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Mirtazapine Neuroleptic Malignant Syndrome Side Effects

Mirtazapine Neuroleptic Malignant Syndrome Side Effect Reports


The following Mirtazapine Neuroleptic Malignant Syndrome side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Neuroleptic Malignant Syndrome, can occur, and what you can do about them.

A side effect could appear soon after you start Mirtazapine or it might take time to develop.



Neuroleptic Malignant Syndrome

This Neuroleptic Malignant Syndrome side effect was reported by a health professional from AU. A 65-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Mirtazapine (dosage: NA), which was started on NS. Concurrently used drugs:
  • Olanzapine
  • Arginine Hydrochloride (arginine Hydrochloride)
  • Aspirin (acetylsalicylic Acid)
  • Atorvastatin (atovastatin)
  • Colecalciferol (colecalciferol)
  • Ezetimibe (ezetimibe) (tablet)
  • Metformin Hydrochloride (metformin Hydrochloride)
When starting to take Mirtazapine the consumer reported the following symptoms:
  • Neuroleptic Malignant Syndrome
The patient was hospitalized. These side effects may potentially be related to Mirtazapine.
Dehydration, Neuroleptic Malignant Syndrome, Paralysis, Cholecystitis, Coma, Sedation, Cystitis Escherichia, Catatonia, Urinary Tract Infection

This Neuroleptic Malignant Syndrome Mirtazapine (mirtazapine) side effect was reported by a consumer or non-health professional from GB on Mar 28, 2013. A Female , 70 years of age, weighting 182.1 lb, was treated with Mirtazapine (mirtazapine). The patient presented the following health conditions:
  • Dehydration
  • Neuroleptic Malignant Syndrome
  • Paralysis
  • Cholecystitis
  • Coma
  • Sedation
  • Cystitis Escherichia
  • Catatonia
  • Urinary Tract Infection
. Mirtazapine (mirtazapine) dosage: NA. Additional drugs used at the same time:
  • Risperidone (risperidone)
  • Diazepam (diazepam)
The patient was hospitalized.
Neuroleptic Malignant Syndrome

This is a Mirtazapine side effect report of a 70-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: NA, who was treated with Mirtazapine (dosage:NA, start time: NS), combined with:
  • Risperidone
  • Diazepam
, and developed a serious reaction and a Neuroleptic Malignant Syndrome side effect. The patient presented with:
  • Neuroleptic Malignant Syndrome
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Mirtazapine treatment in female patients suffering from NA, resulting in Neuroleptic Malignant Syndrome.

Neuroleptic Malignant Syndrome, Catatonia, Urinary Tract Infection, Bedridden, Cholecystitis, Coma, Dehydration, Pyrexia

A 70-year-old female patient (weight: NA) from GB with the following symptoms: NA started Mirtazapine treatment (dosage: NA) on NS. Soon after starting Mirtazapine treatment, the consumer experienced several side effects, including:
  • Neuroleptic Malignant Syndrome
  • Catatonia
  • Urinary Tract Infection
  • Bedridden
  • Cholecystitis
  • Coma
  • Dehydration
  • Pyrexia
. Concurrently used drugs:
  • Diazepam
  • Risperidone
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Mirtazapine side effects, such as Neuroleptic Malignant Syndrome.
Neuroleptic Malignant Syndrome, Confusional State, Agitation, Convulsion, Blood Lactic Acid Increased, Encephalopathy, Blood Creatine Phosphokinase Increased, Csf Protein Increased, Encephalitis

A patient from GB was prescribed and started Mirtazapine on Feb 11, 2013. Patient felt the following Mirtazapine side effects: neuroleptic malignant syndrome, confusional state, agitation, convulsion, blood lactic acid increased, encephalopathy, blood creatine phosphokinase increased, csf protein increased, encephalitis Additional patient health information: male , 51 years of age, The consumer reported the following symptoms: was diagnosed with and. Mirtazapine dosage: NA. Concurrently used drugs:
  • Simvastatin
  • Metformin
  • Glimepiride
The patient was hospitalized.
Agitation, Csf Protein Increased, Confusional State, Blood Creatine Phosphokinase Increased, Encephalitis, Encephalopathy, Blood Lactic Acid Increased, Neuroleptic Malignant Syndrome, Convulsion

