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side effects patient, 47 years of age, weighting 249.1 lb, was diagnosed with pain and took Vitamin k . View more Serious Adverse Events reported to FDA.

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List of Vitamin K Adverse Effects reported to US Food and Drug Administration (FDA)

Showing 1-25 of 54 

Swelling, International Normalised Ratio Increased, Haematoma, Rash, Contusion, Diarrhoea (7604852-3)
on Jul 05, 2011 Male patient from UNITED STATES , 47 years of age, weighting 249.1 lb, was treated with Vitamin K Tab. Patient experienced the following unwanted or unexpected effects: swelling, international normalised ratio increased, haematoma, rash, contusion, diarrhoea. Vitamin K Tab dosage: N/A.
Patient also using the following medications:
  • Darbepoetin Alfa
  • Granisetron (1 Mg, Unk)
  • Oxycodone Hcl (5 Mg, Unk)
  • Dexamethasone (20 Mg, Unk)
  • Erlotinib Hydrochloride (150 Mg, Unk)
  • Warfarin Sodium (2.5 Mg, Unk)
  • Alprazolam (0.5 Mg, Unk)
  • Bevacizumab (1497 Mg, Unk)


International Normalised Ratio Increased, Diarrhoea, Contusion, Haematoma, Rash, Swelling (7583809-5)
Patient was taking Vitamin K Tab. Patient had the following side effects: international normalised ratio increased, diarrhoea, contusion, haematoma, rash, swelling on Jun 24, 2011 from UNITED KINGDOM Additional patient health information: Male patient , 47 years of age, . Vitamin K Tab dosage: N/A.
Patient also using the following medications:
  • Loperamide
  • Citalopram Hydrobromide
  • Oxycodone Hcl
  • Carboplatin
  • Cimetidine
  • Darbepoetin Alfa
  • Paclitaxel
  • Bevacizumab


Hypotension, Platelet Count Decreased, Hypocalcaemia, Mucosal Inflammation, Hypokalaemia, Dehydration, Hyperbilirubinaemia, Anaemia (7580703-0)
Adverse event was reported on Jun 17, 2011 by a Male patient taking Vitamin K Tab (Dosage: N/A) was diagnosed with
  • coagulopathy
and. Location: UNITED STATES , weighting 169.8 lb, After Vitamin K was administered, patient had the following side effects: hypotension, platelet count decreased, hypocalcaemia, mucosal inflammation, hypokalaemia, dehydration, hyperbilirubinaemia, anaemia.
Patient also using the following medications:
  • Carboplatin (3 Df, Other)
  • Folic Acid
  • Avodart (5 Mg, Daily (1/d))
  • Pemetrexed (250 Mg/m2, Other)
  • Carboplatin (6 D/f, Other)
  • Emend
  • Flomax (0.4 Mg, Daily (1/d))
  • Vitamin B-12
Patient was hospitalized.

Dyspnoea, Haemorrhage Intracranial (7523382-0)
on May 24, 2011 Male patient from CHINA , 38 years of age, weighting 134.5 lb, was treated with Vitamin K Antagonist. Patient experienced the following unwanted or unexpected effects: dyspnoea, haemorrhage intracranial. Vitamin K Antagonist dosage: N/A.
Patient also using the following medications:
  • Arixtra (2.5mg Per Day)



Paraesthesia, Feeling Abnormal (7469521-1)
on May 02, 2011 Female patient from FRANCE , 67 years of age, weighting 198.4 lb, was treated with Vitamin K Tab. Patient had the following side effects: paraesthesia, feeling abnormal. Vitamin K Tab dosage: N/A.
Patient also using the following medications:
  • Multaq
Patient was hospitalized.

Deep Vein Thrombosis, Fatigue, Pulmonary Embolism, Oedema Peripheral (7464788-8)
Patient was taking Vitamin K Tab. After Vitamin K was administered, patient had the following side effects: deep vein thrombosis, fatigue, pulmonary embolism, oedema peripheral on Apr 08, 2011 from UNITED STATES Additional patient health information: Female patient , 40 years of age, weighting 250.0 lb, . Vitamin K Tab dosage: N/A.
Patient also using the following medications:
  • Yaz (Unk)
  • Yasmin (Unk)
Patient was hospitalized.

