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Methotrexate Paraesthesia Side Effects

Methotrexate Paraesthesia Side Effect Reports


The following Methotrexate Paraesthesia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Paraesthesia, can occur, and what you can do about them.

A side effect could appear soon after you start Methotrexate or it might take time to develop.



Neurotoxicity, Headache, Dysphemia, Paraesthesia, Dyspnoea, Tremor, Bronchitis, Csf Protein Increased, Synovial Fluid Red Blood Cells Positive

This Paraesthesia side effect was reported by a physician from US. A 57-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis. The patient was prescribed Methotrexate (dosage: 15 Mg, Per Week, Po), which was started on NS. Concurrently used drugs:
  • Adalimumab 40 Mg
When starting to take Methotrexate the consumer reported the following symptoms:
  • Neurotoxicity
  • Headache
  • Dysphemia
  • Paraesthesia
  • Dyspnoea
  • Tremor
  • Bronchitis
  • Csf Protein Increased
  • Synovial Fluid Red Blood Cells Positive
These side effects may potentially be related to Methotrexate.
Paraesthesia, Urticaria, Lip Swelling

This Paraesthesia Methotrexate side effect was reported by a consumer or non-health professional from US on Dec 31, 2013. A male , child 7. years of age, weighting 39.24 lb, was treated with Methotrexate. The patient presented the following health conditions:
  • Paraesthesia
  • Urticaria
  • Lip Swelling
. Methotrexate dosage: NA. Additional drugs used at the same time:
  • Prednisone
  • Vincristine Sulfate
The patient was hospitalized.
Guillain-barre Syndrome, Paresis, Paraesthesia, Quadriplegia, Dysphagia, Areflexia

This is a Methotrexate side effect report of a 35-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: acute myeloid leukaemia, who was treated with Methotrexate (dosage:Intrathecal, start time: NS), combined with: NA., and developed a serious reaction and a Paraesthesia side effect. The patient presented with:
  • Guillain-barre Syndrome
  • Paresis
  • Paraesthesia
  • Quadriplegia
  • Dysphagia
  • Areflexia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in patients suffering from acute myeloid leukaemia, resulting in Paraesthesia.

Neurotoxicity, Headache, Dysphemia, Action Tremor, Paraesthesia, Bronchitis, Dyspnoea

A 57-year-old female patient (weight: NA) from US with the following symptoms: NA started Methotrexate treatment (dosage: 15 Mg/week) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Neurotoxicity
  • Headache
  • Dysphemia
  • Action Tremor
  • Paraesthesia
  • Bronchitis
  • Dyspnoea
. Concurrently used drugs:
  • Adalimumab (40 Mg/week)
This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Paraesthesia.
Demyelinating Polyneuropathy, Paresis, Areflexia, Paraesthesia, Quadriplegia, Dysphagia

A patient from US was prescribed and started Methotrexate on Nov 15, 2013. Patient felt the following Methotrexate side effects: demyelinating polyneuropathy, paresis, areflexia, paraesthesia, quadriplegia, dysphagia Additional patient health information: male , 35 years of age, The consumer reported the following symptoms: was diagnosed with and. Methotrexate dosage: Unk. Concurrently used drugs: NA.
Pharyngeal Oedema, Paraesthesia Oral

This report suggests a potential Methotrexate Paraesthesia side effect(s) that can have serious consequences. A 41-year-old patient from GB (weight:NA) was diagnosed with the following health condition(s): sarcoidosis and used Methotrexate (dosage: 2.5 Mg) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
  • Pharyngeal Oedema
  • Paraesthesia Oral
Drugs used concurrently:NA. The patient was hospitalized. Although Methotrexate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Paraesthesia, may still occur.
Neurotoxicity, Headache, Paraesthesia, Dysphagia, Dysarthria, Blood Pressure Decreased, Heart Rate Increased, Viith Nerve Paralysis

An adverse event was reported by a physician on Jan 10, 2013 by a male taking Methotrexate (dosage: NA) was diagnosed with and. Location: US , 15 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: neurotoxicity, headache, paraesthesia, dysphagia, dysarthria, blood pressure decreased, heart rate increased, viith nerve paralysis. Additional medications/treatments:
Associated medications used:
  • Cyclophosphamide
  • Cytarabine
  • Mercaptopurine
  • Pegaspargase
  • Vincristine
The patient was hospitalized.
Neurotoxicity, Headache, Dysphagia, Dysarthria, Paraesthesia, Viith Nerve Paralysis, Hemiparesis

