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Pristiq Irritability Side Effects

Pristiq Irritability Side Effect Reports


The following Pristiq Irritability side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Irritability, can occur, and what you can do about them.

A side effect could appear soon after you start Pristiq or it might take time to develop.



Irritability, Nausea, Dizziness, Paraesthesia, Abnormal Behaviour, Amnesia

This Irritability side effect was reported by a consumer or non-health professional from US. A 44-year-old patient (weight:NA) experienced the following symptoms/conditions: depression. The patient was prescribed Pristiq (dosage: NA), which was started on Mar 07, 2011. Concurrently used drugs: NA. When starting to take Pristiq the consumer reported the following symptoms:
  • Irritability
  • Nausea
  • Dizziness
  • Paraesthesia
  • Abnormal Behaviour
  • Amnesia
These side effects may potentially be related to Pristiq.
Off Label Use, Weight Decreased, Decreased Appetite, Hot Flush, Hyperhidrosis, Temperature Intolerance, Irritability, Headache

This Irritability Pristiq side effect was reported by a consumer or non-health professional from BR on Mar 25, 2013. A Female , 40 years of age, was diagnosed with and was treated with Pristiq. The patient presented the following health conditions:
  • Off Label Use
  • Weight Decreased
  • Decreased Appetite
  • Hot Flush
  • Hyperhidrosis
  • Temperature Intolerance
  • Irritability
  • Headache
. Pristiq dosage: 50 Mg, 1x/day. Additional drugs used at the same time: NA.
Withdrawal Syndrome, Irritability, Agitation, Dizziness, Anxiety, Headache, Insomnia, Feeling Abnormal

This is a Pristiq side effect report of a 51-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: depression,hypertension, who was treated with Pristiq (dosage:50 Mg, 1x/day, start time: NS), combined with:
  • Metoprolol (25 Mg, 1x/day)
, and developed a serious reaction and a Irritability side effect. The patient presented with:
  • Withdrawal Syndrome
  • Irritability
  • Agitation
  • Dizziness
  • Anxiety
  • Headache
  • Insomnia
  • Feeling Abnormal
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Pristiq treatment in female patients suffering from depression,hypertension, resulting in Irritability.

Agitation, Tachyphrenia, Irritability, Fear, Restlessness, Anxiety

A 24-year-old female patient (weight: NA) from US with the following symptoms: NA started Pristiq treatment (dosage: 50 Mg, Once (single)) on Feb 19, 2013. Soon after starting Pristiq treatment, the consumer experienced several side effects, including:
  • Agitation
  • Tachyphrenia
  • Irritability
  • Fear
  • Restlessness
  • Anxiety
. Concurrently used drugs:
  • Clozapine (Unk)
This finding indicates that some patients can be more vulnerable to developing Pristiq side effects, such as Irritability.
Erectile Dysfunction, Agitation, Feeling Abnormal, Anxiety, Irritability

A patient from US was prescribed and started Pristiq on Feb 21, 2013. Patient felt the following Pristiq side effects: erectile dysfunction, agitation, feeling abnormal, anxiety, irritability Additional patient health information: male , 56 years of age, weighting 180.0 lb, The consumer reported the following symptoms: was diagnosed with and. Pristiq dosage: 100 Mg, Daily. Concurrently used drugs: NA.
Affect Lability, Paraesthesia, Dizziness, Irritability, Hostility, Nausea, Suicidal Ideation, Withdrawal Syndrome

This report suggests a potential Pristiq Irritability side effect(s) that can have serious consequences. A 50-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): menopausal symptoms,irritability,hot flush and used Pristiq (dosage: NA) starting May 25, 2010. Soon after starting Pristiq the patient began experiencing various side effects, including:
  • Affect Lability
  • Paraesthesia
  • Dizziness
  • Irritability
  • Hostility
  • Nausea
  • Suicidal Ideation
  • Withdrawal Syndrome
Drugs used concurrently:NA. Although Pristiq demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Irritability, may still occur.
Appendix Disorder, Neoplasm, Thrombosis, Depressed Mood, Irritability, Feeling Abnormal

An adverse event was reported by a consumer or non-health professional on Feb 06, 2013 by a Female taking Pristiq (dosage: 100mg Daily) was diagnosed with and. Location: US , 48 years of age, weighting 153.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Pristiq side effects: appendix disorder, neoplasm, thrombosis, depressed mood, irritability, feeling abnormal. Additional medications/treatments:
Off Label Use, Irritability, Agitation, Urine Output Decreased, Paraesthesia, Hypoaesthesia, Headache

