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Metformin Side Effects List

Common Metformin Side Effects


The following Metformin Side Effects were reported by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers) and manufacturers.

It is important to know potential risks posed by drugs and health products. Staying informed can help you make right decisions and stay healthy.

You can read detailed reports by clicking on a side effect.




Abasia 14 reports0.04%
Abdominal Discomfort 153 reports0.49%
Abdominal Distension 71 reports0.23%
Abdominal Pain 385 reports1.23%
Abdominal Pain Lower 20 reports0.06%
Abdominal Pain Upper 177 reports0.56%
Abdominal Tenderness 21 reports0.07%
Abnormal Behaviour 18 reports0.06%
Abortion Induced 14 reports0.04%
Abortion Spontaneous 28 reports0.09%
Accidental Overdose 23 reports0.07%
Acidosis 115 reports0.37%
Acute Hepatic Failure 16 reports0.05%
Acute Myocardial Infarction 40 reports0.13%
Acute Prerenal Failure 18 reports0.06%
Acute Respiratory Distress Syndrome 51 reports0.16%
Adverse Event 17 reports0.05%
Aggression 20 reports0.06%
Agitation 148 reports0.47%
Alanine Aminotransferase Increased 101 reports0.32%
Alcohol Use 30 reports0.10%
Alopecia 67 reports0.21%
Altered State Of Consciousness 26 reports0.08%
Amnesia 38 reports0.12%
Amylase Increased 68 reports0.22%
Anaemia 100 reports0.32%
Anaphylactic Shock 17 reports0.05%
Angina Pectoris 21 reports0.07%
Angioedema 39 reports0.12%
Anhedonia 13 reports0.04%
Anion Gap Increased 33 reports0.11%
Anorexia 45 reports0.14%
Anuria 106 reports0.34%
Anxiety 67 reports0.21%
Aortic Stenosis 14 reports0.04%
Aphasia 17 reports0.05%
Apnoea 29 reports0.09%
Arrhythmia 28 reports0.09%
Arthralgia 55 reports0.18%
Arthropathy 18 reports0.06%
Ascites 17 reports0.05%
Aspartate Aminotransferase Increased 79 reports0.25%
Asthenia 233 reports0.74%
Asthma 20 reports0.06%
Atrial Fibrillation 85 reports0.27%
Atrioventricular Block Complete 22 reports0.07%
Azotaemia 22 reports0.07%
Back Pain 87 reports0.28%
Balance Disorder 28 reports0.09%
Bladder Cancer 31 reports0.10%
Blister 27 reports0.09%
Blood Alkaline Phosphatase Increased 18 reports0.06%
Blood Bicarbonate Decreased 23 reports0.07%
Blood Bilirubin Increased 28 reports0.09%
Blood Chloride Decreased 17 reports0.05%
Blood Cholesterol Increased 26 reports0.08%
Blood Creatine Increased 16 reports0.05%
Blood Creatine Phosphokinase Increased 47 reports0.15%
Blood Creatinine Increased 235 reports0.75%
Blood Glucose Abnormal 39 reports0.12%
Blood Glucose Decreased 163 reports0.52%
Blood Glucose Fluctuation 39 reports0.12%
Blood Glucose Increased 635 reports2.03%
Blood Lactate Dehydrogenase Increased 18 reports0.06%
Blood Lactic Acid Increased 100 reports0.32%
Blood Ph Decreased 24 reports0.08%
Blood Potassium Decreased 19 reports0.06%
Blood Potassium Increased 84 reports0.27%
Blood Pressure Decreased 119 reports0.38%
Blood Pressure Diastolic Decreased 26 reports0.08%
Blood Pressure Immeasurable 13 reports0.04%
Blood Pressure Increased 92 reports0.29%
Blood Pressure Systolic Increased 23 reports0.07%
Blood Sodium Decreased 47 reports0.15%
Blood Sodium Increased 22 reports0.07%
Blood Triglycerides Increased 16 reports0.05%
Blood Urea Increased 61 reports0.19%
Blood Urine Present 18 reports0.06%
Body Temperature Decreased 87 reports0.28%
Bradycardia 117 reports0.37%
Bronchitis 19 reports0.06%
Bundle Branch Block Right 19 reports0.06%
Burning Sensation 24 reports0.08%
C-reactive Protein Increased 20 reports0.06%
Caesarean Section 25 reports0.08%
