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Methotrexate Headache Side Effects

Methotrexate Headache Side Effect Reports


The following Methotrexate Headache side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Headache, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Nausea, Dizziness, Abdominal Discomfort, Arthralgia, Back Pain, Crying, Headache, Sensory Disturbance, Mood Swings

This Headache side effect was reported by a consumer or non-health professional from US. A 43-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methotrexate Sodium (dosage: NA), which was started on NS. Concurrently used drugs: NA. When starting to take Methotrexate Sodium the consumer reported the following symptoms:
  • Nausea
  • Dizziness
  • Abdominal Discomfort
  • Arthralgia
  • Back Pain
  • Crying
  • Headache
  • Sensory Disturbance
  • Mood Swings
These side effects may potentially be related to Methotrexate Sodium.
Headache

This Headache Methotrexate side effect was reported by a consumer or non-health professional from COUNTRY NOT SPECIFIED on Mar 04, 2014. A male , 54 years of age, was treated with Methotrexate. The patient presented the following health conditions:
  • Headache
. Methotrexate dosage: 2.5 Mg 4 Tabs Weekly. Additional drugs used at the same time:
  • Humira
  • Humira
  • Humira
Mucosal Inflammation, Toxicity To Various Agents, Headache

This is a Methotrexate side effect report of a 47-year-old female patient (weight:NA) from FR, suffering from the following symptoms/conditions: acute lymphocytic leukaemia, who was treated with Methotrexate (dosage:4.8 G, Unk, start time: NS), combined with:
  • Piperacillin+tazobactam
  • Folinic Acid (50 Mg, Qid)
  • Folinic Acid (200 Mg, Qid)
, and developed a serious reaction and a Headache side effect. The patient presented with:
  • Mucosal Inflammation
  • Toxicity To Various Agents
  • Headache
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from acute lymphocytic leukaemia, resulting in Headache.

Body Height Decreased, Tooth Loss, Incorrect Dose Administered, Eating Disorder, Limb Discomfort, Headache, Hip Arthroplasty, Bone Disorder

A 79-year-old female patient (weight: NA) from GB with the following symptoms: NA started Methotrexate treatment (dosage: NA) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Body Height Decreased
  • Tooth Loss
  • Incorrect Dose Administered
  • Eating Disorder
  • Limb Discomfort
  • Headache
  • Hip Arthroplasty
  • Bone Disorder
. Concurrently used drugs:
  • Livial (Gradually Come Off Livial.)
  • Vagifem
This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Headache.
Disturbance In Attention, Headache, Abdominal Pain, Nausea

A patient from PL was prescribed and started Methotrexate on Feb 01, 2014. Patient felt the following Methotrexate side effects: disturbance in attention, headache, abdominal pain, nausea Additional patient health information: male , 20 years of age, weighting 105.8 lb, The consumer reported the following symptoms: . Methotrexate dosage: 10 Mg, Qw. Concurrently used drugs: NA.
Genital Haemorrhage, Dizziness, Headache, Alopecia

This report suggests a potential Methotrexate Headache side effect(s) that can have serious consequences. A female patient from PL (weight:NA) was diagnosed with the following health condition(s): psoriasis and used Methotrexate (dosage: 10 Mg, Qw) starting Apr 25, 2013. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Genital Haemorrhage
  • Dizziness
  • Headache
  • Alopecia
Drugs used concurrently:NA. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Headache, may still occur.
Neurotoxicity, Headache, Dysphemia, Paraesthesia, Dyspnoea, Tremor, Bronchitis, Csf Protein Increased, Synovial Fluid Red Blood Cells Positive

An adverse event was reported by a physician on Jan 09, 2014 by a Female taking Methotrexate (dosage: 15 Mg, Per Week, Po) was diagnosed with and. Location: US , 57 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: neurotoxicity, headache, dysphemia, paraesthesia, dyspnoea, tremor, bronchitis, csf protein increased, synovial fluid red blood cells positive. Additional medications/treatments:
Associated medications used:
  • Adalimumab 40 Mg
Headache, Pneumonia, Muscular Weakness

