CLONIDINE Injection, Solution [X-GEN Pharmaceuticals, Inc.]

Updated Date: Feb 20, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

A Review of the Use of Clonidine as a Sleep Aid in the Child and Adolescent Population

(Source: Clinical Pediatrics)

In Vitro Stability of Low�Concentration Ziconotide Alone or in Admixtures in Intrathecal Pumps

ConclusionsAt the low ziconotide concentrations studied, the degradation of ziconotide admixed with other drugs was linear and only weakly influenced by the baseline concentration. Linear regression with intrapolation to 30 days showed that the degradation of ziconotide admixed with other drugs was consistent with previously published data. (Source: Neuromodulation)

Intranasal clonidine pharmacokinetics.

Authors: Blackburn L, Almenrader N, Larsson P, Anderson BJ PMID: 24467572 [PubMed - in process] (Source: Paediatric Anaesthesia)

Clonidine premedication for postoperative analgesia in children.

CONCLUSIONS: There were only 11 relevant trials studying 742 children having surgery where premedication with clonidine was compared to placebo or other drug treatment. Despite heterogeneity between trials, clonidine premedication in an adequate dosage (4 ”g/kg) was likely to have a beneficial effect on postoperative pain in children. Side effects were minimal, but some of the studies used atropine prophylactically with the intention of preventing bradycardia and hypotension. Further research is required to determine under what conditions clonidine premedication is most effective in providing postoperative pain relief in children. PMID: 24470114 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>

Pre-Surgical Drug May Ease Recovery and Reduce Pain for Kids

01/30/2014, The Cochrane Library - A new evidence review from The Cochrane Library found that administering a drug called clonidine before surgery may be a good alternative for controlling post-surgical pain and help reduce a child's anxiety after surgery. (Source: Health Behavior News Service)

Pre-surgical drug may ease recovery, reduce pain for kids

A new evidence review found that administering a drug called clonidine before surgery may be a good alternative for controlling post-surgical pain and help reduce a childâ??s anxiety after surgery. (Source: ScienceDaily Headlines)

CLONIDINE HYDROCHLORIDE Tablet [McKesson Packaging Services A Business Unit Of McKesson Corporation]

Updated Date: Jan 29, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Intranasal clonidine pharmacokinetics

(Source: Pediatric Anesthesia)

KAPVAY (Clonidine Hydrochloride) Tablet, Extended Release [Concordia Pharmaceuticals Inc.]

Updated Date: Jan 28, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>

Effects of clonidine in the isolated rat testicular capsule.

Authors: Dantas da Silva JĂșnior E, Palmieri de Souza B, Quintella Dantas Rodrigues J, Caricati-Neto A, Jurkiewicz A, Jurkiewicz NH Abstract The testicular capsule contracts in response to noradrenaline and adrenaline, but the effects of adrenoceptor agonists, as for instance clonidine, had not yet been thoroughly evaluated. The testicular capsule from adult male Wistar rats was isolated and mounted in organ bath and cumulative concentration curves were performed for clonidine and other adrenergic agonists in the absence or presence of α-adrenoceptors antagonists. The order of potency for agonists (pD2) was clonidine=adrenaline&gt;UK 14,304&gt;noradrenaline&gt;phenylephrine&gt;methoxamine. The consecutive curves for clonidine showed desensitization with 3-fold rightward shift and ...

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