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Wellbutrin Xr Side Effects

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Common Wellbutrin Xr Side Effects


The most commonly reported Wellbutrin Xr side effects are:
Achy And Soreness (6)
Soreness (6)
Tachycardia (1)
Severe Abdominal Cramping And Bloating (1)

If you have experienced a side effect listed above, you can check a box to report it.


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If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Wellbutrin Xr Side Effects Reported to FDA



Wellbutrin Xr Side Effect Report#9990269
Injection Site Pain
This is a report of a 56-year-old female patient (weight: NA) from Country Not Specified, suffering from the following health symptoms/conditions: NA, who was treated with Wellbutrin Xr (dosage: NA, start time:
Jul 23, 2013), combined with:
  • Folic Acid (I Think 1mg)
  • Estrogen
  • Losartan / Hydrochlorothiazid Stada (100/25mg)
  • Cymbalta
  • Humira
  • Methotrexate (Shots)
  • Opana Er
  • Salogen (felocarpine) (Up To 4 Times Daily)
and developed a serious reaction and side effect(s): Injection Site Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Wellbutrin Xr treatment in female patients, resulting in Injection Site Pain side effect.
Wellbutrin Xr Side Effect Report#9925105
Influenza Like Illness, Myalgia, Migraine, Palpitations, Oedema Peripheral, Feeling Jittery, Hangover
This report suggests a potential Wellbutrin Xr Influenza Like Illness side effect(s) that can have serious consequences. A 52-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Wellbutrin Xr (dosage: Take 1 Tablet In Am Daily) starting
Feb 24, 2014. After starting Wellbutrin Xr the patient began experiencing various side effects, including: Influenza Like Illness, Myalgia, Migraine, Palpitations, Oedema Peripheral, Feeling Jittery, HangoverAdditional drugs used concurrently: NA. Although Wellbutrin Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Influenza Like Illness, may still occur.
Wellbutrin Xr Side Effect Report#9776237
Pruritus, Eczema
This Pruritus problem was reported by a physician from SI. A 68-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Nov 05, 2013 this consumer started treatment with Wellbutrin Xr (dosage: NA). The following drugs were being taken at the same time:
  • Xarelto (rivaroxaban) (rivaroxaban)
  • Micardis (telmisartan) (telmisartan)
  • Darob Mite (sotalol Hydrochloride) (sotalol Hydrochloride)
  • Nexium
  • Doxazosin (doxazosin) (doxazosin)
  • Coryol (carvedilol) (carvedilol)
  • Tertensif (indapamide) (indapamide)
  • Lexaurin (bromazepam) (bromazepam)
When using Wellbutrin Xr, the patient experienced the following unwanted symptoms/side effects: Pruritus, EczemaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pruritus, may become evident only after a product is in use by the general population.
Wellbutrin Xr Side Effect Report#9553748
Mastitis
This Mastitis side effect was reported by a health professional from NL. A 51-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Wellbutrin Xr (drug dosage: NA), which was initiated on
Jul 08, 2013. Concurrently used drugs: NA..After starting to take Wellbutrin Xr the consumer reported adverse symptoms, such as: MastitisThese side effects may potentially be related to Wellbutrin Xr.
Wellbutrin Xr Side Effect Report#9413060
Transient Global Amnesia
This is a report of a 78-year-old female patient (weight: NA) from MT, suffering from the following health symptoms/conditions: depressive symptom, who was treated with Wellbutrin Xr (dosage: 150mg Per Day, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Transient Global Amnesia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Wellbutrin Xr treatment in female patients, resulting in Transient Global Amnesia side effect. The patient was hospitalized.
Wellbutrin Xr Side Effect Report#9286841
Poisoning Deliberate, Intentional Overdose, Mucosal Inflammation, Skin Irritation, Somnolence