This Irritability problem was reported by a consumer or non-health professional from US. A 45-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): anxiety,depression,sleep problem.On Dec 15, 2012 a consumer started treatment with Pristiq (dosage: 50 Mg, 1x/day). The following drugs/medications were being taken at the same time: NA. When commencing Pristiq, the patient experienced the following unwanted symptoms /side effects:
  • Off Label Use
  • Irritability
  • Agitation
  • Urine Output Decreased
  • Paraesthesia
  • Hypoaesthesia
  • Headache
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Irritability, may become evident only after a product is in use by the general population.
Overweight, Anxiety, Irritability, Personality Change

This is a Pristiq side effect report of a 55-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: depression,feeling bad and was treated with Pristiq (dosage: 50 Mg, Unk) starting 2012. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Overweight
  • Anxiety
  • Irritability
  • Personality Change
This opens a possibility that Pristiq could cause Irritability and that some female patients may be more susceptible.
Withdrawal Syndrome, Photophobia, Hyperacusis, Headache, Dizziness, Paraesthesia Oral, Irritability, Nausea, Diarrhoea

This Irritability side effect was reported by a consumer or non-health professional from US on Nov 05, 2012. A female patient from US , 41 years of age, weighting 125.0 lb, was diagnosed with and was treated with Pristiq. Directly after treatment started, patient experienced the unwanted or unexpected Pristiq side effects: withdrawal syndrome, photophobia, hyperacusis, headache, dizziness, paraesthesia oral, irritability, nausea, diarrhoea. Pristiq dosage: 50 Mg, 1x/day. These side effects may potentially be related to Pristiq.
Mood Altered, Irritability, Hostility, Anger, Dizziness

This Irritability side effect was reported by a consumer or non-health professional from US. A 44-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression. The patient was prescribed Pristiq (dosage: 50 Mg, Daily), which was started on 2012. Concurrently used drugs: NA. When starting to take Pristiq the consumer reported the following symptoms:
  • Mood Altered
  • Irritability
  • Hostility
  • Anger
  • Dizziness
These side effects may potentially be related to Pristiq.
Off Label Use, Paraesthesia, Dizziness, Irritability, Lethargy, Feeling Abnormal, Anxiety

This Irritability Pristiq side effect was reported by a consumer or non-health professional from US on Nov 19, 2012. A male , 29 years of age, weighting 195.0 lb, was diagnosed with and was treated with Pristiq. The patient presented the following health conditions:
  • Off Label Use
  • Paraesthesia
  • Dizziness
  • Irritability
  • Lethargy
  • Feeling Abnormal
  • Anxiety
. Pristiq dosage: 50 Mg Every Other Day. Additional drugs used at the same time: NA.
Tinnitus, Mania, Impulsive Behaviour, Abulia, Irritability, Aggression, Hyperacusis, Tachyphrenia

This is a Pristiq side effect report of a 42-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: anxiety, who was treated with Pristiq (dosage:100 Mg Daily Po, start time: Sep 12, 2012), combined with: NA., and developed a serious reaction and a Irritability side effect. The patient presented with:
  • Tinnitus
  • Mania
  • Impulsive Behaviour
  • Abulia
  • Irritability
  • Aggression
  • Hyperacusis
  • Tachyphrenia
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Pristiq treatment in patients suffering from anxiety, resulting in Irritability.
Personality Change, Irritability

A 55-year-old patient (weight: NA) from US with the following symptoms: depression started Pristiq treatment (dosage: 50 Mg, 1x/day) on NS. Soon after starting Pristiq treatment, the consumer experienced several side effects, including:
  • Personality Change
  • Irritability
. Concurrently used drugs:
  • Wellbutrin (Unk)
  • Atenolol (Unk)
  • Lasix (Unk)
  • Xanax (1 Mg, 2x/day)
  • Zolpidem (Unk)
This finding indicates that some patients can be more vulnerable to developing Pristiq side effects, such as Irritability.
Suicidal Ideation, Depression, Cognitive Disorder, Amnesia, Withdrawal Syndrome, Activities Of Daily Living Impaired, Nervous System Disorder, Irritability

A female patient from US was prescribed and started Pristiq on Sep 19, 2012. After Pristiq was administered, patient encountered several Pristiq side effects: suicidal ideation, depression, cognitive disorder, amnesia, withdrawal syndrome, activities of daily living impaired, nervous system disorder, irritability Additional patient health information: Female , 33 years of age, weighting 130.0 lb, The consumer reported the following symptoms: . Pristiq dosage: 50 Mg, Daily. Concurrently used drugs: NA.
Vitamin D Decreased, Vitamin B12 Decreased, Hyperhidrosis, Depressed Mood, Dizziness, Irritability, Nausea

