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Extreme Fatigue (25)
Feeling Dazed (12)
CHEST PAIN (11)
Headache (8)
Cough (7)
Feeling Dazed And Extreme Fatigue (6)
Low BP (5)
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Trimetazidine Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Hallucination, Visual, Aggression, Hypothyroidism (8120418-3)
on Jan 18, 2012 Male from FRANCE , 78 years of age, was treated with Trimetazidine Hydrochloride. Directly after, patient experienced the unwanted or unexpected Trimetazidine side effects: hallucination, visual, aggression, hypothyroidism. Trimetazidine Hydrochloride dosage: 35 Mg, 2x/day.
Associated medications used:
  • Potassium Chloride (600 Mg, 1x/day)
  • Esomeprazole (40 Mg, 1x/day)
  • Nootropyl (800 Mg, 3x/day)
  • Altace (1.25 Mg, 2x/day)
  • Lasix (20 Mg, 2x/day)
  • Cordarone (200 Mg, Unk)
  • Avodart (Unk)
  • Travatan (Unk)
Patient was hospitalized.

Injection Site Haematoma (8077912-3)
Patient was taking Trimetazidine. Patient felt the following Trimetazidine side effects: injection site haematoma on Jan 05, 2011 from UNITED STATES Additional patient health information: Female , 34 years of age, . Trimetazidine dosage: N/A.
Multiple prescriptions taken:
  • Humira
  • Lorazepam
  • Elmiron
  • Ambien
  • Neurontin
  • Vicodin
  • Nexium
  • Risperdal


Leukaemia (8065661-7)
Adverse event was reported on Jan 05, 2012 by a Male taking Trimetazidine (trimetazidine) (trimetazidine) (Dosage: N/A) . Location: BRAZIL , 65 years of age, After Trimetazidine was administered, patient encountered several Trimetazidine side effects: leukaemia.
Multiple concurrent drugs taken:
  • Acetylsalicylic Acid Srt
  • Levothyroxine Sodium
  • Warfarin Sodium
  • Nilotinib (nilotinib) (nilotinib)
  • Benicar Hct (40/12.5 Mg (1 In 1 D),per Oral ; 20/12.5 Mg (1 In 1 D),per Oral)
  • Benicar Hct (40/12.5 Mg (1 In 1 D),per Oral ; 20/12.5 Mg (1 In 1 D),per Oral)
  • Amiodarone Hcl
  • Atorvastatin (atorvastatin) (atorvastatin)
Patient was hospitalized.

Shock (7926893-9)
on Nov 15, 2011 Female from POLAND , 75 years of age, weighting 154.3 lb, was treated with Trimetazidine. Directly after, patient experienced the unwanted or unexpected Trimetazidine side effects: shock. Trimetazidine dosage: N/A.
Associated medications used:
  • Siofor
  • Sunitinib Malate (37.5 Mg, 1x/day, Daily 4/2)
  • Effox Long
  • Diabrezide
  • Molsidomina
  • Vitamin B Complex Cap
Patient was hospitalized.


Blood Pressure Abnormal, Headache, Gastrointestinal Carcinoma, Overdose (7811037-4)
on Sep 27, 2011 Male from BRAZIL , 80 years of age, was treated with Trimetazidine. Patient felt the following Trimetazidine side effects: blood pressure abnormal, headache, gastrointestinal carcinoma, overdose. Trimetazidine dosage: N/A.
Multiple prescriptions taken:
  • Benicar (120/15 Mg (1 D), Per Oral : 160/20 Mg (1 D), Per Oral : 40/5 Mg (1 In 1 D), Per Oral)
  • Benicar (120/15 Mg (1 D), Per Oral : 160/20 Mg (1 D), Per Oral : 40/5 Mg (1 In 1 D), Per Oral)
  • Benicar (120/15 Mg (1 D), Per Oral : 160/20 Mg (1 D), Per Oral : 40/5 Mg (1 In 1 D), Per Oral)
  • Diltiazem Hcl


Blood Pressure Abnormal, Headache, Gastrointestinal Carcinoma, Overdose (7811037-4)
Patient was taking Trimetazidine. After Trimetazidine was administered, patient encountered several Trimetazidine side effects: blood pressure abnormal, headache, gastrointestinal carcinoma, overdose on Sep 27, 2011 from BRAZIL Additional patient health information: Male , 80 years of age, . Trimetazidine dosage: N/A.
Multiple concurrent drugs taken:
  • Amlodipine Besylate And Olmesartan Medoxomil (120/15 Mg (1 D), Per Oral : 160/20 Mg (1 D), Per Oral : 40/5 Mg (1 In 1 D), Per Oral)
  • Amlodipine Besylate And Olmesartan Medoxomil (120/15 Mg (1 D), Per Oral : 160/20 Mg (1 D), Per Oral : 40/5 Mg (1 In 1 D), Per Oral)
  • Amlodipine Besylate And Olmesartan Medoxomil (120/15 Mg (1 D), Per Oral : 160/20 Mg (1 D), Per Oral : 40/5 Mg (1 In 1 D), Per Oral)
  • Diltiazem Hcl


Rhabdomyolysis, Chest Pain, Hemiparesis, Multi-organ Failure, Cerebral Infarction, Respiratory Failure, Dysarthria (7776058-9)
Adverse event was reported on Sep 15, 2011 by a Male taking Trimetazidine (Dosage: N/A) . Location: CHINA , 60 years of age, Directly after, patient experienced the unwanted or unexpected Trimetazidine side effects: rhabdomyolysis, chest pain, hemiparesis, multi-organ failure, cerebral infarction, respiratory failure, dysarthria.
Associated medications used:
  • Tcms
  • Crestor
  • Amlodipine
  • Aspirin
  • Clopidogrel
Patient was hospitalized.