This Paraesthesia problem was reported by a physician from US. A 15-year-old patient (weight: NA) was diagnosed with the following medical condition(s): acute lymphocytic leukaemia.On NS a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time:
  • Cyclophosphamide
  • Cytarabine
  • Mercaptopurine
  • Vincristine
  • Pegaspargase
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Neurotoxicity
  • Headache
  • Dysphagia
  • Dysarthria
  • Paraesthesia
  • Viith Nerve Paralysis
  • Hemiparesis
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Paraesthesia, may become evident only after a product is in use by the general population.
Liver Injury, Anaemia, Tremor, Muscle Rigidity, Formication, Paraesthesia, Insomnia, Nervous System Disorder

This is a Methotrexate Sodium side effect report of a 59-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Methotrexate Sodium (dosage: Unk) starting NS. Concurrently used drugs:
  • Lyrica (75 Mg, 3x/day)
  • Cymbalta (60 Mg, 1x/day, In The Morning)
  • Cymbalta
  • Rituxan (Unk)
  • Aleve (Unk)
Soon after that, the consumer experienced the following of symptoms:
  • Liver Injury
  • Anaemia
  • Tremor
  • Muscle Rigidity
  • Formication
  • Paraesthesia
  • Insomnia
  • Nervous System Disorder
This opens a possibility that Methotrexate Sodium could cause Paraesthesia and that some female patients may be more susceptible.
Paraesthesia, Pulse Abnormal, Hypotension, Malaise, Infusion Related Reaction

This Paraesthesia side effect was reported by a physician from ITALY on May 31, 2012. A patient from ITALY , 66 years of age, was treated with Methotrexate. Directly after treatment started, patient experienced the unwanted or unexpected Methotrexate side effects: paraesthesia, pulse abnormal, hypotension, malaise, infusion related reaction. Methotrexate dosage: NA.
Associated medications used:
  • Nebivolol Hcl (Taken From 17 Years)
  • Omeprazole (Taken From 16 Years)
  • Remicade
  • Remicade
  • Leucovorin Calcium (Taken From 16 Years)
  • Aspirin (Taken From 17 Years)
  • Medrol (Taken From 16 Years)
These side effects may potentially be related to Methotrexate.
Weight Decreased, Paraesthesia

This Paraesthesia side effect was reported by a consumer or non-health professional from UNITED STATES. A 41-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Methotrexate (dosage: NA), which was started on May 01, 2012. Concurrently used drugs:
  • Enbrel (50 Mg, Qwk)
When starting to take Methotrexate the consumer reported the following symptoms:
  • Weight Decreased
  • Paraesthesia
These side effects may potentially be related to Methotrexate.
Stress, Joint Swelling, Paraesthesia, Rheumatoid Arthritis, Meniscus Lesion, Arthralgia

This Paraesthesia Methotrexate side effect was reported by a consumer or non-health professional from UNITED STATES on Apr 02, 2012. A Female , 56 years of age, was treated with Methotrexate. The patient presented the following health conditions:
  • Stress
  • Joint Swelling
  • Paraesthesia
  • Rheumatoid Arthritis
  • Meniscus Lesion
  • Arthralgia
. Methotrexate dosage: 6 Mg, Unk. Additional drugs used at the same time:
  • Enbrel (Unk)
  • Plaquenil (2 Mg, Unk)
Paraesthesia, Erythema, Rosacea, Pruritus

This is a Methotrexate side effect report of a 49-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
  • Prednisone Tab
  • Antibiotics
, and developed a serious reaction and a Paraesthesia side effect. The patient presented with:
  • Paraesthesia
  • Erythema
  • Rosacea
  • Pruritus
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Methotrexate treatment in female patients suffering from NA, resulting in Paraesthesia.
Back Pain, Cyst, Spinal Cord Compression, Muscular Weakness, Hypoaesthesia, Mass, Paralysis, Paraesthesia

A female patient (weight: NA) from UNITED STATES with the following symptoms: rheumatoid arthritis,cerebrovascular accident started Methotrexate treatment (dosage: NA) on Jan 01, 2012. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
  • Back Pain
  • Cyst
  • Spinal Cord Compression
  • Muscular Weakness
  • Hypoaesthesia
  • Mass
  • Paralysis
  • Paraesthesia
. Concurrently used drugs:
  • Plavix
  • Humira
  • Aspirin
  • Humira
  • Topamax
  • Januvia
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Methotrexate side effects, such as Paraesthesia.
Swollen Tongue, Dizziness, Paraesthesia, Hypersensitivity, Infusion Related Reaction, Herpes Simplex, Erythema

A female patient from UNITED STATES was prescribed and started Methotrexate on Mar 05, 2012. After Methotrexate was administered, patient encountered several Methotrexate side effects: swollen tongue, dizziness, paraesthesia, hypersensitivity, infusion related reaction, herpes simplex, erythema Additional patient health information: Female , weighting 186.0 lb, The consumer reported the following symptoms: . Methotrexate dosage: NA. Concurrently used drugs:
  • Vitamin D
  • Lisinopril
  • Remicade
  • Remicade
  • Remicade
Erythema, Nausea, Abdominal Discomfort, Headache, Pruritus, Paraesthesia, Fatigue, Rhinorrhoea, Burning Sensation

