BUPROPION Tablet, Extended Release [Zydus Pharmaceuticals (USA) Inc.]

Updated Date: Feb 18, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Asystole shortly after intravenous fat emulsion for overdose: causation or coincidence?

3 out of 5 stars Asystole Immediately Following Intravenous Fat Emulsion for Overdose. Cole JB et al. J Med Toxicol 2014 Feb 12. [Epub ahead of print] Abstract This case paper describes 2 patients who developed asystolic within 60 seconds of being given intravenous fat emulsion (IFE) bolus for treatment of severe cardiotoxicity. Both patients had return of spontaneous circulation (ROSC) after several minutes of cardiopulmonary resuscitation. Unfortunately, both patients died days after admission from multisystem organ failure. Patient A,  a 50-year-old woman, had ingested an undetermined about of metoprolol and bupropion in a suicide attempt. She seized and then developed bradycardia and hypotension unresponsive to multiple interventions (fluid, glucagon, insulin). Within 30 sec of recei...

Female Clitoral Priapism: An Over?the?Counter Option for Management

ConclusionsOral pseudoephedrine may be a reasonable option for certain patients, and may be considered as a first?line therapy and adjunct to conservative measures. Unger CA and Walters MD. Female clitorial priapism: An over?the?counter option for management. J Sex Med **;**:**??**. (Source: The Journal of Sexual Medicine)

Effects of bupropion and pramipexole on cell proliferation in the hippocampus of adrenocorticotropic hormone-treated rats.

In this study, we used the mitotic marker 5-bromo-2'-deoxyridine to investigate the effects of bupropion and pramipexole on cell proliferation in the subgranular zone of the hippocampal dentate gyrus following chronic treatment with ACTH. The ACTH treatment for 14??d decreased adult hippocampal cell proliferation. The chronic administration of bupropion for 14??d blocked the loss of cell proliferation resulting from the chronic treatment with ACTH, whereas pramipexole did not. The administration of bupropion may have treatment-resistant antidepressive properties, which may be partly attributed to the normalization of hippocampal cell proliferation. PMID: 24492730 [PubMed - in process] (Source: Biological and Pharmaceutical Bulletin)

Asystole Immediately Following Intravenous Fat Emulsion for Overdose.

This report adds only case experience, not clarity. We report two cardiac arrests that were temporally associated with IFE. PMID: 24519703 [PubMed - as supplied by publisher] (Source: Journal of Medical Toxicology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>

Nicotinic receptor antagonists as treatments for nicotine abuse.

Authors: Crooks PA, Bardo MT, Dwoskin LP Abstract Despite the proven efficacy of current pharmacotherapies for tobacco dependence, relapse rates continue to be high, indicating that novel medications are needed. Currently, several smoking cessation agents are available, including varenicline (Chantix®), bupropion (Zyban®), and cytisine (Tabex®). Varenicline and cytisine are partial agonists at the α4β2* nicotinic acetylcholine receptor (nAChR). Bupropion is an antidepressant but is also an antagonist at α3β2* ganglionic nAChRs. The rewarding effects of nicotine are mediated, in part, by nicotine-evoked dopamine (DA) release leading to sensitization, which is associated with repeated nicotine administration and nicotine addiction. Receptor antagonists that selectivity target ...

Bupropion and bupropion analogs as treatments for CNS disorders.

Authors: Carroll FI, Blough BE, Mascarella SW, Navarro HA, Lukas RJ, Damaj MI Abstract Bupropion, introduced as an antidepressant in the 1980s, is also effective as a smoking cessation aid and is beneficial in the treatment of methamphetamine addiction, cocaine dependence, addictive behaviors such as pathological gambling, and attention deficit hyperactivity disorder. (2S,3S)-hydroxybupropion is an active metabolite of bupropion produced in humans that contributes to antidepressant and smoking cessation efficacy and perhaps benefits in other CNS disorders. Mechanisms underlying its antidepressant and smoking abstinence remain elusive. However, it seems likely that efficacy is due to a combination of the effects of bupropion and/or its active metabolite (2S,3S)-hydroxybupropion invo...

Smoking Cessation

Cigarette smoking is a major preventable cause of morbidity and mortality. It is the major risk factor for chronic obstructive pulmonary disease in the developed world. Smoking is a chronic relapsing disease. Optimal treatment includes nonpharmacologic support, together with pharmacotherapy. All clinicians should be comfortable with the use of nicotine replacement therapy, bupropion, and varenicline. Second-line therapies can be used by those familiar with their use. Effective use of these medications requires their integration into an effective management plan, which is likely to be a long-term undertaking, involving several cycles of remission and relapse. (Source: Clinics in Chest Medicine)

BUPROPION HYDROCHLORIDE Tablet, Film Coated [BluePoint Laboratories]

Updated Date: Feb 7, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

BUPROPION HYDROCHLORIDE Tablet, Film Coated, Extended Release [Jubilant Cadista Pharmaceuticals Inc.]

Updated Date: Feb 3, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>

BUPROPION HYDROCHLORIDE Tablet, Film Coated, Extended Release [REMEDYREPACK INC. ]

Updated Date: Jan 31, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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