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Methotrexate Neurotoxicity Side Effects

Methotrexate Neurotoxicity Side Effect Reports


The following Methotrexate Neurotoxicity side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Neurotoxicity, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Convulsion, Neurotoxicity

This Neurotoxicity side effect was reported by a pharmacist from US. A 5-year-old female patient (weight:NA) experienced the following symptoms/conditions: acute lymphocytic leukaemia. The patient was prescribed Methotrexate 12 Mg (dosage: 12 Mg Every 28 Days Intrathecal), which was started on Jan 31, 2014. Concurrently used drugs:
  • Vincristine
  • Mercaptopurine
  • Ondansetron
  • Dexamethasone
When starting to take Methotrexate 12 Mg the consumer reported the following symptoms:
  • Convulsion
  • Neurotoxicity
The patient was hospitalized. These side effects may potentially be related to Methotrexate 12 Mg.
Neurotoxicity, Headache, Dysphemia, Paraesthesia, Dyspnoea, Tremor, Bronchitis, Csf Protein Increased, Synovial Fluid Red Blood Cells Positive

This Neurotoxicity Methotrexate side effect was reported by a physician from US on Jan 09, 2014. A Female , 57 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Neurotoxicity
  • Headache
  • Dysphemia
  • Paraesthesia
  • Dyspnoea
  • Tremor
  • Bronchitis
  • Csf Protein Increased
  • Synovial Fluid Red Blood Cells Positive
. Methotrexate dosage: 15 Mg, Per Week, Po. Additional drugs used at the same time:
  • Adalimumab 40 Mg
Neurotoxicity, Bronchitis

This is a Methotrexate side effect report of a 57-year-old female patient (weight:NA) from COUNTRY NOT SPECIFIED, suffering from the following symptoms/conditions: rheumatoid arthritis, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
  • Adalimumab
, and developed a serious reaction and a Neurotoxicity side effect. The patient presented with:
  • Neurotoxicity
  • Bronchitis
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from rheumatoid arthritis, resulting in Neurotoxicity.

Neurotoxicity, Dysphemia, Fatigue

A 51-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED with the following symptoms: rheumatoid arthritis started Methotrexate treatment (dosage: NA) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Neurotoxicity
  • Dysphemia
  • Fatigue
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Neurotoxicity.
Neurotoxicity, Demyelinating Polyneuropathy

A patient from US was prescribed and started Methotrexate on Nov 27, 2013. Patient felt the following Methotrexate side effects: neurotoxicity, demyelinating polyneuropathy Additional patient health information: male , 35 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: NA. Concurrently used drugs: NA. The patient was hospitalized and became disabled.
Neurotoxicity, Dysphemia, Fatigue

This report suggests a potential Methotrexate Neurotoxicity side effect(s) that can have serious consequences. A 51-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): NA and used Methotrexate (dosage: 7.5mg Weekly, Then 25mg Weekly) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Neurotoxicity
  • Dysphemia
  • Fatigue
Drugs used concurrently:NA. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neurotoxicity, may still occur.
Neurotoxicity, Headache, Dysphemia, Action Tremor, Paraesthesia, Bronchitis, Dyspnoea

An adverse event was reported by a physician on Dec 02, 2013 by a Female taking Methotrexate (dosage: 15 Mg/week) . Location: US , 57 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: neurotoxicity, headache, dysphemia, action tremor, paraesthesia, bronchitis, dyspnoea. Additional medications/treatments:
Associated medications used:
  • Adalimumab (40 Mg/week)
Neurotoxicity, Convulsion

This Neurotoxicity problem was reported by a pharmacist from US. A 15-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): leukaemia.On Jun 13, 2013 a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Neurotoxicity
  • Convulsion
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Neurotoxicity, may become evident only after a product is in use by the general population.
Neurotoxicity, Convulsion

This is a Methotrexate side effect report of a female patient (weight: NA) from US. The patient developed the following symptoms/conditions: leukaemia and was treated with Methotrexate (dosage: NA) starting May 09, 2013. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Neurotoxicity
  • Convulsion
The patient was hospitalized. This opens a possibility that Methotrexate could cause Neurotoxicity and that some female patients may be more susceptible.
Neurotoxicity, Brain Oedema

This Neurotoxicity side effect was reported by a pharmacist from US on Aug 22, 2013. A female patient from US , child 4. years of age, weighting 66.14 lb, was diagnosed with and was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: neurotoxicity, brain oedema. Methotrexate dosage: Sdv. The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Neurotoxicity

This Neurotoxicity side effect was reported by a physician from US. A 15-year-old patient (weight:NA) experienced the following symptoms/conditions: leukaemia. The patient was prescribed Methotrexate (dosage: Sdv), which was started on May 09, 2013. Concurrently used drugs: NA. When starting to take Methotrexate the consumer reported the following symptoms:
  • Neurotoxicity
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Neurotoxicity

