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Methotrexate Asthenia Side Effects

Methotrexate Asthenia Side Effect Reports


The following Methotrexate Asthenia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Asthenia, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Hyperhidrosis, Asthenia, Lung Disorder, Dyspnoea

This Asthenia side effect was reported by a consumer or non-health professional from US. A 59-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis. The patient was prescribed Methotrexate 2.5 (dosage: 2 Puffs Twice Daily At Bedtime), which was started on 201201. Concurrently used drugs:
  • Walker Seat
  • Wheelchair
  • Oxyen Tank
  • Pro Air Hfa - 90 Mcg Albuterol Per Actuation Manufactured In Ireland - Marketd By Teva
  • Cyclobenzaprine
  • Acetaminophen-oxycodone
  • Sulfamethoxzole
  • Prednisone
When starting to take Methotrexate 2.5 the consumer reported the following symptoms:
  • Hyperhidrosis
  • Asthenia
  • Lung Disorder
  • Dyspnoea
The patient was hospitalized and became disabled. These side effects may potentially be related to Methotrexate 2.5.
Dyspnoea, Asthenia, Deep Vein Thrombosis, Retroperitoneal Haemorrhage, Mental Status Changes, Sepsis, Shock Haemorrhagic, Metabolic Acidosis, Multi-organ Failure

This Asthenia Methotrexate side effect was reported by a physician from US on Mar 06, 2014. A Female , 60 years of age, weighting 272.9 lb, was treated with Methotrexate. The patient presented the following health conditions:
  • Dyspnoea
  • Asthenia
  • Deep Vein Thrombosis
  • Retroperitoneal Haemorrhage
  • Mental Status Changes
  • Sepsis
  • Shock Haemorrhagic
  • Metabolic Acidosis
  • Multi-organ Failure
. Methotrexate dosage: NA. Additional drugs used at the same time:
  • Procarbazine
  • Rituximab
The patient was hospitalized.
Fear Of Eating, Asthenia, Decreased Appetite, Nausea, Vomiting

This is a Methotrexate side effect report of a 55-year-old female patient (weight:NA) from PL, suffering from the following symptoms/conditions: psoriatic arthropathy, who was treated with Methotrexate (dosage:25 Mg, Unk, start time: Feb 02, 2013), combined with:
  • Acidum Folicum (15 Mg, Qw)
  • Metypred (8 Mg, Unk)
  • Ortanol (20 Mg, Unk)
  • Diaprel Mr (30 Mg, Unk)
  • Vitrum Calcium (1000 Mg, Unk)
, and developed a serious reaction and a Asthenia side effect. The patient presented with:
  • Fear Of Eating
  • Asthenia
  • Decreased Appetite
  • Nausea
  • Vomiting
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from psoriatic arthropathy, resulting in Asthenia.

Dyspnoea, Tachycardia, Hypotension, Asthenia, Deep Vein Thrombosis

A 60-year-old female patient (weight: NA) from US with the following symptoms: NA started Methotrexate treatment (dosage: NA) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Dyspnoea
  • Tachycardia
  • Hypotension
  • Asthenia
  • Deep Vein Thrombosis
. Concurrently used drugs:
  • Procarbazine
  • Rituximab
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Asthenia.
Nausea, Asthenia, Malaise

A female patient from PL was prescribed and started Methotrexate on Feb 03, 2014. Patient felt the following Methotrexate side effects: nausea, asthenia, malaise Additional patient health information: Female , weighting 121.3 lb, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 15 Mg, Qw. Concurrently used drugs:
  • Metypred (4 Mg, Qd)
  • Olfen (150 Mg, Qd)
  • Nolpaza (20 Mg, Qd)
Asthenia, Pancytopenia, Accidental Overdose, Renal Failure

This report suggests a potential Methotrexate Asthenia side effect(s) that can have serious consequences. A 82-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): osteoarthritis and used Methotrexate (dosage: 1 Pill, Qd, Oral) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Asthenia
  • Pancytopenia
  • Accidental Overdose
  • Renal Failure
Drugs used concurrently:NA. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Asthenia, may still occur.
Odynophagia, Oral Herpes, Pyrexia, Decreased Appetite, Asthenia, Stomatitis, Herpes Simplex Meningoencephalitis, Mental Status Changes, Mucosal Inflammation