This report suggests a potential Pristiq Irritability side effect(s) that can have serious consequences. A 37-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): depression,affective disorder,attention deficit/hyperactivity disorder,feeling of relaxation and used Pristiq (dosage: 50 Mg, 1x/day) starting 201201. Soon after starting Pristiq the patient began experiencing various side effects, including:
  • Vitamin D Decreased
  • Vitamin B12 Decreased
  • Hyperhidrosis
  • Depressed Mood
  • Dizziness
  • Irritability
  • Nausea
Drugs used concurrently:
  • Lamotrigine (100 Mg, Unk)
  • Strattera (80 Mg, Unk)
  • Clonazepam (1 Mg, Unk)
Although Pristiq demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Irritability, may still occur.
Withdrawal Syndrome, Influenza Like Illness, Pain Of Skin, Convulsion, Paraesthesia, Suicidal Ideation, Irritability

An adverse event was reported by a consumer or non-health professional on Jun 18, 2012 by a Female taking Pristiq (dosage: 50 Mg, 1x/day) was diagnosed with and. Location: UNITED STATES , weighting 135.0 lb, patient began experiencing various side effects, including: Patient felt the following Pristiq side effects: withdrawal syndrome, influenza like illness, pain of skin, convulsion, paraesthesia, suicidal ideation, irritability. Additional medications/treatments:
Irritability, Dissociation, Convulsion, Insomnia, Diarrhoea, Paraesthesia, Depression, Anxiety

This Irritability problem was reported by a consumer or non-health professional from UNITED STATES. A female patient (weight: NA) was diagnosed with the following medical condition(s): depression.On Jan 01, 2010 a consumer started treatment with Pristiq (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Pristiq, the patient experienced the following unwanted symptoms /side effects:
  • Irritability
  • Dissociation
  • Convulsion
  • Insomnia
  • Diarrhoea
  • Paraesthesia
  • Depression
  • Anxiety
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Irritability, may become evident only after a product is in use by the general population.
Tremor, Vision Blurred, Gait Disturbance, Irritability, Neck Pain, Dizziness, Diplopia, Mood Swings

This is a Pristiq side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: depression,stress and was treated with Pristiq (dosage: 100 Mg, 1x/day) starting Mar 01, 2012. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Tremor
  • Vision Blurred
  • Gait Disturbance
  • Irritability
  • Neck Pain
  • Dizziness
  • Diplopia
  • Mood Swings
This opens a possibility that Pristiq could cause Irritability and that some female patients may be more susceptible.
Renal Impairment, Depression, Osteoporosis, Blood Creatinine Increased, Emotional Disorder, Irritability

This Irritability side effect was reported by a consumer or non-health professional from UNITED STATES on Mar 21, 2012. A female patient from UNITED STATES , weighting 103.0 lb, was diagnosed with and was treated with Pristiq. Patient felt the following Pristiq side effects: renal impairment, depression, osteoporosis, blood creatinine increased, emotional disorder, irritability. Pristiq dosage: 100 Mg, 1x/day.
Multiple prescriptions taken:
  • Klonopin (Unk, As Needed)
  • Effexor Xr
  • Levothyroxine (Unk)
  • Trazodone (Unk)
These side effects may potentially be related to Pristiq.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Pristiq Irritability Causes and Reviews


For most adults, moderate alcohol use is probably not harmful. However, about 18 million adult Americans have an alcohol use disorder (AUD). This means that their drinking causes distress and harm. It includes alcoholism and alcohol abuse.

Alcoholism, or alcohol dependence, is a disease that causes

  • Craving - a strong need to drink
  • Loss of control - not being able to stop drinking once you've started
  • Physical dependence - withdrawal symptoms
  • Tolerance - the need to drink more alcohol to feel the same effect

With alcohol abuse, you are not physically dependent, but you still have a serious problem. The drinking may cause problems at home, work, or school. It may cause you to put yourself in dangerous situations, or lead to legal or social problems.

Another common problem is binge drinking. It is drinking about five or more drinks in two hours for men. For women, it is about four or more drinks in two hours.

Too much alcohol is dangerous. Heavy drinking can increase the risk of certain cancers. It can cause damage to the liver, brain, and other organs. Drinking during pregnancy can harm your baby. Alcohol also increases the risk of death from car crashes, injuries, homicide, and suicide.

You may have an AUD if you can answer yes to two or more of these questions:

In the past year, have you

  • Ended up drinking more or for a longer time than you had planned to?
  • Wanted to cut down or stop drinking, or tried to, but couldn't?
  • Spent a lot of your time drinking, or recovering from drinking?
  • Felt a strong need to drink?
  • Found that drinking - or being sick from drinking - often interfered with your family life, job, or school?
  • Kept drinking even though it was causing trouble with your family or friends?
  • Given up or cut back on activities that you enjoyed just so you could drink?
  • Gotten into dangerous situations while drinking or after drinking? Some examples are driving drunk and having unsafe sex.
  • Kept drinking even though it was making you feel depressed or anxious? Or when it was adding to another health problem?
  • Had to drink more and more to feel the effects of the alcohol?
  • Had withdrawal symptoms when the alcohol was wearing off? They include trouble sleeping, shakiness, Irritability, anxiety, depression, restlessness, nausea, and sweating. In severe cases, you could have a fever, seizures, or hallucinations.

