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Methadone Respiratory Depression Side Effects

Methadone Respiratory Depression Side Effect Reports


The following Methadone Respiratory Depression side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Respiratory Depression, can occur, and what you can do about them.

A side effect could appear soon after you start Methadone or it might take time to develop.



Bradycardia, Miosis, Somnolence, Respiratory Depression

This Respiratory Depression side effect was reported by a pharmacist from US. A 62-year-old patient (weight:NA) experienced the following symptoms/conditions: pain. The patient was prescribed Methadone (dosage: NA), which was started on Nov 18, 2013. Concurrently used drugs:
  • Oxycodone
When starting to take Methadone the consumer reported the following symptoms:
  • Bradycardia
  • Miosis
  • Somnolence
  • Respiratory Depression
The patient was hospitalized. These side effects may potentially be related to Methadone.
Toxicity To Various Agents, Respiratory Depression, Cellulitis, Acidosis, Constipation

This Respiratory Depression Methadone side effect was reported by a health professional from COUNTRY NOT SPECIFIED on Aug 28, 2013. A male , 48 years of age, was diagnosed with and was treated with Methadone. The patient presented the following health conditions:
  • Toxicity To Various Agents
  • Respiratory Depression
  • Cellulitis
  • Acidosis
  • Constipation
. Methadone dosage: NA. Additional drugs used at the same time: NA.
Accidental Poisoning, Bronchopneumonia, Respiratory Depression, Cardiopulmonary Failure

This is a Methadone Oral Unflavored side effect report of a 39-year-old patient (weight:NA) from BE, suffering from the following symptoms/conditions: NA, who was treated with Methadone Oral Unflavored (dosage:Unk, start time: NS), combined with: NA., and developed a serious reaction and a Respiratory Depression side effect. The patient presented with:
  • Accidental Poisoning
  • Bronchopneumonia
  • Respiratory Depression
  • Cardiopulmonary Failure
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methadone Oral Unflavored treatment in patients suffering from NA, resulting in Respiratory Depression.

Sedation, Respiratory Depression, Hypotension, Hypoxia

A 63-year-old patient (weight: NA) from US with the following symptoms: non-small cell lung cancer started Methadone treatment (dosage: NA) on Jan 15, 2012. Soon after starting Methadone treatment, the consumer experienced several side effects, including:
  • Sedation
  • Respiratory Depression
  • Hypotension
  • Hypoxia
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Methadone side effects, such as Respiratory Depression.
Respiratory Depression, Arrhythmia, Toxicity To Various Agents, Accidental Overdose

A patient from UNITED KINGDOM was prescribed and started Methadone Hcl on Apr 10, 2012. Patient felt the following Methadone side effects: respiratory depression, arrhythmia, toxicity to various agents, accidental overdose Additional patient health information: Patient , 54 years of age, The consumer reported the following symptoms: . Methadone Hcl dosage: NA. Concurrently used drugs:
  • Metoclopramide
  • Acetaminophen
  • Citalopram Hydrobromide (Unk)
Respiratory Depression

This report suggests a potential Methadone Hcl Respiratory Depression side effect(s) that can have serious consequences. A 28-year-old patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): pain and used Methadone Hcl (dosage: 2tabs) starting Aug 25, 2009. Soon after starting Methadone Hcl the patient began experiencing various side effects, including:
  • Respiratory Depression
Drugs used concurrently:NA. Although Methadone Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Respiratory Depression, may still occur.
Dysarthria, Toxicologic Test Abnormal, Lethargy, Respiratory Depression, Electrocardiogram Qt Prolonged, Mental Status Changes

An adverse event was reported by a pharmacist on Mar 13, 2012 by a male taking Methadone Hcl (dosage: NA) . Location: UNITED STATES , 56 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methadone side effects: dysarthria, toxicologic test abnormal, lethargy, respiratory depression, electrocardiogram qt prolonged, mental status changes. Additional medications/treatments:
Associated medications used:
  • Alprazolam
Respiratory Depression

This Respiratory Depression problem was reported by a pharmacist from UNITED STATES. A 65-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Dec 20, 2011 a consumer started treatment with Methadone Hcl (dosage: 90 Mg Am Po). The following drugs/medications were being taken at the same time: NA. When commencing Methadone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Respiratory Depression
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Respiratory Depression, may become evident only after a product is in use by the general population.
Respiratory Depression, Headache, Somnolence, Nausea, Hypotension, Oxygen Saturation Decreased