This report suggests a potential Mirtazapine Neuroleptic Malignant Syndrome side effect(s) that can have serious consequences. A 51-year-old patient from GB (weight:NA) was diagnosed with the following health condition(s): depression and used Mirtazapine (dosage: 30 Mg, Unk) starting NS. Soon after starting Mirtazapine the patient began experiencing various side effects, including:
  • Agitation
  • Csf Protein Increased
  • Confusional State
  • Blood Creatine Phosphokinase Increased
  • Encephalitis
  • Encephalopathy
  • Blood Lactic Acid Increased
  • Neuroleptic Malignant Syndrome
  • Convulsion
Drugs used concurrently:
  • Glimepiride
  • Metformin
  • Simvastatin
The patient was hospitalized. Although Mirtazapine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neuroleptic Malignant Syndrome, may still occur.
Agitation, Csf Protein Increased, Confusional State, Blood Creatine Phosphokinase Increased, Encephalitis, Encephalopathy, Blood Lactic Acid Increased, Neuroleptic Malignant Syndrome, Convulsion

An adverse event was reported by a pharmacist on Feb 21, 2013 by a male taking Mirtazapine (dosage: 30 Mg, Unk) was diagnosed with and. Location: GB , 51 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Mirtazapine side effects: agitation, csf protein increased, confusional state, blood creatine phosphokinase increased, encephalitis, encephalopathy, blood lactic acid increased, neuroleptic malignant syndrome, convulsion. Additional medications/treatments:
Associated medications used:
  • Glimepiride
  • Metformin
  • Simvastatin
The patient was hospitalized.
Agitation, Confusional State, Convulsion, Encephalitis, Encephalopathy, Neuroleptic Malignant Syndrome, Blood Lactic Acid Increased

This Neuroleptic Malignant Syndrome problem was reported by a pharmacist from COUNTRY NOT SPECIFIED. A 51-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Mirtazapine (mirtazapine) (dosage: (30 Mg),oral). The following drugs/medications were being taken at the same time:
  • Glimepiride (glimepiride)
  • Metformin Hydrochloride
  • Simvastatin
When commencing Mirtazapine (mirtazapine), the patient experienced the following unwanted symptoms /side effects:
  • Agitation
  • Confusional State
  • Convulsion
  • Encephalitis
  • Encephalopathy
  • Neuroleptic Malignant Syndrome
  • Blood Lactic Acid Increased
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Neuroleptic Malignant Syndrome, may become evident only after a product is in use by the general population.
Confusional State, Agitation, Convulsion, Encephalitis, Neuroleptic Malignant Syndrome

This is a Mirtazapine side effect report of a 51-year-old patient (weight: NA) from DK. The patient developed the following symptoms/conditions: NA and was treated with Mirtazapine (dosage: 30 Mg, Po) starting NS. Concurrently used drugs:
  • Simvastatin
  • Metformin Hydrochloride
  • Glimepiride
Soon after that, the consumer experienced the following of symptoms:
  • Confusional State
  • Agitation
  • Convulsion
  • Encephalitis
  • Neuroleptic Malignant Syndrome
The patient was hospitalized. This opens a possibility that Mirtazapine could cause Neuroleptic Malignant Syndrome and that some patients may be more susceptible.
Neuroleptic Malignant Syndrome, Agitation, Confusional State, Convulsion, Csf Protein Increased, Encephalitis, Encephalopathy, Blood Lactic Acid Increased

