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1.5 million people annually are harmed from drug errors.
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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Valproate Safety Reports submitted to FDA

Total Valproate reports: 129.
Valproate FDA safety alerts: 2002 2008 .
Reported deaths: 35    Reported hospitalizations: 58.
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FDA Reported Valproate Side Effects: convulsion, status epilepticus, hepatotoxicity, coma, electroencephalogram abnormal, thrombocytopenia, hepatic failure, confusional state, hepatic function abnormal, hyponatraemia, hepatic cirrhosis.
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Showing 1-100 of 129 Next >

Valproate Side Effects Report #5186543-4
Consumer or non-health professional from FRANCE reported VALPROATE problem on Dec 12, 2006. Male patient, child 8 years of age, was diagnosed with electroencephalogram abnormal, epilepsy and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: cerebral atrophy, mental impairment. VALPROATE dosage: unknown. During the same period patient was treated with CLOBAZAM. Patient recovered.

Valproate Side Effects Report #5195018-8
VALPROATE problem was reported by a Health Professional from FRANCE on Dec 21, 2006. Male patient, 72 years of age, was diagnosed with pain and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: feeling abnormal. VALPROATE dosage: unknown. During the same period patient was treated with TRAMADOL, ASPIRIN, ENALAPRIL MALEATE, OMEPRAZOLE. Patient recovered.

Valproate Side Effects Report #5195019-X
Consumer or non-health professional from INDIA reported VALPROATE problem on Dec 20, 2006. Male patient, child 2 years of age, was diagnosed with febrile convulsion and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. VALPROATE dosage: unknown. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5388568-2
VALPROATE problem was reported by a Health Professional from AUSTRALIA on July 04, 2007. Female patient was diagnosed with sleep disorder, accidental overdose and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: abnormal sleep-related event, accidental overdose, amnesia, road traffic accident. VALPROATE dosage: unknown. During the same period patient was treated with ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, CITALOPRAM HYDROBROMIDE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5392686-2
Health Professional from FRANCE reported VALPROATE problem on July 11, 2007. Female patient, weighting 57.32 lb, was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: astigmatism, body dysmorphic disorder, cheilitis, congenital eye disorder, coordination abnormal, croup infectious, disturbance in attention, dysmorphism. VALPROATE dosage: unknown. During the same period patient was treated with CARBAMAZEPINE. Patient recovered.

Valproate Side Effects Report #5392691-6
VALPROATE problem was reported by a Health Professional from FRANCE on July 11, 2007. Female patient, weighting 5.86 lb, was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, asthma, developmental delay, dysmorphism, educational problem, expressive language disorder, eye disorder, foetal anticonvulsant syndrome, foot deformity. VALPROATE dosage: unknown. Patient recovered.

Valproate Side Effects Report #5397990-X
Health Professional from AUSTRALIA reported VALPROATE problem on July 16, 2007. Female patient, weighting 154.3 lb, was diagnosed with affective disorder, sleep disorder, accidental overdose and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: abnormal sleep-related event, accidental overdose, amnesia, road traffic accident. VALPROATE dosage: unknown. During the same period patient was treated with CITALOPRAM HYDROBROMIDE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5399670-3
VALPROATE problem was reported by a Health Professional from FRANCE on July 19, 2007. Female patient, 41 years of age, was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: intentional overdose, suicide attempt. VALPROATE dosage: unknown. During the same period patient was treated with VENLAFAXIINE, OLANZAPINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5405382-X
Physician from FRANCE reported VALPROATE problem on July 26, 2007. Male patient, 34 years of age, was diagnosed with depression, affective disorder and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: convulsion. VALPROATE dosage: unknown. During the same period patient was treated with DOSULEPIN. Patient recovered.

Valproate Side Effects Report #5405590-8
VALPROATE problem was reported by a Physician from FRANCE on July 26, 2007. Male patient, child 8 years of age, was diagnosed with convulsion, intracranial pressure increased, medulloblastoma and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: brain neoplasm, dyskinesia, muscle contractions involuntary, thrombocytopenia. VALPROATE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ACETAZOLAMIDE, VINCRISTINE, ETOPOSIDE, CARBOPLATIN. Patient recovered.

Valproate Side Effects Report #5410166-2
Physician from FRANCE reported VALPROATE problem on Aug 02, 2007. Male patient, 34 years of age, was diagnosed with depression, affective disorder and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: convulsion. VALPROATE dosage: unknown. During the same period patient was treated with DOSULEPIN. Patient recovered.

Valproate Side Effects Report #5410958-X
VALPROATE problem was reported by a Consumer or non-health professional from FRANCE on Aug 01, 2007. Male patient, 16 years of age, was diagnosed with epilepsy, autism, abnormal behaviour, sleep disorder and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: oedema peripheral. VALPROATE dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, RISPERIDONE, MELATONIN. Patient recovered.

Valproate Side Effects Report #5415458-9
Consumer or non-health professional from CANADA reported VALPROATE problem on July 23, 2007. Female patient, 58 years of age, was diagnosed with bipolar disorder and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: convulsion, neck pain. VALPROATE dosage: 500 MG;BID; 500 MG;TAB;PO;BID; 1500 MG;TAB;PO;QD; 1000 MG;TAB;PO;QD. During the same period patient was treated with TEMAZEPAM, TRAZODONE, HYDROMORPHONE, LOSARTAN POTASSIUM, PROCYCLIDINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5418134-1
VALPROATE problem was reported by a Consumer or non-health professional from TURKEY on Aug 07, 2007. Female patient, weighting 9.92 lb, was diagnosed with convulsion and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: brain oedema, hyperammonaemia, overdose. VALPROATE dosage: unknown. Patient died.

