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Zyloric Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 66 

Agranulocytosis, Diarrhoea, Neutropenia, Pyrexia (7043610-8)
on Oct 05, 2010 Female from JAPAN , 60 years of age, was treated with Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: agranulocytosis, diarrhoea, neutropenia, pyrexia. Zyloric dosage: 100mg Per Day.
Associated medications used:
  • Furosemide (80mg Per Day)
  • Artist (10mg Per Day)
  • Mexitil (300mg Per Day)
  • Fluvastatin (20mg Per Day)
  • Selbex (150mg Per Day)
  • Amlodipine Besylate (5mg Per Day)
  • Predonine (8mg Per Day)
  • Warfarin Sodium (1.5mg Per Day)
Patient was hospitalized.

Cough, Decreased Appetite, Interstitial Lung Disease, Malaise, Pleural Effusion, Pneumonia, Pneumonitis (6871801-5)
Patient was taking Zyloric. Patient felt the following Zyloric side effects: cough, decreased appetite, interstitial lung disease, malaise, pleural effusion, pneumonia, pneumonitis on Jul 12, 2010 from JAPAN Additional patient health information: Male , weighting 136.7 lb, was diagnosed with
  • hyperuricaemia
  • depression
  • arteriosclerosis obliterans
  • gastric ulcer
  • hypercholesterolaemia
  • cardiac failure
  • gastritis
and. Zyloric dosage: 200mg Per Day.
Multiple prescriptions taken:
  • Paxil (20mg Per Day)
  • Plavix (75mg Per Day)
  • Takepron (15mg Per Day)
  • Fluvastatin (20mg Per Day)
  • Diovan (80mg Per Day)
  • Dogmatyl (50mg Per Day)
  • Aldactone
  • Amaryl
Patient was hospitalized.

Hypoprothrombinaemia, Renal Failure, Shock (6527177-6)
Adverse event was reported on Dec 28, 2009 by a Male taking Zyloric (Dosage: 100mg Per Day) . Location: FRANCE , 84 years of age, After Zyloric was administered, patient encountered several Zyloric side effects: hypoprothrombinaemia, renal failure, shock.
Multiple concurrent drugs taken:
  • Amoxicillin And Clavulanate Potassium (1g Three Times Per Day)
  • Previscan (10mg Per Day)
  • Colchimax
Patient was hospitalized.

Hypoprothrombinaemia, Renal Failure, Shock (6522339-6)
on Dec 28, 2009 Male from FRANCE , 84 years of age, was treated with Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: hypoprothrombinaemia, renal failure, shock. Zyloric dosage: 100mg Per Day.
Associated medications used:
  • Amoxicillin And Clavulanate Potassium (1g Three Times Per Day)
  • Previscan (10mg Per Day)
  • Colchimax
Patient was hospitalized.


Cytolytic Hepatitis, Hypersensitivity, Jaundice, Pyrexia, Rash Erythematous, Renal Failure Acute, Tubulointerstitial Nephritis (6359848-9)
on Sep 11, 2009 Male from FRANCE , 54 years of age, was treated with Zyloric. Patient felt the following Zyloric side effects: cytolytic hepatitis, hypersensitivity, jaundice, pyrexia, rash erythematous, renal failure acute, tubulointerstitial nephritis. Zyloric dosage: N/A.
Multiple prescriptions taken:
  • Icaz
  • Tahor
Patient was hospitalized.

Cytolytic Hepatitis, Hypersensitivity, Jaundice, Pyrexia, Rash Erythematous, Renal Failure Acute, Tubulointerstitial Nephritis (6311646-8)
Patient was taking Zyloric. After Zyloric was administered, patient encountered several Zyloric side effects: cytolytic hepatitis, hypersensitivity, jaundice, pyrexia, rash erythematous, renal failure acute, tubulointerstitial nephritis on Aug 13, 2009 from FRANCE Additional patient health information: Male , 54 years of age, was diagnosed with
  • hyperuricaemia
  • hypertension
and. Zyloric dosage: N/A.
Multiple concurrent drugs taken:
  • Icaz
  • Tahor
Patient was hospitalized.

