Common Venlafaxiine Side Effects


The most commonly reported Venlafaxiine side effects (click to view or check a box to report):

Rhabdomyolysis (3)
Condition Aggravated (3)
Overdose (3)
Serotonin Syndrome (3)
Convulsion (3)
Dizziness (3)
Agitation (2)
Atrial Fibrillation (2)
Disturbance In Attention (2)
Heart Rate Increased (2)
Headache (2)
Blood Pressure Increased (2)
Paraesthesia (2)
Intentional Overdose (2)
Hyperhidrosis (2)
Loss Of Consciousness (2)
Malaise (2)
Pulmonary Oedema (2)
Insulin C-peptide Increased (1)
Infection (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Venlafaxiine Side Effects Reported to FDA



Venlafaxiine Side Effect Report#5763784-6
Delirium, Infection, Mental Status Changes, Serotonin Syndrome
This is a report of a 53-year-old female patient (weight: NA) from United States, suffering from the following health symptoms/conditions: depression, who was treated with Venlafaxiine Hcl (dosage: 75 Mg, Qd, start time: NS), combined with:
  • Fluoxetine (40 Mg, Qd)
  • Methadone Hcl (50 Mg, Qd)
  • Olanzapine
  • Bupropion Hcl
and developed a serious reaction and side effect(s): Delirium, Infection, Mental Status Changes, Serotonin Syndrome after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in female patients, resulting in Delirium side effect. The patient was hospitalized.
Venlafaxiine Side Effect Report#5761929-5
Blood Pressure Increased, Convulsion, Heart Rate Increased, Hyperhidrosis, Hyperreflexia, Mydriasis, Pupillary Reflex Impaired
This report suggests a potential Venlafaxiine Hcl Blood Pressure Increased side effect(s) that can have serious consequences. A 36-year-old female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: depression,headache,bipolar disorder,empyema and used Venlafaxiine Hcl (dosage: NA) starting NS. After starting Venlafaxiine Hcl the patient began experiencing various side effects, including: Blood Pressure Increased, Convulsion, Heart Rate Increased, Hyperhidrosis, Hyperreflexia, Mydriasis, Pupillary Reflex ImpairedAdditional drugs used concurrently:
  • Imipramine
  • Lithium Carbonate
  • Linezolid
  • Vancomycin
The patient was hospitalized. Although Venlafaxiine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Pressure Increased, may still occur.
Venlafaxiine Side Effect Report#5739735-7
Aggression, Agitation, Alcohol Use, Amnesia, Conversion Disorder, Impulsive Behaviour, Incorrect Dose Administered, Loss Of Consciousness, Obsessive Thoughts
This Aggression problem was reported by a health professional from United States. A 41-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 15, 2008 this consumer started treatment with Venlafaxiine Hcl (dosage: 75 Mg 2 Pd Po). The following drugs were being taken at the same time: NA. When using Venlafaxiine Hcl, the patient experienced the following unwanted symptoms/side effects: Aggression, Agitation, Alcohol Use, Amnesia, Conversion Disorder, Impulsive Behaviour, Incorrect Dose Administered, Loss Of Consciousness, Obsessive ThoughtsThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Aggression, may become evident only after a product is in use by the general population.
Venlafaxiine Side Effect Report#5717323-6
Abnormal Dreams, Affect Lability, Anxiety, Disturbance In Attention, Dizziness, Headache, Night Sweats, Paraesthesia
This Abnormal Dreams side effect was reported by a consumer or non-health professional from United States. A 45-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Venlafaxiine Hcl (drug dosage: 75 Mg Once Nightly Po), which was initiated on
Apr 14, 2008. Concurrently used drugs:
  • Sudafed Otc
  • Zyrtec Otc
.After starting to take Venlafaxiine Hcl the consumer reported adverse symptoms, such as: Abnormal Dreams, Affect Lability, Anxiety, Disturbance In Attention, Dizziness, Headache, Night Sweats, ParaesthesiaThese side effects may potentially be related to Venlafaxiine Hcl.
Venlafaxiine Side Effect Report#5532926-X
Abdominal Rigidity, Muscle Spasms
