sponsored
PatientsVille.com Logo

PatientsVille

Methotrexate Pancytopenia Side Effects

Methotrexate Pancytopenia Side Effect Reports


The following Methotrexate Pancytopenia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Pancytopenia, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Gastrointestinal Mucosal Necrosis, Oesophageal Stenosis, Large Intestinal Stenosis, Mucosal Inflammation, Pyrexia, Staphylococcal Infection, Pancytopenia

This Pancytopenia side effect was reported by a health professional from JP. A 82-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis. The patient was prescribed Methotrexate (dosage: 8mg/week), which was started on NS. Concurrently used drugs:
  • Loxoprofen (180mg/day)
  • Prednisolone (4-6mg/day)
When starting to take Methotrexate the consumer reported the following symptoms:
  • Gastrointestinal Mucosal Necrosis
  • Oesophageal Stenosis
  • Large Intestinal Stenosis
  • Mucosal Inflammation
  • Pyrexia
  • Staphylococcal Infection
  • Pancytopenia
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Pancytopenia, Hyperglycaemia, Diarrhoea, Renal Failure

This Pancytopenia Methotrexate side effect was reported by a physician from COUNTRY NOT SPECIFIED on Feb 28, 2014. A male , 75 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Pancytopenia
  • Hyperglycaemia
  • Diarrhoea
  • Renal Failure
. Methotrexate dosage: Dose- 40mg/mq. Additional drugs used at the same time:
  • Metforal (2000 Mg)
  • Zyloric (150 Mg)
The patient was hospitalized.
Hypokalaemia, Pancytopenia, Vomiting, Diarrhoea

This is a Methotrexate side effect report of a 50-year-old female patient (weight:NA) from FR, suffering from the following symptoms/conditions: b-cell lymphoma, who was treated with Methotrexate (dosage:NA, start time: Nov 18, 2013), combined with:
  • Cortancyl
  • Mabthera
  • Velcade
  • Doxorubicin
  • Endoxan
, and developed a serious reaction and a Pancytopenia side effect. The patient presented with:
  • Hypokalaemia
  • Pancytopenia
  • Vomiting
  • Diarrhoea
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from b-cell lymphoma, resulting in Pancytopenia.

Multi-organ Failure, Septic Shock, Condition Aggravated, Leukoencephalopathy, Aphasia, Mental Status Changes, Pyrexia, Pancytopenia, Faecal Incontinence

A 16-year-old female patient (weight: NA) from US with the following symptoms: acute lymphocytic leukaemia started Methotrexate treatment (dosage: 3 G/m2) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Multi-organ Failure
  • Septic Shock
  • Condition Aggravated
  • Leukoencephalopathy
  • Aphasia
  • Mental Status Changes
  • Pyrexia
  • Pancytopenia
  • Faecal Incontinence
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Pancytopenia.
Acute Myeloid Leukaemia, Pancytopenia, Neutropenia, Poikilocytosis, Spur Cell Anaemia, Marrow Hyperplasia

A female patient from US was prescribed and started Methotrexate on Feb 17, 2014. Patient felt the following Methotrexate side effects: acute myeloid leukaemia, pancytopenia, neutropenia, poikilocytosis, spur cell anaemia, marrow hyperplasia Additional patient health information: Female , 65 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: 40 Mg/m2, Days 1 And 8. Concurrently used drugs:
  • 5-fluorouracil (600 Mg/m2, Days 1 And 8)
  • Cyclophosphamide (100 Mg/m2, Unk)
  • Prednisone (60 Mg, 1-14 Days)
  • Tamoxifen (10 Mg, Bid)
Bone Tuberculosis, Hypercalcaemia, Pancytopenia, Renal Failure, Skin Necrosis

This report suggests a potential Methotrexate Pancytopenia side effect(s) that can have serious consequences. A 74-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): rheumatoid arthritis and used Methotrexate (dosage: NA) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Bone Tuberculosis
  • Hypercalcaemia
  • Pancytopenia
  • Renal Failure
  • Skin Necrosis
Drugs used concurrently:
  • Telmisartan (telmisartan)
  • Levothyroxine (levothyroxine)
The patient was hospitalized. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pancytopenia, may still occur.
Stomatitis, Pancytopenia, Renal Failure Acute, Dizziness, Nausea

An adverse event was reported by a pharmacist on Jan 27, 2014 by a male taking Methotrexate 15 Mg (dosage: NA) was diagnosed with and. Location: US , 91 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: stomatitis, pancytopenia, renal failure acute, dizziness, nausea. Additional medications/treatments: The patient was hospitalized.
Intervertebral Discitis, Bone Tuberculosis, Hypercalcaemia, Pancytopenia, Aspartate Aminotransferase Increased, Skin Necrosis, Renal Failure, Muscular Weakness

