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Metformin Agitation Side Effect Reports


The following Metformin Agitation side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Agitation, can occur, and what you can do about them.

A side effect could appear soon after you start Metformin or it might take time to develop.


Hypoglycaemic Coma, Tongue Biting, Metabolic Encephalopathy, Apallic Syndrome, Urinary Incontinence, Agitation, Accidental Overdose, Encephalitis

This Agitation side effect was reported by a health professional from FR. A 63-year-old patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus. The patient was prescribed Metformin (metformin) (dosage: 1500 Mg (500 Mg, 3 In 1 D)), which was started on Nov 15, 2013. Concurrently used drugs:
  • Atenolol (atenolol) (100 Mg, 1 D)
  • Amarel (glimepiride) (4 Mg, 1 D)
  • Onglyza (saxagliptin Hydrochloride) (5 Mg, 1 D)
  • Oflocet (ofloxacin) (400 Mg (200 Mg, 2 In 1 D))
  • Inexium (esomeprazole Magnesium) (esomeprazole Magnesium)
  • Lipanthyl (fenofibrate)
When starting to take Metformin (metformin) the consumer reported the following symptoms:
  • Hypoglycaemic Coma
  • Tongue Biting
  • Metabolic Encephalopathy
  • Apallic Syndrome
  • Urinary Incontinence
  • Agitation
  • Accidental Overdose
  • Encephalitis
The patient was hospitalized. These side effects may potentially be related to Metformin (metformin).
Agitation, Overdose

This Agitation Metformin side effect was reported by a physician from IT on Feb 25, 2014. A male , 71 years of age, was treated with Metformin. The patient presented the following health conditions:
  • Agitation
  • Overdose
. Metformin dosage: 2000 Mg Total. Additional drugs used at the same time:
  • Finasteride (15 Df Total)
  • Samyr (20 Df Total)
Agitation, Overdose

This is a Metformin side effect report of a 71-year-old patient (weight:NA) from IT, suffering from the following symptoms/conditions: NA, who was treated with Metformin (dosage:2000 Mg Total, start time: Dec 21, 2013), combined with:
  • Finasteride (15 Df Total)
  • Samyr /00882301/ (20 Df Total)
, and developed a serious reaction and a Agitation side effect. The patient presented with:
  • Agitation
  • Overdose
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Metformin treatment in patients suffering from NA, resulting in Agitation.
Chest Pain, Circulatory Collapse, Lactic Acidosis, Toxicity To Various Agents, Blood Glucose Increased, Pruritus, Hypophagia, Decreased Appetite, Agitation

A 70-year-old female patient (weight: NA) from IT with the following symptoms: type 2 diabetes mellitus started Metformin treatment (dosage: NA) on NS. Soon after starting Metformin treatment, the consumer experienced several side effects, including:
  • Chest Pain
  • Circulatory Collapse
  • Lactic Acidosis
  • Toxicity To Various Agents
  • Blood Glucose Increased
  • Pruritus
  • Hypophagia
  • Decreased Appetite
  • Agitation
. Concurrently used drugs:
  • Heparin (heparin)
  • Cetrizine (cetrizine)
  • Irebsartan (irebesartan)
  • Insulin (insulin)
  • Furosemide (furosemide)
The patient was hospitalized and became disabled. This finding indicates that some patients can be more vulnerable to developing Metformin side effects, such as Agitation.
Lactic Acidosis, Constipation, Dizziness, Vomiting, Unresponsive To Stimuli, Agitation, Blood Pressure Decreased, Heart Rate Increased, Haemodialysis

A patient from US was prescribed and started Metformin on Aug 07, 2013. Patient felt the following Metformin side effects: lactic acidosis, constipation, dizziness, vomiting, unresponsive to stimuli, agitation, blood pressure decreased, heart rate increased, haemodialysis Additional patient health information: male , 37 years of age, The consumer reported the following symptoms: . Metformin dosage: NA. Concurrently used drugs:
  • Lisinopril
  • Meetamucil
  • Colace
  • Valproic Acid
  • Paliperidone
  • Simvastatin
  • Aspirin
The patient was hospitalized.
Confusional State, Catatonia, Agitation, Aggression, Hallucination

This report suggests a potential Metformin Hcl Agitation side effect(s) that can have serious consequences. A 62-year-old patient from DE (weight:NA) was diagnosed with the following health condition(s): NA and used Metformin Hcl (dosage: NA) starting NS. Soon after starting Metformin Hcl the patient began experiencing various side effects, including:
  • Confusional State
  • Catatonia
  • Agitation
  • Aggression
  • Hallucination
Drugs used concurrently:
  • Acetaminophen
  • Ferrous Sulfate
  • Albuterol
  • Benztropine Mesylate
  • Budesonide
  • Docusate
  • Gemfibrozil
  • Glipizide
The patient was hospitalized. Although Metformin Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Agitation, may still occur.
Toxicity To Various Agents, Lactic Acidosis, Abdominal Pain, Vomiting, Confusional State, Dyspnoea, Moaning, Incoherent, Agitation

