Vorinostat Side Effects summary

Total Vorinostat reports: 16. View

Vorinostat FDA safety alerts: No.

Reported deaths: 1

Reported hospitalizations: 11.

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Recently reported Vorinostat Side Effects


Common Vorinostat Side Effects
Asthenia 19%
Vomiting 19%
Bundle branch block right 13%
Fall  What is  Fall                                                                                                                                                                                                    13%
Febrile neutropenia 13%
Nausea  What is  Nausea                                                                                                                                                                                                  13%
Neuropathy peripheral 13%
Oral intake reduced 13%
Pleural effusion 13%
Syncope 13%
Abdominal pain  What is  Abdominal pain                                                                                                                                                                                          6%
Activities of daily living impaired 6%
Amnesia 6%
Ascites 6%
B-cell lymphoma 6%
Body temperature increased 6%
Bone metabolism disorder 6%
Caecitis 6%
Cellulitis  What is  Cellulitis                                                                                                                                                                                              6%
Cheilitis 6%
Condition aggravated 6%
Dehydration 6%
Diabetes mellitus inadequate control 6%
Diabetic ketoacidosis 6%
Disorientation 6%
Dysuria 6%
Electrocardiogram qt prolonged 6%
Epstein-barr virus associated lymphoproliferative disorder 6%
Fatigue 6%
Haemoglobin decreased 6%
Hepatic enzyme increased 6%
Herpes simplex  What is  Herpes simplex                                                                                                                                                                                          6%
Hypercalcaemia 6%
Hypokalaemia 6%
Hypophagia 6%
Loss of consciousness 6%
Malignant neoplasm progression 6%
Muscle spasms 6%
Muscular weakness 6%
Mycosis fungoides 6%
Neuralgia 6%
No therapeutic response 6%
Obstruction gastric 6%
Oral disorder 6%
Pericardial effusion 6%
Pneumonia fungal 6%
Pyrexia 6%
Rash  What is  Rash                                                                                                                                                                                                    6%
Renal failure 6%
Somnolence 6%
Speech disorder 6%
Stenotrophomonas infection 6%
Syncope vasovagal 6%
Thrombocytopenia 6%
Treatment noncompliance 6%
Tremor 6%
Urinary tract obstruction 6%
Weight decreased 6%

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Vorinostat Side Effects Report #5369959-2
Health Professional from SINGAPORE reported Vorinostat side effect on June 12, 2007. Female patient, 51 years of age, was diagnosed with breast cancer metastatic and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: ascites, body temperature increased, dehydration, fatigue, hypokalaemia, obstruction gastric, oral intake reduced, pleural effusion, vomiting. Vorinostat dosage: 400 MG/AM/PO. During the same period patient was treated with METOCLOPRAMIDE, MORPHINE, POTASSIUM CHLORIDE, CHLORIDE, TOLBUTAMIDE. Patient was hospitalized. Patient died on 05/05/2007.



Vorinostat Side Effects Report #5378067-6
Vorinostat side effect was reported by a Physician from UNITED STATES on June 22, 2007. Male patient, 55 years of age, weighting 231.0 lb, was diagnosed with multiple myeloma What is  multiple myeloma and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: activities of daily living impaired, neuropathy peripheral. Vorinostat dosage: 400 MG/DAILY/PO. During the same period patient was treated with VELCADE, CENTRUM, FOSAMAX, VALTREX, VITAMIN B CAP. Patient recovered.



Vorinostat Side Effects Report #5378068-8
Physician from UNITED STATES reported Vorinostat side effect on June 22, 2007. Male patient, 67 years of age, weighting 92.00 lb, was diagnosed with multiple myeloma What is  multiple myeloma and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: amnesia, speech disorder, tremor. Vorinostat dosage: 400 MG/DAILY/PO. During the same period patient was treated with VELCADE, ACCUPRIL, ADVAIR DISKUS, CARDIZEM, CENTRUM, COUMADIN, LORTAB, LOVENOX. Patient recovered.



Vorinostat Side Effects Report #5483698-9
Vorinostat side effect was reported by a Health Professional from UNITED STATES on Sept 26, 2007. Female patient, 18 years of age, weighting 114.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, caecitis, cellulitis What is  cellulitis, cheilitis, febrile neutropenia, herpes simplex What is  herpes simplex, oral intake reduced, pyrexia, weight decreased. Vorinostat dosage: 400 MG/DAILY/PO CAP. During the same period patient was treated with DECITABINE. Patient was hospitalized. Patient recovered.




Vorinostat Side Effects Report #5505226-1
Health Professional from UNITED STATES reported Vorinostat side effect on Oct 18, 2007. Male patient, 73 years of age, weighting 209.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: febrile neutropenia. Vorinostat dosage: 400 MG/DAILY/PO. During the same period patient was treated with DECITABINE UNK. Patient was hospitalized. Patient recovered.



Vorinostat Side Effects Report #5591072-X
Vorinostat side effect was reported by a Pharmacist from UNITED STATES on Jan 11, 2008. Male patient, 55 years of age, was diagnosed with mycosis fungoides and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: diabetic ketoacidosis. Vorinostat dosage: 400MG DAILY PO. Patient was hospitalized. Patient recovered.