An adverse event was reported by a pharmacist on Dec 02, 2013 by a male taking Methotrexate (dosage: 7.5 Mg, Qweek, Po) was diagnosed with and. Location: US , 67 years of age, weighting 210.5 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: odynophagia, oral herpes, pyrexia, decreased appetite, asthenia, stomatitis, herpes simplex meningoencephalitis, mental status changes, mucosal inflammation. Additional medications/treatments: The patient was hospitalized.
Presyncope, Asthenia, Oropharyngeal Pain, Dyspnoea, Productive Cough, Fall, Head Injury, Subdural Haematoma, Convulsion

This Asthenia problem was reported by a consumer or non-health professional from US. A 73-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time:
  • Procarbazine
  • Rituximab (moab C2b8 Anti Cd20, Chimeric)
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Presyncope
  • Asthenia
  • Oropharyngeal Pain
  • Dyspnoea
  • Productive Cough
  • Fall
  • Head Injury
  • Subdural Haematoma
  • Convulsion
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Asthenia, may become evident only after a product is in use by the general population.
Septic Shock, Colitis, Hypotension, Mental Status Changes, Nuclear Magnetic Resonance Imaging Brain Abnormal, Asthenia, Progressive Multifocal Leukoencephalopathy

This is a Methotrexate side effect report of a 12-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: acute lymphocytic leukaemia and was treated with Methotrexate (dosage: 15 Mg) starting Jul 10, 2013. Concurrently used drugs:
  • Epinephrine,
  • Norepinephrine,
  • Dobutamine,
  • Milrinone,
  • Vasopressin Infusions Vecuronium (changed To Cisatracurium),
  • Dexmedetomidine,
  • Midazolam Infusions
  • Hydrocortisone Ivp
Soon after that, the consumer experienced the following of symptoms:
  • Septic Shock
  • Colitis
  • Hypotension
  • Mental Status Changes
  • Nuclear Magnetic Resonance Imaging Brain Abnormal
  • Asthenia
  • Progressive Multifocal Leukoencephalopathy
The patient was hospitalized and became disabled. This opens a possibility that Methotrexate could cause Asthenia and that some female patients may be more susceptible.
Asthenia, Oropharyngeal Pain

This Asthenia side effect was reported by a health professional from PL on Aug 29, 2013. A female patient from PL , 76 years of age, weighting 165.3 lb, was diagnosed with and was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: asthenia, oropharyngeal pain. Methotrexate dosage: 15 Mg, Once/single. The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Pancytopenia, Dysphagia, Asthenia, Diarrhoea, Dehydration, Stomatitis

This Asthenia side effect was reported by a physician from TR. A 71-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis. The patient was prescribed Methotrexate (dosage: 2.5 Mg/day Three Days A Week), which was started on NS. Concurrently used drugs: NA. When starting to take Methotrexate the consumer reported the following symptoms:
  • Pancytopenia
  • Dysphagia
  • Asthenia
  • Diarrhoea
  • Dehydration
  • Stomatitis
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Dysphagia, Fatigue, Asthenia, Lip Erosion, Emotional Distress, Dehydration, Mouth Ulceration, Renal Failure Acute

This Asthenia Methotrexate side effect was reported by a health professional from US on Jun 11, 2013. A Female , 68 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Dysphagia
  • Fatigue
  • Asthenia
  • Lip Erosion
  • Emotional Distress
  • Dehydration
  • Mouth Ulceration
  • Renal Failure Acute
. Methotrexate dosage: 7.5 Mg, Qd. Additional drugs used at the same time: NA. The patient was hospitalized.
Nausea, Vomiting, Dizziness, Fatigue, Asthenia, Anaemia

This is a Methotrexate side effect report of a 77-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
  • Procarbazine
  • Rituximab (moab C2b8 Anti Cd20, Chimeric)
  • Vincristine Sulfate
, and developed a serious reaction and a Asthenia side effect. The patient presented with:
  • Nausea
  • Vomiting
  • Dizziness
  • Fatigue
  • Asthenia
  • Anaemia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from NA, resulting in Asthenia.
Influenza Like Illness, Asthenia, Contusion, Fatigue, Myalgia, Headache, Vision Blurred, Malaise

