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Neuropathy (3)
Joint Swelling In Hand (2)
Toothache (2)
Vomiting (1)
Bloody Discharge (1)
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Xgeva Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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  Showing 101-125 of 277 

Osteoarthritis, Hip Arthroplasty (8225620-8)
on Mar 08, 2012 Female from AUSTRIA , 75 years of age, was diagnosed with
  • breast cancer
and was treated with Xgeva. Directly after, patient experienced the unwanted or unexpected Xgeva side effects: osteoarthritis, hip arthroplasty. Xgeva dosage: 60 Mg, Q6mo. Patient was hospitalized.

Cardiomegaly, Pain In Extremity, Skin Chapped, Pruritus, Chronic Obstructive Pulmonary Disease, Deep Vein Thrombosis, Rash, Oedema Peripheral (8225162-X)
Patient was taking Xgeva. Patient felt the following Xgeva side effects: cardiomegaly, pain in extremity, skin chapped, pruritus, chronic obstructive pulmonary disease, deep vein thrombosis, rash, oedema peripheral on Mar 16, 2012 from UNITED STATES Additional patient health information: Male , 66 years of age, weighting 161.0 lb, was diagnosed with
  • small cell lung cancer metastatic
and. Xgeva dosage: N/A.
Multiple prescriptions taken:
  • Zometa (Unk)
  • Lipitor
  • Amlodipine
  • Coumadin
  • Decadron (Unk)
Patient was hospitalized.

Hypophosphataemia, Hypocalcaemia, Neoplasm Malignant (8224587-6)
Adverse event was reported on Mar 14, 2012 by a Male taking Xgeva (Dosage: 120 Mg, Q4wk) was diagnosed with
  • metastases to bone
and. Location: UNITED STATES , 69 years of age, After Xgeva was administered, patient encountered several Xgeva side effects: hypophosphataemia, hypocalcaemia, neoplasm malignant. Patient was hospitalized.

Osteomyelitis, Bone Pain, Pain In Jaw, Osteonecrosis Of Jaw, Toothache (8223025-7)
on Mar 13, 2012 Female from UNITED STATES , 63 years of age, weighting 185.3 lb, was diagnosed with
  • metastases to bone
and was treated with Xgeva. Directly after, patient experienced the unwanted or unexpected Xgeva side effects: osteomyelitis, bone pain, pain in jaw, osteonecrosis of jaw, toothache. Xgeva dosage: 120 Mg, One Time Dose.
Associated medications used:
  • Pravachol (20 Mg, Qd)
  • Wellbutrin (150 Mg, Qd)
  • Calcium Carbonate (1000 Mg, Qd)
  • Vitamin B-12 (Unk Unk, Qd)
  • Faslodex (500 Mg, Qmo)
  • Norco (10 Mg, Qd)
  • Prilosec (20 Mg, Qd)
  • M.v.i. (Unk Unk, Qd)



Disease Progression, Hypocalcaemia (8220786-8)
on Mar 14, 2012 Male from UNITED STATES , weighting 200.0 lb, was diagnosed with
  • metastases to bone
and was treated with Xgeva. Patient felt the following Xgeva side effects: disease progression, hypocalcaemia. Xgeva dosage: 120 Mg, Q4wk. Patient was hospitalized.

Hyperkalaemia, Blood Creatinine Abnormal, Hypocalcaemia, Blood Urea Abnormal (8218181-0)
Patient was taking Xgeva. After Xgeva was administered, patient encountered several Xgeva side effects: hyperkalaemia, blood creatinine abnormal, hypocalcaemia, blood urea abnormal on Mar 12, 2012 from UNITED STATES Additional patient health information: Male , weighting 145.0 lb, . Xgeva dosage: Unk Unk, One Time Dose.
Multiple concurrent drugs taken:
  • Prilosec
  • Terazosin Hcl
Patient was hospitalized.

Bundle Branch Block, Hypoaesthesia, Hypocalcaemia (8216696-2)
Adverse event was reported on Mar 13, 2012 by a Male taking Xgeva (Dosage: N/A) was diagnosed with
  • prophylaxis
and. Location: UNITED STATES , 70 years of age, Directly after, patient experienced the unwanted or unexpected Xgeva side effects: bundle branch block, hypoaesthesia, hypocalcaemia.
Associated medications used:
  • Calcium Carbonate (1500 Mg, Qd)
  • Lupron
Patient was hospitalized.