This is a report of a 13-year-old patient (weight: NA) from United Kingdom, suffering from the following health symptoms/conditions: depression, who was treated with Venlafaxiine Hcl (dosage: NA, start time:
Aug 30, 2007), combined with: NA. and developed a serious reaction and side effect(s): Abdominal Rigidity, Muscle Spasms after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in patients, resulting in Abdominal Rigidity side effect.
Venlafaxiine Side Effect Report#5530780-3
Appetite Disorder, Balance Disorder, Depressed Mood, Diarrhoea, Disturbance In Attention, Dizziness, Fatigue, Feeling Abnormal
This report suggests a potential Venlafaxiine Hcl Appetite Disorder side effect(s) that can have serious consequences. A female patient (weight: NA) from United Kingdom was diagnosed with the following symptoms/conditions: major depression,anxiety and used Venlafaxiine Hcl (dosage: 37.5mg A.m, 75mg P.m) starting
Jun 14, 2005. After starting Venlafaxiine Hcl the patient began experiencing various side effects, including: Appetite Disorder, Balance Disorder, Depressed Mood, Diarrhoea, Disturbance In Attention, Dizziness, Fatigue, Feeling AbnormalAdditional drugs used concurrently: NA. Although Venlafaxiine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Appetite Disorder, may still occur.
Venlafaxiine Side Effect Report#5527529-7
Disorientation, Heart Rate Increased, Heart Rate Irregular, Somnolence
This Disorientation problem was reported by a health professional from United Kingdom. A 48-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: hot flush,prophylaxis,hypertension. On
Oct 19, 2007 this consumer started treatment with Venlafaxiine Hcl (dosage: NA). The following drugs were being taken at the same time:
  • Atorvastatin Calcium
  • Losartan Potassium
  • Aspirin
When using Venlafaxiine Hcl, the patient experienced the following unwanted symptoms/side effects: Disorientation, Heart Rate Increased, Heart Rate Irregular, SomnolenceAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Disorientation, may become evident only after a product is in use by the general population.
Venlafaxiine Side Effect Report#5521142-3
This Sudden Infant Death Syndrome side effect was reported by a health professional from United Kingdom. A female patient (weight:NA) experienced the following symptoms/conditions: schizophrenia,sleep disorder.The patient was prescribed Venlafaxiine Hcl (drug dosage: NA), which was initiated on
Sep 11, 2007. Concurrently used drugs:
  • Zopiclone
  • Quetiapine Fumarate
.After starting to take Venlafaxiine Hcl the consumer reported adverse symptoms, such as: These side effects may potentially be related to Venlafaxiine Hcl.
Venlafaxiine Side Effect Report#5519115-X
This is a report of a 56-year-old female patient (weight: NA) from United Kingdom, suffering from the following health symptoms/conditions: depression, who was treated with Venlafaxiine Hcl (dosage: NA, start time:
Aug 01, 2004), combined with:
  • Aspirin
  • Co-tenidone
  • Simvastatin
  • Lercanidipine
  • Perindopril
  • Premarin
  • Propranolol
  • Amitriptyline Hcl
and developed a serious reaction and side effect(s): after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in female patients, resulting in Sudden Cardiac Death side effect.
Venlafaxiine Side Effect Report#5508337-X
Compartment Syndrome, Condition Aggravated, Rhabdomyolysis
This report suggests a potential Venlafaxiine Hcl Compartment Syndrome side effect(s) that can have serious consequences. A 25-year-old male patient (weight: NA) from Brazil was diagnosed with the following symptoms/conditions: depression,agitation and used Venlafaxiine Hcl (dosage: NA) starting NS. After starting Venlafaxiine Hcl the patient began experiencing various side effects, including: Compartment Syndrome, Condition Aggravated, RhabdomyolysisAdditional drugs used concurrently:
  • Haloperidol
The patient was hospitalized. Although Venlafaxiine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Compartment Syndrome, may still occur.