This Neuroleptic Malignant Syndrome side effect was reported by a pharmacist from GB on Oct 01, 2012. A patient from GB , 51 years of age, was diagnosed with and was treated with Mirtazapine. Directly after treatment started, patient experienced the unwanted or unexpected Mirtazapine side effects: neuroleptic malignant syndrome, agitation, confusional state, convulsion, csf protein increased, encephalitis, encephalopathy, blood lactic acid increased. Mirtazapine dosage: NA.
Associated medications used:
  • Glimepiride
  • Metformin
  • Simvastatin
The patient was hospitalized. These side effects may potentially be related to Mirtazapine.
Encephalitis, Encephalopathy, Csf Protein Increased, Blood Lactic Acid Increased, Neuroleptic Malignant Syndrome, Blood Creatine Phosphokinase Increased, Confusional State, Agitation, Convulsion

This Neuroleptic Malignant Syndrome side effect was reported by a health professional from GB. A 51-year-old patient (weight:NA) experienced the following symptoms/conditions: depression. The patient was prescribed Mirtazapine (dosage: 30 Mg), which was started on NS. Concurrently used drugs:
  • Glimepiride
  • Metformin
  • Simvastatin
When starting to take Mirtazapine the consumer reported the following symptoms:
  • Encephalitis
  • Encephalopathy
  • Csf Protein Increased
  • Blood Lactic Acid Increased
  • Neuroleptic Malignant Syndrome
  • Blood Creatine Phosphokinase Increased
  • Confusional State
  • Agitation
  • Convulsion
The patient was hospitalized. These side effects may potentially be related to Mirtazapine.
Muscle Rigidity, Neuroleptic Malignant Syndrome, Serotonin Syndrome, Bedridden, Labile Blood Pressure, Hyperthermia, Loss Of Consciousness, Hypertonia

This Neuroleptic Malignant Syndrome Mirtazapine side effect was reported by a physician from on May 25, 2012. A Female , 44 years of age, was diagnosed with and was treated with Mirtazapine. The patient presented the following health conditions:
  • Muscle Rigidity
  • Neuroleptic Malignant Syndrome
  • Serotonin Syndrome
  • Bedridden
  • Labile Blood Pressure
  • Hyperthermia
  • Loss Of Consciousness
  • Hypertonia
. Mirtazapine dosage: 180 Mg (45 Mg, 4 In 1 D), Oral. Additional drugs used at the same time: NA. The patient was hospitalized and became disabled.
Psychomotor Retardation, Hyperthermia, Neuroleptic Malignant Syndrome, Serotonin Syndrome, Blood Pressure Fluctuation, Nuchal Rigidity, Hypertonia, Muscle Rigidity, Hyperhidrosis

This is a Mirtazapine side effect report of a 44-year-old female patient (weight:NA) from , suffering from the following symptoms/conditions: depression,bipolar disorder, who was treated with Mirtazapine (dosage:180 Mg (45 Mg, 4 In 1 D), Oral, start time: Nov 02, 2007), combined with:
  • Risperidone ((62.5 Mg, 1 Wk))
, and developed a serious reaction and a Neuroleptic Malignant Syndrome side effect. The patient presented with:
  • Psychomotor Retardation
  • Hyperthermia
  • Neuroleptic Malignant Syndrome
  • Serotonin Syndrome
  • Blood Pressure Fluctuation
  • Nuchal Rigidity
  • Hypertonia
  • Muscle Rigidity
  • Hyperhidrosis
which developed after the beginning of treatment. The patient was hospitalized and became disabled. This side effect report can indicate a possible existence of increased vulnerability to Mirtazapine treatment in female patients suffering from depression,bipolar disorder, resulting in Neuroleptic Malignant Syndrome.
Unresponsive To Stimuli, Neuroleptic Malignant Syndrome