Vorinostat Side Effects Report #5621663-9
Health Professional from UNITED STATES reported Vorinostat side effect on Jan 22, 2008. Male patient, 56 years of age, weighting 150.0 lb, was diagnosed with non-small cell lung cancer, anxiety What is  anxiety and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: asthenia, diabetes mellitus inadequate control, disorientation, dysuria, fall What is  fall, loss of consciousness, malignant neoplasm progression, muscle spasms, muscular weakness. Vorinostat dosage: 200 MG/BID/PO. During the same period patient was treated with ERLOTINIB HYDROCHLORIDE, ATIVAN, ALTACE, CENTRUM SILVER, EXCEDRIN, LOMOTIL, ZYRTEC. Patient was hospitalized and became disabled. Patient recovered.



Vorinostat Side Effects Report #5684222-8
Vorinostat side effect was reported by a Pharmacist from UNITED STATES on Mar 27, 2008. Male patient, weighting 154.3 lb, was diagnosed with t-cell lymphoma and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: neuralgia, somnolence. Vorinostat dosage: 300MG QDAY PO. During the same period patient was treated with BORTEZOMIB. Patient was hospitalized. Patient recovered.



Vorinostat Side Effects Report #5744666-2
Physician from UNITED STATES reported Vorinostat side effect on Apr 30, 2008. Female patient, 71 years of age, weighting 152.0 lb, was diagnosed with acute myeloid leukaemia, rosacea What is  rosacea, hyperlipidaemia, acute leukaemia, myelodysplastic syndrome, hypertension, antibiotic prophylaxis and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: asthenia, bundle branch block right, electrocardiogram qt prolonged, nausea What is  nausea, oral disorder, syncope, treatment noncompliance. Vorinostat dosage: 400 MG/DAILY/PO. During the same period patient was treated with DOXYCYCLINE, GEMFIBROZIL, DECITABINE, BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE, AVELOX. Patient was hospitalized. Patient recovered.




Vorinostat Side Effects Report #5809587-5
Vorinostat side effect was reported by a Physician from GERMANY on June 12, 2008. Female patient, 48 years of age, was diagnosed with mycosis fungoides and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: bone metabolism disorder, condition aggravated, hypercalcaemia, mycosis fungoides, renal failure, thrombocytopenia. Vorinostat dosage: 400 MG/DAILY PO. Patient was hospitalized and became disabled. Patient recovered.



Vorinostat Side Effects Report #5869283-5
Physician from UNITED STATES reported Vorinostat side effect on Aug 15, 2008. Female patient, 71 years of age, weighting 152.0 lb, was diagnosed with acute myeloid leukaemia, myelodysplastic syndrome, rosacea What is  rosacea, hyperlipidaemia and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: asthenia, bundle branch block right, hypophagia, nausea What is  nausea, syncope, syncope vasovagal, urinary tract obstruction. Vorinostat dosage: 400 MG/DAILY/PO. During the same period patient was treated with DOXYCYCLINE, GEMFIBROZIL, DECITABINE. Patient was hospitalized. Patient recovered.



Vorinostat Side Effects Report #5957496-3
Vorinostat side effect was reported by a Physician from UNITED STATES on Nov 05, 2008. Male patient, 61 years of age, weighting 235.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: no therapeutic response, pneumonia fungal, stenotrophomonas infection. Vorinostat dosage: 400 MG/DAILY/PO. During the same period patient was treated with VICODIN, ZOFRAN, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.



Vorinostat Side Effects Report #5997295-X
Physician from UNITED STATES reported Vorinostat side effect on Nov 24, 2008. Female patient, 54 years of age, weighting 101.0 lb, was diagnosed with myelodysplastic syndrome and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: fall What is  fall, haemoglobin decreased, neuropathy peripheral. Vorinostat dosage: 200 MG/TID/PO. During the same period patient was treated with BENADRYL, COMPAZINE, ACETAMINOPHEN, CEPHALEXIN, MAGNESIA. Patient recovered.



Vorinostat Side Effects Report #5998017-9
Vorinostat side effect was reported by a Health Professional from UNITED STATES on Nov 28, 2008. Male patient, 71 years of age, weighting 116.0 lb, was diagnosed with myelodysplastic syndrome and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: pericardial effusion, pleural effusion. Vorinostat dosage: 200 MG/TID/PO. During the same period patient was treated with ACTOS, GLUCOTROL, CYANOCOBALAMIN, VITAMIN E, VITAMINS. Patient was hospitalized. Patient recovered.




Vorinostat Side Effects Report #6091462-5
Physician from UNITED STATES reported Vorinostat side effect on Feb 19, 2009. Male patient, 13 years of age, weighting 103.6 lb, was diagnosed with hodgkin's disease refractory and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: b-cell lymphoma, epstein-barr virus associated lymphoproliferative disorder. Vorinostat dosage: 300 MG ONCE DAILY ORAL. During the same period patient was treated with ASPIRIN. Patient recovered.



Vorinostat Side Effects Report #6129287-4
Vorinostat side effect was reported by a Pharmacist from UNITED STATES on Mar 23, 2009. Male patient, 68 years of age, was diagnosed with mycosis fungoides and was treated with Vorinostat. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, rash What is  rash. Vorinostat dosage: 200 MG EVERY DAY PO. Patient recovered.





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