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Xefo Side Effects

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Common Xefo Side Effects


The most commonly reported Xefo side effects (click to view or check a box to report):

Rectal Cancer (1)
Pain In Extremity (1)
Disease Progression (1)


If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Xefo Side Effects Reported to FDA


Xefo Side Effect Report#7995966-7
Rectal Cancer, Disease Progression
This is a report of a 56-year-old male patient (weight: NA) from Austria, suffering from the following health symptoms/conditions: NA, who was treated with Xefo (dosage: 8 Mg, 2x/day, start time:
Sep 07, 2011), combined with:
  • Pantoprazole (40 Mg, 1x/day)
  • Irinotecan Hcl (180 Mg/m2, Every 2 Weeks)
  • Amitriptyline Hcl (25 Mg, 1x/day)
  • Metoclopramide Hydrochloride (25 Gtt, 3x/day)
  • Sucralfate (1g/5 Ml, Twice Daily)
  • Enalapril (5 Mg, 1x/day)
  • Avastin (5 Mg/kg, Every 2 Weeks)
  • Leucovorin Calcium (400 Mg/m2, Every 2 Weeks)
and developed a serious reaction and side effect(s): Rectal Cancer, Disease Progression after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Xefo treatment in male patients, resulting in Rectal Cancer side effect.
Xefo Side Effect Report#7583148-2
Pain In Extremity
This report suggests a potential Xefo Pain In Extremity side effect(s) that can have serious consequences. A female patient (weight: NA) from Austria was diagnosed with the following symptoms/conditions: pain,breast cancer,vitamin b complex deficiency,gastritis prophylaxis,hypothyroidism and used Xefo (dosage: As Required) starting
May 30, 2006. After starting Xefo the patient began experiencing various side effects, including: Pain In ExtremityAdditional drugs used concurrently:
  • Arimidex
  • Nerobin Forte
  • Pantoprazole Sodium
  • Euthyrox
  • Limbitrol
The patient was hospitalized. Although Xefo demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pain In Extremity, may still occur.



The appearance of Xefo on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Xefo Side Effects for Women?

Women Side EffectsReports
Pain In Extremity 1

What are common Xefo Side Effects for Men?

Men Side EffectsReports
Disease Progression 1
Rectal Cancer 1

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Xefo reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Xefo Safety Alerts, Active Ingredients, Usage Information

    More About Xefo

    Side Effects reported to FDA: 2

    Xefo safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 1

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