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Methadone Rhabdomyolysis Side Effects

Methadone Rhabdomyolysis Side Effect Reports


The following Methadone Rhabdomyolysis side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Rhabdomyolysis, can occur, and what you can do about them.

A side effect could appear soon after you start Methadone or it might take time to develop.



Toxicity To Various Agents, Brain Injury, Unresponsive To Stimuli, Multi-organ Failure, Rhabdomyolysis, Renal Failure Acute, Central Nervous System Necrosis, Pulmonary Oedema, Dyspnoea

This Rhabdomyolysis side effect was reported by a health professional from US. A 23-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methadone (dosage: 40 Mg, Unk), which was started on NS. Concurrently used drugs:
  • Alprazolam (3 Mg, Unk)
  • Heroin
  • Cannabinoids
When starting to take Methadone the consumer reported the following symptoms:
  • Toxicity To Various Agents
  • Brain Injury
  • Unresponsive To Stimuli
  • Multi-organ Failure
  • Rhabdomyolysis
  • Renal Failure Acute
  • Central Nervous System Necrosis
  • Pulmonary Oedema
  • Dyspnoea
The patient was hospitalized. These side effects may potentially be related to Methadone.
Brain Injury, Rhabdomyolysis, Multi-organ Failure, Cardio-respiratory Arrest, Coma

This Rhabdomyolysis Methadone side effect was reported by a physician from US on Sep 23, 2013. A male , 23 years of age, was treated with Methadone. The patient presented the following health conditions:
  • Brain Injury
  • Rhabdomyolysis
  • Multi-organ Failure
  • Cardio-respiratory Arrest
  • Coma
. Methadone dosage: 40 Mg, Single. Additional drugs used at the same time:
  • Alprazolam (3 Mg, Single)
  • Cannabis (Unk)
Toxicity To Various Agents, Brain Injury, Unresponsive To Stimuli, Rhabdomyolysis, Multi-organ Failure, Renal Failure Acute, Pulmonary Oedema

This is a Methadone side effect report of a 23-year-old patient (weight:NA) from COUNTRY NOT SPECIFIED, suffering from the following symptoms/conditions: NA, who was treated with Methadone (dosage:NA, start time: NS), combined with:
  • Alprazolam
  • Cannabinoids
, and developed a serious reaction and a Rhabdomyolysis side effect. The patient presented with:
  • Toxicity To Various Agents
  • Brain Injury
  • Unresponsive To Stimuli
  • Rhabdomyolysis
  • Multi-organ Failure
  • Renal Failure Acute
  • Pulmonary Oedema
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methadone treatment in patients suffering from NA, resulting in Rhabdomyolysis.

Rhabdomyolysis, Renal Failure Acute, Fall, Dehydration

A 41-year-old patient (weight: NA) from COUNTRY NOT SPECIFIED with the following symptoms: NA started Methadone treatment (dosage: NA) on NS. Soon after starting Methadone treatment, the consumer experienced several side effects, including:
  • Rhabdomyolysis
  • Renal Failure Acute
  • Fall
  • Dehydration
. Concurrently used drugs:
  • Heroin
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methadone side effects, such as Rhabdomyolysis.
Arrhythmia, Coma, Rhabdomyolysis

A female patient from US was prescribed and started Methadone on Apr 09, 2013. Patient felt the following Methadone side effects: arrhythmia, coma, rhabdomyolysis Additional patient health information: Female , 71 years of age, weighting 154.0 lb, The consumer reported the following symptoms: was diagnosed with and. Methadone dosage: NA. Concurrently used drugs: NA. The patient was hospitalized.
Rhabdomyolysis, Renal Failure Acute, Hypotension, Vomiting, Fall, Headache, Pyrexia, Somnolence, Altered State Of Consciousness