This Neurotoxicity Methotrexate side effect was reported by a pharmacist from US on Jul 03, 2013. A male , 15 years of age, weighting 176.4 lb, was treated with Methotrexate. The patient presented the following health conditions:
  • Neurotoxicity
. Methotrexate dosage: NA. Additional drugs used at the same time: NA.
Neurotoxicity, Convulsion

This is a Methotrexate side effect report of a female patient (weight:NA) from US, suffering from the following symptoms/conditions: leukaemia, who was treated with Methotrexate (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Neurotoxicity side effect. The patient presented with:
  • Neurotoxicity
  • Convulsion
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from leukaemia, resulting in Neurotoxicity.
Neurotoxicity

A 4-year-old female patient (weight: NA) from US with the following symptoms: NA started Methotrexate treatment (dosage: NA) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Neurotoxicity
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Neurotoxicity.
Neurotoxicity, Demyelination, Leukoencephalopathy, Gait Disturbance, Headache, Cerebellar Syndrome

A patient from ES was prescribed and started Methotrexate on Mar 06, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: neurotoxicity, demyelination, leukoencephalopathy, gait disturbance, headache, cerebellar syndrome Additional patient health information: male , child 4 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 5 Mg/m2, 2 Times. Concurrently used drugs: NA.
Neurotoxicity, Demyelination, Leukoencephalopathy, Somnolence, Aphasia, Hemiparesis

This report suggests a potential Methotrexate Neurotoxicity side effect(s) that can have serious consequences. A 14-year-old female patient from ES (weight:NA) was diagnosed with the following health condition(s): acute lymphocytic leukaemia and used Methotrexate (dosage: 3 Mg/m2, 2 Times) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Neurotoxicity
  • Demyelination
  • Leukoencephalopathy
  • Somnolence
  • Aphasia
  • Hemiparesis
Drugs used concurrently:NA. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neurotoxicity, may still occur.
Neurotoxicity, Demyelination, Leukoencephalopathy, Hemiparesis, Aphasia, Somnolence

An adverse event was reported by a health professional on Mar 06, 2013 by a male taking Methotrexate (dosage: 5 Mg/m2, 3 Times) was diagnosed with and. Location: ES , child 3 years of age, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: neurotoxicity, demyelination, leukoencephalopathy, hemiparesis, aphasia, somnolence. Additional medications/treatments:
Neurotoxicity, Demyelination, Leukoencephalopathy, Irritability, Hyperreflexia

This Neurotoxicity problem was reported by a health professional from ES. A 6-year-old patient (weight: NA) was diagnosed with the following medical condition(s): non-hodgkin^s lymphoma stage iv.On NS a consumer started treatment with Methotrexate (dosage: 5 Mg/m2, 4 Times). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Neurotoxicity
  • Demyelination
  • Leukoencephalopathy
  • Irritability
  • Hyperreflexia
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Neurotoxicity, may become evident only after a product is in use by the general population.
Neurotoxicity, Demyelination, Leukoencephalopathy, Ataxia, Dizziness, Hyperreflexia

This is a Methotrexate side effect report of a 2-year-old female patient (weight: NA) from ES. The patient developed the following symptoms/conditions: medulloblastoma and was treated with Methotrexate (dosage: 5 Mg/m2, 3 Times) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Neurotoxicity
  • Demyelination
  • Leukoencephalopathy
  • Ataxia
  • Dizziness
  • Hyperreflexia
This opens a possibility that Methotrexate could cause Neurotoxicity and that some female patients may be more susceptible.
Neurotoxicity, Demyelination, Leukoencephalopathy, Somnolence, Diplopia, Paresis Cranial Nerve

This Neurotoxicity side effect was reported by a health professional from ES on Mar 06, 2013. A patient from ES , child 4 years of age, was diagnosed with and was treated with Methotrexate. Patient felt the following Methotrexate side effects: neurotoxicity, demyelination, leukoencephalopathy, somnolence, diplopia, paresis cranial nerve. Methotrexate dosage: 3 Mg/m2, 3 Times. These side effects may potentially be related to Methotrexate.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Neurotoxicity Causes and Reviews


Methamphetamine - meth for short - is a very addictive stimulant drug. It is a powder that can be made into a pill or a shiny rock (called a crystal). The powder can be eaten or snorted up the nose. It can also be mixed with liquid and injected into your body with a needle. Crystal meth is smoked in a small glass pipe.

Meth at first causes a rush of good feelings, but then users feel edgy, overly excited, angry, or afraid. Meth use can quickly lead to addiction. It causes medical problems including

  • Making your body temperature so high that you pass out
  • Severe itching
  • "Meth mouth" - broken teeth and dry mouth
  • Thinking and emotional problems

NIH: National Institute on Drug Abuse


Methotrexate Neurotoxicity Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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