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Methadone Fatigue Side Effects

Methadone Fatigue Side Effect Reports


The following Methadone Fatigue side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Fatigue, can occur, and what you can do about them.

A side effect could appear soon after you start Methadone or it might take time to develop.



Acute Myocardial Infarction, Hypoxia, Somnolence, Arthralgia, Fall, Dizziness, Fatigue

This Fatigue side effect was reported by a consumer or non-health professional from US. A female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methadone (dosage: 10 Mg, Bid), which was started on Feb 22, 2012. Concurrently used drugs: NA. When starting to take Methadone the consumer reported the following symptoms:
  • Acute Myocardial Infarction
  • Hypoxia
  • Somnolence
  • Arthralgia
  • Fall
  • Dizziness
  • Fatigue
The patient was hospitalized. These side effects may potentially be related to Methadone.
Aggression, Incoherent, Dysstasia, Confusional State, Fatigue

This Fatigue Methadone side effect was reported by a health professional from GB on Jan 04, 2013. A Patient , 26 years of age, weighting 146.0 lb, was diagnosed with and was treated with Methadone. The patient presented the following health conditions:
  • Aggression
  • Incoherent
  • Dysstasia
  • Confusional State
  • Fatigue
. Methadone dosage: 100 Ml, Unk. Additional drugs used at the same time:
  • Diazepam (30 Mg, Unk)
  • Zolpidem Tartrate
Fatigue, Insomnia, Nightmare, Dyspnoea, Palpitations, Sneezing, Depression, Alopecia, Visual Impairment

This is a Methadone side effect report of a 54-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: migraine, who was treated with Methadone (dosage:NA, start time: 199911), combined with: NA., and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Fatigue
  • Insomnia
  • Nightmare
  • Dyspnoea
  • Palpitations
  • Sneezing
  • Depression
  • Alopecia
  • Visual Impairment
which developed after the beginning of treatment. The patient was hospitalized and became disabled. This side effect report can indicate a possible existence of increased vulnerability to Methadone treatment in female patients suffering from migraine, resulting in Fatigue.

Laceration, Dry Mouth, Rash Pruritic, Dysgeusia, Buccal Mucosal Roughening, Fatigue, Skin Chapped, Anger

A patient (weight: NA) from with the following symptoms: NA started Methadone Hcl treatment (dosage: NA) on Jan 28, 2012. Soon after starting Methadone Hcl treatment, the consumer experienced several side effects, including:
  • Laceration
  • Dry Mouth
  • Rash Pruritic
  • Dysgeusia
  • Buccal Mucosal Roughening
  • Fatigue
  • Skin Chapped
  • Anger
. Concurrently used drugs:
  • Peg-intron
  • Celexa
  • Tamazapam
  • Incivek
  • Ribavirin
This finding indicates that some patients can be more vulnerable to developing Methadone Hcl side effects, such as Fatigue.
Fatigue, Somnolence, Asthenia

A patient from UNITED STATES was prescribed and started Methadone Hcl on May 15, 2012. Patient felt the following Methadone side effects: fatigue, somnolence, asthenia Additional patient health information: male , 60 years of age, The consumer reported the following symptoms: was diagnosed with and. Methadone Hcl dosage: 80 Mg. Concurrently used drugs:
  • Opana
Haemorrhoids, Portal Hypertension, Hepatitis C, Fatigue, Hepatic Cirrhosis, Liver Disorder, Nasopharyngitis, Activities Of Daily Living Impaired, Renal Disorder