This is a Methadone Hcl side effect report of a 59-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Methadone Hcl (dosage: 6 Mg, Intravenous Days 1 And 15) starting NS. Concurrently used drugs:
  • Letrozole (2.5 Mg, 1 In 1 D, Oral Days 8-14)
Soon after that, the consumer experienced the following of symptoms:
  • Respiratory Depression
  • Headache
  • Somnolence
  • Nausea
  • Hypotension
  • Oxygen Saturation Decreased
This opens a possibility that Methadone Hcl could cause Respiratory Depression and that some female patients may be more susceptible.
Respiratory Depression, Toxicity To Various Agents

This Respiratory Depression side effect was reported by a consumer or non-health professional from UNITED STATES on Jan 03, 2012. A patient from UNITED STATES , 62 years of age, was treated with Methadone Hcl. Directly after treatment started, patient experienced the unwanted or unexpected Methadone side effects: respiratory depression, toxicity to various agents. Methadone Hcl dosage: NA. These side effects may potentially be related to Methadone Hcl.
Respiratory Depression, Toxicity To Various Agents

This Respiratory Depression side effect was reported by a consumer or non-health professional from UNITED STATES. A 34-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methadone Hcl (dosage: NA), which was started on NS. Concurrently used drugs: NA. When starting to take Methadone Hcl the consumer reported the following symptoms:
  • Respiratory Depression
  • Toxicity To Various Agents
These side effects may potentially be related to Methadone Hcl.
Somnolence, Hypotension, Headache, Nausea, Respiratory Depression

This Respiratory Depression Methadone Hcl side effect was reported by a health professional from UNITED STATES on Dec 21, 2011. A Female , 59 years of age, weighting 191.8 lb, was treated with Methadone Hcl. The patient presented the following health conditions:
  • Somnolence
  • Hypotension
  • Headache
  • Nausea
  • Respiratory Depression
. Methadone Hcl dosage: 6mg Dose Given On Days 1 And 15. Additional drugs used at the same time:
  • Letrozole
Toxicity To Various Agents, Overdose, Respiratory Depression

This is a Methadone Hcl side effect report of a 24-year-old patient (weight:NA) from AUSTRALIA, suffering from the following symptoms/conditions: NA, who was treated with Methadone Hcl (dosage:NA, start time: NS), combined with:
  • Diazepam
  • Amitriptyline Hcl
  • Oxazepam
, and developed a serious reaction and a Respiratory Depression side effect. The patient presented with:
  • Toxicity To Various Agents
  • Overdose
  • Respiratory Depression
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methadone Hcl treatment in patients suffering from NA, resulting in Respiratory Depression.
Respiratory Depression, Hypoglycaemia, Accidental Overdose, Electrocardiogram Qt Prolonged, Hypotension, Depressed Level Of Consciousness, Sinus Tachycardia, Pneumonia, Ventricular Extrasystoles

A 21-year-old female patient (weight: NA) from HONG KONG with the following symptoms: NA started Methadone Hcl treatment (dosage: 800 Mg, Unk) on NS. Soon after starting Methadone Hcl treatment, the consumer experienced several side effects, including:
  • Respiratory Depression
  • Hypoglycaemia
  • Accidental Overdose
  • Electrocardiogram Qt Prolonged
  • Hypotension
  • Depressed Level Of Consciousness
  • Sinus Tachycardia
  • Pneumonia
  • Ventricular Extrasystoles
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methadone Hcl side effects, such as Respiratory Depression.
Respiratory Depression, Electrocardiogram Qt Prolonged, Hypoglycaemia, Accidental Overdose, Coma, Hypotension

A female patient from HONG KONG was prescribed and started Methadone Hcl on Sep 03, 2011. After Methadone was administered, patient encountered several Methadone side effects: respiratory depression, electrocardiogram qt prolonged, hypoglycaemia, accidental overdose, coma, hypotension Additional patient health information: Female , 21 years of age, The consumer reported the following symptoms: was diagnosed with and. Methadone Hcl dosage: NA. Concurrently used drugs: NA. The patient was hospitalized.
Accidental Overdose, Blood Cortisol Increased, Respiratory Depression, Electrocardiogram Qt Prolonged, Platelet Count Increased, Blood Creatinine Increased, Alanine Aminotransferase Increased, Troponin I Increased, Pneumonia

This report suggests a potential Methadone Hcl Respiratory Depression side effect(s) that can have serious consequences. A 21-year-old female patient from HONG KONG (weight:NA) was diagnosed with the following health condition(s): accidental overdose and used Methadone Hcl (dosage: NA) starting NS. Soon after starting Methadone Hcl the patient began experiencing various side effects, including:
  • Accidental Overdose
  • Blood Cortisol Increased
  • Respiratory Depression
  • Electrocardiogram Qt Prolonged
  • Platelet Count Increased
  • Blood Creatinine Increased
  • Alanine Aminotransferase Increased
  • Troponin I Increased
  • Pneumonia
Drugs used concurrently:NA. The patient was hospitalized. Although Methadone Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Respiratory Depression, may still occur.
Snoring, Pulmonary Oedema, Overdose, Needle Track Marks, Toxicity To Various Agents, Pneumonia, Respiratory Depression, Aspiration, Pulmonary Congestion