Blood Creatinine Increased, Toxic Epidermal Necrolysis, Urea Urine Increased (6214807-1)
Adverse event was reported on May 27, 2009 by a Male taking Zyloric (Dosage: 300mg Per Day) was diagnosed with
  • gout
and. Location: SPAIN , 86 years of age, Directly after, patient experienced the unwanted or unexpected Zyloric side effects: blood creatinine increased, toxic epidermal necrolysis, urea urine increased.
Associated medications used:
  • Requip
  • Haloperidol
  • Tramadol Hcl
  • Adiro
  • Pantoprazole Sodium
  • Aricept
  • Atacand
  • Enoxaparin Sodium


Anuria, Dermatitis Bullous, Dermatitis Exfoliative, Erythema, Face Oedema, Mucous Membrane Disorder, Pyrexia, Skin Disorder (6126195-X)
on Mar 19, 2009 Female from FRANCE , 90 years of age, was treated with Zyloric. Patient felt the following Zyloric side effects: anuria, dermatitis bullous, dermatitis exfoliative, erythema, face oedema, mucous membrane disorder, pyrexia, skin disorder. Zyloric dosage: 100mg Per Day.
Multiple prescriptions taken:
  • Augmentin '125'
  • Rulid
  • Aprovel (300mg Per Day)
  • Lasix (120mg Per Day)
  • Levothyroxine Sodium (50mcg Per Day)
  • Vastarel (70mg Per Day)
  • Lipanthyl (67mg Per Day)
Patient was hospitalized.

Dermatitis Exfoliative, Epidermal Necrosis (6109424-8)
on Mar 04, 2009 Female from FRANCE , 74 years of age, was treated with Zyloric. After Zyloric was administered, patient encountered several Zyloric side effects: dermatitis exfoliative, epidermal necrosis. Zyloric dosage: 100mg Twice Per Day.
Multiple concurrent drugs taken:
  • Augmentin '125' (1g Three Times Per Day)
  • Betadine
  • Colchimax
  • Orbenine
Patient was hospitalized.

Dermatitis Exfoliative, Eosinophilia, Face Oedema, Lymphadenopathy, Pruritus, Pyrexia, Rash Maculo-papular, Urticaria (6092304-4)
Patient was taking Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: dermatitis exfoliative, eosinophilia, face oedema, lymphadenopathy, pruritus, pyrexia, rash maculo-papular, urticaria on Feb 17, 2009 from FRANCE Additional patient health information: Male , 63 years of age, . Zyloric dosage: 300mg Per Day.
Associated medications used:
  • Augmentin '125'
  • Revlimid (25mg Per Day)
  • Imovane
  • Lexomil
  • Lytos
  • Ogast
  • Skenan
  • Morphine
Patient was hospitalized.

Stevens-johnson Syndrome (6084488-9)
Adverse event was reported on Feb 09, 2009 by a Female taking Zyloric (Dosage: N/A) was diagnosed with
  • blood test abnormal
  • cough
  • iron deficiency anaemia
and. Location: SPAIN , 85 years of age, Patient felt the following Zyloric side effects: stevens-johnson syndrome.
Multiple prescriptions taken:
  • Sekisan (45 Ml Cyclique)
  • Fero-gradumet (Unk)
  • Adiro
  • Seguril
  • Stilnox (Unk)
  • Fluimucil
  • Zantac
  • Nitradisc


Aplastic Anaemia, Bicytopenia, Dyspnoea, Ecchymosis, Haematoma, Petechiae, Pneumonia, Pyrexia, Renal Failure (6084426-9)
on Feb 11, 2009 Female from SPAIN , 74 years of age, was treated with Zyloric. After Zyloric was administered, patient encountered several Zyloric side effects: aplastic anaemia, bicytopenia, dyspnoea, ecchymosis, haematoma, petechiae, pneumonia, pyrexia, renal failure. Zyloric dosage: 300mg Per Day.
Multiple concurrent drugs taken:
  • Torsemide (10mg Per Day)
  • Amlodipine
  • Simvastatin (20mg Per Day)
  • Metformin Hcl (1700mg Per Day)
  • Adiro (300mg Per Day)
  • Cozaar (50mg Per Day)
  • Esberiven


Arthralgia, Dyshidrosis, Pruritus, Rash (6051571-3)
on Jan 19, 2009 Male from FRANCE , 77 years of age, was treated with Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: arthralgia, dyshidrosis, pruritus, rash. Zyloric dosage: N/A.
Associated medications used:
  • Clamoxyl (4g Per Day)
  • Diltiazem Hcl
  • Captopril And Hydrochlorothiazide
  • Xatral
  • Kardegic
  • Dermocorticoid
Patient was hospitalized.