This Pancytopenia problem was reported by a health professional from TR. A 74-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): rheumatoid arthritis.On NS a consumer started treatment with Methotrexate (dosage: 1 Week). The following drugs/medications were being taken at the same time:
  • (fenyramidol)
  • (telmisartan)
  • (levothyroxine)
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Intervertebral Discitis
  • Bone Tuberculosis
  • Hypercalcaemia
  • Pancytopenia
  • Aspartate Aminotransferase Increased
  • Skin Necrosis
  • Renal Failure
  • Muscular Weakness
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Pancytopenia, may become evident only after a product is in use by the general population.
Pancytopenia, Renal Failure, Skin Necrosis, Hypercalcaemia, Bone Tuberculosis

This is a Methotrexate side effect report of a 74-year-old female patient (weight: NA) from TR. The patient developed the following symptoms/conditions: rheumatoid arthritis,hypertension,autoimmune thyroiditis and was treated with Methotrexate (dosage: 10 Milligram Daily;) starting NS. Concurrently used drugs:
  • Telmisartan (80 Milligram Daily;)
  • Levothyroxine Sodium (100 Milligram Daily;)
Soon after that, the consumer experienced the following of symptoms:
  • Pancytopenia
  • Renal Failure
  • Skin Necrosis
  • Hypercalcaemia
  • Bone Tuberculosis
The patient was hospitalized. This opens a possibility that Methotrexate could cause Pancytopenia and that some female patients may be more susceptible.
Polyarteritis Nodosa, Lumbar Vertebral Fracture, Hepatitis B, Pancytopenia, Liver Function Test Abnormal, Renal Impairment

This Pancytopenia side effect was reported by a health professional from COUNTRY NOT SPECIFIED on Jan 23, 2014. A female patient from COUNTRY NOT SPECIFIED , 60 years of age, was diagnosed with and was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: polyarteritis nodosa, lumbar vertebral fracture, hepatitis b, pancytopenia, liver function test abnormal, renal impairment. Methotrexate dosage: NA.
Associated medications used:
  • Azathioprine (100 Mg)
  • Methylprednisolone
  • Prednisolone (50 Mg)
  • Lamivudine (100 Mg)
  • Cyclosporine (100 Mg)
  • Adefovir (10 Mg)
  • Tacrolimus (2 Mg)
  • Colchicine (1.5 Mg)
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Bone Tuberculosis, Hypercalcaemia, Pancytopenia, Renal Failure

This Pancytopenia side effect was reported by a health professional from COUNTRY NOT SPECIFIED. A 74-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis,pain,hypertension,autoimmune thyroiditis. The patient was prescribed Methotrexate (dosage: NA), which was started on NS. Concurrently used drugs:
  • Phenyramidol Hydrochloride (200 Mg)
  • Telmisartan (80 Mg)
  • Levothyroxine (100 Mg)
When starting to take Methotrexate the consumer reported the following symptoms:
  • Bone Tuberculosis
  • Hypercalcaemia
  • Pancytopenia
  • Renal Failure
The patient was hospitalized. These side effects may potentially be related to Methotrexate.
Pancytopenia, Renal Failure, Skin Necrosis, Hypercalcaemia, Bone Tuberculosis

This Pancytopenia Methotrexate side effect was reported by a health professional from TR on Jan 20, 2014. A Female , 74 years of age, was diagnosed with and was treated with Methotrexate. The patient presented the following health conditions:
  • Pancytopenia
  • Renal Failure
  • Skin Necrosis
  • Hypercalcaemia
  • Bone Tuberculosis
. Methotrexate dosage: 10 Mg/week. Additional drugs used at the same time:
  • Telmisartan (80 Mg/day)
  • Levothyroxine Sodium (100 Mg/day)
The patient was hospitalized.
Thrombocytopenia, Pancytopenia

This is a Methotrexate side effect report of a 86-year-old female patient (weight:NA) from COUNTRY NOT SPECIFIED, suffering from the following symptoms/conditions: rheumatoid arthritis,urinary tract infection, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
  • Ciprofloxacin (1000 Mg)
  • Allopurinol
  • Alendronic Acid
  • Venlafaxine
, and developed a serious reaction and a Pancytopenia side effect. The patient presented with:
  • Thrombocytopenia
  • Pancytopenia
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from rheumatoid arthritis,urinary tract infection, resulting in Pancytopenia.
Hypercalcaemia, Pancytopenia, Muscular Weakness, Fatigue, Back Pain, Pyrexia, Bone Pain, Psoas Abscess, Bone Tuberculosis

A 74-year-old female patient (weight: NA) from TR with the following symptoms: rheumatoid arthritis,hypertension,autoimmune thyroiditis started Methotrexate treatment (dosage: 10 Mg, Per Week) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Hypercalcaemia
  • Pancytopenia
  • Muscular Weakness
  • Fatigue
  • Back Pain
  • Pyrexia
  • Bone Pain
  • Psoas Abscess
  • Bone Tuberculosis
. Concurrently used drugs:
  • Temisartan (80 Mg, Per Day)
  • Levothyroxine (100 Mg, Per Day)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Pancytopenia.
Toxicity To Various Agents, Clostridium Difficile Colitis, Pancytopenia, Macrocytosis, Mucocutaneous Ulceration, Perivascular Dermatitis, Bone Marrow Failure, Clostridium Test Positive

