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Methotrexate Abdominal Pain Side Effects

Methotrexate Abdominal Pain Side Effect Reports


The following Methotrexate Abdominal Pain side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Abdominal Pain, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Disturbance In Attention, Headache, Abdominal Pain, Nausea

This Abdominal Pain side effect was reported by a health professional from PL. A 20-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methotrexate (dosage: 10 Mg, Qw), which was started on Dec 18, 2011. Concurrently used drugs: NA. When starting to take Methotrexate the consumer reported the following symptoms:
  • Disturbance In Attention
  • Headache
  • Abdominal Pain
  • Nausea
These side effects may potentially be related to Methotrexate.
Toxicity To Various Agents, Accidental Overdose, Stomatitis, Dysphagia, Diarrhoea, Abdominal Pain, Hypophagia, Skin Ulcer

This Abdominal Pain Methotrexate side effect was reported by a physician from DE on Jan 13, 2014. A Female , 71 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Toxicity To Various Agents
  • Accidental Overdose
  • Stomatitis
  • Dysphagia
  • Diarrhoea
  • Abdominal Pain
  • Hypophagia
  • Skin Ulcer
. Methotrexate dosage: NA. Additional drugs used at the same time: NA. The patient was hospitalized.
Abdominal Pain, Angioedema, Bronchospasm, Urticaria

This is a Methotrexate side effect report of a 57-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: rheumatoid arthritis, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
  • Leflunomide
  • Sulfasalazine
, and developed a serious reaction and a Abdominal Pain side effect. The patient presented with:
  • Abdominal Pain
  • Angioedema
  • Bronchospasm
  • Urticaria
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from rheumatoid arthritis, resulting in Abdominal Pain.

Urticaria, Angioedema, Throat Tightness, Abdominal Pain

A 57-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED with the following symptoms: rheumatoid arthritis started Methotrexate treatment (dosage: 20 Mg) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Urticaria
  • Angioedema
  • Throat Tightness
  • Abdominal Pain
. Concurrently used drugs:
  • Prednisone
This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Abdominal Pain.
Urticaria, Angioedema, Throat Tightness, Abdominal Pain

A female patient from AU was prescribed and started Methotrexate on Dec 17, 2013. Patient felt the following Methotrexate side effects: urticaria, angioedema, throat tightness, abdominal pain Additional patient health information: Female , 57 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: Adr Onset Following 20mg Dose. Concurrently used drugs:
  • Leflunomide
  • Sulfasalazine
  • Prednisone (15mg Daily)
The patient was hospitalized.
Cholestasis, Histoplasmosis Disseminated, Hepatic Infection Fungal, Malaise, Pyrexia, Weight Decreased, Night Sweats, Abdominal Pain

This report suggests a potential Methotrexate Abdominal Pain side effect(s) that can have serious consequences. A 74-year-old female patient from NL (weight:NA) was diagnosed with the following health condition(s): necrotising scleritis and used Methotrexate (dosage: 20 Mg, Per Week) starting 201104. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Cholestasis
  • Histoplasmosis Disseminated
  • Hepatic Infection Fungal
  • Malaise
  • Pyrexia
  • Weight Decreased
  • Night Sweats
  • Abdominal Pain
Drugs used concurrently:
  • Prednisolone (1 Mg/kg, Per Day)
  • Prednisolone (15 Mg, Per Day)
  • Adalimumab (40 Mg, Per Week)
The patient was hospitalized. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Abdominal Pain, may still occur.
Multi-organ Failure, Toxicity To Various Agents, Respiratory Failure, Renal Failure Acute, Septic Shock, Mucosal Inflammation, Pruritus, Abdominal Pain

An adverse event was reported by a health professional on Oct 28, 2013 by a Female taking Methotrexate (dosage: NA) was diagnosed with and. Location: IL , 75 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: multi-organ failure, toxicity to various agents, respiratory failure, renal failure acute, septic shock, mucosal inflammation, pruritus, abdominal pain. Additional medications/treatments:
Multi-organ Failure, Terminal State, Septic Shock, Respiratory Failure, Renal Failure Acute, Mucosal Inflammation, Abdominal Pain, Platelet Count Decreased, White Blood Cell Count Decreased