This report suggests a potential Methadone Hcl Fatigue side effect(s) that can have serious consequences. A 59-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): pain,sleep disorder and used Methadone Hcl (dosage: NA) starting Jan 01, 2006. Soon after starting Methadone Hcl the patient began experiencing various side effects, including:
  • Haemorrhoids
  • Portal Hypertension
  • Hepatitis C
  • Fatigue
  • Hepatic Cirrhosis
  • Liver Disorder
  • Nasopharyngitis
  • Activities Of Daily Living Impaired
  • Renal Disorder
Drugs used concurrently:
  • Seroquel
  • Seroquel
  • Lasix
  • Zoloft
  • Seroquel
The patient was hospitalized. Although Methadone Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Serotonin Syndrome, Tremor, Anxiety, Musculoskeletal Stiffness, Condition Aggravated, Insomnia, Muscular Weakness, Hyperhidrosis, Fatigue

An adverse event was reported by a health professional on Jan 30, 2012 by a male taking Methadone Hcl (dosage: NA) . Location: UNITED STATES , 45 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methadone side effects: serotonin syndrome, tremor, anxiety, musculoskeletal stiffness, condition aggravated, insomnia, muscular weakness, hyperhidrosis, fatigue. Additional medications/treatments:
Associated medications used:
  • Desipramine Hydrochloride (10 Mg;hs;po)
Anaemia, Dyspnoea Exertional, Fatigue

This Fatigue problem was reported by a physician from UNITED STATES. A 29-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Aug 01, 2010 a consumer started treatment with Methadone Hcl (dosage: NA). The following drugs/medications were being taken at the same time:
  • Carisoprodol
  • Ativan
  • Opana
  • Exjade (10000 Mg, Qd, Oral)
When commencing Methadone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Anaemia
  • Dyspnoea Exertional
  • Fatigue
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Serotonin Syndrome, Hyperreflexia, Tremor, Fatigue, Insomnia, Musculoskeletal Stiffness, Anxiety, Intentional Overdose

This is a Methadone Hcl side effect report of a 45-year-old patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Methadone Hcl (dosage: Dose: More Than Twice The Prescribed Dose.) starting NS. Concurrently used drugs:
  • Desipramine Hydrochloride
Soon after that, the consumer experienced the following of symptoms:
  • Serotonin Syndrome
  • Hyperreflexia
  • Tremor
  • Fatigue
  • Insomnia
  • Musculoskeletal Stiffness
  • Anxiety
  • Intentional Overdose
This opens a possibility that Methadone Hcl could cause Fatigue and that some patients may be more susceptible.
Hypertension, Insomnia, Microalbuminuria, Fatigue, Vertigo, Ear Pain, Sleep Disorder

This Fatigue side effect was reported by a consumer or non-health professional from UNITED STATES on Mar 11, 2011. A female patient from UNITED STATES , 43 years of age, weighting 175.0 lb, was treated with Methadone Hcl. Directly after treatment started, patient experienced the unwanted or unexpected Methadone side effects: hypertension, insomnia, microalbuminuria, fatigue, vertigo, ear pain, sleep disorder. Methadone Hcl dosage: NA.
Associated medications used:
  • Seroquel Xr
  • Insulin
  • Xanax
  • Seroquel Xr
These side effects may potentially be related to Methadone Hcl.
Weight Increased, Prostatic Specific Antigen Increased, Fatigue, Hypersomnia

This Fatigue side effect was reported by a consumer or non-health professional from UNITED STATES. A patient (weight:NA) experienced the following symptoms/conditions: pain,prostate cancer,blood cholesterol. The patient was prescribed Methadone Hcl (dosage: NA), which was started on Jan 01, 2009. Concurrently used drugs:
  • Lupron
  • Simvastatin
  • Zytiga (Strength: 250 Mg)
  • Promethegan
  • Famotidine
  • Xgeva
When starting to take Methadone Hcl the consumer reported the following symptoms:
  • Weight Increased
  • Prostatic Specific Antigen Increased
  • Fatigue
  • Hypersomnia
These side effects may potentially be related to Methadone Hcl.
Oedema Peripheral, Blister, Fatigue, Erythema, Mental Impairment, Dyspnoea, Malaise, Burning Sensation, Feeling Abnormal

