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Methotrexate Neutropenia Side Effects

Methotrexate Neutropenia Side Effect Reports


The following Methotrexate Neutropenia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Neutropenia, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Acute Myeloid Leukaemia, Thrombocytopenia, Neutropenia, Hypochromic Anaemia, Bone Marrow Failure, Spur Cell Anaemia, Dyspnoea

This Neutropenia side effect was reported by a health professional from US. A 65-year-old female patient (weight:NA) experienced the following symptoms/conditions: breast cancer. The patient was prescribed Methotrexate (dosage: 40 Mg/m2, Days 1 And 8), which was started on NS. Concurrently used drugs:
  • 5-fluorouracil (600 Mg/m2, Days 1 And 8)
  • Cyclophosphamide (100 Mg/m2, Unk)
When starting to take Methotrexate the consumer reported the following symptoms:
  • Acute Myeloid Leukaemia
  • Thrombocytopenia
  • Neutropenia
  • Hypochromic Anaemia
  • Bone Marrow Failure
  • Spur Cell Anaemia
  • Dyspnoea
These side effects may potentially be related to Methotrexate.
Acute Myeloid Leukaemia, Pancytopenia, Neutropenia, Poikilocytosis, Spur Cell Anaemia, Marrow Hyperplasia

This Neutropenia Methotrexate side effect was reported by a health professional from US on Feb 17, 2014. A Female , 65 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Acute Myeloid Leukaemia
  • Pancytopenia
  • Neutropenia
  • Poikilocytosis
  • Spur Cell Anaemia
  • Marrow Hyperplasia
. Methotrexate dosage: 40 Mg/m2, Days 1 And 8. Additional drugs used at the same time:
  • 5-fluorouracil (600 Mg/m2, Days 1 And 8)
  • Cyclophosphamide (100 Mg/m2, Unk)
  • Prednisone (60 Mg, 1-14 Days)
  • Tamoxifen (10 Mg, Bid)
Mucosal Inflammation, Neutropenia

This is a Methotrexate side effect report of a 56-year-old patient (weight:NA) from COUNTRY NOT SPECIFIED, suffering from the following symptoms/conditions: diffuse large b-cell lymphoma,central nervous system lymphoma, who was treated with Methotrexate (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Neutropenia side effect. The patient presented with:
  • Mucosal Inflammation
  • Neutropenia
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in patients suffering from diffuse large b-cell lymphoma,central nervous system lymphoma, resulting in Neutropenia.

Neutropenia, Overdose

A 86-year-old female patient (weight: NA) from NO with the following symptoms: rheumatoid arthritis started Methotrexate treatment (dosage: NA) on Oct 03, 2013. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Neutropenia
  • Overdose
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Neutropenia.
Neutropenic Sepsis, Mouth Ulceration, Oesophageal Ulcer, Neutropenia

A patient from GB was prescribed and started Methotrexate on Dec 27, 2013. Patient felt the following Methotrexate side effects: neutropenic sepsis, mouth ulceration, oesophageal ulcer, neutropenia Additional patient health information: male , 89 years of age, weighting 160.9 lb, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 20 Mg, Qw. Concurrently used drugs:
  • Perindopril
  • Omeprazole
  • Bendroflumethiazide
  • Venlafaxin
  • Prednisolon
  • Calcichew
  • Diamox
  • Folic Acid
Thrombocytopenia, Neutropenia, Mental Status Changes, Confusional State, Sepsis, Acute Respiratory Distress Syndrome, Supraventricular Tachycardia

This report suggests a potential Methotrexate Neutropenia side effect(s) that can have serious consequences. A 49-year-old patient from COUNTRY NOT SPECIFIED (weight:NA) was diagnosed with the following health condition(s): NA and used Methotrexate (dosage: NA) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Thrombocytopenia
  • Neutropenia
  • Mental Status Changes
  • Confusional State
  • Sepsis
  • Acute Respiratory Distress Syndrome
  • Supraventricular Tachycardia
Drugs used concurrently:
  • Rituximab
  • Temzolomide 315 Mg Abbott
The patient was hospitalized. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neutropenia, may still occur.
Lung Infection, Thrombocytopenia, Neutropenia, Sepsis, Mental Status Changes, Bacterial Infection, Localised Intraabdominal Fluid Collection

An adverse event was reported by a health professional on Sep 13, 2013 by a male taking Methotrexate (dosage: NA) . Location: US , weighting 249.1 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: lung infection, thrombocytopenia, neutropenia, sepsis, mental status changes, bacterial infection, localised intraabdominal fluid collection. Additional medications/treatments:
Associated medications used:
  • Rituximab (moab C2b8 Anti Cd20, Chimeric)
The patient was hospitalized.
Neutropenia, Stomatitis, Mucosal Inflammation, Agitation, Pain, Pancytopenia, Dystonia, Respiratory Distress, Otitis Media Acute