This report suggests a potential Methotrexate Sodium Paraesthesia side effect(s) that can have serious consequences. A 74-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Methotrexate Sodium (dosage: NA) starting Jul 25, 2011. Soon after starting Methotrexate Sodium the patient began experiencing various side effects, including:
  • Erythema
  • Nausea
  • Abdominal Discomfort
  • Headache
  • Pruritus
  • Paraesthesia
  • Fatigue
  • Rhinorrhoea
  • Burning Sensation
Drugs used concurrently:
  • Primidone
  • Meloxicam
  • Chlorzoxazone
  • Mvi (mvi) (vitamin Nos)
  • Hydroxychloroquine Sulfate
  • Reclast
  • Enablex (urinary Antispasmodisc) (darifenacin)
  • Nexium
Although Methotrexate Sodium demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Paraesthesia, may still occur.
Hemiparesis, Hypoaesthesia, Headache, Condition Aggravated, Hemiplegia, Neuropsychiatric Lupus, Paraesthesia, Convulsion, Mental Impairment

An adverse event was reported by a consumer or non-health professional on Feb 07, 2012 by a Female taking Methotrexate (dosage: NA) . Location: UNITED STATES , 27 years of age, weighting 89.00 lb, patient began experiencing various side effects, including: Patient felt the following Methotrexate side effects: hemiparesis, hypoaesthesia, headache, condition aggravated, hemiplegia, neuropsychiatric lupus, paraesthesia, convulsion, mental impairment. Additional medications/treatments:
Multiple prescriptions taken:
  • Plaquenil (hydroxychloroquine Sulfate0 (hydroxychloroquine Sulfate)
  • Prenisone (prednisone) (prednisone)
  • Benlysta (120 Mg, 1 In 28 D, Intravenous)
The patient was hospitalized.
Blister, Paraesthesia, Injection Site Haematoma, Increased Tendency To Bruise

This Paraesthesia problem was reported by a consumer or non-health professional from UNITED STATES. A 39-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Sep 16, 2011 a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time:
  • Humira (160mg Day 1, Then 80 Mg Day 15, Then 40 Mg Every Other Week)
  • Ciprofloxacin
  • Adderall 5 (For 6 Months)
  • Despriprine
When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
  • Blister
  • Paraesthesia
  • Injection Site Haematoma
  • Increased Tendency To Bruise
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Paraesthesia, may become evident only after a product is in use by the general population.
Hypoaesthesia, Paraesthesia, Rhinorrhoea

This is a Methotrexate side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Methotrexate (dosage: NA) starting Jun 01, 2011. Concurrently used drugs:
  • Plaquenil
  • Vitamin D
  • Acetaminophen
  • Metformin Hcl
  • Calcium
  • Humira
  • Requip
  • Folic Acid
Soon after that, the consumer experienced the following of symptoms:
  • Hypoaesthesia
  • Paraesthesia
  • Rhinorrhoea
This opens a possibility that Methotrexate could cause Paraesthesia and that some female patients may be more susceptible.
Device Malfunction, Pain, Incorrect Dose Administered, Paraesthesia

This Paraesthesia side effect was reported by a consumer or non-health professional from UNITED STATES on Jun 03, 2011. A female patient from UNITED STATES , 32 years of age, was diagnosed with and was treated with Methotrexate. Patient felt the following Methotrexate side effects: device malfunction, pain, incorrect dose administered, paraesthesia. Methotrexate dosage: NA.
Multiple prescriptions taken:
  • Folic Acid
  • Humira
  • Lexapro
These side effects may potentially be related to Methotrexate.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Methotrexate Paraesthesia Causes and Reviews


The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.

There are more than 600 neurologic diseases. Major types include

  • Diseases caused by faulty genes, such as Huntington's disease and muscular dystrophy
  • Problems with the way the nervous system develops, such as spina bifida
  • Degenerative diseases, where nerve cells are damaged or die, such as Parkinson's disease and Alzheimer's disease
  • Diseases of the blood vessels that supply the brain, such as stroke
  • Injuries to the spinal cord and brain
  • Seizure disorders, such as epilepsy
  • Cancer, such as brain tumors
  • infections, such as meningitis

Methotrexate Paraesthesia Reviews

Mon, 21 Feb 2011

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!

Sat, 26 Oct 2013

has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(

Sun, 15 May 2011

I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you

Sat, 20 Dec 2008
Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.
Sun, 24 Jan 2010
I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.
Tue, 27 Apr 2010
painful cough after 2 days of 1st dose lasting-- to date-- 6 days
Thu, 27 May 2010
I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.
Sat, 18 Sep 2010
im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Paraesthesia (93)
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