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Metformin Fatigue Side Effects

Metformin Fatigue Side Effect Reports


The following Metformin Fatigue side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Fatigue, can occur, and what you can do about them.

A side effect could appear soon after you start Metformin or it might take time to develop.



Somnolence, Fatigue, Depressed Mood

This Fatigue side effect was reported by a consumer or non-health professional from US. A 17-year-old patient (weight:NA) experienced the following symptoms/conditions: glucose tolerance impaired,insulin resistance,overweight. The patient was prescribed Metformin (dosage: 1 Tablet), which was started on Jan 11, 2014. Concurrently used drugs: NA. When starting to take Metformin the consumer reported the following symptoms:
  • Somnolence
  • Fatigue
  • Depressed Mood
These side effects may potentially be related to Metformin.
Angioedema, Gastrointestinal Disorder, Depression, Fatigue, Headache, Erythema Marginatum

This Fatigue Metformin side effect was reported by a health professional from US on Feb 27, 2014. A Female , 24 years of age, was diagnosed with and was treated with Metformin. The patient presented the following health conditions:
  • Angioedema
  • Gastrointestinal Disorder
  • Depression
  • Fatigue
  • Headache
  • Erythema Marginatum
. Metformin dosage: NA. Additional drugs used at the same time:
  • Ethinylestradiol
  • Hydroxychloroquine
  • Levothyroxine Sodium
  • Gabapentin
  • Citalopram
  • Rabeprazole
  • Spironolactone
Gastrointestinal Disorder, Hereditary Angioedema, Fatigue, Depression, Erythema Marginatum, Off Label Use, Headache

This is a Metformin side effect report of a 24-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: polycystic ovaries, who was treated with Metformin (dosage:Unk, start time: NS), combined with:
  • Ethinylestradiol (Unk)
  • Spironolactone (Unk)
  • Hydrochloroquine (Unk)
  • Levothyroxine (Unk)
  • Gabapentin (Unk)
  • Citalopram (Unk)
  • Rabeprazole (Unk)
, and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Gastrointestinal Disorder
  • Hereditary Angioedema
  • Fatigue
  • Depression
  • Erythema Marginatum
  • Off Label Use
  • Headache
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Metformin treatment in female patients suffering from polycystic ovaries, resulting in Fatigue.

Mouth Haemorrhage, Vessel Puncture Site Bruise, Anaemia, Leukocytosis, Thrombocytopenia, Renal Impairment, Fatigue, Haematochezia, Overdose

A 83-year-old female patient (weight: NA) from DE with the following symptoms: NA started Metformin Hcl treatment (dosage: NA) on NS. Soon after starting Metformin Hcl treatment, the consumer experienced several side effects, including:
  • Mouth Haemorrhage
  • Vessel Puncture Site Bruise
  • Anaemia
  • Leukocytosis
  • Thrombocytopenia
  • Renal Impairment
  • Fatigue
  • Haematochezia
  • Overdose
. Concurrently used drugs:
  • Dabigatran Etexilate
  • Amiodarone
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Metformin Hcl side effects, such as Fatigue.
Abdominal Pain Upper, Diarrhoea, Myalgia, Blood Glucose Increased, Asthenia, Fatigue, Dyspnoea

A patient from US was prescribed and started Metformin on Oct 25, 2013. Patient felt the following Metformin side effects: abdominal pain upper, diarrhoea, myalgia, blood glucose increased, asthenia, fatigue, dyspnoea Additional patient health information: male , 56 years of age, weighting 289.0 lb, The consumer reported the following symptoms: . Metformin dosage: 1 Pill. Concurrently used drugs: NA.
Fatigue, Nausea, Vomiting, Diarrhoea, Decreased Appetite, Abdominal Pain, Pruritus, Jaundice, Liver Injury

