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Tired (3)
Palpitations (2)
Sleep Disturbance (1)
Weight Gain (1)
Doe It Raise Blood Pressure (1)
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MEMORY LOSS (1)
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Zoplicone Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Pulmonary Embolism, Suicide Attempt, Intentional Overdose (8322722-2)
on Apr 26, 2012 Female from FRANCE , 33 years of age, was treated with Zoplicone. Directly after, patient experienced the unwanted or unexpected Zoplicone side effects: pulmonary embolism, suicide attempt, intentional overdose. Zoplicone dosage: N/A.
Associated medications used:
  • Xanax
  • Lepticur
  • Loxapine Hcl
  • Quetiapine Fumarate
  • Zolpidem
Patient was hospitalized.

Enuresis, Hyponatraemia, Disorientation, Vomiting, Sedation (8274341-4)
Patient was taking Zoplicone. Patient felt the following Zoplicone side effects: enuresis, hyponatraemia, disorientation, vomiting, sedation on Apr 02, 2012 from FRANCE Additional patient health information: Male , weighting 160.9 lb, . Zoplicone dosage: Started At Least In 2004.
Multiple prescriptions taken:
  • Surfalem S25 (Started At Least In 2004)
  • Parkinane Lp
  • Alfuzosin Hcl
  • Quetiapine Fumarate
  • Depakote (Started At Least In 2003)
  • Metformin Hcl (700 Mg Per Tablet, 1/2 Tablet Trhee Times Per Day)
Patient was hospitalized.

Anaphylactic Reaction (8262949-1)
Adverse event was reported on Mar 30, 2012 by a Male taking Zoplicone (Dosage: N/A) . Location: UNITED KINGDOM , 28 years of age, weighting 176.4 lb, After Zoplicone was administered, patient encountered several Zoplicone side effects: anaphylactic reaction.
Multiple concurrent drugs taken:
  • Acetaminophen (4 Times A Day When Required)
  • Vitamins Nos (Capsules)
  • Sodium Chloride
  • Aztreonam
  • Azithromycin (Taken On Mondays, Wednesdays, Fridays)
  • Creon
  • Minocycline Hydrochloride
  • Heparin


Pulmonary Embolism, Intentional Overdose, Suicide Attempt (8238370-9)
on Mar 23, 2012 Female from FRANCE , 33 years of age, was treated with Zoplicone. Directly after, patient experienced the unwanted or unexpected Zoplicone side effects: pulmonary embolism, intentional overdose, suicide attempt. Zoplicone dosage: N/A.
Associated medications used:
  • Quetiapine Fumarate
  • Zolpidem
  • Xanax
  • Lepticur
  • Loxapine Hcl
Patient was hospitalized.


Spinal Laminectomy (7788376-9)
on Sep 19, 2011 Male from CANADA , weighting 177.7 lb, was treated with Zoplicone. Patient felt the following Zoplicone side effects: spinal laminectomy. Zoplicone dosage: At Bedtime.
Multiple prescriptions taken:
  • Extra Strength Tylenol
  • Rabeprazole Sodium
  • Methotrexate
  • Terbinafine Hcl
  • Naproxen
  • Remicade
  • Remicade (41st Infusion)
  • Remicade
Patient was hospitalized.

Infection, Diarrhoea, Pneumonia, Disease Recurrence, Cytomegalovirus Test Positive, Sepsis, Acute Graft Versus Host Disease, Staphylococcal Infection, Cytomegalovirus Colitis (7758430-6)
Patient was taking Zoplicone. After Zoplicone was administered, patient encountered several Zoplicone side effects: infection, diarrhoea, pneumonia, disease recurrence, cytomegalovirus test positive, sepsis, acute graft versus host disease, staphylococcal infection, cytomegalovirus colitis on Sep 09, 2011 from AUSTRALIA Additional patient health information: Male , weighting 242.5 lb, was diagnosed with
  • insomnia
  • vitamin supplementation
and. Zoplicone dosage: Unk.
Multiple concurrent drugs taken:
  • Folic Acid (5 Mg, Qd)
  • Piperacillin And Tazobactam (4.5 G, Tid)
  • Pantoprazole
  • Phenergan Hcl (25 Mg, Unk)
  • Azithromycin (500 Mg, Qd)
  • Pantoprazole (40 Mg, Bid)
  • Vitamin K Tab (10 Mg, 3x/w)
  • Thymoglobulin (.5 Mg/kg, Unk)
Patient was hospitalized.