This Abdominal Pain problem was reported by a health professional from IL. A 75-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): rheumatoid arthritis.On NS a consumer started treatment with Methotrexate (dosage: 10 Mg, Qd Instead Of A Weekly Dose). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Multi-organ Failure
  • Terminal State
  • Septic Shock
  • Respiratory Failure
  • Renal Failure Acute
  • Mucosal Inflammation
  • Abdominal Pain
  • Platelet Count Decreased
  • White Blood Cell Count Decreased
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Abdominal Pain, may become evident only after a product is in use by the general population.
Toxicity To Various Agents, Respiratory Failure, Renal Failure Acute, Septic Shock, Multi-organ Failure, Pruritus, Mucosal Inflammation, Abdominal Pain

This is a Methotrexate side effect report of a 75-year-old female patient (weight: NA) from IL. The patient developed the following symptoms/conditions: rheumatoid arthritis and was treated with Methotrexate (dosage: NA) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Toxicity To Various Agents
  • Respiratory Failure
  • Renal Failure Acute
  • Septic Shock
  • Multi-organ Failure
  • Pruritus
  • Mucosal Inflammation
  • Abdominal Pain
This opens a possibility that Methotrexate could cause Abdominal Pain and that some female patients may be more susceptible.
Alveolitis Allergic, Dyspnoea Exertional, Cough, Abdominal Pain, Vomiting

This Abdominal Pain side effect was reported by a health professional from GB on Oct 02, 2013. A female patient from GB , 60 years of age, weighting 224.9 lb, was diagnosed with and was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: alveolitis allergic, dyspnoea exertional, cough, abdominal pain, vomiting. Methotrexate dosage: 25 Mg, Qw.
Associated medications used:
  • Tocilizumab (8 Mg/kg)
  • Leflunomide
  • Prednisolone
  • Folic Acid (5 Mg Qd)
  • Tramadol
  • Lansoprazole (15 Mg Qd)
  • Alendronic Acid (70 Mg Qw (take On Saturdays))
  • Citalopram (20 Mg Qd)
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Anxiety, Irritability, Palpitations, Hyperhidrosis, Vomiting, Abdominal Pain, Transaminases Increased

This Abdominal Pain side effect was reported by a health professional from PL. A 41-year-old patient (weight:NA) experienced the following symptoms/conditions: psoriasis. The patient was prescribed Methotrexate (dosage: 10 Mg, Per Week), which was started on 2013. Concurrently used drugs: NA. When starting to take Methotrexate the consumer reported the following symptoms:
  • Anxiety
  • Irritability
  • Palpitations
  • Hyperhidrosis
  • Vomiting
  • Abdominal Pain
  • Transaminases Increased
These side effects may potentially be related to Methotrexate.
Colitis, Abdominal Pain

This Abdominal Pain Methotrexate side effect was reported by a physician from COUNTRY NOT SPECIFIED on Jul 25, 2013. A male , 49 years of age, weighting 275.6 lb, was treated with Methotrexate. The patient presented the following health conditions:
  • Colitis
  • Abdominal Pain
. Methotrexate dosage: Day 1. Additional drugs used at the same time:
  • Rituxan (Day3)
The patient was hospitalized.
Renal Failure Acute, Tubulointerstitial Nephritis, White Blood Cell Count Increased, Abdominal Pain, Blood Creatine Increased

This is a Methotrexate side effect report of a 15-year-old patient (weight:NA) from GB, suffering from the following symptoms/conditions: anaplastic large-cell lymphoma,dyspepsia, who was treated with Methotrexate (dosage:3900 Milligram Daily;, start time: May 25, 2013), combined with:
  • Lansoprazole (30 Milligram Daily;)
  • Ondansetron
  • Levomepromazine
  • Paracetamol
  • Piperacillin And Tazobactam
  • Gentamicin
  • Codeine
  • Mesna
, and developed a serious reaction and a Abdominal Pain side effect. The patient presented with:
  • Renal Failure Acute
  • Tubulointerstitial Nephritis
  • White Blood Cell Count Increased
  • Abdominal Pain
  • Blood Creatine Increased
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in patients suffering from anaplastic large-cell lymphoma,dyspepsia, resulting in Abdominal Pain.
Tubulointerstitial Nephritis, White Blood Cell Count Increased, Renal Failure Acute, Blood Creatine Increased, Abdominal Pain