An adverse event was reported by a health professional on Jul 31, 2013 by a Female taking Metformin (dosage: Unk Ukn, Unk) . Location: US , 54 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Metformin side effects: toxicity to various agents, lactic acidosis, abdominal pain, vomiting, confusional state, dyspnoea, moaning, incoherent, agitation. Additional medications/treatments:
Associated medications used:
  • Enalapril (Unk Ukn, Unk)
  • Glimepiride (Unk Ukn, Unk)
  • Imipramine
  • Aspirin (Unk Ukn, Unk)
  • Ibuprofen (Unk Ukn, Unk)
The patient was hospitalized.
Metabolic Acidosis, Depressed Level Of Consciousness, Tachypnoea, Agitation, Hypotension, Hypothermia, Suicide Attempt, Intentional Overdose, Haemodialysis

This Agitation problem was reported by a health professional from US. A 56-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Metformin (metformin) (dosage: NA). The following drugs/medications were being taken at the same time:
  • Zolpidem (zolpidem)
When commencing Metformin (metformin), the patient experienced the following unwanted symptoms /side effects:
  • Metabolic Acidosis
  • Depressed Level Of Consciousness
  • Tachypnoea
  • Agitation
  • Hypotension
  • Hypothermia
  • Suicide Attempt
  • Intentional Overdose
  • Haemodialysis
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Agitation, may become evident only after a product is in use by the general population.
Abdominal Pain, Dizziness, Vomiting, Constipation, Unresponsive To Stimuli, Agitation, Blood Pressure Decreased, Heart Rate Increased, Respiratory Rate Increased

This is a Metformin (metformin) side effect report of a 37-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Metformin (metformin) (dosage: NA) starting NS. Concurrently used drugs:
  • Lisinopril (lisinopril)
  • Metamucil (plantago Ovata)
  • Colace
  • Valproic Acid (valproic Acid)
  • Paliperidone (paliperidone)
  • Simvastatin (simvastatin)
  • Aspirin (acetylsalicylic Acid)
Soon after that, the consumer experienced the following of symptoms:
  • Abdominal Pain
  • Dizziness
  • Vomiting
  • Constipation
  • Unresponsive To Stimuli
  • Agitation
  • Blood Pressure Decreased
  • Heart Rate Increased
  • Respiratory Rate Increased
The patient was hospitalized. This opens a possibility that Metformin (metformin) could cause Agitation and that some patients may be more susceptible.
Toxicity To Various Agents, Lactic Acidosis, Dizziness, Vomiting, Agitation, Unresponsive To Stimuli, Renal Failure, Constipation

This Agitation side effect was reported by a health professional from US on Jun 03, 2013. A patient from US , 37 years of age, was treated with Metformin. Directly after treatment started, patient experienced the unwanted or unexpected Metformin side effects: toxicity to various agents, lactic acidosis, dizziness, vomiting, agitation, unresponsive to stimuli, renal failure, constipation. Metformin dosage: 1000 Mg, Bid.
Associated medications used:
  • Lisinopril
  • Metamucil
  • Colace
  • Valproic Acid
  • Paliperidone
  • Simvastatin
  • Aspirin
The patient was hospitalized. These side effects may potentially be related to Metformin.
Lactic Acidosis, Respiratory Acidosis, Intentional Overdose, Suicide Attempt, Agitation, Metabolic Acidosis, Coma Scale Abnormal, Hypotension, Hypothermia

This Agitation side effect was reported by a health professional from CN. A 56-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Metformin (dosage: NA), which was started on NS. Concurrently used drugs:
  • Zolpidem
When starting to take Metformin the consumer reported the following symptoms:
  • Lactic Acidosis
  • Respiratory Acidosis
  • Intentional Overdose
  • Suicide Attempt
  • Agitation
  • Metabolic Acidosis
  • Coma Scale Abnormal
  • Hypotension
  • Hypothermia
The patient was hospitalized. These side effects may potentially be related to Metformin.
Intentional Overdose, Suicide Attempt, Memory Impairment, Vomiting, Confusional State, Agitation, Hypotension, Sinus Bradycardia, Respiratory Rate Increased

This Agitation Metformin side effect was reported by a physician from TR on Apr 26, 2013. A Female , 30 years of age, was treated with Metformin. The patient presented the following health conditions:
  • Intentional Overdose
  • Suicide Attempt
  • Memory Impairment
  • Vomiting
  • Confusional State
  • Agitation
  • Hypotension
  • Sinus Bradycardia
  • Respiratory Rate Increased
. Metformin dosage: NA. Additional drugs used at the same time: NA. The patient was hospitalized.
Hypoglycaemia, Pyrexia, Altered State Of Consciousness, Renal Failure, Benign Prostatic Hyperplasia, Hypertonic Bladder, Delirium, Agitation, Sleep Disorder