This Headache problem was reported by a consumer or non-health professional from GB. A 85-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): ankylosing spondylitis.On Feb 18, 2010 a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Headache
  • Pneumonia
  • Muscular Weakness
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Pneumonia, Headache, Muscular Weakness

This is a Methotrexate side effect report of a 85-year-old female patient (weight: NA) from GB. The patient developed the following symptoms/conditions: ankylosing spondylitis and was treated with Methotrexate (dosage: NA) starting Feb 18, 2010. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Pneumonia
  • Headache
  • Muscular Weakness
The patient was hospitalized. This opens a possibility that Methotrexate could cause Headache and that some female patients may be more susceptible.
Headache, Muscular Weakness, Pneumonia

This Headache side effect was reported by a health professional from GB on Dec 26, 2013. A female patient from GB , 85 years of age, was diagnosed with and was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: headache, muscular weakness, pneumonia. Methotrexate dosage: 20 Mg, Unk. The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Temporal Lobe Epilepsy, Hippocampal Sclerosis, Grand Mal Convulsion, Nausea, Headache, Loss Of Consciousness

This Headache side effect was reported by a physician from US. A 6-year-old female patient (weight:NA) experienced the following symptoms/conditions: b precursor type acute leukaemia. The patient was prescribed Methotrexate (dosage: NA), which was started on NS. Concurrently used drugs:
  • Prednisone
  • Vincristine
  • 49-0-tetrahydropyranyladriamycin
  • L-asparaginase
When starting to take Methotrexate the consumer reported the following symptoms:
  • Temporal Lobe Epilepsy
  • Hippocampal Sclerosis
  • Grand Mal Convulsion
  • Nausea
  • Headache
  • Loss Of Consciousness
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Neurotoxicity, Headache, Dysphemia, Action Tremor, Paraesthesia, Bronchitis, Dyspnoea

This Headache Methotrexate side effect was reported by a physician from US on Dec 02, 2013. A Female , 57 years of age, was treated with Methotrexate. The patient presented the following health conditions:
  • Neurotoxicity
  • Headache
  • Dysphemia
  • Action Tremor
  • Paraesthesia
  • Bronchitis
  • Dyspnoea
. Methotrexate dosage: 15 Mg/week. Additional drugs used at the same time:
  • Adalimumab (40 Mg/week)
Stomatitis, Diarrhoea, Fatigue, Contusion, Yellow Skin, Pallor, Chest Pain, Headache, Chills

This is a Methotrexate side effect report of a 22-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: juvenile idiopathic arthritis, who was treated with Methotrexate (dosage:1 Pill Once A Week (saturday) Mouth, start time: 201305), combined with:
  • Mobic
, and developed a serious reaction and a Headache side effect. The patient presented with:
  • Stomatitis
  • Diarrhoea
  • Fatigue
  • Contusion
  • Yellow Skin
  • Pallor
  • Chest Pain
  • Headache
  • Chills
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in patients suffering from juvenile idiopathic arthritis, resulting in Headache.
Rheumatoid Arthritis, Hepatic Enzyme Increased, Injection Site Bruising, Blood Pressure Increased, Hot Flush, Headache, Arthralgia, Back Pain, Pain In Extremity

A 69-year-old female patient (weight: NA) from US with the following symptoms: rheumatoid arthritis started Methotrexate Sodium treatment (dosage: 2.5 Mg, 6 Tablets Weekly) on Jan 04, 2013. Soon after starting Methotrexate Sodium treatment, the consumer experienced several side effects, including:
  • Rheumatoid Arthritis
  • Hepatic Enzyme Increased
  • Injection Site Bruising
  • Blood Pressure Increased
  • Hot Flush
  • Headache
  • Arthralgia
  • Back Pain
  • Pain In Extremity
. Concurrently used drugs:
  • Ibuprofen (Unk)
  • Lipitor (40 Mg, Once Daily)
  • Humira (40 Mg, 1 In 2 Wk)
  • Furosemide (Unk)
  • Prednisone (5 Mg, Unk)
  • Prednisone (2.5 Mg, 1 In 1 D)
  • Folic Acid (1 Mg, 1 In 1 D)
  • Folic Acid
This finding indicates that some patients can be more vulnerable to developing Methotrexate Sodium side effects, such as Headache.
Headache, Eye Pain, Nausea, Product Substitution Issue