An adverse event was reported by a health professional on Aug 04, 2011 by a Patient taking Methadone Hcl (dosage: 0.2 Mg/l; ;) . Location: AUSTRALIA , 46 years of age, patient began experiencing various side effects, including: Patient felt the following Methadone side effects: snoring, pulmonary oedema, overdose, needle track marks, toxicity to various agents, pneumonia, respiratory depression, aspiration, pulmonary congestion. Additional medications/treatments:
Multiple prescriptions taken:
  • Venlafaxine Hydrochloride
Pulmonary Oedema, Overdose, Aspiration, Pulmonary Congestion, Toxicity To Various Agents, Respiratory Depression, Needle Track Marks

This Respiratory Depression problem was reported by a health professional from AUSTRALIA. A 34-year-old patient (weight: NA) was diagnosed with the following medical condition(s): overdose.On NS a consumer started treatment with Methadone Hcl (dosage: 1.9 Mg/l). The following drugs/medications were being taken at the same time:
  • Nordiazepam (no Pref. Name)
  • Methamphetamine Hydrochloride
  • Alprazolam
When commencing Methadone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Pulmonary Oedema
  • Overdose
  • Aspiration
  • Pulmonary Congestion
  • Toxicity To Various Agents
  • Respiratory Depression
  • Needle Track Marks
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Respiratory Depression, may become evident only after a product is in use by the general population.
Respiratory Depression, Somnolence, Pleural Disorder, Aspiration, Pulmonary Oedema, Incorrect Dose Administered, Toxicity To Various Agents, Overdose

This is a Methadone Hcl side effect report of a 22-year-old patient (weight: NA) from AUSTRALIA. The patient developed the following symptoms/conditions: overdose and was treated with Methadone Hcl (dosage: 1.2 Mg/l;x1) starting NS. Concurrently used drugs:
  • Alprazolam (37 Tablets;x1)
  • Quetiapine Fumarate
Soon after that, the consumer experienced the following of symptoms:
  • Respiratory Depression
  • Somnolence
  • Pleural Disorder
  • Aspiration
  • Pulmonary Oedema
  • Incorrect Dose Administered
  • Toxicity To Various Agents
  • Overdose
This opens a possibility that Methadone Hcl could cause Respiratory Depression and that some patients may be more susceptible.
Pulmonary Oedema, Overdose, Pulmonary Congestion, Respiratory Depression, Stupor, Foaming At Mouth, Snoring, Toxicity To Various Agents, Pneumonia Aspiration

This Respiratory Depression side effect was reported by a health professional from AUSTRALIA on Aug 04, 2011. A patient from AUSTRALIA , 35 years of age, was treated with Methadone Hcl. Patient felt the following Methadone side effects: pulmonary oedema, overdose, pulmonary congestion, respiratory depression, stupor, foaming at mouth, snoring, toxicity to various agents, pneumonia aspiration. Methadone Hcl dosage: 0.2mg/l.
Multiple prescriptions taken:
  • Nordiazepam (no Pref. Name)
  • Diazepam
  • D-9-thc (no Pref. Name)
  • Benztropine Mesylate
  • Quetiapine Fumarate
  • Codeine Sulfate
  • Fluoxetine Hydrochloride
These side effects may potentially be related to Methadone Hcl.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methadone Respiratory Depression Causes and Reviews


What is respiratory failure?

Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.

When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.

Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.

What causes respiratory failure?

Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include

  • Lung diseases such as COPD (chronic obstructive pulmonary disease), cystic fibrosis, pneumonia, and pulmonary embolism
  • Conditions that affect the nerves and muscles that control breathing, such as amyotrophic lateral sclerosis (ALS), muscular dystrophy, spinal cord injuries, and stroke
  • Problems with the spine, such as scoliosis (a curve in the spine). They can affect the bones and muscles used for breathing.
  • Damage to the tissues and ribs around the lungs. An injury to the chest can cause this damage.
  • Drug or alcohol overdose
  • Inhalation injuries, such as from inhaling smoke (from fires) or harmful fumes
What are the symptoms of respiratory failure?

The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.

A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.

Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.

How is respiratory failure diagnosed?