Venlafaxiine Side Effect Report#5505961-5
Arrhythmia
This Arrhythmia problem was reported by a health professional from United Kingdom. A 84-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Jun 01, 2006 this consumer started treatment with Venlafaxiine Hcl (dosage: NA). The following drugs were being taken at the same time:
  • Calcichew-d3
  • Clonazepam
  • Co-codamol
  • Digoxin
  • Zolpidem Tartrate
  • Movicol
  • Omeprazole
  • Quetiapine Fumarate
When using Venlafaxiine Hcl, the patient experienced the following unwanted symptoms/side effects: ArrhythmiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Arrhythmia, may become evident only after a product is in use by the general population.
Venlafaxiine Side Effect Report#5504900-0
Overdose, Ventricular Extrasystoles, Ventricular Tachycardia
This Overdose side effect was reported by a physician from United Kingdom. A 55-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Venlafaxiine Hcl (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Paroxetine Hcl
.After starting to take Venlafaxiine Hcl the consumer reported adverse symptoms, such as: Overdose, Ventricular Extrasystoles, Ventricular TachycardiaThese side effects may potentially be related to Venlafaxiine Hcl. The patient was hospitalized.
Venlafaxiine Side Effect Report#5504899-7
Overdose, Supraventricular Tachycardia
This is a report of a 36-year-old female patient (weight: NA) from United Kingdom, suffering from the following health symptoms/conditions: NA, who was treated with Venlafaxiine Hcl (dosage: 3 G (overdose Amount), start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Overdose, Supraventricular Tachycardia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in female patients, resulting in Overdose side effect. The patient was hospitalized.
Venlafaxiine Side Effect Report#5504898-5
Atrial Fibrillation, Overdose
This report suggests a potential Venlafaxiine Hcl Atrial Fibrillation side effect(s) that can have serious consequences. A 30-year-old female patient (weight: NA) from United Kingdom was diagnosed with the following symptoms/conditions: NA and used Venlafaxiine Hcl (dosage: 3.25 G (overdose Amount)) starting NS. After starting Venlafaxiine Hcl the patient began experiencing various side effects, including: Atrial Fibrillation, OverdoseAdditional drugs used concurrently:
  • Ibuprofen (3.2 G (overdose Amount))
The patient was hospitalized. Although Venlafaxiine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Atrial Fibrillation, may still occur.
Venlafaxiine Side Effect Report#5486985-3
Headache, Hypertension, Phaeochromocytoma, Photophobia
This Headache problem was reported by a pharmacist from United Kingdom. A 36-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On NS this consumer started treatment with Venlafaxiine Hcl (dosage: NA). The following drugs were being taken at the same time:
  • Effexor Xr
When using Venlafaxiine Hcl, the patient experienced the following unwanted symptoms/side effects: Headache, Hypertension, Phaeochromocytoma, PhotophobiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Venlafaxiine Side Effect Report#5443028-5
Paraesthesia, Tremor
This Paraesthesia side effect was reported by a health professional from United Kingdom. A 50-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression,personality disorder,extrapyramidal disorder.The patient was prescribed Venlafaxiine Hcl (drug dosage: NA), which was initiated on
May 01, 2007. Concurrently used drugs: NA..After starting to take Venlafaxiine Hcl the consumer reported adverse symptoms, such as: Paraesthesia, TremorThese side effects may potentially be related to Venlafaxiine Hcl.
Venlafaxiine Side Effect Report#5442977-1
Chills, Condition Aggravated, Panic Attack, Pyrexia
This is a report of a 33-year-old male patient (weight: NA) from United Kingdom, suffering from the following health symptoms/conditions: depression,anxiety, who was treated with Venlafaxiine Hcl (dosage: NA, start time:
Jan 01, 2006), combined with:
  • Dosulepin (75mg, Frequency Not Stated)
and developed a serious reaction and side effect(s): Chills, Condition Aggravated, Panic Attack, Pyrexia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in male patients, resulting in Chills side effect.
Venlafaxiine Side Effect Report#5442122-2
Anaemia, Blood Iron Decreased, Cardiotoxicity, Catabolic State, Cerebral Haemorrhage, Clostridium Difficile Colitis, Dehydration, Encephalopathy, Hepatic Failure
This report suggests a potential Venlafaxiine Hcl Anaemia side effect(s) that can have serious consequences. A 36-year-old female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: convulsion and used Venlafaxiine Hcl (dosage: NA) starting NS. After starting Venlafaxiine Hcl the patient began experiencing various side effects, including: Anaemia, Blood Iron Decreased, Cardiotoxicity, Catabolic State, Cerebral Haemorrhage, Clostridium Difficile Colitis, Dehydration, Encephalopathy, Hepatic FailureAdditional drugs used concurrently:
  • Metoclopramide
  • Neurontin
  • Depakote
  • Dilantin Kapseal
  • Klonopin
  • Tegretol
  • Keppra
  • Mysoline
The patient was hospitalized. Although Venlafaxiine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaemia, may still occur.
Venlafaxiine Side Effect Report#5429859-6
Agitation, Blood Insulin Increased, Blood Pressure Increased, Clonus, Depressed Level Of Consciousness, Eye Movement Disorder, Gastric Lavage, Hypoglycaemia, Insulin C-peptide Increased
This Agitation problem was reported by a physician from Netherlands. A 29-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: incorrect dose administered. On NS this consumer started treatment with Venlafaxiine Hcl (dosage: 22.5 G, Single Dose). The following drugs were being taken at the same time:
  • Oxazepam (5 G, Single Dose)
When using Venlafaxiine Hcl, the patient experienced the following unwanted symptoms/side effects: Agitation, Blood Insulin Increased, Blood Pressure Increased, Clonus, Depressed Level Of Consciousness, Eye Movement Disorder, Gastric Lavage, Hypoglycaemia, Insulin C-peptide IncreasedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Agitation, may become evident only after a product is in use by the general population.
Venlafaxiine Side Effect Report#5428989-2
Disinhibition, Homicidal Ideation, Homicide
This Disinhibition side effect was reported by a physician from United Kingdom. A 36-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Venlafaxiine Hcl (drug dosage: NA), which was initiated on
Jan 01, 2006. Concurrently used drugs: NA..After starting to take Venlafaxiine Hcl the consumer reported adverse symptoms, such as: Disinhibition, Homicidal Ideation, HomicideThese side effects may potentially be related to Venlafaxiine Hcl.
Venlafaxiine Side Effect Report#5377306-5
Blood Creatine Phosphokinase Increased, Condition Aggravated, Electrocardiogram Qrs Complex Prolonged, Electrocardiogram Qt Prolonged, Grand Mal Convulsion, Hypoxia, Intentional Overdose, Intentional Self-injury, Loss Of Consciousness
This is a report of a 21-year-old female patient (weight: NA) from United Kingdom, suffering from the following health symptoms/conditions: NA, who was treated with Venlafaxiine Hcl (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Blood Creatine Phosphokinase Increased, Condition Aggravated, Electrocardiogram Qrs Complex Prolonged, Electrocardiogram Qt Prolonged, Grand Mal Convulsion, Hypoxia, Intentional Overdose, Intentional Self-injury, Loss Of Consciousness after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in female patients, resulting in Blood Creatine Phosphokinase Increased side effect. The patient was hospitalized.
Venlafaxiine Side Effect Report#5360753-5
Dizziness, Feeling Hot, Hyperhidrosis, Increased Tendency To Bruise, Liver Function Test Abnormal, Malaise, Menorrhagia