A female patient from US was prescribed and started Methotrexate on Aug 22, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: headache, eye pain, nausea, product substitution issue Additional patient health information: Female , 57 years of age, weighting 281.0 lb, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 8 Pills Once Weekly Taken By Mouth. Concurrently used drugs: NA.
Migraine, Cyst, Sinus Polyp, Headache, Epistaxis

This report suggests a potential Methotrexate Headache side effect(s) that can have serious consequences. A 12-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): juvenile idiopathic arthritis and used Methotrexate (dosage: NA) starting Nov 14, 2011. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Migraine
  • Cyst
  • Sinus Polyp
  • Headache
  • Epistaxis
Drugs used concurrently:
  • Prednisolone (prednisolone)
Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Headache, may still occur.
Migraine, Cyst, Sinus Polyp, Epistaxis, Headache

An adverse event was reported by a health professional on Mar 21, 2014 by a Female taking Methotrexate (dosage: 17.5 Mg, Unk) was diagnosed with and. Location: GB , child 12 years of age, weighting 157.4 lb, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: migraine, cyst, sinus polyp, epistaxis, headache. Additional medications/treatments:
Multiple prescriptions taken:
  • Prednisolone
Photophobia, Nausea, Vision Blurred, Headache

This Headache problem was reported by a health professional from US. A 11-year-old patient (weight: NA) was diagnosed with the following medical condition(s): non-hodgkin^s lymphoma.On NS a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time:
  • Vincristine
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Photophobia
  • Nausea
  • Vision Blurred
  • Headache
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Headache, Nausea, Photophobia, Vision Blurred, Optic Neuropathy

This is a Methotrexate side effect report of a 11-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Methotrexate (dosage: NA) starting NS. Concurrently used drugs:
  • Vincristine Sulfate
Soon after that, the consumer experienced the following of symptoms:
  • Headache
  • Nausea
  • Photophobia
  • Vision Blurred
  • Optic Neuropathy
This opens a possibility that Methotrexate could cause Headache and that some patients may be more susceptible.
Headache, Bone Pain, Photosensitivity Reaction

This Headache side effect was reported by a pharmacist from US on May 24, 2013. A female patient from US , 63 years of age, weighting 170.2 lb, was diagnosed with and was treated with Methotrexate. Patient felt the following Methotrexate side effects: headache, bone pain, photosensitivity reaction. Methotrexate dosage: NA. These side effects may potentially be related to Methotrexate.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Headache Causes and Reviews


Almost everyone has had a Headache. Headache is the most common form of pain. It's a major reason people miss days at work or school or visit the doctor.

The most common type of Headache is a tension Headache. Tension Headaches are due to tight muscles in your shoulders, neck, scalp and jaw. They are often related to stress, depression or anxiety. You are more likely to get tension Headaches if you work too much, don't get enough sleep, miss meals, or use alcohol.

Other common types of Headaches include migraines, cluster Headaches, and sinus Headaches. Most people can feel much better by making lifestyle changes, learning ways to relax and taking pain relievers.

Not all Headaches require a doctor's attention. But sometimes Headaches warn of a more serious disorder. Let your health care provider know if you have sudden, severe Headaches. Get medical help right away if you have a Headache after a blow to your head, or if you have a Headache along with a stiff neck, fever, confusion, loss of consciousness, or pain in the eye or ear.

NIH: National Institute of Neurological Disorders and Stroke


Methotrexate Headache Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Methotrexate Side Effects

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Renal Failure (118)
Hypertension (115)
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Nasopharyngitis (93)
Paraesthesia (93)
Septic Shock (91)

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