This report suggests a potential Wellbutrin Xr Poisoning Deliberate side effect(s) that can have serious consequences. A 30-year-old female patient (weight: NA) from AT was diagnosed with the following symptoms/conditions: intentional overdose and used Wellbutrin Xr (dosage: 150 Mg, 20 In 1 D, Oral) starting
Oct 10, 2012. After starting Wellbutrin Xr the patient began experiencing various side effects, including: Poisoning Deliberate, Intentional Overdose, Mucosal Inflammation, Skin Irritation, SomnolenceAdditional drugs used concurrently: NA.The patient was hospitalized. Although Wellbutrin Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Poisoning Deliberate, may still occur.
Wellbutrin Xr Side Effect Report#9265849
Epilepsy, Loss Of Consciousness, Hyponatraemia, Musculoskeletal Stiffness, Dissociation, Fall, Hypotonia, Lethargy, Amnesia
This Epilepsy problem was reported by a physician from BE. A 58-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Feb 18, 2013 this consumer started treatment with Wellbutrin Xr (dosage: 150mg Per Day). The following drugs were being taken at the same time:
  • Tildiem
  • Medrol
  • Marcoumar
  • Stilnox (zolpidem)
  • Forteo
  • Calcium + Vitamin D
When using Wellbutrin Xr, the patient experienced the following unwanted symptoms/side effects: Epilepsy, Loss Of Consciousness, Hyponatraemia, Musculoskeletal Stiffness, Dissociation, Fall, Hypotonia, Lethargy, AmnesiaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Epilepsy, may become evident only after a product is in use by the general population.
Wellbutrin Xr Side Effect Report#9228302
Grand Mal Convulsion, Confusional State
This Grand Mal Convulsion side effect was reported by a consumer or non-health professional from US. A 72-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Wellbutrin Xr (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Wellbutrin Xr the consumer reported adverse symptoms, such as: Grand Mal Convulsion, Confusional StateThese side effects may potentially be related to Wellbutrin Xr. The patient was hospitalized.
Wellbutrin Xr Side Effect Report#9168138
Dry Mouth, Dysgeusia
This is a report of a 56-year-old female patient (weight: NA) from AT, suffering from the following health symptoms/conditions: NA, who was treated with Wellbutrin Xr (dosage: NA, start time: 201212), combined with:
  • Lyrica
  • Simethicone (simeticone) (simeticone)
  • Oestradiol Valerate (estradiol Valerate) (estradiol Valerate)
  • Pantoprazole (pantoprazole) (pantoprazole)
  • Colecalciferol (colecalciferol) (colecalciferol)
  • Nebivolol Hcl (nebivolol Hydrochloride) (nebivolol Hydrochloride)
  • Hydrochlorothiaz+olmesart (benicar Hct) (hydrochlorothiazide, Olmesartan Medoxomil)
and developed a serious reaction and side effect(s): Dry Mouth, Dysgeusia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Wellbutrin Xr treatment in female patients, resulting in Dry Mouth side effect.
Wellbutrin Xr Side Effect Report#9013739
Angina Pectoris, Fatigue, Insomnia, Incorrect Dose Administered
This report suggests a potential Wellbutrin Xr-bupropion Hydrochloride Angina Pectoris side effect(s) that can have serious consequences. A 20-year-old male patient (weight: NA) from PL was diagnosed with the following symptoms/conditions: NA and used Wellbutrin Xr-bupropion Hydrochloride (dosage: NA) starting NS. After starting Wellbutrin Xr-bupropion Hydrochloride the patient began experiencing various side effects, including: Angina Pectoris, Fatigue, Insomnia, Incorrect Dose AdministeredAdditional drugs used concurrently: NA. Although Wellbutrin Xr-bupropion Hydrochloride demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Angina Pectoris, may still occur.
Wellbutrin Xr Side Effect Report#6121151-X
Libido Increased, Sexual Abuse
This Libido Increased problem was reported by a physician from Switzerland. A 67-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Jun 19, 2008 this consumer started treatment with Wellbutrin Xr (dosage: 300mg Per Day). The following drugs were being taken at the same time:
  • Becozym Forte
  • Benerva (300mg Per Day)
  • Folic Acid (5mg Per Day)
  • Aspirin (300mg Per Day)
  • Plavix (75mg Per Day)
  • Trittico (100mg Per Day)