This report suggests a potential Metformin Fatigue side effect(s) that can have serious consequences. A 78-year-old patient from IL (weight:NA) was diagnosed with the following health condition(s): type 2 diabetes mellitus and used Metformin (dosage: NA) starting NS. Soon after starting Metformin the patient began experiencing various side effects, including:
  • Fatigue
  • Nausea
  • Vomiting
  • Diarrhoea
  • Decreased Appetite
  • Abdominal Pain
  • Pruritus
  • Jaundice
  • Liver Injury
Drugs used concurrently:
  • Augmentin
  • Aspirin
  • Pravastatin
  • Amlodipine
  • Candesartan
  • Hydrochlorothiazide
The patient was hospitalized. Although Metformin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Cholestatic Liver Injury, Fatigue, Nausea, Vomiting, Diarrhoea, Decreased Appetite, Abdominal Pain, Pruritus, Jaundice

An adverse event was reported by a health professional on Sep 20, 2013 by a male taking Metformin (dosage: 850 Mg, Qd) was diagnosed with and. Location: IL , 78 years of age, weighting 180.8 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Metformin side effects: cholestatic liver injury, fatigue, nausea, vomiting, diarrhoea, decreased appetite, abdominal pain, pruritus, jaundice. Additional medications/treatments:
Associated medications used:
  • Augmentin
  • Aspirin (75 Mg/day)
  • Pravastatin (20 Mg/day)
  • Amlodipine (5 Mg/day)
  • Atenolol (100 Mg/day)
  • Candesartan (16 Mg/day)
  • Hydrochlorothiazide (12.5 Mg/day)
The patient was hospitalized.
Prostate Cancer, Retroperitoneal Lymphadenopathy, Metastases To Liver, Fatigue, Decreased Appetite, Dysgeusia, Weight Decreased, Nausea, Dizziness

This Fatigue problem was reported by a physician from US. A 53-year-old patient (weight: NA) was diagnosed with the following medical condition(s): diabetes mellitus,blood cholesterol increased,anxiety.On Dec 15, 2011 a consumer started treatment with Metformin (metformin) (dosage: 1000 Mg (500 Mg, 2 In 1 D), Oral). The following drugs/medications were being taken at the same time:
  • Lipitor (atorvastatin Calcium) (20 Mg (20 Mg, 1 In 1 D) Oral)
  • Zoloft (sertraline Hydrochloride) ((50 Mg, 1 D), Oral)
  • Taxotere (docetaxel)
  • Neulasta
  • Diovan (valsartan)
  • Toprol Xl (metoprolol Succinate) (100 Milligram) (metoprolol Succinate)
  • Aspirin (acetylsalicylic Acid)
  • Coreg (carvedilol)
When commencing Metformin (metformin), the patient experienced the following unwanted symptoms /side effects:
  • Prostate Cancer
  • Retroperitoneal Lymphadenopathy
  • Metastases To Liver
  • Fatigue
  • Decreased Appetite
  • Dysgeusia
  • Weight Decreased
  • Nausea
  • Dizziness
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Sexual Dysfunction, Rash, Dizziness, Abdominal Discomfort, Fatigue, Dyspepsia, Dry Mouth

This is a Metformin 1000mg side effect report of a 62-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: type 2 diabetes mellitus and was treated with Metformin 1000mg (dosage: Was Cut By 50% I.e. 500 Mg Twice A Day On 4/5/13) starting Apr 05, 2013. Concurrently used drugs:
  • Multivitamin
  • Aspirin
  • Fish Oil Concentrate
Soon after that, the consumer experienced the following of symptoms:
  • Sexual Dysfunction
  • Rash
  • Dizziness
  • Abdominal Discomfort
  • Fatigue
  • Dyspepsia
  • Dry Mouth
This opens a possibility that Metformin 1000mg could cause Fatigue and that some patients may be more susceptible.
Coma, Hypoglycaemia, Diarrhoea, Vomiting, Nausea, Fatigue, Muscular Weakness

This Fatigue side effect was reported by a consumer or non-health professional from CN on Aug 27, 2013. A patient from CN , 80 years of age, weighting 149.9 lb, was diagnosed with and was treated with Metformin Hcl. Directly after treatment started, patient experienced the unwanted or unexpected Metformin side effects: coma, hypoglycaemia, diarrhoea, vomiting, nausea, fatigue, muscular weakness. Metformin Hcl dosage: NA.
Associated medications used:
  • Gliclazide
  • Felodipine
  • Valsartan
These side effects may potentially be related to Metformin Hcl.
Polycythaemia, Fatigue, Laziness, Skin Discolouration