Stevens-johnson Syndrome (5989358-X)
Patient was taking Zyloric. Patient felt the following Zyloric side effects: stevens-johnson syndrome on Nov 28, 2008 from SPAIN Additional patient health information: Female , 85 years of age, was diagnosed with
  • blood test abnormal
  • cardiomyopathy
  • cough
and. Zyloric dosage: N/A.
Multiple prescriptions taken:
  • Zantac
  • Sekisan
  • Nitradisc
  • Fero-gradumet (Unk)
  • Aspirin
  • Seguril
  • Zolpidem (Unk)
  • Acetylcysteine


Pancytopenia (5807203-X)
Adverse event was reported on Jul 08, 2008 by a Female taking Zyloric (Dosage: 100mg Per Day) . Location: JAPAN , 94 years of age, After Zyloric was administered, patient encountered several Zyloric side effects: pancytopenia.
Multiple concurrent drugs taken:
  • Digosin
  • Warfarin Sodium
  • Vasolan
  • Diart
  • Amlodipine


Toxic Epidermal Necrolysis (5674701-1)
on Mar 13, 2008 Female from FRANCE , 80 years of age, was treated with Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: toxic epidermal necrolysis. Zyloric dosage: N/A.
Associated medications used:
  • Augmentin '125'


Acidosis, Asthenia, Bradycardia, Coma, Dehydration, Hyperkalaemia, Hyperlactacidaemia, Lymphoedema, Malaise (5632095-1)
on Feb 12, 2008 Female from FRANCE , 84 years of age, was treated with Zyloric. Patient felt the following Zyloric side effects: acidosis, asthenia, bradycardia, coma, dehydration, hyperkalaemia, hyperlactacidaemia, lymphoedema, malaise. Zyloric dosage: 200mg Per Day.
Multiple prescriptions taken:
  • Seretide Diskus
  • Aldactone (12.5mg Per Day)
  • Ramipril (1.25mg Per Day)
  • Lasilix
  • Acebutolol (200mg Per Day)
  • Amlor (5mg Twice Per Day)
  • Plavix (75mg Per Day)
  • Kardegic (160mg Per Day)
Patient was hospitalized.

Bronchiectasis, Interstitial Lung Disease, Lymphadenopathy, Pseudolymphoma, Skin Lesion (5564549-0)
Patient was taking Zyloric. After Zyloric was administered, patient encountered several Zyloric side effects: bronchiectasis, interstitial lung disease, lymphadenopathy, pseudolymphoma, skin lesion on Dec 10, 2007 from FRANCE Additional patient health information: Male , 74 years of age, was diagnosed with
  • blood uric acid increased
and. Zyloric dosage: 1 Df, Qd. Patient was hospitalized.

Hypoaesthesia, Pain In Extremity, Pallanaesthesia, Paraesthesia, Polyneuropathy Idiopathic Progressive, Red Blood Cell Sedimentation Rate Increased, Sensory Disturbance (5537404-X)
Adverse event was reported on Nov 28, 2007 by a Female taking Zyloric (Dosage: 300mg Per Day) . Location: FRANCE , 75 years of age, Directly after, patient experienced the unwanted or unexpected Zyloric side effects: hypoaesthesia, pain in extremity, pallanaesthesia, paraesthesia, polyneuropathy idiopathic progressive, red blood cell sedimentation rate increased, sensory disturbance.
Associated medications used:
  • Seretide (1unit Twice Per Day)
  • Co-aprovel
  • Eupressyl (60mg Per Day)
  • Kardegic (75mg Per Day)
Patient was hospitalized.

Agranulocytosis, Mitral Valve Incompetence, Neutrophil Count Decreased, Pyrexia, Rash Papulosquamous (5480582-1)
on Oct 04, 2007 Male from SPAIN , 53 years of age, was diagnosed with
  • hyperuricaemia
  • hyperthyroidism
  • cardiac failure congestive
and was treated with Zyloric. Patient felt the following Zyloric side effects: agranulocytosis, mitral valve incompetence, neutrophil count decreased, pyrexia, rash papulosquamous. Zyloric dosage: 300mg Per Day.
Multiple prescriptions taken:
  • Tirodril (5mg Per Day)
  • Renitec (5mg Per Day)
  • Seguril (300mg Per Day)
  • Chlorthalidone (50mg Per Day)
  • Coropres (12.5mg Per Day)
Patient was hospitalized.