  • Trittico (200mg Per Day)
  • Oxazepam (45mg Per Day)
When using Wellbutrin Xr, the patient experienced the following unwanted symptoms/side effects: Libido Increased, Sexual AbuseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Libido Increased, may become evident only after a product is in use by the general population.
Wellbutrin Xr Side Effect Report#6111379-7
Completed Suicide
This Completed Suicide side effect was reported by a physician from Austria. A 64-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression,agitation,sleep disorder.The patient was prescribed Wellbutrin Xr (drug dosage: 150mg Twice Per Day), which was initiated on
Feb 03, 2009. Concurrently used drugs:
  • Risperdal (1mg Per Day)
  • Cisatracurium Besilate (45mg Per Day)
  • Abilify (5mg Per Day)
.After starting to take Wellbutrin Xr the consumer reported adverse symptoms, such as: Completed SuicideThese side effects may potentially be related to Wellbutrin Xr.
Wellbutrin Xr Side Effect Report#6101758-6
Blood Pressure Systolic Decreased, Cardiac Failure, Epilepsy, Intentional Overdose, Poisoning
This is a report of a 49-year-old female patient (weight: NA) from Belgium, suffering from the following health symptoms/conditions: depression, who was treated with Wellbutrin Xr (dosage: 100tab Per Day, start time: NS), combined with:
  • Trazolan
and developed a serious reaction and side effect(s): Blood Pressure Systolic Decreased, Cardiac Failure, Epilepsy, Intentional Overdose, Poisoning after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Wellbutrin Xr treatment in female patients, resulting in Blood Pressure Systolic Decreased side effect.
Wellbutrin Xr Side Effect Report#6097252-1
Epilepsy
This report suggests a potential Wellbutrin Xr Epilepsy side effect(s) that can have serious consequences. A 23-year-old male patient (weight: NA) from Switzerland was diagnosed with the following symptoms/conditions: mood swings and used Wellbutrin Xr (dosage: 450mg Per Day) starting
Sep 24, 2008. After starting Wellbutrin Xr the patient began experiencing various side effects, including: EpilepsyAdditional drugs used concurrently: NA. Although Wellbutrin Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Epilepsy, may still occur.
Wellbutrin Xr Side Effect Report#6094004-3
Completed Suicide
This Completed Suicide problem was reported by a physician from Austria. A 65-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: depression,agitation,sleep disorder. On
Jan 10, 2009 this consumer started treatment with Wellbutrin Xr (dosage: 300mg Per Day). The following drugs were being taken at the same time:
  • Risperdal (1mg Per Day)
  • Cisatracurium Besilate (30mg Per Day)
  • Abilify
When using Wellbutrin Xr, the patient experienced the following unwanted symptoms/side effects: Completed SuicideAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Completed Suicide, may become evident only after a product is in use by the general population.
Wellbutrin Xr Side Effect Report#6089072-9
Atrial Fibrillation, Atrioventricular Block, Cardiac Pacemaker Insertion
This Atrial Fibrillation side effect was reported by a physician from Greece. A 75-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Wellbutrin Xr (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Wellbutrin Xr the consumer reported adverse symptoms, such as: Atrial Fibrillation, Atrioventricular Block, Cardiac Pacemaker InsertionThese side effects may potentially be related to Wellbutrin Xr. The patient was hospitalized.
Wellbutrin Xr Side Effect Report#6079170-8
Hypertension, Palpitations, Sinus Tachycardia
This is a report of a 40-year-old female patient (weight: NA) from Netherlands, suffering from the following health symptoms/conditions: depression, who was treated with Wellbutrin Xr (dosage: 150mg Per Day, start time:
Nov 01, 2008), combined with:
  • Seroquel
  • Zolpidem
  • Nordette-28
  • Atenolol (25mg Twice Per Day)
and developed a serious reaction and side effect(s): Hypertension, Palpitations, Sinus Tachycardia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Wellbutrin Xr treatment in female patients, resulting in Hypertension side effect.