Cardiac Arrest 346 reports1.10%
Cardiac Disorder 45 reports0.14%
Cardiac Failure 60 reports0.19%
Cardiac Failure Congestive 113 reports0.36%
Cardio-respiratory Arrest 78 reports0.25%
Cardiogenic Shock 26 reports0.08%
Cardiomyopathy 15 reports0.05%
Cardiopulmonary Failure 14 reports0.04%
Cardiovascular Disorder 40 reports0.13%
Cellulitis 28 reports0.09%
Cerebral Infarction 21 reports0.07%
Cerebrovascular Accident 112 reports0.36%
Chest Discomfort 47 reports0.15%
Chest Pain 116 reports0.37%
Chills 36 reports0.11%
Cholecystitis Chronic 37 reports0.12%
Cholelithiasis 41 reports0.13%
Cholestasis 26 reports0.08%
Chromaturia 18 reports0.06%
Chronic Obstructive Pulmonary Disease 24 reports0.08%
Circulatory Collapse 77 reports0.25%
Coagulopathy 26 reports0.08%
Cognitive Disorder 19 reports0.06%
Colitis 17 reports0.05%
Coma 102 reports0.33%
Coma Scale Abnormal 31 reports0.10%
Compartment Syndrome 16 reports0.05%
Completed Suicide 515 reports1.64%
Condition Aggravated 82 reports0.26%
Confusional State 213 reports0.68%
Constipation 90 reports0.29%
Continuous Haemodiafiltration 157 reports0.50%
Convulsion 79 reports0.25%
Coronary Artery Disease 62 reports0.20%
Coronary Artery Occlusion 18 reports0.06%
Cough 61 reports0.19%
Cyanosis 17 reports0.05%
Cytolytic Hepatitis 13 reports0.04%
Death 109 reports0.35%
Decreased Appetite 183 reports0.58%
Deep Vein Thrombosis 42 reports0.13%
Dehydration 375 reports1.20%
Delirium 25 reports0.08%
Depressed Level Of Consciousness 101 reports0.32%
Depression 74 reports0.24%
Diabetes Mellitus 66 reports0.21%
Diabetes Mellitus Inadequate Control 145 reports0.46%
Diabetic Ketoacidosis 28 reports0.09%
Diabetic Nephropathy 25 reports0.08%
Diabetic Neuropathy 13 reports0.04%
Dialysis 96 reports0.31%
Diarrhoea 990 reports3.16%
Discomfort 17 reports0.05%
Disorientation 68 reports0.22%
Disseminated Intravascular Coagulation 20 reports0.06%
Dizziness 259 reports0.83%
Dry Mouth 19 reports0.06%
Duodenal Ulcer 18 reports0.06%
Dysarthria 77 reports0.25%
Dysgeusia 46 reports0.15%
Dyspepsia 52 reports0.17%
Dysphagia 36 reports0.11%
Dyspnoea 333 reports1.06%
Dyspnoea Exertional 19 reports0.06%
Dysuria 16 reports0.05%
Electromechanical Dissociation 20 reports0.06%
Emotional Distress 29 reports0.09%
Encephalopathy 33 reports0.11%
Eosinophilia 13 reports0.04%
Epistaxis 23 reports0.07%
Eructation 17 reports0.05%
Erythema 58 reports0.18%
Exposure During Pregnancy 14 reports0.04%
Exposure Via Ingestion 112 reports0.36%
Faecal Incontinence 19 reports0.06%
Faeces Discoloured 13 reports0.04%
Fall 149 reports0.48%
Fatigue 212 reports0.68%
Fear 20 reports0.06%
Febrile Neutropenia 14 reports0.04%
Feeling Abnormal 86 reports0.27%
Feeling Cold 16 reports0.05%
Feeling Hot 41 reports0.13%
Flatulence 49 reports0.16%
Fluid Retention 20 reports0.06%
Flushing 54 reports0.17%
Gait Disturbance 71 reports0.23%
Gallbladder Disorder 36 reports0.11%
Gamma-glutamyltransferase Increased 39 reports0.12%
Gastric Ulcer 19 reports0.06%
Gastritis 33 reports0.11%
Gastroenteritis 76 reports0.24%
Gastrointestinal Disorder 74 reports0.24%
Gastrointestinal Haemorrhage 30 reports0.10%
Gastrointestinal Stoma Complication 14 reports0.04%
Gastrooesophageal Reflux Disease 33 reports0.11%
Glasgow Coma Scale Abnormal 16 reports0.05%
Glomerular Filtration Rate Decreased 30 reports0.10%
Glycosylated Haemoglobin Increased 109 reports0.35%
Gout 15 reports0.05%
Grand Mal Convulsion 15 reports0.05%
Haematemesis 38 reports0.12%
Haematochezia 15 reports0.05%
