Methotrexate Respiratory Failure Side Effect Reports
The following Methotrexate Respiratory Failure side effect reports were submitted by healthcare professionals and consumers.
This information will help you understand how side effects, such as Respiratory Failure, can occur, and what you can do about them.
A side effect could appear soon after you start Methotrexate or it might take time to develop.
|Pneumonitis, Respiratory Failure|
This Respiratory Failure side effect was reported by a pharmacist from GB. A 68-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis. The patient was prescribed Methotrexate Sodium (dosage: Unk), which was started on Aug 16, 2013. Concurrently used drugs:
|Cardiovascular Insufficiency, Cardiac Arrest, Respiratory Failure, Dyspnoea, Face Oedema, C-reactive Protein Increased, Leukopenia, Thrombocytopenia|
This Respiratory Failure Methotrexate side effect was reported by a health professional from PL on Mar 03, 2014. A male , 49 years of age, was treated with Methotrexate. The patient presented the following health conditions:
|Foaming At Mouth, Dyskinesia, Status Epilepticus, Respiratory Failure, Convulsion, Hemiparesis, Oedema, Cerebral Haemorrhage, Leukaemia|
This is a Methotrexate side effect report of a 10-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Methotrexate (dosage:NA, start time: NS), combined with:
|Respiratory Failure, Interstitial Lung Disease, Cardiac Failure, Pyrexia, Jugular Vein Distension, C-reactive Protein Increased|
A 64-year-old patient (weight: NA) from COUNTRY NOT SPECIFIED with the following symptoms: psoriasis started Methotrexate treatment (dosage: NA) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
|Pulmonary Toxicity, Respiratory Failure, Pneumonitis|
A female patient from COUNTRY NOT SPECIFIED was prescribed and started Methotrexate on Dec 19, 2013. Patient felt the following Methotrexate side effects: pulmonary toxicity, respiratory failure, pneumonitis Additional patient health information: Female , 64 years of age, The consumer reported the following symptoms: was diagnosed with
|Multi-organ Failure, Toxicity To Various Agents, Respiratory Failure, Renal Failure Acute, Septic Shock, Mucosal Inflammation, Pruritus, Abdominal Pain|
This report suggests a potential Methotrexate Respiratory Failure side effect(s) that can have serious consequences. A 75-year-old female patient from IL (weight:NA) was diagnosed with the following health condition(s): rheumatoid arthritis and used Methotrexate (dosage: NA) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
|Multi-organ Failure, Terminal State, Septic Shock, Respiratory Failure, Renal Failure Acute, Mucosal Inflammation, Abdominal Pain, Platelet Count Decreased, White Blood Cell Count Decreased|
An adverse event was reported by a health professional on Oct 08, 2013 by a Female taking Methotrexate (dosage: 10 Mg, Qd Instead Of A Weekly Dose) was diagnosed with
|Toxicity To Various Agents, Respiratory Failure, Renal Failure Acute, Septic Shock, Multi-organ Failure, Pruritus, Mucosal Inflammation, Abdominal Pain|
This Respiratory Failure problem was reported by a health professional from IL. A 75-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): rheumatoid arthritis.On NS a consumer started treatment with Methotrexate (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
|Pulmonary Veno-occlusive Disease, Cytomegalovirus Infection, Mucosal Inflammation, Sepsis, Pulmonary Haemorrhage, Pneumonitis, Pulmonary Hypertension, Respiratory Failure, Idiopathic Pneumonia Syndrome|
This is a Methotrexate side effect report of a 8-year-old female patient (weight: NA) from GB. The patient developed the following symptoms/conditions: prophylaxis against graft versus host disease and was treated with Methotrexate (dosage: NA) starting NS. Concurrently used drugs:
|Pneumonia, Respiratory Failure, Interstitial Lung Disease, Pulmonary Toxicity|
This Respiratory Failure side effect was reported by a consumer or non-health professional from US on Jun 18, 2013. A female patient from US , 64 years of age, was diagnosed with