Renal Failure Acute, Pneumonia Aspiration (8215134-3)
on Mar 05, 2012 Male from CANADA , 87 years of age, was diagnosed with
  • prostate cancer
and was treated with Xgeva. Patient felt the following Xgeva side effects: renal failure acute, pneumonia aspiration. Xgeva dosage: 1 Ml, Q4wk. Patient was hospitalized.

Lower Limb Fracture, Hypercalcaemia, Hypophosphataemia, Vomiting, Fall (8206916-2)
on Mar 02, 2012 Male from UNITED STATES , child 9 years of age, was diagnosed with
  • fibrous dysplasia of bone
and was treated with Xgeva. After Xgeva was administered, patient encountered several Xgeva side effects: lower limb fracture, hypercalcaemia, hypophosphataemia, vomiting, fall. Xgeva dosage: 1.0 Mg, One Time Dose. Patient was hospitalized.

(8205101-8)
Patient was taking Xgeva. on Mar 09, 2012 from CANADA Additional patient health information: Female , 73 years of age, . Xgeva dosage: N/A.

Osteonecrosis Of Jaw, Eating Disorder, Oral Discomfort, Temporomandibular Joint Syndrome, Stomatitis (8204648-8)
Adverse event was reported on Mar 08, 2012 by a Male taking Xgeva (Dosage: 120 Mg, Unk) . Location: CANADA , 78 years of age, Patient felt the following Xgeva side effects: osteonecrosis of jaw, eating disorder, oral discomfort, temporomandibular joint syndrome, stomatitis.

(8203389-0)
on Mar 08, 2012 Female from UNITED STATES , 56 years of age, was diagnosed with
  • prophylaxis
and was treated with Xgeva. . Xgeva dosage: N/A.

Cough, Chest Discomfort, Respiratory Distress, Dyspnoea (8202291-8)
on Mar 05, 2012 Female from UNITED STATES , 37 years of age, weighting 105.8 lb, was diagnosed with
  • breast cancer
and was treated with Xgeva. Directly after, patient experienced the unwanted or unexpected Xgeva side effects: cough, chest discomfort, respiratory distress, dyspnoea. Xgeva dosage: 120 Mug, Q4wk.
Associated medications used:
  • Decadron (Unk)
  • Ativan (Unk)
  • Senna
  • Oxycontin (Unk)
  • Marinol (Unk)
  • Ambien
  • Senna Lax (Unk)
  • Diflucan Duo (Unk)
Patient was hospitalized.

Pain In Extremity, Chronic Obstructive Pulmonary Disease, Oedema Peripheral, Cardiomegaly, Skin Chapped, Pruritus, Deep Vein Thrombosis (8199670-4)
Patient was taking Xgeva. Patient felt the following Xgeva side effects: pain in extremity, chronic obstructive pulmonary disease, oedema peripheral, cardiomegaly, skin chapped, pruritus, deep vein thrombosis on Mar 07, 2012 from UNITED STATES Additional patient health information: Male , 66 years of age, weighting 161.0 lb, was diagnosed with
  • metastases to bone
and. Xgeva dosage: 120 Mg, Q4wk.
Multiple prescriptions taken:
  • Lipitor
  • Symbicort
  • Aloxi (Unk)
  • Metoprolol Succinate
  • Ventolin
  • Decadron (Unk)
  • Amlodipine
  • Coumadin
Patient was hospitalized.

(8199424-9)
Adverse event was reported on Mar 08, 2012 by a Female taking Xgeva (Dosage: 120 Mg, Qmo) . Location: UNITED STATES , 53 years of age, weighting 98.98 lb, .
Multiple concurrent drugs taken:
  • Navelbine (40 Mg, Qwk)
  • Carboplatin (465 Mg, Unk)
  • Xeloda (1000 Mg, Bid)
  • Adriamycin Pfs (20 Mg, Qwk)
  • Gemzar (1266 Mg, Unk)


Pain In Extremity, Meningitis, Metastatic Neoplasm (8198944-0)
on Mar 06, 2012 Female from UNITED STATES , 60 years of age, was diagnosed with
  • breast cancer
and was treated with Xgeva. Directly after, patient experienced the unwanted or unexpected Xgeva side effects: pain in extremity, meningitis, metastatic neoplasm. Xgeva dosage: Unk.