This is a Metformin Hydrochloride side effect report of a 85-year-old patient (weight:NA) from MA, suffering from the following symptoms/conditions: type 2 diabetes mellitus,hypertension, who was treated with Metformin Hydrochloride (dosage:2 Gram/day, start time: NS), combined with:
  • Amlodipine (10 Mg/day)
, and developed a serious reaction and a Agitation side effect. The patient presented with:
  • Hypoglycaemia
  • Pyrexia
  • Altered State Of Consciousness
  • Renal Failure
  • Benign Prostatic Hyperplasia
  • Hypertonic Bladder
  • Delirium
  • Agitation
  • Sleep Disorder
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Metformin Hydrochloride treatment in patients suffering from type 2 diabetes mellitus,hypertension, resulting in Agitation.
Ventricular Fibrillation, Anuria, Apnoea, Sedation, Agitation, Tachypnoea, Lactic Acidosis, Abdominal Pain, Vomiting

A 60-year-old patient (weight: NA) from DE with the following symptoms: NA started Metformin Hcl Tabs 500mg treatment (dosage: 100 Metformin 500mg/tab) on NS. Soon after starting Metformin Hcl Tabs 500mg treatment, the consumer experienced several side effects, including:
  • Ventricular Fibrillation
  • Anuria
  • Apnoea
  • Sedation
  • Agitation
  • Tachypnoea
  • Lactic Acidosis
  • Abdominal Pain
  • Vomiting
. Concurrently used drugs:
  • Glibenclamide (20 Glibenclamide 5mg Tab)
  • Motrin (Took 20 Ibuprofen 400mg/tab)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Metformin Hcl Tabs 500mg side effects, such as Agitation.
Lactic Acidosis, Intentional Overdose, Abdominal Pain, Agitation, Anuria, Apnoea, Sedation, Tachypnoea, Ventricular Fibrillation

A patient from GB was prescribed and started Metformin on Apr 24, 2013. After Metformin was administered, patient encountered several Metformin side effects: lactic acidosis, intentional overdose, abdominal pain, agitation, anuria, apnoea, sedation, tachypnoea, ventricular fibrillation Additional patient health information: male , 60 years of age, The consumer reported the following symptoms: . Metformin dosage: NA. Concurrently used drugs:
  • Glibenclamide
  • Motrin
The patient was hospitalized.
Intentional Overdose, Vomiting, Abdominal Pain, Tachypnoea, Agitation, Heart Rate Increased, Blood Glucose Increased, Apnoea, Ventricular Fibrillation

This report suggests a potential Metformin (metformin) Agitation side effect(s) that can have serious consequences. A 60-year-old patient from GB (weight:NA) was diagnosed with the following health condition(s): NA and used Metformin (metformin) (dosage: 100 Dosage Forms, Total) starting NS. Soon after starting Metformin (metformin) the patient began experiencing various side effects, including:
  • Intentional Overdose
  • Vomiting
  • Abdominal Pain
  • Tachypnoea
  • Agitation
  • Heart Rate Increased
  • Blood Glucose Increased
  • Apnoea
  • Ventricular Fibrillation
Drugs used concurrently:
  • Glibenclamide (20 Dosage Form, Total)
  • Motrin (ibuprofen) (20 Dosage Form, Total)
The patient was hospitalized. Although Metformin (metformin) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Agitation, may still occur.
Intentional Overdose, Toxicity To Various Agents, Agitation

An adverse event was reported by a physician on Oct 21, 2013 by a male taking Metformin (dosage: NA) was diagnosed with and. Location: IT , 60 years of age, patient began experiencing various side effects, including: Patient felt the following Metformin side effects: intentional overdose, toxicity to various agents, agitation. Additional medications/treatments:
Multiple prescriptions taken:
  • Depakin
  • Seroquel
  • Triatec
  • Lasix
  • Zyloric
  • Sinvacor
  • Seloken
  • Cardioaspirin
The patient was hospitalized.
Hypoglycaemia, Delirium, Agitation, Sleep Disorder, Cognitive Disorder

This Agitation problem was reported by a health professional from MA. A 85-year-old patient (weight: NA) was diagnosed with the following medical condition(s): type 2 diabetes mellitus,pyrexia,hypertension.On NS a consumer started treatment with Metformin (dosage: 2 G/day). The following drugs/medications were being taken at the same time:
  • Paracetamol (500 Mg, Tid)
  • Amlodipine (10 Mg/day)
  • Amoxicillin (1 G, Bid)
When commencing Metformin, the patient experienced the following unwanted symptoms /side effects:
  • Hypoglycaemia
  • Delirium
  • Agitation
  • Sleep Disorder
  • Cognitive Disorder
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Agitation, may become evident only after a product is in use by the general population.
Overdose, Lactic Acidosis, Apnoea, Ventricular Fibrillation, Abdominal Pain, Agitation, Somnolence, Body Temperature Decreased, Anuria