A 72-year-old patient (weight: NA) from with the following symptoms: NA started Mirtazapine treatment (dosage: 30 Mg (30 Mg,2 In 1 D),oral) on Jan 02, 2012. Soon after starting Mirtazapine treatment, the consumer experienced several side effects, including:
  • Unresponsive To Stimuli
  • Neuroleptic Malignant Syndrome
. Concurrently used drugs:
  • Lactulose
  • Olanzapine (20 Mg (10 Mg,2 In 1 D),oral)
  • Cyanocobalamin
  • Mometasone Furoate
  • Albuterol Sulfate
  • Trazodone Hcl (200 Mg (200 Mg,1 In 1 D),oral)
  • Aspirin
  • Salmeterol And Fluticasone
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Mirtazapine side effects, such as Neuroleptic Malignant Syndrome.
Neuroleptic Malignant Syndrome, Rhabdomyolysis, Renal Failure, Lactic Acidosis, Hepatic Cirrhosis, Lacunar Infarction, Confusional State, Hyperventilation, Pyrexia

A female patient from DK was prescribed and started Mirtazapine on Mar 21, 2013. After Mirtazapine was administered, patient encountered several Mirtazapine side effects: neuroleptic malignant syndrome, rhabdomyolysis, renal failure, lactic acidosis, hepatic cirrhosis, lacunar infarction, confusional state, hyperventilation, pyrexia Additional patient health information: Female , 72 years of age, The consumer reported the following symptoms: was diagnosed with and. Mirtazapine dosage: 30 Mg, Qd. Concurrently used drugs:
  • Zeldox (40 Mg, Bid)
  • Zeldox (40 Mg, Bid)
  • Cipralex (30 Mg, Qd (daily Dose Of 1 Tablet In The Morning And 1.5 Tablet In The Evening))
  • Cipralex (30 Mg, Qd)
  • Litarex (1 Df (in The Morning))
  • Litarex (1.5 Df (in The Evening))
  • Litarex
  • Alprazolam (0.5 Mg, Qd)
The patient was hospitalized.
Lactic Acidosis, Renal Failure, Dyspnoea, Humerus Fracture, Osteosynthesis, Organ Failure, Rhabdomyolysis, Fall, Neuroleptic Malignant Syndrome

This report suggests a potential Mirtazapine Neuroleptic Malignant Syndrome side effect(s) that can have serious consequences. A 72-year-old female patient from DENMARK (weight:NA) was diagnosed with the following health condition(s): schizoaffective disorder and used Mirtazapine (dosage: 30 Mg;qd;po) starting NS. Soon after starting Mirtazapine the patient began experiencing various side effects, including:
  • Lactic Acidosis
  • Renal Failure
  • Dyspnoea
  • Humerus Fracture
  • Osteosynthesis
  • Organ Failure
  • Rhabdomyolysis
  • Fall
  • Neuroleptic Malignant Syndrome
Drugs used concurrently:NA. Although Mirtazapine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neuroleptic Malignant Syndrome, may still occur.
Renal Failure, Pyrexia, Osteosynthesis, Rhabdomyolysis, Neuroleptic Malignant Syndrome, Humerus Fracture, Dyspnoea, Organ Failure, Lactic Acidosis

An adverse event was reported by a physician on Oct 31, 2011 by a Female taking Mirtazapine (dosage: 30 Mg, Daily) was diagnosed with and. Location: DENMARK , 72 years of age, patient began experiencing various side effects, including: Patient felt the following Mirtazapine side effects: renal failure, pyrexia, osteosynthesis, rhabdomyolysis, neuroleptic malignant syndrome, humerus fracture, dyspnoea, organ failure, lactic acidosis. Additional medications/treatments:
Multiple prescriptions taken:
  • Alprazolam (Unk)
  • Lithium Citrate (Dose: 1+0+0+1.5, Strength: 6 Mmol Li+)
  • Furosemide (Unk)
  • Escitalopram (30 Mg, Daily)
  • Ferro Duretter (Unk)
  • Amlodipine (Unk)
  • Fragmin (Unk)
  • Ziprasidone Hydrochloride (40 Mg, 2x/day)
Neuroleptic Malignant Syndrome