Haematocrit Decreased 16 reports0.05%
Haematuria 17 reports0.05%
Haemodialysis 566 reports1.81%
Haemodynamic Instability 77 reports0.25%
Haemoglobin Decreased 67 reports0.21%
Haemolytic Anaemia 31 reports0.10%
Haemorrhage 22 reports0.07%
Hallucination 34 reports0.11%
Hallucination, Visual 15 reports0.05%
Headache 177 reports0.56%
Heart Rate Decreased 27 reports0.09%
Heart Rate Increased 92 reports0.29%
Hemiparesis 19 reports0.06%
Hepatic Cirrhosis 14 reports0.04%
Hepatic Enzyme Increased 28 reports0.09%
Hepatic Failure 76 reports0.24%
Hepatic Function Abnormal 23 reports0.07%
Hepatic Steatosis 46 reports0.15%
Hepatitis 43 reports0.14%
Hepatitis Acute 41 reports0.13%
Hepatitis Cholestatic 24 reports0.08%
Hepatomegaly 13 reports0.04%
Hepatotoxicity 72 reports0.23%
Hot Flush 13 reports0.04%
Hyperglycaemia 99 reports0.32%
Hyperhidrosis 81 reports0.26%
Hyperkalaemia 276 reports0.88%
Hyperlactacidaemia 26 reports0.08%
Hyperlipidaemia 13 reports0.04%
Hypersensitivity 58 reports0.18%
Hypertension 120 reports0.38%
Hyperventilation 28 reports0.09%
Hypoaesthesia 37 reports0.12%
Hypocalcaemia 29 reports0.09%
Hypoglycaemia 554 reports1.77%
Hypoglycaemic Coma 68 reports0.22%
Hypokalaemia 39 reports0.12%
Hypomagnesaemia 31 reports0.10%
Hyponatraemia 26 reports0.08%
Hypophagia 39 reports0.12%
Hypotension 588 reports1.88%
Hypothermia 179 reports0.57%
Hypothyroidism 13 reports0.04%
Hypovolaemia 31 reports0.10%
Hypoxia 30 reports0.10%
Incorrect Dose Administered 53 reports0.17%
Infection 47 reports0.15%
Influenza 20 reports0.06%
Influenza Like Illness 27 reports0.09%
Injection Site Pain 22 reports0.07%
Injury 47 reports0.15%
Insomnia 43 reports0.14%
Intentional Overdose 229 reports0.73%
International Normalised Ratio Increased 30 reports0.10%
Intra-uterine Death 32 reports0.10%
Irritability 23 reports0.07%
Ischaemic Stroke 13 reports0.04%
Jaundice 60 reports0.19%
Joint Swelling 25 reports0.08%
Ketoacidosis 16 reports0.05%
Laboratory Test Abnormal 22 reports0.07%
Lactic Acidosis 2533 reports8.08%
Left Ventricular Failure 16 reports0.05%
Lethargy 101 reports0.32%
Leukocytoclastic Vasculitis 23 reports0.07%
Leukocytosis 32 reports0.10%
Lip Swelling 20 reports0.06%
Lipase Increased 15 reports0.05%
Liver Disorder 30 reports0.10%
Liver Function Test Abnormal 42 reports0.13%
Liver Injury 45 reports0.14%
Local Swelling 29 reports0.09%
Loss Of Consciousness 143 reports0.46%
Lower Respiratory Tract Infection 20 reports0.06%
Lung Disorder 14 reports0.04%
Macular Oedema 18 reports0.06%
Malaise 311 reports0.99%
Maternal Exposure During Pregnancy 32 reports0.10%
Melaena 23 reports0.07%
Memory Impairment 40 reports0.13%
Mental Disorder 23 reports0.07%
Mental Impairment 15 reports0.05%
Mental Status Changes 45 reports0.14%
Metabolic Acidosis 488 reports1.56%
Migraine 17 reports0.05%
Multi-organ Failure 153 reports0.49%
Muscle Spasms 77 reports0.25%
Muscular Weakness 48 reports0.15%
Musculoskeletal Pain 14 reports0.04%
Myalgia 95 reports0.30%
Myocardial Infarction 207 reports0.66%
Myocardial Ischaemia 21 reports0.07%
Myoclonus 21 reports0.07%
Nasopharyngitis 15 reports0.05%
Nausea 587 reports1.87%
Nephrolithiasis 22 reports0.07%
Nervous System Disorder 15 reports0.05%
Nervousness 13 reports0.04%
Neuropathy Peripheral 25 reports0.08%
Neutropenia 20 reports0.06%
Neutrophil Count Increased 20 reports0.06%
No Therapeutic Response 19 reports0.06%
Oedema 25 reports0.08%
Oedema Peripheral 98 reports0.31%
Off Label Use 53 reports0.17%
Oliguria 42 reports0.13%
Oropharyngeal Pain 17 reports0.05%