Antepartum Haemorrhage (7431225-9)
Adverse event was reported on Apr 14, 2011 by a Female patient taking Vitamin K Tab (Dosage: N/A) was diagnosed with
  • vitamin supplementation
  • in vitro fertilisation
and. Location: UNITED STATES , weighting 157.1 lb, Patient experienced the following unwanted or unexpected effects: antepartum haemorrhage.
Patient also using the following medications:
  • Inositol
  • Lovenox
  • Dexamethasone
  • Resveratrol
  • Gonal-e
  • Vitamin D
  • Vitamin D
  • Immune Globulin Intravenous (human)


Liver Disorder (7414663-X)
on Aug 18, 2008 Female patient from FRANCE , 82 years of age, was diagnosed with
  • thrombosis prophylaxis
  • multiple myeloma
and was treated with Vitamin K Antagonist. Patient had the following side effects: liver disorder. Vitamin K Antagonist dosage: N/A.
Patient also using the following medications:
  • Thalidomide (100)
  • Thalidomide (50)


Thrombocytopenia, Fracture, Blood Creatinine Increased, Leukopenia, Parkinson's Disease (7400272-5)
on Mar 28, 2011 Male patient from TAIWAN, PROVINCE OF CHINA , 63 years of age, weighting 128.7 lb, was diagnosed with
  • anaemia
and was treated with Vitamin K1. After Vitamin K was administered, patient had the following side effects: thrombocytopenia, fracture, blood creatinine increased, leukopenia, parkinson's disease. Vitamin K1 dosage: 1 Df, Monthly (1/m).
Patient also using the following medications:
  • Bisacodyl (5 Mg, Qd)
  • Biperiden Hydrochloride Tab (2 Mg, Tid)
  • Trazodone Hcl (50 Mg, Qd)
  • Estazolam (2 Mg, Qd)
  • Risperidone (2 Mg, Qd)
  • Olanzapine (5 Mg, Qd)
  • Haloperidol (1.25 Mg, Bid)
  • Biperiden Hydrochloride Tab (2 Mg, Tid)
Patient was hospitalized.

Torsade De Pointes, Atrial Fibrillation, Tachyarrhythmia (7395519-8)
Patient was taking Vitamin K /01542801/. Patient experienced the following unwanted or unexpected effects: torsade de pointes, atrial fibrillation, tachyarrhythmia on Mar 17, 2011 from GERMANY Additional patient health information: Female patient , 50 years of age, . Vitamin K /01542801/ dosage: N/A.
Patient also using the following medications:
  • Plasma
  • Red Blood Cells, Concentrated
  • Erythromycin ((before Esophagogastroduodenoscopy Intravenous)), (10 Hours Later Intravenous)))
  • Pantoprazole
  • Amiodarone (amiodarone) ((300 Mg Intravenous)))
  • Ciprofloxacin ((df))
  • Insulin
  • Hemopressin


Monoplegia (7387322-X)
Adverse event was reported on Mar 22, 2011 by a Male patient taking Vitamin K Tab (Dosage: Several Times) . Location: GERMANY , 66 years of age, weighting 132.3 lb, Patient had the following side effects: monoplegia.
Patient also using the following medications:
  • Aerius
  • Erbitux
  • Euthyrox
  • Sucralfate (3-4daily)
  • Polyethylene Glycol (Mouth Wash)
  • Daktarin (Daktarin Gel 2percent,1df=2-3ml,2-3daily)
Patient was hospitalized.

Multi-organ Failure, Rash, Septic Shock, Skin Necrosis, Oedema, Renal Failure Acute, Cardiopulmonary Failure, Skin Exfoliation, Pulse Absent (7364597-4)
on Mar 16, 2011 Female patient from BRAZIL , 74 years of age, was treated with Vitamin K Tab. After Vitamin K was administered, patient had the following side effects: multi-organ failure, rash, septic shock, skin necrosis, oedema, renal failure acute, cardiopulmonary failure, skin exfoliation, pulse absent. Vitamin K Tab dosage: N/A.
Patient also using the following medications:
  • Warfarin Sodium (15 Mg, Unk)
  • Heparin
  • Warfarin Sodium (10 Mg, Unk)
  • Warfarin Sodium (5 Mg, Unk)
Patient was hospitalized.

Neutropenia, White Blood Cell Count Decreased (7305009-6)
on Feb 17, 2011 Female patient from IRELAND , 30 years of age, was treated with Vitamin K Tab. Patient experienced the following unwanted or unexpected effects: neutropenia, white blood cell count decreased. Vitamin K Tab dosage: 10 Mg, Unk.
Patient also using the following medications:
  • Prednisolone (55 Mg, Unk)
  • Calcichew-d3 (Unk)
  • Aldactone (25 Mg, Unk)
  • Pantoprazole (40 Mg, Unk)
Patient was hospitalized.