This Fatigue Methadone side effect was reported by a consumer or non-health professional from UNITED STATES on Jul 21, 2011. A Female , weighting 185.0 lb, was diagnosed with and was treated with Methadone. The patient presented the following health conditions:
  • Oedema Peripheral
  • Blister
  • Fatigue
  • Erythema
  • Mental Impairment
  • Dyspnoea
  • Malaise
  • Burning Sensation
  • Feeling Abnormal
. Methadone dosage: 20 Mg, As Needed. Additional drugs used at the same time:
  • Lyrica (50 Mg, 3x/day)
  • Lisinopril (Unk)
  • Lyrica (75 Mg, 3x/day)
Neck Injury, Stress, Fatigue, Pain, Joint Injury, Back Injury, Tremor, Malaise, Insomnia

This is a Methadone Hcl side effect report of a 46-year-old patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: pain, who was treated with Methadone Hcl (dosage:10 Mg, Oral, start time: NS), combined with:
  • Savella (Oral)
  • Metoprolol Succinate
  • Lyrica (300 Mg (100 Mg, 3 In 1 D), Oral)
  • Motrin
, and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Neck Injury
  • Stress
  • Fatigue
  • Pain
  • Joint Injury
  • Back Injury
  • Tremor
  • Malaise
  • Insomnia
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methadone Hcl treatment in patients suffering from pain, resulting in Fatigue.
Haematocrit Decreased, Fatigue

A female patient (weight: NA) from UNITED STATES with the following symptoms: arthralgia started Methadone Hcl treatment (dosage: Unk) on NS. Soon after starting Methadone Hcl treatment, the consumer experienced several side effects, including:
  • Haematocrit Decreased
  • Fatigue
. Concurrently used drugs:
  • Percocet (Unk)
  • Soliris (Unk)
This finding indicates that some patients can be more vulnerable to developing Methadone Hcl side effects, such as Fatigue.
Abnormal Dreams, Dizziness, Fatigue, Nightmare, Overdose, Pruritus, Sleep Disorder

A patient from was prescribed and started Methadone Hcl on Aug 03, 2010. After Methadone was administered, patient encountered several Methadone side effects: abnormal dreams, dizziness, fatigue, nightmare, overdose, pruritus, sleep disorder Additional patient health information: male , 20 years of age, weighting 165.3 lb, The consumer reported the following symptoms: . Methadone Hcl dosage: NA. Concurrently used drugs:
  • Chantix (0.5 Mg)
  • Chantix (1 Mg)
  • Nicotine
  • Caffeine
  • Coffee
  • Seroquel
Abnormal Dreams, Dizziness, Fatigue, Nightmare, Overdose, Pruritus, Sleep Disorder

This report suggests a potential Methadone Hcl Fatigue side effect(s) that can have serious consequences. A 20-year-old patient from (weight:NA) was diagnosed with the following health condition(s): NA and used Methadone Hcl (dosage: NA) starting Jan 01, 2008. Soon after starting Methadone Hcl the patient began experiencing various side effects, including:
  • Abnormal Dreams
  • Dizziness
  • Fatigue
  • Nightmare
  • Overdose
  • Pruritus
  • Sleep Disorder
Drugs used concurrently:
  • Chantix (0.5 Mg)
  • Chantix (1 Mg)
  • Nicotine
  • Caffeine
  • Coffee
  • Seroquel
Although Methadone Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Abnormal Dreams, Dizziness, Fatigue, Nightmare, Overdose, Pruritus, Sleep Disorder

