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Lethargy (5)
Electrolyte Imbalance; Magnesium Low; Calcium Low (2)
Frequent Bowel Movements (2)
Hepatic Cirrhosis (2)
No Energy (2)
Agitation (1)
Dry Mouth (1)
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Zyprexa Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 10428 

Vaginal Haemorrhage (8449823-2)
on Jun 12, 2012 Female from JAPAN , 25 years of age, was treated with Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: vaginal haemorrhage. Zyprexa dosage: 20 Mg, Each Morning.

Hyperhidrosis, Neuroleptic Malignant Syndrome, Staring, Hospitalisation, Amnesia, Balance Disorder, Bladder Dysfunction (8449813-X)
Patient was taking Zyprexa. Patient felt the following Zyprexa side effects: hyperhidrosis, neuroleptic malignant syndrome, staring, hospitalisation, amnesia, balance disorder, bladder dysfunction on Jun 08, 2012 from UNITED STATES Additional patient health information: Male , weighting 209.0 lb, . Zyprexa dosage: Unk.
Multiple prescriptions taken:
  • Ativan (Unk)
  • Haldol (Unk)
  • Clozaril (Unk)
Patient was hospitalized.

Fatigue, Sedation, Overdose, Mental Disorder, Delirium, Dizziness (8449811-6)
Adverse event was reported on Jun 08, 2012 by a Female taking Zyprexa (Dosage: 20 Mg, Qd) was diagnosed with
  • schizophrenia
and. Location: FRANCE , 57 years of age, weighting 136.7 lb, After Zyprexa was administered, patient encountered several Zyprexa side effects: fatigue, sedation, overdose, mental disorder, delirium, dizziness. Patient was hospitalized.

Neuroleptic Malignant Syndrome, Eating Disorder Symptom, Catatonia (8443745-9)
on Jun 05, 2012 Female from UNITED STATES , 22 years of age, was diagnosed with
  • schizophrenia
and was treated with Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: neuroleptic malignant syndrome, eating disorder symptom, catatonia. Zyprexa dosage: Unk.
Associated medications used:
  • Invega Sustenna (234 Mg, Other)
  • Lorazepam
Patient was hospitalized.


(8443722-8)
on Jun 11, 2012 Female from FINLAND , 45 years of age, was treated with Zyprexa. . Zyprexa dosage: 1 Df, Unk.

Agitation (8443712-5)
Patient was taking Zyprexa. After Zyprexa was administered, patient encountered several Zyprexa side effects: agitation on Jun 07, 2012 from FRANCE Additional patient health information: Male , 54 years of age, was diagnosed with
  • agitation
and. Zyprexa dosage: 10 Mg, Unk. Patient was hospitalized.

Agranulocytosis (8443711-3)
Adverse event was reported on Jun 05, 2012 by a Female taking Zyprexa (Dosage: 10 Mg, Bid) was diagnosed with
  • psychotic disorder
and. Location: NETHERLANDS , weighting 185.2 lb, Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: agranulocytosis.
Associated medications used:
  • Lorazepam
  • Nitrazepam (5 Mg, Unk)
  • Paroxetine (10 Mg, Unk)
Patient was hospitalized.

Granulomatous Liver Disease, Asthenia, Sarcoidosis, Influenza Like Illness, Hepatic Enzyme Increased, Road Traffic Accident, Blood Triglycerides Increased, Hepatic Steatosis, Blood Cholesterol Increased (8443706-X)
on Jun 08, 2012 Female from UNITED STATES , weighting 138.9 lb, was treated with Zyprexa. Patient felt the following Zyprexa side effects: granulomatous liver disease, asthenia, sarcoidosis, influenza like illness, hepatic enzyme increased, road traffic accident, blood triglycerides increased, hepatic steatosis, blood cholesterol increased. Zyprexa dosage: Unk.
Multiple prescriptions taken:
  • Xanax (Unk)
Patient was hospitalized.

Product Quality Issue, No Adverse Event, Off Label Use (8442205-9)
on Feb 23, 2012 Female from UNITED STATES , weighting 125.0 lb, was diagnosed with
  • insomnia
  • depression
  • narcolepsy
and was treated with Zyprexa. After Zyprexa was administered, patient encountered several Zyprexa side effects: product quality issue, no adverse event, off label use. Zyprexa dosage: N/A.
Multiple concurrent drugs taken:
  • Zoloft
  • Daytrana (20 Mg, Unk)


Abnormal Behaviour (8439798-4)
Patient was taking Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: abnormal behaviour on Jun 11, 2012 from UNITED STATES Additional patient health information: Female , 45 years of age, . Zyprexa dosage: 5 Mg, Once A Dsay, Po. Patient was hospitalized.