This Fatigue side effect was reported by a physician from DE. A patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Metformin (metformin) (dosage: NA), which was started on NS. Concurrently used drugs: NA. When starting to take Metformin (metformin) the consumer reported the following symptoms:
  • Polycythaemia
  • Fatigue
  • Laziness
  • Skin Discolouration
These side effects may potentially be related to Metformin (metformin).
Fatigue, Neuropathy Peripheral

This Fatigue Metformin Hcl side effect was reported by a consumer or non-health professional from US on Aug 14, 2013. A Female , 55 years of age, weighting 145.0 lb, was diagnosed with and was treated with Metformin Hcl. The patient presented the following health conditions:
  • Fatigue
  • Neuropathy Peripheral
. Metformin Hcl dosage: 500 2 Tablets Daily By Mouth. Additional drugs used at the same time: NA.
Liver Disorder, Feeling Cold, Thinking Abnormal, Fatigue, Hypersomnia, Crying, Suicidal Ideation, Nausea, Injection Site Pruritus

This is a Metformin side effect report of a 63-year-old female patient (weight:NA) from NL, suffering from the following symptoms/conditions: type 2 diabetes mellitus, who was treated with Metformin (dosage:4 Dosis, start time: Mar 27, 2013), combined with:
  • Tolbutamide (4 Dosis)
  • Levemir
  • Novorapid
  • Enalapril Maleate (1 Tablet 5 Mg)
  • Omeprazole (1 Tablet 20 Mg)
, and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Liver Disorder
  • Feeling Cold
  • Thinking Abnormal
  • Fatigue
  • Hypersomnia
  • Crying
  • Suicidal Ideation
  • Nausea
  • Injection Site Pruritus
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Metformin treatment in female patients suffering from type 2 diabetes mellitus, resulting in Fatigue.
Product Substitution Issue, Diarrhoea, Abdominal Distension, Nausea, Dizziness, Fatigue, Muscle Spasms

A 29-year-old female patient (weight: NA) from US with the following symptoms: insulin resistance,polycystic ovaries started Metformin Hcl Er Tabs 500mg treatment (dosage: 2 Pills Twice Daily (morning And Evening) By Mouth) on Jun 19, 2013. Soon after starting Metformin Hcl Er Tabs 500mg treatment, the consumer experienced several side effects, including:
  • Product Substitution Issue
  • Diarrhoea
  • Abdominal Distension
  • Nausea
  • Dizziness
  • Fatigue
  • Muscle Spasms
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Metformin Hcl Er Tabs 500mg side effects, such as Fatigue.
Fatigue, Vomiting, Lactic Acidosis, Renal Failure Acute

A patient from SE was prescribed and started Metformin on Jul 18, 2013. After Metformin was administered, patient encountered several Metformin side effects: fatigue, vomiting, lactic acidosis, renal failure acute Additional patient health information: male , 68 years of age, The consumer reported the following symptoms: . Metformin dosage: NA. Concurrently used drugs: NA.
Shock, Toxicity To Various Agents, Back Pain, Fatigue, Loss Of Consciousness, Dyspnoea, Blood Pressure Increased, Nausea, Vomiting

This report suggests a potential Metformin Hydrochloride Fatigue side effect(s) that can have serious consequences. A 66-year-old patient from SE (weight:NA) was diagnosed with the following health condition(s): NA and used Metformin Hydrochloride (dosage: NA) starting NS. Soon after starting Metformin Hydrochloride the patient began experiencing various side effects, including:
  • Shock
  • Toxicity To Various Agents
  • Back Pain
  • Fatigue
  • Loss Of Consciousness
  • Dyspnoea
  • Blood Pressure Increased
  • Nausea
  • Vomiting
Drugs used concurrently:NA. The patient was hospitalized. Although Metformin Hydrochloride demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Shock, Dyspnoea, Back Pain, Fatigue, Blood Pressure Decreased, Loss Of Consciousness, Vascular Resistance Systemic Decreased, Respiratory Failure, Oliguria