A female patient from US was prescribed and started Methotrexate on Jan 08, 2014. After Methotrexate was administered, patient encountered several Methotrexate side effects: toxicity to various agents, clostridium difficile colitis, pancytopenia, macrocytosis, mucocutaneous ulceration, perivascular dermatitis, bone marrow failure, clostridium test positive Additional patient health information: Female , 64 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: NA. Concurrently used drugs: NA. The patient was hospitalized.
Pancytopenia, Toxicity To Various Agents, Hypophagia, Fluid Intake Reduced, Renal Failure Acute, Acute Respiratory Failure, Pneumonia, Pneumonia Aspiration, Opportunistic Infection

This report suggests a potential Methotrexate Pancytopenia side effect(s) that can have serious consequences. A 84-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): rheumatoid arthritis and used Methotrexate (dosage: Q Saturday??chronic) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Pancytopenia
  • Toxicity To Various Agents
  • Hypophagia
  • Fluid Intake Reduced
  • Renal Failure Acute
  • Acute Respiratory Failure
  • Pneumonia
  • Pneumonia Aspiration
  • Opportunistic Infection
Drugs used concurrently:
  • Vit D
  • Zestril
  • Carvedilol
  • Singulair
  • Asa
The patient was hospitalized. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pancytopenia, may still occur.
Pancytopenia

An adverse event was reported by a health professional on Dec 24, 2013 by a Female taking Methotrexate (dosage: NA) was diagnosed with and. Location: IT , 86 years of age, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: pancytopenia. Additional medications/treatments:
Multiple prescriptions taken:
  • Ciprofloxacin
  • Allopurinol
  • Alendronic Acid
  • Venlafaxine
Clostridium Difficile Colitis, Perivascular Dermatitis, Pancytopenia, Macrocytosis, Bone Marrow Failure, Toxicity To Various Agents

This Pancytopenia problem was reported by a consumer or non-health professional from US. A 64-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Clostridium Difficile Colitis
  • Perivascular Dermatitis
  • Pancytopenia
  • Macrocytosis
  • Bone Marrow Failure
  • Toxicity To Various Agents
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Pancytopenia, may become evident only after a product is in use by the general population.
Clostridium Difficile Colitis, Bone Marrow Failure, Pancytopenia, Epidermal Necrosis, Toxicity To Various Agents, Perivascular Dermatitis

This is a Methotrexate side effect report of a 64-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Methotrexate (dosage: NA) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Clostridium Difficile Colitis
  • Bone Marrow Failure
  • Pancytopenia
  • Epidermal Necrosis
  • Toxicity To Various Agents
  • Perivascular Dermatitis
This opens a possibility that Methotrexate could cause Pancytopenia and that some female patients may be more susceptible.
Clostridium Difficile Colitis, Pancytopenia, Ulcer, Toxicity To Various Agents

This Pancytopenia side effect was reported by a health professional from US on Dec 06, 2013. A female patient from US , 64 years of age, was treated with Methotrexate. Patient felt the following Methotrexate side effects: clostridium difficile colitis, pancytopenia, ulcer, toxicity to various agents. Methotrexate dosage: NA. These side effects may potentially be related to Methotrexate.
1 of 17 

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Pancytopenia Causes and Reviews


If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute


Methotrexate Pancytopenia Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Common Drugs

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Top Methotrexate Side Effects

Pyrexia (411)
Pancytopenia (356)
Nausea (321)
Pneumonia (304)
Arthralgia (271)
Headache (269)
Injection Site Pain (265)
Rheumatoid Arthritis (260)
Dyspnoea (248)
Mucosal Inflammation (241)
Diarrhoea (238)
Vomiting (231)
Fatigue (223)
Asthenia (198)
Cough (196)
Sepsis (195)
Anaemia (195)
Pain (188)
Renal Failure Acute (177)
Malaise (156)
Febrile Neutropenia (152)
Abdominal Pain (152)
Injection Site Erythema (145)
Pain In Extremity (141)
Convulsion (139)
Rash (139)
Neurotoxicity (138)
Dizziness (131)
Neutropenia (129)
Condition Aggravated (129)
Thrombocytopenia (127)
Toxicity To Various Agents (125)
Oedema Peripheral (121)
Alanine Aminotransferase Increased (121)
Renal Failure (118)
Hypertension (115)
Weight Decreased (114)
Erythema (113)
Interstitial Lung Disease (113)
Stomatitis (108)
Respiratory Failure (108)
Bone Marrow Failure (108)
Leukopenia (104)
Fall (103)
Infection (103)
Aspartate Aminotransferase Increased (99)
Hypotension (95)
Nasopharyngitis (93)
Paraesthesia (93)
Septic Shock (91)

➢ More

Discuss Methotrexate Side Effects