This report suggests a potential Methadone Rhabdomyolysis side effect(s) that can have serious consequences. A 41-year-old patient from ES (weight:NA) was diagnosed with the following health condition(s): NA and used Methadone (dosage: NA) starting NS. Soon after starting Methadone the patient began experiencing various side effects, including:
  • Rhabdomyolysis
  • Renal Failure Acute
  • Hypotension
  • Vomiting
  • Fall
  • Headache
  • Pyrexia
  • Somnolence
  • Altered State Of Consciousness
Drugs used concurrently:NA. The patient was hospitalized. Although Methadone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rhabdomyolysis, may still occur.
Rhabdomyolysis, Altered State Of Consciousness, Headache, Nausea, Vomiting, Pyrexia, Somnolence, Feeling Abnormal, Hypotension

An adverse event was reported by a health professional on Oct 08, 2012 by a male taking Methadone (dosage: NA) . Location: ES , 41 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methadone side effects: rhabdomyolysis, altered state of consciousness, headache, nausea, vomiting, pyrexia, somnolence, feeling abnormal, hypotension. Additional medications/treatments: The patient was hospitalized.
Convulsion, Toxicity To Various Agents, Rhabdomyolysis, Grand Mal Convulsion, Treatment Noncompliance, Postictal State

This Rhabdomyolysis problem was reported by a health professional from UNITED STATES. A 56-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Methadone Hcl (dosage: NA). The following drugs/medications were being taken at the same time:
  • Lamotrgine
  • Clonazepam
When commencing Methadone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Convulsion
  • Toxicity To Various Agents
  • Rhabdomyolysis
  • Grand Mal Convulsion
  • Treatment Noncompliance
  • Postictal State
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Rhabdomyolysis, may become evident only after a product is in use by the general population.
Rhabdomyolysis, Hypoxic-ischaemic Encephalopathy, Renal Failure Acute

This is a Methadone Hcl side effect report of a 56-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: intentional overdose and was treated with Methadone Hcl (dosage: Unk) starting NS. Concurrently used drugs:
  • Fentanyl Citrate (Unk)
Soon after that, the consumer experienced the following of symptoms:
  • Rhabdomyolysis
  • Hypoxic-ischaemic Encephalopathy
  • Renal Failure Acute
The patient was hospitalized and became disabled. This opens a possibility that Methadone Hcl could cause Rhabdomyolysis and that some female patients may be more susceptible.
Rhabdomyolysis, Brain Oedema, Multi-organ Failure, Toxicity To Various Agents, Disseminated Intravascular Coagulation, Cardiac Arrest

This Rhabdomyolysis side effect was reported by a physician from UNITED STATES on Mar 13, 2012. A patient from UNITED STATES , 40 years of age, was treated with Methadone Hcl. Directly after treatment started, patient experienced the unwanted or unexpected Methadone side effects: rhabdomyolysis, brain oedema, multi-organ failure, toxicity to various agents, disseminated intravascular coagulation, cardiac arrest. Methadone Hcl dosage: NA.
Associated medications used:
  • Alcohol
  • Cannabis
These side effects may potentially be related to Methadone Hcl.
Rhabdomyolysis, Vasospasm, Blood Creatine Phosphokinase Increased

This Rhabdomyolysis side effect was reported by a physician from GERMANY. A patient (weight:NA) experienced the following symptoms/conditions: dependence. The patient was prescribed Methadone Hcl (dosage: Unk Mg, Unk), which was started on Jun 25, 2011. Concurrently used drugs: NA. When starting to take Methadone Hcl the consumer reported the following symptoms:
  • Rhabdomyolysis
  • Vasospasm
  • Blood Creatine Phosphokinase Increased
The patient was hospitalized. These side effects may potentially be related to Methadone Hcl.
Peripheral Ischaemia, Rhabdomyolysis

This Rhabdomyolysis Methadone Hydrochloride side effect was reported by a physician from UNITED STATES on Oct 13, 2010. A male , 34 years of age, was treated with Methadone Hydrochloride. The patient presented the following health conditions:
  • Peripheral Ischaemia
  • Rhabdomyolysis
. Methadone Hydrochloride dosage: 10 10 Mg Tablets. Additional drugs used at the same time: NA. The patient was hospitalized.
Delirium, Duodenal Ulcer, Hypersomnia, Hypotension, Overdose, Renal Failure Acute, Rhabdomyolysis