This report suggests a potential Venlafaxiine Hcl Dizziness side effect(s) that can have serious consequences. A female patient (weight: NA) from United Kingdom was diagnosed with the following symptoms/conditions: anxiety and used Venlafaxiine Hcl (dosage: NA) starting
Jan 24, 2006. After starting Venlafaxiine Hcl the patient began experiencing various side effects, including: Dizziness, Feeling Hot, Hyperhidrosis, Increased Tendency To Bruise, Liver Function Test Abnormal, Malaise, MenorrhagiaAdditional drugs used concurrently: NA. Although Venlafaxiine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dizziness, may still occur.
Venlafaxiine Side Effect Report#5357105-0
Respiratory Depression
This Respiratory Depression problem was reported by a health professional from Ireland. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Mar 01, 2006 this consumer started treatment with Venlafaxiine Hcl (dosage: NA). The following drugs were being taken at the same time:
  • Corticosteroid Nos
When using Venlafaxiine Hcl, the patient experienced the following unwanted symptoms/side effects: Respiratory DepressionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Respiratory Depression, may become evident only after a product is in use by the general population.
Venlafaxiine Side Effect Report#5320435-2
Lower Respiratory Tract Infection, Malaise, Myalgia, Pleurisy, Pneumonia
This Death side effect was reported by a health professional from United Kingdom. A 31-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression,asthma.The patient was prescribed Venlafaxiine Hcl (drug dosage: NA), which was initiated on
Mar 29, 2006. Concurrently used drugs:
  • Salbutamol
  • Beclomethasone Dipropionate
  • Dihydrocodeine Bitartrate Inj
  • Clozaril
  • Ranitidine
.After starting to take Venlafaxiine Hcl the consumer reported adverse symptoms, such as: Lower Respiratory Tract Infection, Malaise, Myalgia, Pleurisy, PneumoniaThese side effects may potentially be related to Venlafaxiine Hcl.
Venlafaxiine Side Effect Report#5317520-8
Acute Left Ventricular Failure, Convulsion, Intentional Overdose, Pulmonary Oedema, Respiratory Failure, Rhabdomyolysis, Serotonin Syndrome, Suicide Attempt
This is a report of a 30-year-old female patient (weight: NA) from France, suffering from the following health symptoms/conditions: NA, who was treated with Venlafaxiine Hcl (dosage: Overdose Amount Was 5.5 G, start time: NS), combined with:
  • Alprazolam (Overdose Amount Was 500 Mg)
  • Hydroxyzine (Overdose Amount Was 250 Mg)
and developed a serious reaction and side effect(s): Acute Left Ventricular Failure, Convulsion, Intentional Overdose, Pulmonary Oedema, Respiratory Failure, Rhabdomyolysis, Serotonin Syndrome, Suicide Attempt after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Venlafaxiine Hcl treatment in female patients, resulting in Acute Left Ventricular Failure side effect. The patient was hospitalized.


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The appearance of Venlafaxiine on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Venlafaxiine Side Effects for Women?

Women Side Effects Reports
Convulsion 3
Dizziness 3
Serotonin Syndrome 3
Atrial Fibrillation 2
Disturbance In Attention 2
Heart Rate Increased 2
Hyperhidrosis 2
Intentional Overdose 2
Loss Of Consciousness 2
Overdose 2

What are common Venlafaxiine Side Effects for Men?

Men Side Effects Reports
Condition Aggravated 2
Agitation 1
Blood Insulin Increased 1
Blood Pressure Increased 1
Chills 1
Clonus 1
Compartment Syndrome 1
Death 1
Depressed Level Of Consciousness 1
Disinhibition 1

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    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Venlafaxiine reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    More About Venlafaxiine

    Side Effects reported to FDA: 28

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    Reported deaths: 5

    Reported hospitalizations: 13

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