This Neutropenia problem was reported by a consumer or non-health professional from US. A patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Aug 16, 2013 a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time:
  • Lestaurtinib
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Neutropenia
  • Stomatitis
  • Mucosal Inflammation
  • Agitation
  • Pain
  • Pancytopenia
  • Dystonia
  • Respiratory Distress
  • Otitis Media Acute
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Neutropenia, may become evident only after a product is in use by the general population.
Pancytopenia, Neutropenia, Toxicity To Various Agents, Cystitis

This is a Methotrexate side effect report of a 79-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED. The patient developed the following symptoms/conditions: rheumatoid arthritis,cystitis and was treated with Methotrexate (dosage: NA) starting NS. Concurrently used drugs:
  • Trimethoprim-sulfamethoxazole
  • Folic Acid (5 Mg)
  • Asasantin Retard
  • Nifedipine
  • Escitalopram
  • Repaglinide
  • Bisoprolol
Soon after that, the consumer experienced the following of symptoms:
  • Pancytopenia
  • Neutropenia
  • Toxicity To Various Agents
  • Cystitis
The patient was hospitalized. This opens a possibility that Methotrexate could cause Neutropenia and that some female patients may be more susceptible.
Pancytopenia, Neutropenia, Toxicity To Various Agents, Cystitis

This Neutropenia side effect was reported by a health professional from COUNTRY NOT SPECIFIED on Aug 16, 2013. A female patient from COUNTRY NOT SPECIFIED , 79 years of age, was diagnosed with and was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: pancytopenia, neutropenia, toxicity to various agents, cystitis. Methotrexate dosage: NA.
Associated medications used:
  • Trimethoprim-sulfamethoxazole
  • Folic Acid (5 Mg)
  • Asasantin Retard
  • Nifedipine
  • Escitalopram
  • Repaglinide
  • Bisoprolol
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Neutropenia, Diverticular Perforation, Diverticulitis

This Neutropenia side effect was reported by a health professional from CH. A 70-year-old female patient (weight:NA) experienced the following symptoms/conditions: extranodal nk/t-cell lymphoma, nasal type. The patient was prescribed Methotrexate (dosage: NA), which was started on NS. Concurrently used drugs:
  • Etoposide
  • Dexamethasone
  • Ifosfamide
  • Asparaginase
When starting to take Methotrexate the consumer reported the following symptoms:
  • Neutropenia
  • Diverticular Perforation
  • Diverticulitis
These side effects may potentially be related to Methotrexate.
Neutropenia, Diverticulitis, Lymphocytosis, Multi-organ Failure

This Neutropenia Methotrexate side effect was reported by a health professional from CH on Jul 15, 2013. A Female , 70 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Neutropenia
  • Diverticulitis
  • Lymphocytosis
  • Multi-organ Failure
. Methotrexate dosage: NA. Additional drugs used at the same time:
  • Etoposide
  • Ifosfamide
  • Asparaginase
  • Dexamethasone
Multi-organ Failure, Diverticular Perforation, Diverticulitis, Neutropenia, Lymphocytosis

This is a Methotrexate side effect report of a 70-year-old female patient (weight:NA) from CH, suffering from the following symptoms/conditions: natural killer-cell lymphoblastic lymphoma, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
  • Dexamethasone
  • Etoposide
  • Asparaginase
  • Ifosfamide
, and developed a serious reaction and a Neutropenia side effect. The patient presented with:
  • Multi-organ Failure
  • Diverticular Perforation
  • Diverticulitis
  • Neutropenia
  • Lymphocytosis
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from natural killer-cell lymphoblastic lymphoma, resulting in Neutropenia.
Neutropenia

A 70-year-old female patient (weight: NA) from GB with the following symptoms: rheumatoid arthritis started Methotrexate treatment (dosage: Previosuly 15mg, Dose Reduced 2013) on 2012. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Neutropenia
. Concurrently used drugs:
  • Roactemra
  • Folic Acid (Reduced 2013 Previosuly 10mg)
  • Alendronic Acid
  • Calcium And Vitamin D
This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Neutropenia.
Neutropenia

A female patient from GB was prescribed and started Methotrexate on Oct 28, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: neutropenia Additional patient health information: Female , 70 years of age, weighting 121.3 lb, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 7.5 Mg, Qw. Concurrently used drugs:
  • Roactemra (400 Mg, Unk)
  • Folic Acid (5 Mg, Qw)
  • Alendronic Acid (70 Mg, Qw)
  • Calcium + Vit D
Neutropenia