Agranulocytosis, Neutrophil Count Decreased, Pyrexia, Rash Papulosquamous (5480466-9)
on Oct 04, 2007 Male from SPAIN , 53 years of age, was treated with Zyloric. After Zyloric was administered, patient encountered several Zyloric side effects: agranulocytosis, neutrophil count decreased, pyrexia, rash papulosquamous. Zyloric dosage: 300mg Per Day.
Multiple concurrent drugs taken:
  • Tirodril (5mg Per Day)
  • Renitec (5mg Per Day)
  • Seguril (300mg Per Day)
  • Chlorthalidone (50mg Per Day)
  • Coropres (12.5mg Per Day)
Patient was hospitalized.

Cheilitis, Conjunctival Oedema, Cytomegalovirus Antibody Positive, Epstein-barr Virus Antibody Positive, Erythema, Erythema Of Eyelid, Herpes Simplex Serology Negative, Lip Blister, Liver Disorder (5103870-7)
Patient was taking Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: cheilitis, conjunctival oedema, cytomegalovirus antibody positive, epstein-barr virus antibody positive, erythema, erythema of eyelid, herpes simplex serology negative, lip blister, liver disorder on Aug 21, 2006 from JAPAN Additional patient health information: Male , 63 years of age, weighting 136.7 lb, . Zyloric dosage: 100mg Three Times Per Day.
Associated medications used:
  • Diclofenac (25mg Three Times Per Day)
  • Cimetidine (200mg Three Times Per Day)
  • Bayaspirin (100mg Per Day)
  • Blopress (8mg Per Day)
  • Tripamide (15mg Per Day)
  • Tagamet
  • Voltaren
Patient was hospitalized.

Blood Creatinine Increased, Blood Pressure Systolic Decreased, Blood Urea Increased, Shock, Urinary Retention (4977828-2)
Adverse event was reported on Apr 10, 2006 by a Male taking Zyloric (Dosage: 2 Df, Unk) . Location: JAPAN , 43 years of age, Patient felt the following Zyloric side effects: blood creatinine increased, blood pressure systolic decreased, blood urea increased, shock, urinary retention.
Multiple prescriptions taken:
  • Urso (300 Mg, Unk)
  • Diovan (40 Mg, Qd)
Patient was hospitalized.

Lung Infiltration, Nasopharyngitis, Pancytopenia, Pneumonia, Respiratory Failure (4961772-0)
on Feb 10, 2006 Female from JAPAN , 82 years of age, was diagnosed with
  • hyperuricaemia
  • hypertension
  • pneumonia
  • neutropenia
  • chronic myeloid leukaemia
and was treated with Zyloric. After Zyloric was administered, patient encountered several Zyloric side effects: lung infiltration, nasopharyngitis, pancytopenia, pneumonia, respiratory failure. Zyloric dosage: 200 Mg/day.
Multiple concurrent drugs taken:
  • Adalat (40 Mg/day)
  • Carbenin (1 G/day)
  • Gran (200 Ug/d)
  • Gleevec (400 Mg/day)
  • Gleevec (200 Mg/day)
Patient was hospitalized.

Aphthous Stomatitis, Aspartate Aminotransferase Decreased, Blood Creatinine Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Blood Urea Increased, Bronchitis, C-reactive Protein Increased, Cough (4922581-1)
on Oct 03, 2005 Male from JAPAN , 67 years of age, weighting 143.3 lb, was treated with Zyloric. Directly after, patient experienced the unwanted or unexpected Zyloric side effects: aphthous stomatitis, aspartate aminotransferase decreased, blood creatinine increased, blood glucose increased, blood lactate dehydrogenase increased, blood urea increased, bronchitis, c-reactive protein increased, cough. Zyloric dosage: 100mg Per Day.
Associated medications used:
  • Amaryl (1mg Per Day)
  • Basen (.2mg Three Times Per Day)
  • Lasix (20mg Per Day)
  • Aldactone (25mg Per Day)
  • Diovan (80mg Twice Per Day)
  • Artist (2.5mg Twice Per Day)
  • Adalat (20mg Twice Per Day)
  • Loxonin (60mg Twice Per Day)
Patient was hospitalized.

Showing 1-25 of 66 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Zyloric Information

More About Zyloric

Side Effects reported to FDA: 66. View Zyloric Adverse Reports

Zyloric safety alerts: No

Reported deaths: 12

Reported hospitalizations: 39

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