This is a Metformin side effect report of a 60-year-old patient (weight: NA) from GB. The patient developed the following symptoms/conditions: NA and was treated with Metformin (dosage: NA) starting NS. Concurrently used drugs:
  • Glibenclamide (20 Doses X 5 Mg Once)
  • Ibuprofen
Soon after that, the consumer experienced the following of symptoms:
  • Overdose
  • Lactic Acidosis
  • Apnoea
  • Ventricular Fibrillation
  • Abdominal Pain
  • Agitation
  • Somnolence
  • Body Temperature Decreased
  • Anuria
The patient was hospitalized. This opens a possibility that Metformin could cause Agitation and that some patients may be more susceptible.
Ventricular Fibrillation, Tachypnoea, Anuria, Agitation, Sedation, Apnoea, Lactic Acidosis, Vomiting, Abdominal Pain

This Agitation side effect was reported by a consumer or non-health professional from US on Oct 08, 2013. A patient from US , 60 years of age, was treated with Metformin. Patient felt the following Metformin side effects: ventricular fibrillation, tachypnoea, anuria, agitation, sedation, apnoea, lactic acidosis, vomiting, abdominal pain. Metformin dosage: 50000 Mg.
Multiple prescriptions taken:
  • Glibenclamide (20 Df)
  • Motrin (8000 Mg, Daily Dose)
The patient was hospitalized. These side effects may potentially be related to Metformin.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Metformin Agitation Causes and Reviews


Caring for someone who has Alzheimer's disease (AD) can be stressful and overwhelming. It's important to take care of yourself. Ask for and accept help.

Talk to the doctor. Find out what treatments might help control symptoms or address behavior problems. Find a support group. Others who have "been there" may be able to help and will understand.

If there are times of day that the person is less confused or more cooperative, take advantage of that in daily routines. Consider using adult day care or respite services. These offer a break with the peace of mind that the patient is being taken care of. Begin to plan for the future. This may include

  • Getting financial and legal documents in order
  • Looking into assisted living or nursing homes
  • Finding out what your health insurance and Medicare will cover

NIH: National Institute on Aging


Metformin Agitation Reviews

Sat, 12 Oct 2013

I have the same suspicion, i took glucophage for few months and had gout. I stoped it for 3 years and never had any symptoms. Last year i started glucophage again and got gout again in couple of months?! I also think there is a connection, probably to certain body types?!

Sat, 21 Apr 2012

Your diet is also something that will help you process the uric acid
and eliminate it from your body. Low-purine food choices include: green
vegetables, tomatoes, sugar, low-fat milk products, eggs, cheese,
olives, rice, pasta, grains, breads, fruits, chocolate, cereals, and
coffee.

Tue, 14 Dec 2010

I'm on Metformin for PCOS and have severe chronic diarrhoea. Along with Stomach pain, Nausea and tiredness. I take it twice a day and have been on it for 2 months now. Doctor yesterday told me to have a trial period without it for 2 weeks and see if I still have any. Up to now nothing.

Thu, 05 Aug 2010

Feeling sleepy, fatigue, and tiredall the time. My vision is also gone seriously blurred.

Wed, 11 Jan 2012

lower left lip numbness
physical lazyness
changes in mood
Metformin 3x500 a day

Thu, 07 Jul 2011

Feeling nervous

Tue, 26 Jan 2010

at what age should stop taking this drug?

Mon, 12 Mar 2012

MY POP STARTED ME ON 5OOMG OF MEDFORMIN AND THE SHORT TIM EXPERINCED, NSEUA. HDACHE'
AND SWEATING, MINOR ACHES ALSO, MY POP CALLED THIS PM AND CUT MYMEDFORMIN BK TO 1X
THE 2 I FEEL WAS TOO STRONG FOR ME.
IF THIS WORKS SHE ALSO GOING TO WEAN ME OFF THE INSULIN, NOW 40 UNITS, WAS UP TO 65 DID NOT FEEL RIGHT. MY #S WERE 169 EMPTY AND 2 HRS AFTER # 161, MAYBE THJERE IS HOPE!!
SHE WANTS ME TEST 4X AND CALL HER WITH THE RESULTS,,,,,,,,,

Sat, 28 May 2011

I have been taking Metformin 500 mg tablets, I have been taking for over a week 4 tablets a day 2 at night 2 in morning but have not been able to urinate properly, so I have stopped as I have small amounts of clotted blood come out my penis, has anyone ever had this happen to them ?

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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