesia, Depression, Muscular Weakness, Arthralgia, Crying, Fibromyalgia, Somnolence, Activities Of Daily Living Impaired, Pain In Extremity after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Trazadol treatment in female patients, resulting in Hypokinesia side effect. The patient was hospitalized.
Trazadol Side Effect Report#7479357-3
Gait Disturbance, Loss Of Consciousness, Somnolence, Depression, Muscular Weakness, Crying, Fibromyalgia, Hypokinesia, Arthralgia
This report suggests a potential Trazadol Gait Disturbance side effect(s) that can have serious consequences. A female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: sleep disorder and used Trazadol (dosage: Unk) starting
Feb 01, 2011. After starting Trazadol the patient began experiencing various side effects, including: Gait Disturbance, Loss Of Consciousness, Somnolence, Depression, Muscular Weakness, Crying, Fibromyalgia, Hypokinesia, ArthralgiaAdditional drugs used concurrently:
  • Calcium (Unk)
  • Alprazolam (Unk, Q8h)
  • Prenatal Vitamins /01549301/ (Unk)
  • Leuprolide Acetate (11.25 Mg, Every 3 Months)
  • Dilaudid (Unk)
  • Hydrocodone Bitartrate (Unk)
  • Fentanyl (Unk)
The patient was hospitalized. Although Trazadol demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Gait Disturbance, may still occur.



The appearance of Trazadol on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


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Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Trazadol reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    More About Trazadol

    Side Effects reported to FDA: 2

    Trazadol safety alerts: No

    Reported hospitalizations: 2

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