A 51-year-old female patient (weight: NA) from GB with the following symptoms: NA started Methotrexate treatment (dosage: NA) on Nov 28, 2012. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Influenza Like Illness
  • Asthenia
  • Contusion
  • Fatigue
  • Myalgia
  • Headache
  • Vision Blurred
  • Malaise
. Concurrently used drugs:
  • Trimethoprim
  • Aspirin
  • (limecycline)
  • Folic Acid
  • Beclometasone Dipropionate
  • Salbutamol
This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Asthenia.
Vision Blurred, Contusion, Malaise, Asthenia, Influenza Like Illness, Headache, Fatigue, Myalgia

A female patient from GB was prescribed and started Methotrexate on Feb 11, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: vision blurred, contusion, malaise, asthenia, influenza like illness, headache, fatigue, myalgia Additional patient health information: Female , 51 years of age, The consumer reported the following symptoms: . Methotrexate dosage: 30 Mg, Qw. Concurrently used drugs:
  • Trimethoprim
  • Aspirin
  • Lymecycline
  • Folic Acid
  • Clenil Modulite
  • Salbutamol
Asthenia, Malaise, Dysstasia, Fall, Dyspnoea, Lung Disorder, Pneumocystis Jirovecii Pneumonia, Tachycardia

This report suggests a potential Methotrexate Asthenia side effect(s) that can have serious consequences. A female patient from US (weight:NA) was diagnosed with the following health condition(s): corneal lesion and used Methotrexate (dosage: 10 Tablets 1 X Week Orally) starting Sep 20, 2012. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Asthenia
  • Malaise
  • Dysstasia
  • Fall
  • Dyspnoea
  • Lung Disorder
  • Pneumocystis Jirovecii Pneumonia
  • Tachycardia
Drugs used concurrently:NA. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Asthenia, may still occur.
Myalgia, Diabetes Mellitus Inadequate Control, Asthenia, Decreased Appetite

An adverse event was reported by a physician on Jan 28, 2013 by a Female taking Methotrexate (dosage: NA) was diagnosed with and. Location: DE , 79 years of age, weighting 132.3 lb, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: myalgia, diabetes mellitus inadequate control, asthenia, decreased appetite. Additional medications/treatments:
Asthenia, Headache, Vomiting, Decreased Appetite, Photophobia, Abdominal Pain Upper

This Asthenia problem was reported by a health professional from PL. A 27-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): psoriasis.On Jun 26, 2012 a consumer started treatment with Methotrexate (dosage: 15 Mg, Qw). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Asthenia
  • Headache
  • Vomiting
  • Decreased Appetite
  • Photophobia
  • Abdominal Pain Upper
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Asthenia, may become evident only after a product is in use by the general population.
Nausea, Abdominal Pain, Pallor, Asthenia, Cold Sweat, Wheelchair User

This is a Methotrexate side effect report of a patient (weight: NA) from US. The patient developed the following symptoms/conditions: juvenile rheumatoid arthritis and was treated with Methotrexate (dosage: Injectable Q Week Subcutaneous 057) starting Sep 28, 2012. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Nausea
  • Abdominal Pain
  • Pallor
  • Asthenia
  • Cold Sweat
  • Wheelchair User
This opens a possibility that Methotrexate could cause Asthenia and that some patients may be more susceptible.
Nausea, Abdominal Pain, Pallor, Asthenia, Cold Sweat

This Asthenia side effect was reported by a pharmacist from US on Dec 27, 2012. A patient from US , child 11 years of age, weighting 150.0 lb, was diagnosed with and was treated with Methotrexate. Patient felt the following Methotrexate side effects: nausea, abdominal pain, pallor, asthenia, cold sweat. Methotrexate dosage: NA.
Multiple prescriptions taken:
  • Prilosec
  • Celebrex
  • Pred
  • Tums
  • Benadryl
  • Multi Vit
  • Juice Plus
These side effects may potentially be related to Methotrexate.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Asthenia Causes and Reviews


We are sorry, but no medical information on this topic currently exists in our database. Our articles are updated often, please revisit soon.


Methotrexate Asthenia Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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