Overdose 258 reports0.82%
Oxygen Saturation Decreased 14 reports0.04%
Pain 161 reports0.51%
Pain In Extremity 72 reports0.23%
Pallor 29 reports0.09%
Palpitations 43 reports0.14%
Pancreatic Carcinoma 23 reports0.07%
Pancreatitis 137 reports0.44%
Pancreatitis Acute 175 reports0.56%
Pancreatitis Chronic 25 reports0.08%
Pancytopenia 14 reports0.04%
Panic Attack 14 reports0.04%
Paraesthesia 61 reports0.19%
Platelet Count Decreased 26 reports0.08%
Pleural Effusion 20 reports0.06%
Pneumonia 126 reports0.40%
Pneumonia Aspiration 18 reports0.06%
Poisoning 125 reports0.40%
Pollakiuria 14 reports0.04%
Pregnancy 57 reports0.18%
Product Odour Abnormal 34 reports0.11%
Product Quality Issue 81 reports0.26%
Product Substitution Issue 98 reports0.31%
Proteinuria 25 reports0.08%
Pruritus 113 reports0.36%
Psoriasis 22 reports0.07%
Psychomotor Hyperactivity 19 reports0.06%
Pulmonary Congestion 13 reports0.04%
Pulmonary Embolism 47 reports0.15%
Pulmonary Oedema 62 reports0.20%
Pulseless Electrical Activity 16 reports0.05%
Purpura 13 reports0.04%
Pyelonephritis 15 reports0.05%
Pyrexia 97 reports0.31%
Rash 104 reports0.33%
Rash Erythematous 16 reports0.05%
Rash Pruritic 17 reports0.05%
Rectal Haemorrhage 28 reports0.09%
Renal Cyst 13 reports0.04%
Renal Disorder 47 reports0.15%
Renal Failure 366 reports1.17%
Renal Failure Acute 1526 reports4.87%
Renal Failure Chronic 29 reports0.09%
Renal Impairment 256 reports0.82%
Renal Injury 25 reports0.08%
Renal Tubular Acidosis 22 reports0.07%
Respiratory Arrest 53 reports0.17%
Respiratory Disorder 20 reports0.06%
Respiratory Distress 42 reports0.13%
Respiratory Failure 82 reports0.26%
Respiratory Rate Increased 36 reports0.11%
Resuscitation 14 reports0.04%
Rhabdomyolysis 68 reports0.22%
Sepsis 106 reports0.34%
Septic Shock 35 reports0.11%
Shock 159 reports0.51%
Sinus Tachycardia 13 reports0.04%
Skin Discolouration 17 reports0.05%
Skin Exfoliation 13 reports0.04%
Skin Ulcer 13 reports0.04%
Sleep Disorder 17 reports0.05%
Somnolence 149 reports0.48%
Sopor 16 reports0.05%
Speech Disorder 19 reports0.06%
Stomach Discomfort 13 reports0.04%
Stomatitis 20 reports0.06%
Stress 33 reports0.11%
Sudden Death 21 reports0.07%
Suicidal Ideation 29 reports0.09%
Suicide Attempt 227 reports0.72%
Swelling 29 reports0.09%
Swelling Face 24 reports0.08%
Swollen Tongue 22 reports0.07%
Syncope 75 reports0.24%
Tachycardia 74 reports0.24%
Tachypnoea 65 reports0.21%
Thrombocytopenia 26 reports0.08%
Thrombosis 13 reports0.04%
Tooth Abscess 14 reports0.04%
Toxic Epidermal Necrolysis 15 reports0.05%
Toxicity To Various Agents 287 reports0.92%
Transaminases Increased 40 reports0.13%
Transient Ischaemic Attack 20 reports0.06%
Treatment Noncompliance 30 reports0.10%
Tremor 68 reports0.22%
Tubulointerstitial Nephritis 22 reports0.07%
Type 2 Diabetes Mellitus 13 reports0.04%
Unevaluable Event 24 reports0.08%
Unresponsive To Stimuli 39 reports0.12%
Urinary Tract Infection 58 reports0.18%
Urosepsis 14 reports0.04%
Urticaria 64 reports0.20%
Vasculitis 15 reports0.05%
Ventricular Fibrillation 24 reports0.08%
Ventricular Tachycardia 23 reports0.07%
Vertigo 36 reports0.11%
Vision Blurred 50 reports0.16%
Visual Acuity Reduced 16 reports0.05%
Visual Impairment 24 reports0.08%
Vitamin B12 Deficiency 36 reports0.11%
Vomiting 734 reports2.34%
Weight Decreased 196 reports0.63%
Weight Increased 100 reports0.32%
Wheezing 13 reports0.04%
White Blood Cell Count Increased 35 reports0.11%

Displaying 400 Metformin side effects


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