This is a Methadone side effect report of a 43-year-old patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: procedural pain, who was treated with Methadone (dosage:40mg Tid Po, Recent, start time: NS), combined with:
  • Norvasc
  • Clonazepam
  • Ferrous Sulfate Tab
  • Gabapentin
  • Vactobacillus
  • Lamotrigine
  • Lisinopril
  • Keppra
, and developed a serious reaction and a Rhabdomyolysis side effect. The patient presented with:
  • Delirium
  • Duodenal Ulcer
  • Hypersomnia
  • Hypotension
  • Overdose
  • Renal Failure Acute
  • Rhabdomyolysis
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methadone treatment in patients suffering from procedural pain, resulting in Rhabdomyolysis.
Fall, Rhabdomyolysis, Sedation

A 62-year-old patient (weight: NA) from UNITED STATES with the following symptoms: pain started Methadone Hydrochloride treatment (dosage: 10 Mg Tid Po) on Jan 06, 2009. Soon after starting Methadone Hydrochloride treatment, the consumer experienced several side effects, including:
  • Fall
  • Rhabdomyolysis
  • Sedation
. Concurrently used drugs:
  • Gabapentin (1200 Mg Tid Po)
  • Amitriptyline Hcl
  • Tizanidine Hcl
The patient was hospitalized and became disabled. This finding indicates that some patients can be more vulnerable to developing Methadone Hydrochloride side effects, such as Rhabdomyolysis.
Fall, Rhabdomyolysis, Sedation

A patient from UNITED STATES was prescribed and started Methadone Hcl on Feb 12, 2010. After Methadone was administered, patient encountered several Methadone side effects: fall, rhabdomyolysis, sedation Additional patient health information: male , 62 years of age, The consumer reported the following symptoms: was diagnosed with and. Methadone Hcl dosage: 10 Mg Tid Po. Concurrently used drugs:
  • Gabapentin (1200 Mg Tid Po)
The patient was hospitalized and became disabled.
Cyanosis, Emotional Distress, Hypoaesthesia, Pain In Extremity, Peripheral Ischaemia, Pigmentation Disorder, Rhabdomyolysis

This report suggests a potential Methadone (ngx) (methadone) Tablet Rhabdomyolysis side effect(s) that can have serious consequences. A 34-year-old patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Methadone (ngx) (methadone) Tablet (dosage: 100 Mg, (crushed Tablet In Water), Intra-arterial) starting NS. Soon after starting Methadone (ngx) (methadone) Tablet the patient began experiencing various side effects, including:
  • Cyanosis
  • Emotional Distress
  • Hypoaesthesia
  • Pain In Extremity
  • Peripheral Ischaemia
  • Pigmentation Disorder
  • Rhabdomyolysis
Drugs used concurrently:NA. The patient was hospitalized. Although Methadone (ngx) (methadone) Tablet demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rhabdomyolysis, may still occur.
Leukoencephalopathy, Renal Failure Acute, Rhabdomyolysis

An adverse event was reported by a consumer or non-health professional on Aug 20, 2009 by a Female taking Methadone (dosage: NA) . Location: , 56 years of age, patient began experiencing various side effects, including: Patient felt the following Methadone side effects: leukoencephalopathy, renal failure acute, rhabdomyolysis. Additional medications/treatments:
Multiple prescriptions taken:
  • Fentanyl
  • Benzodiazepines
The patient was hospitalized and became disabled.
Acute Respiratory Failure, Ischaemic Stroke, Renal Failure Acute, Rhabdomyolysis

This Rhabdomyolysis problem was reported by a consumer or non-health professional from . A 33-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Methadone Hcl (dosage: 150 Mg). The following drugs/medications were being taken at the same time:
  • Heroin
  • Naloxone
When commencing Methadone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Acute Respiratory Failure
  • Ischaemic Stroke
  • Renal Failure Acute
  • Rhabdomyolysis
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Rhabdomyolysis, may become evident only after a product is in use by the general population.
Blood Pressure Increased, Cyanosis, Hypoaesthesia, Pain, Peripheral Ischaemia, Rhabdomyolysis, Sinus Tachycardia