Wellbutrin Xr Side Effect Report#6062981-2
Blood Alkaline Phosphatase Increased, Blood Fibrinogen Increased, Blood Glucose Increased, Blood Triglycerides Increased, Blood Urea Increased, Cardiac Disorder, Cardiac Failure, Chest Pain, Dyspnoea
This report suggests a potential Wellbutrin Xr Blood Alkaline Phosphatase Increased side effect(s) that can have serious consequences. A 59-year-old male patient (weight: NA) from Belgium was diagnosed with the following symptoms/conditions: depression and used Wellbutrin Xr (dosage: 150mg In The Morning) starting
Sep 07, 2008. After starting Wellbutrin Xr the patient began experiencing various side effects, including: Blood Alkaline Phosphatase Increased, Blood Fibrinogen Increased, Blood Glucose Increased, Blood Triglycerides Increased, Blood Urea Increased, Cardiac Disorder, Cardiac Failure, Chest Pain, DyspnoeaAdditional drugs used concurrently:
  • Glucophage (850mg Twice Per Day)
  • Lipitor (20mg In The Morning)
  • Cardio-aspirine (100mg In The Morning)
  • Effexor (75mg Twice Per Day)
  • Aldactazine
  • Nexium (20mg Per Day)
  • Ramipril (10mg In The Morning)
  • Staurodorm
The patient was hospitalized and became disabled. Although Wellbutrin Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Alkaline Phosphatase Increased, may still occur.
Wellbutrin Xr Side Effect Report#5601316-3
Obesity, Urinary Retention
This Obesity problem was reported by a physician from Poland. A 39-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Oct 15, 2007 this consumer started treatment with Wellbutrin Xr (dosage: 300mg Per Day). The following drugs were being taken at the same time:
  • Buspirone Hydrochloride
  • Hydroxyzine
When using Wellbutrin Xr, the patient experienced the following unwanted symptoms/side effects: Obesity, Urinary RetentionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Obesity, may become evident only after a product is in use by the general population.
Wellbutrin Xr Side Effect Report#5431394-6
Mydriasis, Photosensitivity Reaction
This Mydriasis side effect was reported by a consumer or non-health professional from United States. A 35-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Wellbutrin Xr (drug dosage: 150mg Per Day), which was initiated on
May 02, 2007. Concurrently used drugs:
  • Lexapro
.After starting to take Wellbutrin Xr the consumer reported adverse symptoms, such as: Mydriasis, Photosensitivity ReactionThese side effects may potentially be related to Wellbutrin Xr.
Wellbutrin Xr Side Effect Report#5430792-4
Hyperhidrosis
This is a report of a 39-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: sleep disorder, who was treated with Wellbutrin Xr (dosage: 150mg Per Day, start time:
Nov 17, 2006), combined with:
  • Zocor
  • Aciphex
and developed a serious reaction and side effect(s): Hyperhidrosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Wellbutrin Xr treatment in male patients, resulting in Hyperhidrosis side effect.
Wellbutrin Xr Side Effect Report#10040634
Alopecia
This report suggests a potential Wellbutrin Xr Alopecia side effect(s) that can have serious consequences. A 48-year-old female patient (weight: NA) from CH was diagnosed with the following symptoms/conditions: depression and used Wellbutrin Xr (dosage: 1 Pil Per Day, Once Daily, Taken By Mouth) starting NS. After starting Wellbutrin Xr the patient began experiencing various side effects, including: AlopeciaAdditional drugs used concurrently: NA. Although Wellbutrin Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Alopecia, may still occur.



The appearance of Wellbutrin Xr on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


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It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Wellbutrin Xr reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    More About Wellbutrin xr

    Side Effects reported to FDA: 22

    Wellbutrin Xr safety alerts: No

    Reported deaths: 2

    Reported hospitalizations: 6

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