If you have any of these symptoms, your drinking may already be a cause for concern. The more symptoms you have, the more serious the problem is. If you think you might have an AUD, see your health care provider for an evaluation. Your provider can help make a treatment plan, prescribe medicines, and if needed, give you treatment referrals.

NIH: National Institute on Alcohol Abuse and Alcoholism


Pristiq Irritability Reviews

Fri, 02 Mar 2012

oh and i take levothroxin and lisinopril

Mon, 07 May 2012

Are you bipolar. Could it be one of the other meds or a reaction to all of them combined.

Mon, 23 Jan 2012

I am on week 10 of taking Pristiq 50mg, 1 daily ~ all of the symptoms (irritation, negative, sad, agiation, insecurity, etc.) that went away the first two weeks are back with a vengance ~ what is going on???  Does this affect hormones?  No one can answer my questions.

Fri, 18 May 2012

Nice post and i learned many things. I appreciate this information. Many drugs have side effects so we should use drugs with the consult of doctor. Great post. Keep it up.

Sun, 11 Mar 2012

are there any concerns with starting Pristiq about 1 month befor cataract surgery??

Tue, 26 Jul 2011

I was prescribed Pristiq for chronic depression, as I take tramadol for R/Arthritis I stopped taking tramodol, as my pains got worse I started taking tramadol l a day amazing enough I found taking both seem to improve the depression considerably so will be discussing this with my GP

Sun, 06 Nov 2011
WHEN I EAT AND SWALLOWAD WHEN THE FOOD GEY TO THE TOP OF MY STOMACH I HAVE SHARP PAIN .CAN ONLY DRINK WATER ANDTHE LIKES.
Tue, 29 Jun 2010
I took wellbutrin two yrs ago and developed symptome of GERD, inability to swallow comfortably, abdominal pain. Took thousands of dollars of tests and was told it was not the medication, it was merely a coincidence. Fast forward to last month when I began taking a similar med - Pristiq. It took three weeks but the swallowing problem, throat clearing and stomach pain have all returned. Saw my psychiatrist and moved back to Effexor. It's sad we did not know about this before all that I had to deal with.
Fri, 19 Nov 2010
I am a 42 year old female who was started on 50 mg. once a day Pristiq for depression. It has been 4 days and I have lower abdominal pain everyday all day and night. I have been taking Tylenol for the pain around the clock. I also can't sleep much. I wake up everyday at 2am. I will see if these symptoms go away but I don't know if I can tolerate the pain. I sweat alot too, but that I can deal with
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Pristiq Side Effects

Nausea (771)
Dizziness (678)
Headache (651)
Insomnia (567)
Anxiety (497)
Fatigue (454)
Feeling Abnormal (449)
Condition Aggravated (399)
Hyperhidrosis (296)
Depression (277)
Diarrhoea (261)
Malaise (227)
Crying (226)
Somnolence (214)
Tremor (199)
Decreased Appetite (193)
Irritability (181)
Suicidal Ideation (180)
Paraesthesia (178)
Blood Pressure Increased (171)
Constipation (158)
Weight Increased (158)
Vomiting (156)
Agitation (154)
Asthenia (148)
Dry Mouth (146)
Hypertension (143)
Palpitations (133)
Vision Blurred (127)
Anger (126)
Pain (120)
Off Label Use (116)
Dyspnoea (111)
Nervousness (108)
Weight Decreased (107)
Heart Rate Increased (106)
Unevaluable Event (105)
Disturbance In Attention (103)
Abnormal Dreams (101)
Tinnitus (93)
Confusional State (89)
Withdrawal Syndrome (89)
Emotional Disorder (83)
Aggression (81)
Pruritus (79)
Alopecia (77)
Activities Of Daily Living Impaired (77)
Abdominal Pain Upper (77)
Convulsion (76)
Restlessness (75)

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Pristiq Common Side Effects

If you experienced any harmful or unwanted effects of Mucinex, please share your experience. This could help to raise awareness about Mucinex side effects, identify uknown risks and inform health professionals and patients taking Mucinex.

Examples: headache, dizziness

The most commonly reported Pristiq side effects (click to view or check a box to report):

Nausea (759)
Dizziness (666)
Headache (640)
Insomnia (550)
Anxiety (482)
Fatigue (441)
Feeling Abnormal (438)
Condition Aggravated (394)
Hyperhidrosis (296)
Depression (272)
Diarrhoea (261)
Malaise (227)
Crying (226)
Somnolence (214)
Tremor (196)
Decreased Appetite (191)
Paraesthesia (178)
Irritability (178)
Suicidal Ideation (175)
Blood Pressure Increased (168)

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