This Neuroleptic Malignant Syndrome problem was reported by a health professional from UNITED KINGDOM. A 70-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Mirtazapine (dosage: Unk). The following drugs/medications were being taken at the same time: NA. When commencing Mirtazapine, the patient experienced the following unwanted symptoms /side effects:
  • Neuroleptic Malignant Syndrome
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Neuroleptic Malignant Syndrome, may become evident only after a product is in use by the general population.
Neuroleptic Malignant Syndrome

This is a Mirtazapine side effect report of a 70-year-old female patient (weight: NA) from UNITED KINGDOM. The patient developed the following symptoms/conditions: NA and was treated with Mirtazapine (dosage: NA) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Neuroleptic Malignant Syndrome
The patient was hospitalized. This opens a possibility that Mirtazapine could cause Neuroleptic Malignant Syndrome and that some female patients may be more susceptible.
Neuroleptic Malignant Syndrome

This Neuroleptic Malignant Syndrome side effect was reported by a pharmacist from UNITED KINGDOM on Sep 06, 2011. A female patient from UNITED KINGDOM , 70 years of age, was treated with Mirtazapine. Patient felt the following Mirtazapine side effects: neuroleptic malignant syndrome. Mirtazapine dosage: NA. The patient was hospitalized. These side effects may potentially be related to Mirtazapine.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Mirtazapine Neuroleptic Malignant Syndrome Causes and Reviews


Psychotic disorders are severe mental disorders that cause abnormal thinking and perceptions. People with psychoses lose touch with reality. Two of the main symptoms are delusions and hallucinations. Delusions are false beliefs, such as thinking that someone is plotting against you or that the TV is sending you secret messages. Hallucinations are false perceptions, such as hearing, seeing, or feeling something that is not there.

Schizophrenia is one type of psychotic disorder. People with bipolar disorder may also have psychotic symptoms. Other problems that can cause psychosis include alcohol and some drugs, brain tumors, brain infections, and stroke.

Treatment depends on the cause of the psychosis. It might involve drugs to control symptoms and talk therapy. Hospitalization is an option for serious cases where a person might be dangerous to himself or others.


Mirtazapine Neuroleptic Malignant Syndrome Reviews

Mon, 27 Sep 2010

Started on 15mg and now on 30 mg after two weeks. Feel absolutely awful. No energy, always tired and getting worse. Giving it a go as i'm told it will get better as body adjusts

Sat, 04 Sep 2010

I've been on this medication for 7 days (15mg). Right now it makes me verrrry sleepy about 40mins after I take it. I have excellent sleeps, but can sleep 12-14 hours if I don't set my alarm! The only other side effect I've experienced so far, is memory lapses. I'll go to the cupboard to get something, but then forget what I went to get (this happens at least twicea day).

Sat, 08 Jan 2011

Hi, I have been on mittazapine for 10 days, sleepy , tierd all the time and slugish in response to conversation just horrid feel gastly , head ace, The worst went to bed 11pm took the 15mg pill, went to the loo at 3am and collapsed on the bedroom floor damaging my back, I was told by the doctor my blood pressure had droped to low. NEVER AGAIN!!!!!!!!!!

Fri, 25 Feb 2011

I take Atenolol. Ramipril.Atorvastatin.Levothyroxine .Asprin.and Mirtazapine.Also a Glyceryl trinitrate spray as needed.I have dizziness,fatigue,muscle pain I itch at night , also i feel the cold more , sometimes have difficulty sleeping ,feeling anxious .Last night i dreamed i was a wake but a sleep at the same time but could not wake my self up . I have been to the Doc's drop the Mirtazapine down to 15mg . Also i have a frozzen shoulder . The Doc said it will take time ,at 59 how long is time well he did give me another sick note for 2 months .you have got to smile. on ESA for the last 8 months and still going

Mon, 23 Aug 2010

this med sucks and it will kill you... real talk

Tue, 21 Sep 2010

The above comment is too stupid, I actually LOLed at you Pete... lol you gave it 2 days and your complaining about the side-effects? and on 15 mgs? LMAO!!! It takes couple weeks at least to cope with the side-effects; just like many other drug. What is this; your first ever prescription medication? Your comment is misleading for others and very stupid.

