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Methotrexate Nausea Side Effects

Methotrexate Nausea Side Effect Reports


The following Methotrexate Nausea side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Nausea, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Nausea, Dizziness, Abdominal Discomfort, Arthralgia, Back Pain, Crying, Headache, Sensory Disturbance, Mood Swings

This Nausea side effect was reported by a consumer or non-health professional from US. A 43-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methotrexate Sodium (dosage: NA), which was started on NS. Concurrently used drugs: NA. When starting to take Methotrexate Sodium the consumer reported the following symptoms:
  • Nausea
  • Dizziness
  • Abdominal Discomfort
  • Arthralgia
  • Back Pain
  • Crying
  • Headache
  • Sensory Disturbance
  • Mood Swings
These side effects may potentially be related to Methotrexate Sodium.
Shoulder Arthroplasty, Nausea, Abdominal Discomfort

This Nausea Methotrexate side effect was reported by a consumer or non-health professional from US on Mar 06, 2014. A male , 59 years of age, weighting 219.8 lb, was treated with Methotrexate. The patient presented the following health conditions:
  • Shoulder Arthroplasty
  • Nausea
  • Abdominal Discomfort
. Methotrexate dosage: NA. Additional drugs used at the same time:
  • Enbrel
The patient was hospitalized.
Nausea, Dizziness, Malaise, Bronchitis, Cough, Dyspnoea, Pneumonia, Lung Disorder

This is a Methotrexate side effect report of a 67-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: palindromic rheumatism, who was treated with Methotrexate (dosage:5 Pills 2x/day Once A Week One Day Weekly, start time: Dec 03, 2012), combined with: NA., and developed a serious reaction and a Nausea side effect. The patient presented with:
  • Nausea
  • Dizziness
  • Malaise
  • Bronchitis
  • Cough
  • Dyspnoea
  • Pneumonia
  • Lung Disorder
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from palindromic rheumatism, resulting in Nausea.

Fear Of Eating, Asthenia, Decreased Appetite, Nausea, Vomiting

A 55-year-old female patient (weight: NA) from PL with the following symptoms: psoriatic arthropathy started Methotrexate treatment (dosage: 25 Mg, Unk) on Feb 02, 2013. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Fear Of Eating
  • Asthenia
  • Decreased Appetite
  • Nausea
  • Vomiting
. Concurrently used drugs:
  • Acidum Folicum (15 Mg, Qw)
  • Metypred (8 Mg, Unk)
  • Ortanol (20 Mg, Unk)
  • Diaprel Mr (30 Mg, Unk)
  • Vitrum Calcium (1000 Mg, Unk)
This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Nausea.
Gastrointestinal Disorder, Cholelithiasis, Gastritis, Weight Decreased, Duodenitis, Rheumatoid Arthritis, Iron Deficiency Anaemia, Nausea, Vomiting

A female patient from RS was prescribed and started Methotrexate on Feb 24, 2014. Patient felt the following Methotrexate side effects: gastrointestinal disorder, cholelithiasis, gastritis, weight decreased, duodenitis, rheumatoid arthritis, iron deficiency anaemia, nausea, vomiting Additional patient health information: Female , 63 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 7.5 Mg, Unk. Concurrently used drugs: NA. The patient was hospitalized.
Psoriasis, Pleural Effusion, Haemoglobin Decreased, Mouth Ulceration, Pericardial Effusion, Lower Respiratory Tract Infection, Systemic Lupus Erythematosus, Nausea

This report suggests a potential Methotrexate Nausea side effect(s) that can have serious consequences. A 35-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): NA and used Methotrexate (dosage: NA) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Psoriasis
  • Pleural Effusion
  • Haemoglobin Decreased
  • Mouth Ulceration
  • Pericardial Effusion
  • Lower Respiratory Tract Infection
  • Systemic Lupus Erythematosus
  • Nausea
Drugs used concurrently:
  • Ustekinumab
Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Nausea, Injection Site Pain

An adverse event was reported by a consumer or non-health professional on Feb 12, 2014 by a Female taking Methotrexate (dosage: 50mg/2ml-25mg/ml?once Per Week ?injection) was diagnosed with and. Location: US , 44 years of age, weighting 132.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: nausea, injection site pain. Additional medications/treatments:
Nausea, Asthenia, Malaise