Gastrointestinal Haemorrhage (7775288-X)
on Sep 23, 2011 Female from PHILIPPINES , 73 years of age, was treated with Trimetazidine. Patient felt the following Trimetazidine side effects: gastrointestinal haemorrhage. Trimetazidine dosage: N/A.
Multiple prescriptions taken:
  • Beta-blocker
  • Pradaxa (220 Mg)
  • Lanoxin


Hemiparesis, Multi-organ Failure, Chest Pain, Dysarthria, Rhabdomyolysis, Respiratory Failure, Cerebral Infarction (7727640-6)
on Aug 29, 2011 Male from CHINA , 60 years of age, was treated with Trimetazidine. After Trimetazidine was administered, patient encountered several Trimetazidine side effects: hemiparesis, multi-organ failure, chest pain, dysarthria, rhabdomyolysis, respiratory failure, cerebral infarction. Trimetazidine dosage: N/A.
Multiple concurrent drugs taken:
  • Tcms
  • Clopidogrel
  • Amlodipine
  • Crestor
  • Aspirin
Patient was hospitalized.

Acute Myocardial Infarction (7704127-8)
Patient was taking Trimetazidine Hydrochloride. Directly after, patient experienced the unwanted or unexpected Trimetazidine side effects: acute myocardial infarction on Aug 17, 2011 from JAPAN Additional patient health information: Female , 72 years of age, . Trimetazidine Hydrochloride dosage: Unk.
Associated medications used:
  • Ferrous Sulfate Tab (Unk)
  • Rebamipide (Unk)
  • Omega 3 /00931501/ (Unk)
  • Cinacalcet Hydrochloride (Unk)
  • Simvastatin (Unk)
  • Vitamin B/c Complex (Unk Unk, Unk)
  • Vitamin B/c Complex (Uncertainty)
  • Vitamin B/c Complex (Uncertainty)
Patient was hospitalized.

Fall, Vertigo (7681192-8)
Adverse event was reported on Aug 01, 2011 by a Female taking Trimetazidine Hydrochloride (Dosage: N/A) . Location: FRANCE , 89 years of age, Patient felt the following Trimetazidine side effects: fall, vertigo.
Multiple prescriptions taken:
  • Tramadol Hcl
  • Seretide Diskus
  • Trimebutine
  • Isosorbide Dinitrate
  • Nitroderm
  • Acetaminophen
  • Lasix
  • Escitalopram Oxalate
Patient was hospitalized.

(7586997-X)
on Jun 17, 2011 Female from MOROCCO , 80 years of age, weighting 211.6 lb, was treated with Trimetazidine. . Trimetazidine dosage: Unk.
Multiple concurrent drugs taken:
  • Valsartan And Hydrochlorothiazide (160/12.5 Mg, Unk)
  • Simvastatin (Unk)
  • Aspirin (Unk)
  • Insuline (Unk)
  • Digoxin (Unk)


Prostate Cancer Metastatic (7540904-4)
on Jun 07, 2011 Male from TUNISIA , 83 years of age, was treated with Trimetazidine Hydrochloride. Directly after, patient experienced the unwanted or unexpected Trimetazidine side effects: prostate cancer metastatic. Trimetazidine Hydrochloride dosage: N/A.
Associated medications used:
  • Lasix
  • Atorvastatin
  • Aspirin
  • Nitroglycerin
  • Plavix
  • Aspirin
  • Corvasal
  • Omeprazole


Gastrooesophageal Reflux Disease, Cough, Dyspepsia (7504686-4)
Patient was taking Trimetazidine Hydrochloride. Patient felt the following Trimetazidine side effects: gastrooesophageal reflux disease, cough, dyspepsia on May 24, 2011 from GREECE Additional patient health information: Patient , 70 years of age, weighting 169.8 lb, . Trimetazidine Hydrochloride dosage: N/A.
Multiple prescriptions taken:
  • Amlodipine Besylate
  • Amlodipine Besylate
  • Gliclazide
  • Janumet
  • Ticlopidine Hydrochloride
  • Simvastatin


Acute Respiratory Failure, Bronchopneumopathy (7464223-X)
Adverse event was reported on May 02, 2011 by a Female taking Trimetazidine Biogaran (Dosage: N/A) . Location: FRANCE , 72 years of age, After Trimetazidine was administered, patient encountered several Trimetazidine side effects: acute respiratory failure, bronchopneumopathy.
Multiple concurrent drugs taken:
  • Actonel
  • Chondrosulf
  • Bisoprolol Fumarate And Hydrochlorothiazide
  • Arava
  • Ketoprofen
  • Nexium
  • Fenofibrate
  • Buspirone Hcl
Patient was hospitalized.

Dysphonia, Enlarged Uvula, Hypertrophy, Laryngeal Oedema (5169380-6)
on Nov 21, 2006 Male from FRANCE , 85 years of age, was treated with Trimetazidine (ngx) (trimetazidine). Directly after, patient experienced the unwanted or unexpected Trimetazidine side effects: dysphonia, enlarged uvula, hypertrophy, laryngeal oedema. Trimetazidine (ngx) (trimetazidine) dosage: Oral.
Associated medications used:
  • Bisoprolol Gnr (ngx) (bisoprolol) (Oral)
Patient was hospitalized.

Trimetazidine Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Trimetazidine Information

More About Trimetazidine

Side Effects reported to FDA: 16. View Trimetazidine Adverse Reports

Trimetazidine safety alerts: No

Reported deaths: 3

Reported hospitalizations: 3

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