This report suggests a potential Methotrexate Neutropenia side effect(s) that can have serious consequences. A 69-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): rheumatoid arthritis and used Methotrexate (dosage: 7.7 Mg, Qw) starting Apr 23, 2013. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Neutropenia
Drugs used concurrently:
  • Roactemra (580 Df, Unk)
  • Folic Acid (5 Mg, Qd)
  • Bendroflumethiazide (2.5 Mg, Qd)
  • Alendronic Acid (70 Mg, Unk)
  • Calcium + Vitamin D (2 Df, Unk)
  • Terazosin (2 Mg, Unk)
Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neutropenia, may still occur.
Immunosuppression, Anaemia, Neutropenia, Thrombocytopenia, Diarrhoea, Urinary Tract Infection, Arteriovenous Fistula Site Infection, Enterococcal Infection, Endocarditis

An adverse event was reported by a health professional on Jun 07, 2013 by a Female taking Methotrexate Sodium (dosage: 1g/m2; Total Dose 1600mg Over 2 Hours Every 2 Weeks) was diagnosed with and. Location: AU , 52 years of age, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: immunosuppression, anaemia, neutropenia, thrombocytopenia, diarrhoea, urinary tract infection, arteriovenous fistula site infection, enterococcal infection, endocarditis. Additional medications/treatments:
Multiple prescriptions taken:
  • Dexamethasone Sodium Phosphate
  • Cytarabine (100mg)
  • Rituximab (375 Mg/m2, Weekly X 8)
  • Leucovorin (60mg Iv 12 Hours After Mtx Infusion)
  • Leucovorin (50mg Iv Q6h X 2)
  • Leucovorin (200mg Iv Q4h X 12 Doses)
  • Leucovorin (50mg Iv Q6h X 15)
  • Leucovorin (200mg Iv Q6h X 10 Doses)
Pneumonia, Sepsis, Neutropenia, Acute Respiratory Failure, Lymphopenia

This Neutropenia problem was reported by a physician from ES. A 68-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): polymyalgia rheumatica,arteritis.On Jul 12, 2012 a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time:
  • Prednisone
  • Prednisone
  • Adiro
  • Adiro
  • Clopidogrel
  • Uniket
  • Natecal D
  • Risedronato Sodico
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Pneumonia
  • Sepsis
  • Neutropenia
  • Acute Respiratory Failure
  • Lymphopenia
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Neutropenia, may become evident only after a product is in use by the general population.
Neutropenia

This is a Methotrexate side effect report of a 70-year-old female patient (weight: NA) from GB. The patient developed the following symptoms/conditions: rheumatoid arthritis and was treated with Methotrexate (dosage: 15 Mg, Qw) starting 2011. Concurrently used drugs:
  • Roactemra (400 Mg)
  • Folic Acid (10 Mg, Qw)
  • Alendronic Acid (70 Mg, Qw)
  • Calcichew D3 (2 Df, Bid)
Soon after that, the consumer experienced the following of symptoms:
  • Neutropenia
This opens a possibility that Methotrexate could cause Neutropenia and that some female patients may be more susceptible.
Acute Respiratory Distress Syndrome, Cardiac Failure Congestive, Neutropenia, Infection, Ventricular Tachycardia, Blood Potassium Increased, Blood Magnesium Increased

This Neutropenia side effect was reported by a physician from JP on Apr 16, 2013. A patient from JP , 62 years of age, was diagnosed with and was treated with Methotrexate Sodium. Patient felt the following Methotrexate side effects: acute respiratory distress syndrome, cardiac failure congestive, neutropenia, infection, ventricular tachycardia, blood potassium increased, blood magnesium increased. Methotrexate Sodium dosage: NA.
Multiple prescriptions taken:
  • Cytarabine
These side effects may potentially be related to Methotrexate Sodium.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Neutropenia Causes and Reviews


Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Blood disorders affect one or more parts of the blood and prevent your blood from doing its job. They can be acute or chronic. Many blood disorders are inherited. Other causes include other diseases, side effects of medicines, and a lack of certain nutrients in your diet.

Types of blood disorders include

  • Platelet disorders, excessive clotting, and bleeding problems, which affect how your blood clots
  • Anemia, which happens when your blood does not carry enough oxygen to the rest of your body
  • Cancers of the blood, such as leukemia and myeloma
  • Eosinophilic disorders, which are problems with one type of white blood cell.

Methotrexate Neutropenia Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Paraesthesia (93)
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