Nausea, Vomiting, Peritoneal Haemorrhage, Blood Pressure Decreased, Abdominal Pain Upper, White Blood Cell Count Increased, Ovarian Cyst, Intra-abdominal Haemorrhage, Localised Intraabdominal Fluid Collection (7282042-4)
Patient was taking Vitamin K Tab. Patient had the following side effects: nausea, vomiting, peritoneal haemorrhage, blood pressure decreased, abdominal pain upper, white blood cell count increased, ovarian cyst, intra-abdominal haemorrhage, localised intraabdominal fluid collection on Jan 21, 2011 from TURKEY Additional patient health information: Female patient , 44 years of age, . Vitamin K Tab dosage: N/A.
Patient also using the following medications:
  • Warfarin Sodium (5 Mg, Qd)
  • Enoxaparin Sodium
  • Fresh Frozen Plasma
Patient was hospitalized.

Peritoneal Haemorrhage, Nausea, White Blood Cell Count Increased, Localised Intraabdominal Fluid Collection, Abdominal Tenderness, Blood Pressure Decreased, Abdominal Pain Upper, Ovarian Cyst, Intra-abdominal Haemorrhage (7274561-1)
Adverse event was reported on Jan 21, 2011 by a Female patient taking Vitamin K Tab (Dosage: N/A) . Location: TURKEY , 44 years of age, After Vitamin K was administered, patient had the following side effects: peritoneal haemorrhage, nausea, white blood cell count increased, localised intraabdominal fluid collection, abdominal tenderness, blood pressure decreased, abdominal pain upper, ovarian cyst, intra-abdominal haemorrhage.
Patient also using the following medications:
  • Warfarin (5 Mg, Qd)
  • Fresh Frozen Plasma
  • Enoxaparin Sodium
Patient was hospitalized.

Angioedema, Cardiac Arrest (7228194-3)
on Jan 12, 2011 Male patient from UNITED STATES , 63 years of age, weighting 286.0 lb, was treated with Vitamin K Tab. Patient experienced the following unwanted or unexpected effects: angioedema, cardiac arrest. Vitamin K Tab dosage: N/A.

Dyspnoea, Eye Swelling, Infusion Related Reaction, Lacrimation Increased (6587757-9)
on Feb 17, 2010 Female patient from UNITED STATES , 76 years of age, weighting 125.7 lb, was diagnosed with
  • international normalised ratio abnormal
and was treated with Vitamin K Injection 10mg/ml Hospira. Patient had the following side effects: dyspnoea, eye swelling, infusion related reaction, lacrimation increased. Vitamin K Injection 10mg/ml Hospira dosage: 10mg Once Iv Drip.

Flushing, Unresponsive To Stimuli (6538754-0)
Patient was taking Vitamin K1. After Vitamin K was administered, patient had the following side effects: flushing, unresponsive to stimuli on Jan 14, 2010 from UNITED STATES Additional patient health information: Female patient , 83 years of age, weighting 141.1 lb, was diagnosed with
  • international normalised ratio increased
and. Vitamin K1 dosage: 10 Mg One Time Iv.

Angioedema, Respiratory Failure (6298098-1)
Adverse event was reported on Aug 04, 2009 by a Male patient taking Vitamin K 10mg/ml (Dosage: N/A) was diagnosed with
  • international normalised ratio increased
and. Location: UNITED STATES , weighting 280.0 lb, Patient experienced the following unwanted or unexpected effects: angioedema, respiratory failure.

Cyanosis, Jaundice (6086162-1)
on Feb 17, 2009 Male patient from UNITED STATES , weighting 7.50 lb, was diagnosed with
  • vitamin supplementation
and was treated with Vitamin K1. Patient had the following side effects: cyanosis, jaundice. Vitamin K1 dosage: Give 1ml=25mcg Daily Po.

Anaphylactic Reaction, Loss Of Consciousness (6022387-9)
on Dec 23, 2008 Male patient from UNITED STATES , 49 years of age, weighting 172.6 lb, was diagnosed with
  • international normalised ratio increased
and was treated with Vitamin K. After Vitamin K was administered, patient had the following side effects: anaphylactic reaction, loss of consciousness. Vitamin K dosage: 10 Mg Once Iv Bolus. Patient was hospitalized.