Associated medications used:
|Pulmonary Mycosis, Febrile Neutropenia, Respiratory Failure, Pleural Effusion, Platelet Count Decreased|
This Respiratory Failure side effect was reported by a physician from BR. A 17-year-old patient (weight:NA) experienced the following symptoms/conditions: burkitt^s lymphoma. The patient was prescribed Methotrexate (dosage: NA), which was started on NS. Concurrently used drugs:
|Pericardial Effusion, Cardiac Tamponade, Shock, Respiratory Failure, Pleural Effusion|
This Respiratory Failure Methotrexate side effect was reported by a health professional from COUNTRY NOT SPECIFIED on Apr 18, 2013. A Female , 38 years of age, was diagnosed with
|Encephalitis, Intracranial Pressure Increased, Respiratory Failure, Varicella, Varicella Zoster Pneumonia|
This is a Methotrexate side effect report of a 7.-year-old patient (weight:NA) from COUNTRY NOT SPECIFIED, suffering from the following symptoms/conditions: uveitis, who was treated with Methotrexate (dosage:7.5 Mg, Qw, start time: Oct 08, 2010), combined with:
|Neutropenia, Acute Respiratory Distress Syndrome, Immune Reconstitution Inflammatory Syndrome, Pneumocystis Jirovecii Pneumonia, Marrow Hyperplasia, Respiratory Failure|
A 51-year-old female patient (weight: NA) from US with the following symptoms: rheumatoid arthritis started Methotrexate treatment (dosage: NA) on NS. Soon after starting Methotrexate treatment, the consumer experienced several side effects, including:
A patient from US was prescribed and started Methotrexate on Feb 13, 2013. After Methotrexate was administered, patient encountered several Methotrexate side effects: respiratory failure Additional patient health information: male , 57 years of age, weighting 227.5 lb, The consumer reported the following symptoms: was diagnosed with
|Immune Reconstitution Inflammatory Syndrome, Pneumocystis Jirovecii Pneumonia, Respiratory Failure, Acute Respiratory Distress Syndrome, Neutropenia|
This report suggests a potential Methotrexate Respiratory Failure side effect(s) that can have serious consequences. A 51-year-old female patient from COUNTRY NOT SPECIFIED (weight:NA) was diagnosed with the following health condition(s): juvenile idiopathic arthritis and used Methotrexate (dosage: NA) starting NS. Soon after starting Methotrexate the patient began experiencing various side effects, including:
|Respiratory Failure, Pneumonia Viral, Bk Virus Infection, Dyspnoea, Viral Haemorrhagic Cystitis, Urinary Tract Obstruction, Haemorrhage Urinary Tract, Renal Impairment, Haematuria|
An adverse event was reported by a health professional on Jan 11, 2013 by a male taking Methotrexate (dosage: NA) was diagnosed with
Multiple prescriptions taken:
|Pneumonia, Septic Shock, Fatigue, Dyspnoea, Pyrexia, Respiratory Failure|
This Respiratory Failure problem was reported by a physician from TH. A 68-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): rheumatoid arthritis.On Mar 21, 2008 a consumer started treatment with Methotrexate (dosage: 1.0714 Milligram Daily;). The following drugs/medications were being taken at the same time: NA. When commencing Methotrexate, the patient experienced the following unwanted symptoms /side effects:
|Respiratory Failure, Sepsis, Hypotension, Pancytopenia, Intestinal Haemorrhage|
This is a Methotrexate side effect report of a 89-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED. The patient developed the following symptoms/conditions: NA and was treated with Methotrexate (dosage: 7.5 Mg) starting NS. Concurrently used drugs:
|Uterine Cancer, Respiratory Failure|
This Respiratory Failure side effect was reported by a physician from SE on Dec 11, 2013. A female patient from SE , 74 years of age, was diagnosed with
Methotrexate Respiratory Failure Causes and Reviews
What is respiratory failure?
Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.
When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.
Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.What causes respiratory failure?
Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include
- Lung diseases such as COPD (chronic obstructive pulmonary disease), cystic fibrosis, pneumonia, and pulmonary embolism
- Conditions that affect the nerves and muscles that control breathing, such as amyotrophic lateral sclerosis (ALS), muscular dystrophy, spinal cord injuries, and stroke
- Problems with the spine, such as scoliosis (a curve in the spine). They can affect the bones and muscles used for breathing.
- Damage to the tissues and ribs around the lungs. An injury to the chest can cause this damage.
- Drug or alcohol overdose
- Inhalation injuries, such as from inhaling smoke (from fires) or harmful fumes
The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.
A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.
Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.How is respiratory failure diagnosed?
Your health care provider will diagnose respiratory failure based on
- Your medical history
- A physical exam, which often includes
- Listening to your lungs to check for abnormal sounds
- Listening to your heart to check for arrhythmia
- Looking for a bluish color on your skin, lips, and fingernails
- Diagnostic tests, such as
- Pulse oximetry, a small sensor that uses a light to measure how much oxygen is in your blood. The sensor goes on the end of your finger or on your ear.
- Arterial blood gas test, a test that measures the oxygen and carbon dioxide levels in your blood. The blood sample is taken from an artery, usually in your wrist.
Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.What are the treatments for respiratory failure?
Treatment for respiratory failure depends on
- Whether it is acute (short-term) or chronic (ongoing)
- How severe it is
- What is causing it
Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.
One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include
- Oxygen therapy, through a nasal cannula (two small plastic tubes that go in your nostrils) or through a mask that fits over your nose and mouth
- Tracheostomy, a surgically-made hole that goes through the front of your neck and into your windpipe. A breathing tube, also called a tracheostomy, or trach tube, is placed in the hole to help you breathe.
- Ventilator, a breathing machine that blows air into your lungs. It also carries carbon dioxide out of your lungs.
- Other breathing treatments, such as noninvasive positive pressure ventilation (NPPV), which uses mild air pressure to keep your airways open while you sleep. Another treatment is a special bed that rocks back and forth, to help you breathe in and out.
- Fluids, often through an intravenous (IV), to improve blood flow throughout your body. They also provide nutrition.
- Medicines for discomfort
- Treatments for the cause of the respiratory failure. These treatments may include medicines and procedures.
If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.
If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.
Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.
NIH: National Heart, Lung, and Blood Institute
Methotrexate Respiratory Failure Reviews
|Mon, 21 Feb 2011|
My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it ultimately RA could be fatal. I am only in my 50's not ready to die yet!
|Sat, 26 Oct 2013|
has anybody had any positive affects from taking " Methoblastin " (Methotrexate) for psoaratic arthritis ? these reviews sound terrible and i have been told to go on it... im a little scared now :(
|Sun, 15 May 2011|
I have been on Methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is there anything I can do other than drink a lot of water. Thank you
|Sat, 20 Dec 2008|
|Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine again. I would want to know if I should reduce the dose.|
|Sun, 24 Jan 2010|
|I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause disseminated herpes which can be potentially fatal. My Rheum told me to take Benadryl. I believe this is going to be my one and only shot this drug scares the death out of me.|
|Tue, 27 Apr 2010|
|painful cough after 2 days of 1st dose lasting-- to date-- 6 days|
|Thu, 27 May 2010|
|I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spots, Stomach pains, reflux, Unable to properly swollow food, confussion, memmory loss, anxiety attacks, nightmares, hard on sleeping, high fevers, diahria, halusanations, itching, dry skin, mouth and eyes, coughin, sore tendons etc.. After i had stoped taking it, specialist said the side effects would go away. The side effects have never gone.. I try to controll it by taking Folic Acid 1mg a day, Glusamine (Joint food). 3 days a week i will take a small amount of Milk Thistle. Too much of Milk thistle would cause Mood swings and Constipation. Doctors are no help.|
|Sat, 18 Sep 2010|
|im a 44yrs old female who took Methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.|