Croup Infectious, Seborrhoeic Dermatitis, Otitis Media, Upper Respiratory Tract Infection, Viral Upper Respiratory Tract Infection (8198539-9)
on Jan 03, 2012 Male from UNITED STATES , weighting 23.80 lb, was treated with Xgeva. Patient felt the following Xgeva side effects: croup infectious, seborrhoeic dermatitis, otitis media, upper respiratory tract infection, viral upper respiratory tract infection. Xgeva dosage: Unk.

Oral Mucosal Erythema, Gingival Pain (8198083-9)
Patient was taking Xgeva. After Xgeva was administered, patient encountered several Xgeva side effects: oral mucosal erythema, gingival pain on Jan 17, 2012 from UNITED STATES Additional patient health information: Female , 64 years of age, was diagnosed with
  • breast cancer
and. Xgeva dosage: Unk Unk, Q6wk.
Multiple concurrent drugs taken:
  • Synthroid (1 Unk, Unk)


Tooth Extraction (8198073-6)
Adverse event was reported on Feb 09, 2012 by a Male taking Xgeva (Dosage: 120 Mg, Q4wk) was diagnosed with
  • neoplasm
and. Location: UNITED STATES , 85 years of age, Directly after, patient experienced the unwanted or unexpected Xgeva side effects: tooth extraction.

Rash (8198072-4)
on Feb 22, 2012 Female from UNITED STATES , 68 years of age, weighting 145.5 lb, was diagnosed with
  • breast cancer metastatic
and was treated with Xgeva. Patient felt the following Xgeva side effects: rash. Xgeva dosage: 120 Mg, Qmo.
Multiple prescriptions taken:
  • Faslodex (Unk)


Blood Calcium Decreased (8198068-2)
on Feb 23, 2012 Male from UNITED STATES , 87 years of age, weighting 150.1 lb, was diagnosed with
  • prophylaxis
  • prostate cancer
and was treated with Xgeva. After Xgeva was administered, patient encountered several Xgeva side effects: blood calcium decreased. Xgeva dosage: 120 Mg, Q4wk.
Multiple concurrent drugs taken:
  • Taxotere (71.6 Mg, Q3wk)
  • Prednisone (5 Mg, Bid)


Insomnia, Back Pain, Initial Insomnia, Hot Flush (8198065-7)
Patient was taking Xgeva. Directly after, patient experienced the unwanted or unexpected Xgeva side effects: insomnia, back pain, initial insomnia, hot flush on Feb 17, 2012 from UNITED STATES Additional patient health information: Male , 67 years of age, was diagnosed with
  • metastases to bone
and. Xgeva dosage: N/A.
Associated medications used:
  • Calcium
  • Trelstar
  • Fish Oil
  • Trelstar (Unk)
  • Lisinopril Combino (Unk)
  • Vitamin D
  • Omeprazole (Unk)
  • Zolpidem


Pain In Jaw (8198062-1)
Adverse event was reported on Feb 16, 2012 by a Female taking Xgeva (Dosage: 120 Mg, Qmo) was diagnosed with
  • lung neoplasm malignant
and. Location: UNITED STATES , 72 years of age, weighting 134.5 lb, Patient felt the following Xgeva side effects: pain in jaw.
Multiple prescriptions taken:
  • Tarceva (100 Mg, Qd)
  • Aredia (90 Mg, Unk)
  • Aredia (60 Mg, Unk)


Vision Blurred (8198060-8)
on Feb 13, 2012 Male from UNITED STATES , 84 years of age, was diagnosed with
  • prostate cancer metastatic
and was treated with Xgeva. After Xgeva was administered, patient encountered several Xgeva side effects: vision blurred. Xgeva dosage: Unk.
Multiple concurrent drugs taken:
  • Hormones (Unk)
  • Toviaz (Unk)


Hypocalcaemia, Hypophosphataemia (8198056-6)
on Feb 17, 2012 Male from UNITED STATES , 74 years of age, was treated with Xgeva. Directly after, patient experienced the unwanted or unexpected Xgeva side effects: hypocalcaemia, hypophosphataemia. Xgeva dosage: N/A.

  Showing 101-125 of 277 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Xgeva Information

Alternative XGEVA Names:DENOSUMAB

Active Ingredient: DENOSUMAB

More About Xgeva

Side Effects reported to FDA: 277. View Xgeva Adverse Reports

Xgeva safety alerts: No

Reported deaths: 34

Reported hospitalizations: 102

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