This Nausea problem was reported by a health professional from PL. A female patient (weight: NA) was diagnosed with the following medical condition(s): rheumatoid arthritis.On Apr 15, 2011 a consumer started treatment with Methotrexate (dosage: 15 Mg, Qw). The following drugs/medications were being taken at the same time:
  • Metypred (4 Mg, Qd)
  • Olfen (150 Mg, Qd)
  • Nolpaza (20 Mg, Qd)
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Nausea
  • Asthenia
  • Malaise
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Nausea, may become evident only after a product is in use by the general population.
Disturbance In Attention, Headache, Abdominal Pain, Nausea

This is a Methotrexate side effect report of a 20-year-old patient (weight: NA) from PL. The patient developed the following symptoms/conditions: NA and was treated with Methotrexate (dosage: 10 Mg, Qw) starting Dec 18, 2011. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Disturbance In Attention
  • Headache
  • Abdominal Pain
  • Nausea
This opens a possibility that Methotrexate could cause Nausea and that some patients may be more susceptible.
Stomatitis, Pancytopenia, Renal Failure Acute, Dizziness, Nausea

This Nausea side effect was reported by a pharmacist from US on Jan 27, 2014. A patient from US , 91 years of age, was diagnosed with and was treated with Methotrexate 15 Mg. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: stomatitis, pancytopenia, renal failure acute, dizziness, nausea. Methotrexate 15 Mg dosage: NA. The patient was hospitalized. These side effects may potentially be related to Methotrexate 15 Mg.
Pulmonary Fibrosis, Nausea, Dyspnoea

This Nausea side effect was reported by a physician from DK. A 76-year-old patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis. The patient was prescribed Methotrexate (dosage: NA), which was started on Jan 10, 2007. Concurrently used drugs:
  • Humira
When starting to take Methotrexate the consumer reported the following symptoms:
  • Pulmonary Fibrosis
  • Nausea
  • Dyspnoea
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Temporal Lobe Epilepsy, Hippocampal Sclerosis, Grand Mal Convulsion, Nausea, Headache, Loss Of Consciousness

This Nausea Methotrexate side effect was reported by a physician from US on Dec 05, 2013. A Female , child 6 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Temporal Lobe Epilepsy
  • Hippocampal Sclerosis
  • Grand Mal Convulsion
  • Nausea
  • Headache
  • Loss Of Consciousness
. Methotrexate dosage: NA. Additional drugs used at the same time:
  • Prednisone
  • Vincristine
  • 49-0-tetrahydropyranyladriamycin
  • L-asparaginase
The patient was hospitalized.
Vaginal Haemorrhage, Hypovolaemic Shock, Renal Tubular Necrosis, Disseminated Intravascular Coagulation, Nausea, Gastritis

This is a Methotrexate side effect report of a 42-year-old female patient (weight:NA) from TH, suffering from the following symptoms/conditions: ectopic pregnancy, who was treated with Methotrexate (dosage:4 Doses, start time: NS), combined with:
  • Folinic Acid (5 Milligram Daily; 4 Doses)
  • Potassium Chloride
, and developed a serious reaction and a Nausea side effect. The patient presented with:
  • Vaginal Haemorrhage
  • Hypovolaemic Shock
  • Renal Tubular Necrosis
  • Disseminated Intravascular Coagulation
  • Nausea
  • Gastritis
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from ectopic pregnancy, resulting in Nausea.
Nausea, Decreased Appetite, Diarrhoea, Dry Skin, Contusion, Dyspnoea, Oral Fungal Infection, Speech Disorder, Abscess

A 61-year-old female patient (weight: NA) from US with the following symptoms: rheumatoid arthritis started Methotrexate treatment (dosage: 2.5 Mg, Take 7 Pills On Saturday. Po?once Week, On Saturday) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Nausea
  • Decreased Appetite
  • Diarrhoea
  • Dry Skin
  • Contusion
  • Dyspnoea
  • Oral Fungal Infection
  • Speech Disorder
  • Abscess
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Nausea.
Vaginal Haemorrhage, Hypovolaemic Shock, Renal Tubular Necrosis, Disseminated Intravascular Coagulation, Nausea, Gastritis

A female patient from TH was prescribed and started Methotrexate on Nov 25, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: vaginal haemorrhage, hypovolaemic shock, renal tubular necrosis, disseminated intravascular coagulation, nausea, gastritis Additional patient health information: Female , 42 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 50 Mg/m2 (4 Doses). Concurrently used drugs:
  • Folinic Acid (5mg Daily (4 Doses))
  • Potassium Chloride
The patient was hospitalized.
Serum Procollagen Type Iii N-terminal Propeptide Increased, Liver Function Test Abnormal, Quality Of Life Decreased, Nausea, Skin Fissures, Psoriasis, Disease Recurrence