Ventricular Fibrillation, Electrocardiogram Qt Prolonged, Blood Pressure Decreased, Jugular Vein Distension, Hypokalaemia, Hyperlactacidaemia, Convulsion, Oxygen Saturation Decreased, Metabolic Acidosis (7755684-7)
Adverse event was reported on Sep 01, 2011 by a Female taking Zoplicone (Dosage: N/A) . Location: DENMARK , 54 years of age, Directly after, patient experienced the unwanted or unexpected Zoplicone side effects: ventricular fibrillation, electrocardiogram qt prolonged, blood pressure decreased, jugular vein distension, hypokalaemia, hyperlactacidaemia, convulsion, oxygen saturation decreased, metabolic acidosis.
Associated medications used:
  • Alcohol (ethanol)
  • Citalopram Hydrobromide
Patient was hospitalized.

Flushing, Infusion Related Reaction, Chest Discomfort, Obesity, Arthralgia (7718131-7)
on Aug 22, 2011 Female from CANADA , weighting 196.7 lb, was treated with Zoplicone. Patient felt the following Zoplicone side effects: flushing, infusion related reaction, chest discomfort, obesity, arthralgia. Zoplicone dosage: N/A.
Multiple prescriptions taken:
  • Remicade
  • Methotrexate
  • Perindopril Erbumine
  • Escitalopram
  • Remicade
  • Hydrochlorothiazide
  • Crestor
  • Folic Acid


Pneumonia, Computerised Tomogram (7646509-9)
on Jul 19, 2011 Female from CANADA , 46 years of age, weighting 119.0 lb, was treated with Zoplicone Wellbutrin Fluoxetine Valacyclovir. After Zoplicone was administered, patient encountered several Zoplicone side effects: pneumonia, computerised tomogram. Zoplicone Wellbutrin Fluoxetine Valacyclovir dosage: N/A.
Multiple concurrent drugs taken:
  • Seroquel
Patient was hospitalized.

Elevated Mood, Dysarthria, Salivary Hypersecretion (7605344-8)
Patient was taking Zoplicone. Directly after, patient experienced the unwanted or unexpected Zoplicone side effects: elevated mood, dysarthria, salivary hypersecretion on Jul 01, 2011 from UNITED KINGDOM Additional patient health information: Male , 86 years of age, . Zoplicone dosage: 3.75 Mg, Qd.
Associated medications used:
  • Docusate (100 Mg, Bid)
  • Lithium Carbonate (200 Mg, Qd)
  • Ramipril (1.25 Mg, Qd)
  • Senna (15 Mg, Qd)
  • Clopidogrel (75 Mg, Qd)
  • Folic Acid (5 Mg, Qd)
  • Bumetanide (2 Mg, Qd)
  • Metoprolol Tartrate (25 Mg, Tid)
Patient was hospitalized and became disabled.

Deep Vein Thrombosis (7338572-X)
Adverse event was reported on Feb 23, 2011 by a Male taking Zoplicone (Dosage: N/A) . Location: IRELAND , 48 years of age, Patient felt the following Zoplicone side effects: deep vein thrombosis.
Multiple prescriptions taken:
  • Zyprexa
  • Ramipril
  • Lithium Carbonate


Confusional State (7274747-6)
on Jan 31, 2011 Male from CANADA , 56 years of age, weighting 156.5 lb, was treated with Zoplicone. After Zoplicone was administered, patient encountered several Zoplicone side effects: confusional state. Zoplicone dosage: Unk.
Multiple concurrent drugs taken:
  • Hydromorphone Hcl (Unk)
  • Nystatin (100000 Ml, Qid)
  • Xylocaine (Unk)
  • Flagyl (500 Mg, Tid)
  • Panitumumab (557 Mg, Q3wk)
  • Ativan (1 Mg, Prn)
  • Citalopram (20 Mg, Qd)
Patient was hospitalized.

Atrioventricular Block First Degree, Blood Glucose Increased, Hypotension (5578053-7)
on Dec 10, 2007 Male from UNITED KINGDOM , 52 years of age, was treated with Zoplicone (zoplicone). Directly after, patient experienced the unwanted or unexpected Zoplicone side effects: atrioventricular block first degree, blood glucose increased, hypotension. Zoplicone (zoplicone) dosage: 37.5 Mg; 1x; Po.
Associated medications used:
  • Atenolol (2000 Mg; Po; 1x)
  • Losartan Potassium (2000 Mg; Po; 1x; Po)
  • Amlodipine Besylate (325 Mg; Po; 1x)
Patient was hospitalized.

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Zoplicone Information

More About Zoplicone

Side Effects reported to FDA: 13. View Zoplicone Adverse Reports

Zoplicone safety alerts: No

Reported deaths: 3

Reported hospitalizations: 8

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