Your health care provider will diagnose respiratory failure based on

  • Your medical history
  • A physical exam, which often includes
    • Listening to your lungs to check for abnormal sounds
    • Listening to your heart to check for arrhythmia
    • Looking for a bluish color on your skin, lips, and fingernails
  • Diagnostic tests, such as
    • Pulse oximetry, a small sensor that uses a light to measure how much oxygen is in your blood. The sensor goes on the end of your finger or on your ear.
    • Arterial blood gas test, a test that measures the oxygen and carbon dioxide levels in your blood. The blood sample is taken from an artery, usually in your wrist.

Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.

What are the treatments for respiratory failure?

Treatment for respiratory failure depends on

  • Whether it is acute (short-term) or chronic (ongoing)
  • How severe it is
  • What is causing it

Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.

One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include

  • Oxygen therapy, through a nasal cannula (two small plastic tubes that go in your nostrils) or through a mask that fits over your nose and mouth
  • Tracheostomy, a surgically-made hole that goes through the front of your neck and into your windpipe. A breathing tube, also called a tracheostomy, or trach tube, is placed in the hole to help you breathe.
  • Ventilator, a breathing machine that blows air into your lungs. It also carries carbon dioxide out of your lungs.
  • Other breathing treatments, such as noninvasive positive pressure ventilation (NPPV), which uses mild air pressure to keep your airways open while you sleep. Another treatment is a special bed that rocks back and forth, to help you breathe in and out.
  • Fluids, often through an intravenous (IV), to improve blood flow throughout your body. They also provide nutrition.
  • Medicines for discomfort
  • Treatments for the cause of the respiratory failure. These treatments may include medicines and procedures.

If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.

If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.

Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.

NIH: National Heart, Lung, and Blood Institute


Methadone Respiratory Depression Reviews

Tue, 09 Feb 2010

good afternoon doc,my name dimasautisme,i comefrom indonesia ?
im Methadoners with 120 mg,im drink ARV to?please private my status?
i just want quesstion i want to detox,where i must go to hospital doc?
please help me :-D :)

Mon, 27 Dec 2010

I have been on Methadone for two years. Went fro
70 mgs a day to 20. I do for pain and I have been prescribed klonipin also recently for severe panic attacks and I read online that it's a deadly combo. I take my Methadone at 9 am. And have panic attacks around 10 pm every night before I sleep . Is this enough time apart to take them? Thank you

Thu, 31 Mar 2011
ive been takeing 90mls of Methadone for approxamitley 2 years on and off but properly this time for a total off 7 months i get servere sweating from taking my Methadone and feel very hot like im burning up and dripping with sweat why is this happening and what can i do and also im a type 2 diabetic and my Methadone is makeing my sugars drop really low what could be causing this and what can be done please help! thankyou katie .
Sat, 20 Aug 2011
Methodone Side Effects, I have had many trips to Emergency Unit at my Town, having tight painful heart problems. But when they do the Tests for Heart attacks, I jave always been told I have no problem my heart is fine. I have had ECG Tests, all fine. The only thing I can put it to ie: 250 milligrams of Methodone Tablet for Chronic Pain at the highest point was 50 x 5mg Tablest per day. I have had my leg amputated which I had the medication for. Can you confirm what I should be asking my GP, and what literature orResearch papers I can refer to. Thank you Geoff perry
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Methadone Side Effects

Toxicity To Various Agents (601)
Cardiac Arrest (334)
Respiratory Arrest (316)
Completed Suicide (256)
Overdose (197)
Death (147)
Electrocardiogram Qt Prolonged (142)
Torsade De Pointes (97)
Respiratory Depression (82)
Cardio-respiratory Arrest (73)
Somnolence (65)
Accidental Overdose (59)
Nausea (57)
Pulmonary Oedema (57)
Loss Of Consciousness (54)
Vomiting (51)
Confusional State (47)
Pneumonia (40)
Dyspnoea (39)
Syncope (39)
Mental Status Changes (38)
Pain (37)
Fall (37)
Sedation (36)
Bronchopneumonia (36)
Dizziness (35)
Hypotension (31)
Convulsion (31)
Hyperhidrosis (31)
Malaise (30)
Depressed Level Of Consciousness (30)
Coma (29)
Unresponsive To Stimuli (27)
Intentional Overdose (27)
Constipation (27)
Feeling Abnormal (26)
Hypokalaemia (26)
Pulmonary Congestion (26)
Renal Failure Acute (26)
Ventricular Tachycardia (25)
Headache (25)
Fatigue (25)
Brain Oedema (25)
Lethargy (24)
Rhabdomyolysis (24)
Respiratory Failure (24)
Incorrect Dose Administered (23)
Bradycardia (23)
Accidental Poisoning (23)
Miosis (22)

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