This report suggests a potential Methotrexate Nausea side effect(s) that can have serious consequences. A 24-year-old patient from GB (weight:NA) was diagnosed with the following health condition(s): psoriasis and used Methotrexate (dosage: NA) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Serum Procollagen Type Iii N-terminal Propeptide Increased
  • Liver Function Test Abnormal
  • Quality Of Life Decreased
  • Nausea
  • Skin Fissures
  • Psoriasis
  • Disease Recurrence
Drugs used concurrently:
  • Infliximab (5 Mg/kg Milligram(s)/kilogram,)
Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Serum Procollagen Type Iii N-terminal Propeptide Increased, Liver Function Test Abnormal, Nausea, Quality Of Life Decreased, Skin Fissures, Psoriasis, Disease Recurrence

An adverse event was reported by a health professional on Dec 06, 2013 by a male taking Methotrexate (dosage: 1 In 1 Wk) was diagnosed with and. Location: GB , 24 years of age, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: serum procollagen type iii n-terminal propeptide increased, liver function test abnormal, nausea, quality of life decreased, skin fissures, psoriasis, disease recurrence. Additional medications/treatments:
Multiple prescriptions taken:
  • Remicade (5 Mg/kg, 1 In 8 Wk, Intravenous (not Otherwise Specified))
Toxicity To Various Agents, Psoriasis, Nausea, Vomiting

This Nausea problem was reported by a physician from US. A 90-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): psoriasis,pseudomonas infection.On NS a consumer started treatment with Methotrexate (dosage: 7.5 To 15 Mg Weekly). The following drugs/medications were being taken at the same time:
  • Ciprofloxacin
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Toxicity To Various Agents
  • Psoriasis
  • Nausea
  • Vomiting
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Nausea, may become evident only after a product is in use by the general population.
Off Label Use, Weight Increased, Psychotic Disorder, Hair Growth Abnormal, Nausea, Mouth Ulceration, Personality Change

This is a Methotrexate side effect report of a 39-year-old female patient (weight: NA) from GB. The patient developed the following symptoms/conditions: arthritis,affective disorder,bipolar disorder and was treated with Methotrexate (dosage: NA) starting NS. Concurrently used drugs:
  • Valproate Sodium/valproic Acid (ergenyl Chrono)
  • Valproate Sodium/valproic Acid (ergenyl Chrono)
  • Valproic Acid
Soon after that, the consumer experienced the following of symptoms:
  • Off Label Use
  • Weight Increased
  • Psychotic Disorder
  • Hair Growth Abnormal
  • Nausea
  • Mouth Ulceration
  • Personality Change
The patient was hospitalized. This opens a possibility that Methotrexate could cause Nausea and that some female patients may be more susceptible.
Acute Psychosis, Off Label Use, Nausea, Mouth Ulceration, Weight Increased, Hypertrichosis, Mental Disorder

This Nausea side effect was reported by a physician from GB on Nov 26, 2013. A female patient from GB , 39 years of age, weighting 132.3 lb, was diagnosed with and was treated with Methotrexate. Patient felt the following Methotrexate side effects: acute psychosis, off label use, nausea, mouth ulceration, weight increased, hypertrichosis, mental disorder. Methotrexate dosage: NA. The patient was hospitalized. These side effects may potentially be related to Methotrexate.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Nausea Causes and Reviews


Nausea is an uneasy or unsettled feeling in the stomach together with an urge to vomit. Nausea and vomiting, or throwing up, are not diseases. They can be symptoms of many different conditions. These include morning sickness during pregnancy, infections, migraine headaches, motion sickness, food poisoning, cancer chemotherapy or other medicines.

For vomiting in children and adults, avoid solid foods until vomiting has stopped for at least six hours. Then work back to a normal diet. Drink small amounts of clear liquids to avoid dehydration.

Nausea and vomiting are common. Usually, they are not serious. You should see a doctor immediately if you suspect poisoning or if you have

  • Vomited for longer than 24 hours
  • Blood in the vomit
  • Severe abdominal pain
  • Headache and stiff neck
  • Signs of dehydration, such as dry mouth, infrequent urination or dark urine

Methotrexate Nausea Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Pyrexia (411)
Pancytopenia (356)
Nausea (321)
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Rheumatoid Arthritis (260)
Dyspnoea (248)
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Rash (139)
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Hypertension (115)
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Hypotension (95)
Nasopharyngitis (93)
Paraesthesia (93)
Septic Shock (91)

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