An adverse event was reported by a health professional on Jun 20, 2013 by a male taking Metformin (dosage: 1000 Mg, Tid) . Location: SE , 66 years of age, patient began experiencing various side effects, including: Patient felt the following Metformin side effects: shock, dyspnoea, back pain, fatigue, blood pressure decreased, loss of consciousness, vascular resistance systemic decreased, respiratory failure, oliguria. Additional medications/treatments: The patient was hospitalized.
Dyspnoea, Back Pain, Blood Pressure Increased, Fatigue, Nausea, Vomiting, Blood Pressure Decreased, Loss Of Consciousness, Vascular Resistance Systemic Decreased

This Fatigue problem was reported by a health professional from SE. A 66-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Metformin (dosage: 3000 Mg (1000 Mg,3 In 1 D)). The following drugs/medications were being taken at the same time:
  • Allopurinol (allopurinol)
When commencing Metformin, the patient experienced the following unwanted symptoms /side effects:
  • Dyspnoea
  • Back Pain
  • Blood Pressure Increased
  • Fatigue
  • Nausea
  • Vomiting
  • Blood Pressure Decreased
  • Loss Of Consciousness
  • Vascular Resistance Systemic Decreased
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Fatigue, Muscular Weakness, Pharyngeal Oedema, Musculoskeletal Stiffness, Dry Mouth, Dysgeusia, Abdominal Pain Upper, Diarrhoea, Hypoaesthesia Oral

This is a Metformin Hcl side effect report of a female patient (weight: NA) from US. The patient developed the following symptoms/conditions: diabetes mellitus and was treated with Metformin Hcl (dosage: 1 Tab) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Fatigue
  • Muscular Weakness
  • Pharyngeal Oedema
  • Musculoskeletal Stiffness
  • Dry Mouth
  • Dysgeusia
  • Abdominal Pain Upper
  • Diarrhoea
  • Hypoaesthesia Oral
This opens a possibility that Metformin Hcl could cause Fatigue and that some female patients may be more susceptible.
Rash Erythematous, Blister, Pruritus, Rash Pruritic, Abdominal Distension, Nausea, Fatigue

This Fatigue side effect was reported by a consumer or non-health professional from US on May 06, 2013. A female patient from US , 58 years of age, weighting 198.0 lb, was diagnosed with and was treated with Metformin Hydrochloride. Patient felt the following Metformin side effects: rash erythematous, blister, pruritus, rash pruritic, abdominal distension, nausea, fatigue. Metformin Hydrochloride dosage: NA. These side effects may potentially be related to Metformin Hydrochloride.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Metformin Fatigue Causes and Reviews


Everyone feels tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your Fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to Fatigue. These include

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme Fatigue is chronic Fatigue syndrome (CFS). This Fatigue is not the kind of tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging


Metformin Fatigue Reviews

Thu, 05 Aug 2010

Feeling sleepy, Fatigue, and tiredall the time. My vision is also gone seriously blurred.

Tue, 27 Apr 2010
Fatigue severe pain down left arm dizziness shortness of breath palputations and shere lack of get up and go
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Metformin Side Effects

Lactic Acidosis (2533)
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Diarrhoea (990)
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Metformin Common Side Effects

If you experienced any harmful or unwanted effects of Mucinex, please share your experience. This could help to raise awareness about Mucinex side effects, identify uknown risks and inform health professionals and patients taking Mucinex.

Examples: headache, dizziness

The most commonly reported Metformin side effects (click to view or check a box to report):

Lactic Acidosis (2533)
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Diarrhoea (990)
Vomiting (734)
Blood Glucose Increased (635)
Hypotension (588)
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Hypoglycaemia (554)
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Metabolic Acidosis (488)
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Renal Failure (366)
Cardiac Arrest (346)
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