Valproate Side Effects Report #5430149-6
Consumer or non-health professional from ITALY reported VALPROATE problem on Aug 16, 2007. Female patient, child 9. years of age, was diagnosed with convulsion, pneumonia and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: convulsion. VALPROATE dosage: 20 MG/KG/DAY. During the same period patient was treated with MEROPENEM. Patient recovered.

Valproate Side Effects Report #5441760-0
VALPROATE problem was reported by a Health Professional from SINGAPORE on Aug 31, 2007. Male patient, 34 years of age, was diagnosed with schizophrenia and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain, abdominal tenderness, blood creatinine increased, blood pressure decreased, blood urea increased, colectomy, constipation, dehydration. VALPROATE dosage: 400 MG, TID. During the same period patient was treated with BENZTROPINE MESYLATE, DIAZEPAM, CLOZAPINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445793-X
Consumer or non-health professional from BELGIUM reported VALPROATE problem on Aug 28, 2007. Male patient, 16 years of age, was diagnosed with status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENYTOIN, PHENOBARBITAL, CLOBAZAM, TOPIRAMATE, LAMOTRIGINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445794-1
VALPROATE problem was reported by a Consumer or non-health professional from BELGIUM on Aug 28, 2007. Male patient, 15 years of age, was diagnosed with partial seizures, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, LORAZEPAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445795-3
Consumer or non-health professional from BELGIUM reported VALPROATE problem on Aug 28, 2007. Male patient, 57 years of age, was diagnosed with status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENYTOIN. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445796-5
VALPROATE problem was reported by a Consumer or non-health professional from BELGIUM on Aug 28, 2007. Female patient, 23 years of age, was diagnosed with partial seizures, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENYTOIN, LEVETIRACETAM, MIDAZOLAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445797-7
Consumer or non-health professional from BELGIUM reported VALPROATE problem on Aug 28, 2007. Female patient, 71 years of age, was diagnosed with myoclonic epilepsy, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENOBARBITAL, TOPIRAMATE, PROPOFOL, MIDAZOLAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445798-9
VALPROATE problem was reported by a Consumer or non-health professional from BELGIUM on Aug 28, 2007. Female patient, 43 years of age, was diagnosed with status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENYTOIN, PHENOBARBITAL. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445799-0
Consumer or non-health professional from BELGIUM reported VALPROATE problem on Aug 28, 2007. Female patient, 41 years of age, was diagnosed with status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENOBARBITAL, PHENYTOIN, PROPOFOL, MIDAZOLAM, LEVETIRACETAM, TOPIRAMATE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445800-4
VALPROATE problem was reported by a Consumer or non-health professional from BELGIUM on Aug 28, 2007. Male patient, 46 years of age, was diagnosed with grand mal convulsion, status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENOBARBITAL. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445801-6
Consumer or non-health professional from BELGIUM reported VALPROATE problem on Aug 28, 2007. Male patient, 74 years of age, was diagnosed with status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, CARBAMAZEPINE, LEVETIRACETAM, TOPIRAMATE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445802-8
VALPROATE problem was reported by a Consumer or non-health professional from BELGIUM on Aug 28, 2007. Male patient, 43 years of age, was diagnosed with status epilepticus, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENOBARBITAL, TOPIRAMATE, LEVETIRACETAM, MIDAZOLAM, PROPOFOL. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5445805-3
Consumer or non-health professional from BELGIUM reported VALPROATE problem on Aug 28, 2007. Male patient, 71 years of age, was diagnosed with status epilepticus, simple partial seizures, infection and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: electroencephalogram abnormal. VALPROATE dosage: unknown. During the same period patient was treated with MEROPENEM, PHENYTOIN, PHENOBARBITAL. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5453290-0
VALPROATE problem was reported by a Consumer or non-health professional from FRANCE on Sept 06, 2007. Male patient, weighting 8.82 lb, was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: amblyopia, autism spectrum disorder, congenital nose malformation, congenital oral malformation, dysmorphism, foetal anticonvulsant syndrome, head deformity, strabismus. VALPROATE dosage: unknown. During the same period patient was treated with FOLATE. Patient recovered.

Valproate Side Effects Report #5470235-8
Physician from FRANCE reported VALPROATE problem on Sept 18, 2007. Male patient, child 8 years of age, was diagnosed with convulsion, intracranial pressure increased, medulloblastoma and was treated with VALPROATE. After drug was administered, patient experienced the following problems/side effects: dyskinesia, muscle contractions involuntary, thrombocytopenia. VALPROATE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ACETAZOLAMIDE, VINCRISTINE, ETOPOSIDE, CARBOPLATIN. Patient recovered.

Showing 1-100 of 129 Next >


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cerebral atrophy, mental impairment feeling abnormal thrombocytopenia abnormal sleep-related event, accidental overdose, amnesia, road traffic accident, was diagnosed with electroencephalogram abnormal, epilepsy and was diagnosed with pain and was diagnosed with febrile convulsion and