Convulsion Neonatal, Haemorrhage Intracranial (5942996-2)
Patient was taking Vitamin K1. Patient experienced the following unwanted or unexpected effects: convulsion neonatal, haemorrhage intracranial on Oct 30, 2008 from UNITED STATES Additional patient health information: Male patient , weighting 5.95 lb, . Vitamin K1 dosage: 1 Mg, Once, Intramuscular.

Convulsion Neonatal, Haemorrhage Intracranial (5942939-1)
Adverse event was reported on Oct 30, 2008 by a Male patient taking Vitamin K1 (Dosage: 1 Mg, Once, Intramuscular) . Location: UNITED STATES , weighting 8.38 lb, Patient had the following side effects: convulsion neonatal, haemorrhage intracranial.

Abdominal Pain, Agitation, Back Pain, Blood Pressure Increased, Chest Pain, Chills, Flushing, Hypoaesthesia, Nausea (5918303-8)
on Oct 03, 2008 Male patient from UNITED STATES , 73 years of age, weighting 210.0 lb, was diagnosed with
  • international normalised ratio increased
  • abdominal pain
and was treated with Vitamin K1 Injection, 10mg/ml, 1ml Ampule (vitamin K1 Injection) (phyt. After Vitamin K was administered, patient had the following side effects: abdominal pain, agitation, back pain, blood pressure increased, chest pain, chills, flushing, hypoaesthesia, nausea. Vitamin K1 Injection, 10mg/ml, 1ml Ampule (vitamin K1 Injection) (phyt dosage: 5 Mg, Once Intravenous Bolus.
Patient also using the following medications:
  • Morphine Sulfate 1mg/ml Inj. Preserv. Free, Usp, 30 Ml Pca Abboject (m (0.5 Mg, Once, Intravenous Bolus)


Abdominal Pain, Agitation, Back Pain, Blood Pressure Increased, Chest Pain, Chills, Flushing, Hypoaesthesia, Nausea (5913564-3)
on Sep 29, 2008 Male patient from UNITED STATES , 73 years of age, weighting 210.0 lb, was diagnosed with
  • international normalised ratio increased
  • abdominal pain
and was treated with Vitamin K1. Patient experienced the following unwanted or unexpected effects: abdominal pain, agitation, back pain, blood pressure increased, chest pain, chills, flushing, hypoaesthesia, nausea. Vitamin K1 dosage: 5 Mg, Once, Intravenous Bolus.
Patient also using the following medications:
  • Morphine Sulfate (0.5 Mg, Once, Intravenous Bolus)


Showing 1-25 of 54 

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Vitamin K Information

Alternative VITAMIN K Names:PHYTONADI

Substance:PHYTONADI

More About Vitamin k

Side Effects reported to FDA: 54. View FDA Adverse Reports

Vitamin K safety alerts: No

Reported deaths: 10

Reported hospitalizations: 23

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Vitamin K Adverse Reactions

Neutropenia ( 6 Reports)

Pneumonia ( 6 Reports)

Appetite Disorder ( 5 Reports)

Cyanosis ( 5 Reports)

Duodenal Ulcer ( 5 Reports)

Dyspnoea ( 5 Reports)

Febrile Neutropenia ( 5 Reports)

Gastrointestinal Ulcer ( 5 Reports)

Nausea ( 5 Reports)

Hepatic Failure ( 4 Reports)

Hypotension ( 4 Reports)

Infusion Related Reaction ( 4 Reports)

Blood Pressure Decreased ( 3 Reports)

Contusion ( 3 Reports)

Deep Vein Thrombosis ( 3 Reports)

Fatigue ( 3 Reports)

Flushing ( 3 Reports)

Haemorrhage Intracranial ( 3 Reports)

International Normalised Ratio Increased ( 3 Reports)

Lethargy ( 3 Reports)

Peripheral Vascular Disorder ( 3 Reports)

Pulmonary Embolism ( 3 Reports)

Rash ( 3 Reports)

Renal Failure Acute ( 3 Reports)

Tonic Convulsion ( 3 Reports)

Vomiting ( 3 Reports)

Abdominal Pain ( 2 Reports)

Abdominal Pain Upper ( 2 Reports)

Agitation ( 2 Reports)

Angioedema ( 2 Reports)

side effects
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