A 15-year-old patient (weight: NA) from GB with the following symptoms: anaplastic large-cell lymphoma,dyspepsia started Methotrexate treatment (dosage: 3900 Mg, Qd) on May 25, 2013. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Tubulointerstitial Nephritis
  • White Blood Cell Count Increased
  • Renal Failure Acute
  • Blood Creatine Increased
  • Abdominal Pain
. Concurrently used drugs:
  • Lansoprazole (30 Mg, Qd)
  • Ondansetron
  • Levomepromazine
  • Paracetamol
  • Piperacillin And Tazobactam
  • Gentamicin
  • Codeine
  • Mesna
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Abdominal Pain.
Urinary Tract Infection, Renal Cyst Haemorrhage, Pyelonephritis, Abscess, Infected Cyst, Diverticulitis, Malaise, Abdominal Pain, Decreased Appetite

A patient from US was prescribed and started Methotrexate on Jun 14, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: urinary tract infection, renal cyst haemorrhage, pyelonephritis, abscess, infected cyst, diverticulitis, malaise, abdominal pain, decreased appetite Additional patient health information: male , 71 years of age, weighting 164.0 lb, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: Chemo Every 2 Weeks. Concurrently used drugs:
  • Vinblastine
  • Doxorubicin
  • Cisplatin
  • Neulasta
The patient was hospitalized.
Abdominal Pain, Vomiting, Hypersensitivity

This report suggests a potential Methotrexate Abdominal Pain side effect(s) that can have serious consequences. A 38-year-old patient from US (weight:NA) was diagnosed with the following health condition(s): crohn^s disease and used Methotrexate (dosage: NA) starting Jan 05, 2010. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Abdominal Pain
  • Vomiting
  • Hypersensitivity
Drugs used concurrently:NA. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Abdominal Pain, may still occur.
Abdominal Pain, Diarrhoea, Vomiting

An adverse event was reported by a physician on Mar 06, 2013 by a male taking Methotrexate (dosage: NA) . Location: COUNTRY NOT SPECIFIED , weighting 31.39 lb, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: abdominal pain, diarrhoea, vomiting. Additional medications/treatments:
Multiple prescriptions taken:
  • Dexamethasone
  • Cytarabine
  • Oncaspar
  • Vincristine Sulfate
The patient was hospitalized.
Leukopenia, Diarrhoea, Liver Function Test Abnormal, Abdominal Pain

This Abdominal Pain problem was reported by a health professional from US. A 48-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): cutaneous sarcoidosis.On NS a consumer started treatment with Methotrexate (dosage: 15 Mg/week). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Leukopenia
  • Diarrhoea
  • Liver Function Test Abnormal
  • Abdominal Pain
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Abdominal Pain, may become evident only after a product is in use by the general population.
Leukopenia, Diarrhoea, Liver Function Test Abnormal, Abdominal Pain

This is a Methotrexate side effect report of a 48-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: cutaneous sarcoidosis and was treated with Methotrexate (dosage: 15 Mg/week) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Leukopenia
  • Diarrhoea
  • Liver Function Test Abnormal
  • Abdominal Pain
This opens a possibility that Methotrexate could cause Abdominal Pain and that some female patients may be more susceptible.
Hypophagia, Rectal Haemorrhage, Abdominal Pain, Chills, Diarrhoea, Dyspnoea Exertional, Febrile Neutropenia, Mouth Ulceration, Pancytopenia

This Abdominal Pain side effect was reported by a pharmacist from CA on Feb 15, 2013. A patient from CA , 66 years of age, weighting 178.6 lb, was treated with Methotrexate. Patient felt the following Methotrexate side effects: hypophagia, rectal haemorrhage, abdominal pain, chills, diarrhoea, dyspnoea exertional, febrile neutropenia, mouth ulceration, pancytopenia. Methotrexate dosage: 20 Milligram Daily;.
Multiple prescriptions taken:
  • Advair (Powder)
  • Amlodipine
  • Atorvastatin
  • Citalopram
  • Cozaar
  • Folic Acid
  • Furosemide
  • Rabeprazole
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Abdominal Pain Causes and Reviews


Your abdomen extends from below your chest to your groin. Some people call it the stomach, but your abdomen contains many other important organs. Pain in the abdomen can come from any one of them. The pain may start somewhere else, such as your chest. Severe pain doesn't always mean a serious problem. Nor does mild pain mean a problem is not serious.

Call your health care provider if mild pain lasts a week or more or if you have pain with other symptoms. Get medical help immediately if

  • You have abdominal pain that is sudden and sharp
  • You also have pain in your chest, neck or shoulder
  • You're vomiting blood or have blood in your stool
  • Your abdomen is stiff, hard and tender to touch
  • You can't move your bowels, especially if you're also vomiting

Methotrexate Abdominal Pain Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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