I was on 45 mgs Mirtazipine for 2 years and even when I stopped abruptly I experienced zero to none of the withdrawal symptoms people are talking about... (but that might just be me, everyone is diff, however I never heard anyone dying from taking this medication. Unless combined with Benzos, pain killers and alcohol at the same time as it will def in that case cause severe CNS Depression and consequently death.

I would take 30 mg at nighttime for anxiety/insomnia and 15mgs in the mornings or after lunch. It is an excellent antidepressant, however you munch out a lot while on it, and you def put of more weight than before you start the medication. So, if weight gain is an issue for you, stay away from this one. Talk to your physician about alternate choices. Probably the best is Welbutrin if you weight is an issue for you.

Thu, 24 Mar 2011

the effects on my system where wide andvariedfirst thing i noticed where vividdreamsmore to the pointnight terrorstheymanifestedin aterror-strickensensation.Icould herewhatwas going on around me but waspowerlessto move I live alone and I amnearly50years old but I could hear myselfshoutingfor help but there was no one.Ifelt that if i did not move and soonI woulddie, then I started putting lots of weight on and haveclimbedupto 18 stone, then mouth ulcers and gum disorders then to cap it off I GOT WIDESPREADParesthesia,I only needed themoriginalyto help me sleep as my darling wife of 32 years told me i wassurplus torequirements, and that after 15 years as a coal miner,BUT YOU KNOW. I STILL LOVE HER VERY MUCHwewhere school sweethearts pathetic I know. as for thE mirtaz I have of course stopped taking them.I laterfoundouttheyarealsoprescribedfor p.t.s.s,and now i'm toembarrassedto leave my flat.anywaylet this be a warning to others. thanks for taking the time to read this and get them banned TTFN

Tue, 24 Jan 2012

Hi, I just started Mirtazapine in 11/11 because of the sensitivity of my body and how it reacts to medications I had to start at a low dosage (15mg cut into 4 pc. for 3.75mg) I have recently increased my dosage to 7.5mg (1/2 15mg tablet) I have experienced weight gain (20lbs in one month) breast enlargement, blurred vision, angered easily and we just did a blood panel and I am showing elevated liver enzymes more than 3 times the high amount, we have done a ultra sound and my liver looks great I also have no accompanying symptems (i.e. jaundice, dark urine)! However I am also getting low HCT (hematocrit) and feel very tired at times. Low hematocrit is a sign of anemia however I clot just fine and am not an excessive bleeder. I also have noticed swelling in my extremities exspecially my hands. I follow up with the Dr on 2/7/12 to do another CBC.

Wed, 13 Oct 2010

Wery tired and sleepy during the day, but suffering from insomnia at night.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Mirtazapine Side Effects

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Confusional State (206)
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Depression (160)
Overdose (148)
Anxiety (147)
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Dizziness (130)
Agitation (130)
Condition Aggravated (123)
Somnolence (117)
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Weight Increased (90)
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Myalgia (73)
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Cardiac Arrest (71)
Inappropriate Antidiuretic Hormone Secretion (71)
Feeling Abnormal (70)
Toxicity To Various Agents (69)
Asthenia (69)
Diarrhoea (67)
Syncope (62)
Hyperhidrosis (61)
Neuroleptic Malignant Syndrome (61)
Pain In Extremity (61)
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Hypotension (56)
Irritability (56)
Pain (55)
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