Electrocardiogram Repolarisation Abnormality, Bradycardia, Atrioventricular Block (8439722-4)
Adverse event was reported on Jun 05, 2012 by a Male taking Zyprexa (Dosage: 5 Mg, Daily) . Location: FRANCE , 24 years of age, Patient felt the following Zyprexa side effects: electrocardiogram repolarisation abnormality, bradycardia, atrioventricular block.
Multiple prescriptions taken:
  • Abilify (30 Mg, Daily)
  • Lepticur (10 Mg, Daily)
  • Abilify (40 Mg, Daily)
  • Tercian (150 Mg, Daily)
  • Atarax (300 Mg, Daily)
  • Fluanxol (4 %, Unk)
Patient was hospitalized.

Psychotic Disorder, Dyspnoea (8439041-6)
on Jun 04, 2012 Female from UNITED STATES , 85 years of age, was treated with Zyprexa. After Zyprexa was administered, patient encountered several Zyprexa side effects: psychotic disorder, dyspnoea. Zyprexa dosage: 20 Mg, Unk. Patient was hospitalized.

Off Label Use, Convulsion (8439036-2)
on Jun 04, 2012 Female from UNITED STATES , child 7 years of age, was treated with Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: off label use, convulsion. Zyprexa dosage: N/A.
Associated medications used:
  • Intuniv
Patient was hospitalized.

Vision Blurred, Dysarthria, Influenza, Gait Disturbance, Weight Increased (8436329-X)
Patient was taking Zyprexa Relprevv. Patient felt the following Zyprexa side effects: vision blurred, dysarthria, influenza, gait disturbance, weight increased on Jun 01, 2012 from NEW ZEALAND Additional patient health information: Male , 25 years of age, . Zyprexa Relprevv dosage: 300 Mg, 2/m.

Injection Site Pain (8436062-4)
Adverse event was reported on Nov 29, 2011 by a Male taking Zyprexa (Dosage: N/A) was diagnosed with
  • mood swings
  • sleep disorder
  • priapism
and. Location: UNITED STATES , 42 years of age, weighting 186.1 lb, After Zyprexa was administered, patient encountered several Zyprexa side effects: injection site pain.
Multiple concurrent drugs taken:
  • Ativan
  • Zoladex (3.6 Once)
  • Seroquel
  • Lamictal


Serotonin Syndrome, Renal Failure Acute, Loss Of Consciousness, Rhabdomyolysis, Incorrect Dose Administered, Haemoglobin Decreased, Pneumonia Aspiration (8431678-3)
on Jun 04, 2012 Male from UNITED STATES , weighting 155.0 lb, was treated with Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: serotonin syndrome, renal failure acute, loss of consciousness, rhabdomyolysis, incorrect dose administered, haemoglobin decreased, pneumonia aspiration. Zyprexa dosage: N/A.
Associated medications used:
  • Diltiazem (Once Daily)
  • Nucynta Er (1 Per Day)
  • Topamax (100 Mg Once Daily)
  • Remeron (Once Daily)
Patient was hospitalized.

Hyponatraemia, Psychotic Disorder, Intestinal Obstruction, Agitation, Vomiting (8431663-1)
on May 31, 2012 Female from UNITED STATES , 59 years of age, was treated with Zyprexa Relprevv. Patient felt the following Zyprexa side effects: hyponatraemia, psychotic disorder, intestinal obstruction, agitation, vomiting. Zyprexa Relprevv dosage: 300 Mg, 2/w. Patient was hospitalized.

Blood Creatine Phosphokinase Increased, Neuroleptic Malignant Syndrome, Pyrexia, Off Label Use (8431662-X)
Patient was taking Zyprexa. After Zyprexa was administered, patient encountered several Zyprexa side effects: blood creatine phosphokinase increased, neuroleptic malignant syndrome, pyrexia, off label use on May 30, 2012 from JAPAN Additional patient health information: Male , 17 years of age, was diagnosed with
  • postictal psychosis
and. Zyprexa dosage: 20 Mg, Unk.
Multiple concurrent drugs taken:
  • Diazepam (10 Mg, Unk)
  • Valproate Sodium (800 Mg, Unk)
  • Levetiracetam (500 Mg, Unk)
  • Silece (4 Mg, Unk)
  • Tegretol (600 Mg, Unk)
  • Depakene (200 Mg, Unk)
  • Levetiracetam (1000 Mg, Unk)
  • Lendormin (0.25 Mg, Prn)
Patient was hospitalized.