An adverse event was reported by a consumer or non-health professional on Jul 16, 2010 by a male taking Methadone Hcl (dosage: NA) . Location: , 20 years of age, weighting 165.3 lb, patient began experiencing various side effects, including: Patient felt the following Methadone side effects: abnormal dreams, dizziness, fatigue, nightmare, overdose, pruritus, sleep disorder. Additional medications/treatments:
Multiple prescriptions taken:
  • Chantix (0.5 Mg)
  • Chantix (1 Mg)
  • Nicotine
  • Caffeine
  • Coffee
  • Seroquel
Blood Alkaline Phosphatase Increased, Blood Pressure Increased, Decreased Appetite, Dysgeusia, Fatigue, Insomnia, Nausea, Neutrophil Count Increased, Psychotic Disorder

This Fatigue problem was reported by a physician from . A female patient (weight: NA) was diagnosed with the following medical condition(s): pain.On Jan 01, 2003 a consumer started treatment with Methadone Hcl (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Methadone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Blood Alkaline Phosphatase Increased
  • Blood Pressure Increased
  • Decreased Appetite
  • Dysgeusia
  • Fatigue
  • Insomnia
  • Nausea
  • Neutrophil Count Increased
  • Psychotic Disorder
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Confusional State, Depressed Level Of Consciousness, Dizziness, Dyspnoea, Fatigue, Gait Disturbance, Hypoventilation, Overdose, Somnolence

This is a Methadone Hcl side effect report of a 61-year-old patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Methadone Hcl (dosage: 10 Forget Po) starting Oct 10, 2007. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Confusional State
  • Depressed Level Of Consciousness
  • Dizziness
  • Dyspnoea
  • Fatigue
  • Gait Disturbance
  • Hypoventilation
  • Overdose
  • Somnolence
This opens a possibility that Methadone Hcl could cause Fatigue and that some patients may be more susceptible.
Fatigue, Middle Insomnia, Snoring, Therapeutic Agent Toxicity

This Fatigue side effect was reported by a consumer or non-health professional from UNITED STATES on Jun 29, 2009. A patient from UNITED STATES , 48 years of age, weighting 275.0 lb, was diagnosed with and was treated with Methadone Hcl. Patient felt the following Methadone side effects: fatigue, middle insomnia, snoring, therapeutic agent toxicity. Methadone Hcl dosage: NA. These side effects may potentially be related to Methadone Hcl.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methadone Fatigue Causes and Reviews


Everyone feels tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your Fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to Fatigue. These include

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme Fatigue is chronic Fatigue syndrome (CFS). This Fatigue is not the kind of tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging


Methadone Fatigue Reviews

Tue, 09 Feb 2010

good afternoon doc,my name dimasautisme,i comefrom indonesia ?
im Methadoners with 120 mg,im drink ARV to?please private my status?
i just want quesstion i want to detox,where i must go to hospital doc?
please help me :-D :)

Mon, 27 Dec 2010

I have been on Methadone for two years. Went fro
70 mgs a day to 20. I do for pain and I have been prescribed klonipin also recently for severe panic attacks and I read online that it's a deadly combo. I take my Methadone at 9 am. And have panic attacks around 10 pm every night before I sleep . Is this enough time apart to take them? Thank you

Thu, 31 Mar 2011
ive been takeing 90mls of Methadone for approxamitley 2 years on and off but properly this time for a total off 7 months i get servere sweating from taking my Methadone and feel very hot like im burning up and dripping with sweat why is this happening and what can i do and also im a type 2 diabetic and my Methadone is makeing my sugars drop really low what could be causing this and what can be done please help! thankyou katie .
Sat, 20 Aug 2011
Methodone Side Effects, I have had many trips to Emergency Unit at my Town, having tight painful heart problems. But when they do the Tests for Heart attacks, I jave always been told I have no problem my heart is fine. I have had ECG Tests, all fine. The only thing I can put it to ie: 250 milligrams of Methodone Tablet for Chronic Pain at the highest point was 50 x 5mg Tablest per day. I have had my leg amputated which I had the medication for. Can you confirm what I should be asking my GP, and what literature orResearch papers I can refer to. Thank you Geoff perry
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Intentional Overdose (27)
Constipation (27)
Feeling Abnormal (26)
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