This is a Methadone Hcl side effect report of a 34-year-old patient (weight: NA) from . The patient developed the following symptoms/conditions: NA and was treated with Methadone Hcl (dosage: 100mg) starting NS. Concurrently used drugs:
  • Heparin
  • Heparin
  • Dextran Inj
  • Dexamethasone
  • Sodium Bicarbonate
  • Hydromorphone Hcl
  • Nifedipine
  • Coumadin
Soon after that, the consumer experienced the following of symptoms:
  • Blood Pressure Increased
  • Cyanosis
  • Hypoaesthesia
  • Pain
  • Peripheral Ischaemia
  • Rhabdomyolysis
  • Sinus Tachycardia
The patient was hospitalized. This opens a possibility that Methadone Hcl could cause Rhabdomyolysis and that some patients may be more susceptible.
Rhabdomyolysis, Therapeutic Agent Toxicity

This Rhabdomyolysis side effect was reported by a consumer or non-health professional from on Dec 15, 2008. A patient from , 30 years of age, was treated with Methadone Hcl. Patient felt the following Methadone side effects: rhabdomyolysis, therapeutic agent toxicity. Methadone Hcl dosage: NA. The patient was hospitalized. These side effects may potentially be related to Methadone Hcl.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methadone Rhabdomyolysis Causes and Reviews


Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that can affect muscles. Muscle disorders can cause weakness, pain or even paralysis.

Causes of muscle disorders include

  • Injury or overuse, such as sprains or strains, cramps or tendinitis
  • A genetic disorder, such as muscular dystrophy
  • Some cancers
  • Inflammation, such as myositis
  • Diseases of nerves that affect muscles
  • Infections
  • Certain medicines

Sometimes the cause is not known.


Methadone Rhabdomyolysis Reviews

Tue, 09 Feb 2010

good afternoon doc,my name dimasautisme,i comefrom indonesia ?
im Methadoners with 120 mg,im drink ARV to?please private my status?
i just want quesstion i want to detox,where i must go to hospital doc?
please help me :-D :)

Mon, 27 Dec 2010

I have been on Methadone for two years. Went fro
70 mgs a day to 20. I do for pain and I have been prescribed klonipin also recently for severe panic attacks and I read online that it's a deadly combo. I take my Methadone at 9 am. And have panic attacks around 10 pm every night before I sleep . Is this enough time apart to take them? Thank you

Thu, 31 Mar 2011
ive been takeing 90mls of Methadone for approxamitley 2 years on and off but properly this time for a total off 7 months i get servere sweating from taking my Methadone and feel very hot like im burning up and dripping with sweat why is this happening and what can i do and also im a type 2 diabetic and my Methadone is makeing my sugars drop really low what could be causing this and what can be done please help! thankyou katie .
Sat, 20 Aug 2011
Methodone Side Effects, I have had many trips to Emergency Unit at my Town, having tight painful heart problems. But when they do the Tests for Heart attacks, I jave always been told I have no problem my heart is fine. I have had ECG Tests, all fine. The only thing I can put it to ie: 250 milligrams of Methodone Tablet for Chronic Pain at the highest point was 50 x 5mg Tablest per day. I have had my leg amputated which I had the medication for. Can you confirm what I should be asking my GP, and what literature orResearch papers I can refer to. Thank you Geoff perry
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Toxicity To Various Agents (601)
Cardiac Arrest (334)
Respiratory Arrest (316)
Completed Suicide (256)
Overdose (197)
Death (147)
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Syncope (39)
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Sedation (36)
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Convulsion (31)
Hyperhidrosis (31)
Malaise (30)
Depressed Level Of Consciousness (30)
Coma (29)
Unresponsive To Stimuli (27)
Intentional Overdose (27)
Constipation (27)
Feeling Abnormal (26)
Hypokalaemia (26)
Pulmonary Congestion (26)
Renal Failure Acute (26)
Ventricular Tachycardia (25)
Headache (25)
Fatigue (25)
Brain Oedema (25)
Lethargy (24)
Rhabdomyolysis (24)
Respiratory Failure (24)
Incorrect Dose Administered (23)
Bradycardia (23)
Accidental Poisoning (23)
Miosis (22)

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