Schizophrenia (8430290-X)
Adverse event was reported on May 30, 2012 by a Male taking Zyprexa Relprevv (Dosage: 150 Mg, Other) was diagnosed with
  • schizophrenia
and. Location: UNITED STATES , weighting 200.0 lb, Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: schizophrenia. Patient was hospitalized.

Aspiration, Gastric Dilatation, Respiratory Disorder (8430285-6)
on May 31, 2012 Female from JAPAN , 62 years of age, was diagnosed with
  • schizophrenia
and was treated with Zyprexa. Patient felt the following Zyprexa side effects: aspiration, gastric dilatation, respiratory disorder. Zyprexa dosage: Unk. Patient was hospitalized.

Weight Increased, Completed Suicide, Hospitalisation, Feeling Abnormal (8430284-4)
on May 31, 2012 Male from FINLAND , 30 years of age, was treated with Zyprexa. After Zyprexa was administered, patient encountered several Zyprexa side effects: weight increased, completed suicide, hospitalisation, feeling abnormal. Zyprexa dosage: N/A. Patient was hospitalized.

Myelodysplastic Syndrome, Parkinsonism (8430278-9)
Patient was taking Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: myelodysplastic syndrome, parkinsonism on May 30, 2012 from JAPAN Additional patient health information: Male , 62 years of age, . Zyprexa dosage: N/A.
Associated medications used:
  • Nitrazepam
  • Magnesium Oxide


Glycosylated Haemoglobin Increased, Large Intestine Carcinoma, Hyperglycaemia, Breast Cancer (8426098-1)
Adverse event was reported on May 29, 2012 by a Female taking Zyprexa (Dosage: 5 Mg, Qd) was diagnosed with
  • schizophrenia
and. Location: JAPAN , 68 years of age, Patient felt the following Zyprexa side effects: glycosylated haemoglobin increased, large intestine carcinoma, hyperglycaemia, breast cancer. Patient was hospitalized.

Suicidal Ideation, Gynaecomastia, Blood Testosterone Decreased (8426065-8)
on May 29, 2012 Male from GERMANY , 15 years of age, was diagnosed with
  • schizophrenia, catatonic type
and was treated with Zyprexa. After Zyprexa was administered, patient encountered several Zyprexa side effects: suicidal ideation, gynaecomastia, blood testosterone decreased. Zyprexa dosage: 15 Mg, Unk.

Disseminated Intravascular Coagulation, Blood Creatine Phosphokinase Increased, Diabetic Ketoacidosis, Renal Failure Acute, Acute Respiratory Failure (8419475-6)
on May 28, 2012 Male from JAPAN , 34 years of age, was diagnosed with
  • schizophrenia
and was treated with Zyprexa. Directly after, patient experienced the unwanted or unexpected Zyprexa side effects: disseminated intravascular coagulation, blood creatine phosphokinase increased, diabetic ketoacidosis, renal failure acute, acute respiratory failure. Zyprexa dosage: 20 Mg, Qd. Patient was hospitalized.

Showing 1-25 of 10428 

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Zyprexa Information

Alternative ZYPREXA Names:OLANZAPIN

Active Ingredient: OLANZAPIN

Zyprexa Dosage, Warnings, Usage.

Side Effects reported to FDA: 10428. View Zyprexa Adverse Reports

Zyprexa safety alerts: 2013 2010 2005 2004 2002

Reported deaths: 1562

Reported hospitalizations: 5207

Zyprexa (olanzapine): Use in Adolescents

Audience: Neuropsychiatric healthcare professionals

[Posted 01/29/2010] Lilly and FDA notified healthcare professionals of changes to the Prescribing Information for Zyprexa related to its indication for use in adolescents (ages 13-17) for treatment of schizophrenia and bipolar I disorder [manic or mixed episodes]. The revised labeling states that:

Section 1, Indications and Usage: When deciding among the alternative treatments available for adolescents, clinicians should consider the increased potential (in adolescents as compared with adults) for weight gain and hyperlipidemia. Clinicians should consider the potential long-term risks when prescribing to adolescents, and in many cases this may lead them to consider prescribing other drugs first in adolescents.

Section 17.14, Need for comprehensive Treatment Program in Pediatric Patients: Zyprexa is indicated as an integral part of a total treatment program for pediatric patients with schizophrenia and bipolar disorder that may include other measures (psychological, educational, social) for patients with the disorder. Effectiveness and safety of ZYPREXA have not been established in pediatric patients less than 13 years of age.

[01/04/2010 - Dear Healthcare Professional Letter - Lilly]
[12/2009 - Prescribing Information - Lilly]

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