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Promethazine Fatigue Side Effects

Promethazine Fatigue Side Effect Reports


The following Promethazine Fatigue side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Fatigue, can occur, and what you can do about them.

A side effect could appear soon after you start Promethazine or it might take time to develop.



Enteritis, Fatigue, Intestinal Ulcer

This Fatigue side effect was reported by a consumer or non-health professional from BRAZIL. A female patient (weight:NA) experienced the following symptoms/conditions: bipolar disorder. The patient was prescribed Promethazine (dosage: NA), which was started on Jan 01, 2010. Concurrently used drugs:
  • Remicade
  • Remicade
  • Haloperidol
  • Remicade
  • Chlorpromazine
  • Remicade
  • Remicade
  • Remicade
When starting to take Promethazine the consumer reported the following symptoms:
  • Enteritis
  • Fatigue
  • Intestinal Ulcer
These side effects may potentially be related to Promethazine.
Diverticulum, Nodule, Haemorrhage, Fatigue, Lower Gastrointestinal Haemorrhage, Anorectal Disorder, Vomiting, Diarrhoea, Anaemia

This Fatigue Promethazine side effect was reported by a physician from UNITED STATES on Apr 28, 2011. A Female , 75 years of age, weighting 191.0 lb, was treated with Promethazine. The patient presented the following health conditions:
  • Diverticulum
  • Nodule
  • Haemorrhage
  • Fatigue
  • Lower Gastrointestinal Haemorrhage
  • Anorectal Disorder
  • Vomiting
  • Diarrhoea
  • Anaemia
. Promethazine dosage: NA. Additional drugs used at the same time:
  • Metoclopramide
  • Imodium
  • Acidophilus
  • Revlimid (5 Mg, 1 In 1 D, Po 25 Mg, 1 In 1 D, Po)
  • Revlimid (5 Mg, 1 In 1 D, Po 25 Mg, 1 In 1 D, Po)
  • Revlimid (5 Mg, 1 In 1 D, Po 25 Mg, 1 In 1 D, Po)
  • Aspirin
  • Dexamethasone
The patient was hospitalized.
Liver Injury, Fatigue, Hepatic Enzyme Increased, Jaundice, Pyrexia, Nausea, Mental Status Changes, Agitation

This is a Promethazine side effect report of a 30-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Promethazine (dosage:NA, start time: Sep 01, 2001), combined with: NA., and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Liver Injury
  • Fatigue
  • Hepatic Enzyme Increased
  • Jaundice
  • Pyrexia
  • Nausea
  • Mental Status Changes
  • Agitation
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Promethazine treatment in female patients suffering from NA, resulting in Fatigue.

Weight Decreased, Nausea, Fatigue, Depression, Decreased Appetite, Diarrhoea, Crying

A 55-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Promethazine(promethazine)(promethazine) treatment (dosage: NA) on Jun 07, 2011. Soon after starting Promethazine(promethazine)(promethazine) treatment, the consumer experienced several side effects, including:
  • Weight Decreased
  • Nausea
  • Fatigue
  • Depression
  • Decreased Appetite
  • Diarrhoea
  • Crying
. Concurrently used drugs:
  • Prilosec(omeprazole)(omeprazole)
  • Trazodone(trazodone)(trazodone)
  • Lorazepam
  • Pristiq(antidepressants)(desvenlafaxine)
  • Ondansetron
  • Benlysta (10 Mg/kg, Every 2 Weeks X3 Then Every 4 Weeks, Intravenous)
  • Fentanyl
  • Furosemide
This finding indicates that some patients can be more vulnerable to developing Promethazine(promethazine)(promethazine) side effects, such as Fatigue.
Pleural Effusion, Osteomyelitis, Musculoskeletal Pain, Hypokalaemia, Arthralgia, Fatigue, Deafness, Swelling Face, Anaemia

A patient from UNITED STATES was prescribed and started Promethazine on Jan 20, 2012. Patient felt the following Promethazine side effects: pleural effusion, osteomyelitis, musculoskeletal pain, hypokalaemia, arthralgia, fatigue, deafness, swelling face, anaemia Additional patient health information: male , weighting 205.0 lb, The consumer reported the following symptoms: . Promethazine dosage: NA. Concurrently used drugs:
  • Protonix
  • Lisinopril (5 Mg, Qd)
  • Coreg
  • Potassium Chloride
  • Dulcolax
  • Neurontin
  • Augmentin '125'
  • Cyproheptadine Hcl
The patient was hospitalized and became disabled.
Dyskinesia, Brain Mass, Amnesia, Fatigue, Convulsion, Cerebral Haemangioma, Muscle Tightness, Muscle Spasms

This report suggests a potential Promethazine Fatigue side effect(s) that can have serious consequences. A female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): nausea,migraine and used Promethazine (dosage: 25 Mg, 3x/day) starting Jan 03, 2012. Soon after starting Promethazine the patient began experiencing various side effects, including:
  • Dyskinesia
  • Brain Mass
  • Amnesia
  • Fatigue
  • Convulsion
  • Cerebral Haemangioma
  • Muscle Tightness
  • Muscle Spasms
Drugs used concurrently:
  • Baclofen (10 Mg, 3x/day)
  • Percocet (Unk)
  • Baclofen
  • Chantix (0.5 Mg, Daily)
  • Cymbalta (60 Mg, Daily)
Although Promethazine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Nausea, Fatigue, Abdominal Pain, Vomiting, Cholelithiasis, Cholecystectomy, Cholecystitis Chronic

An adverse event was reported by a pharmacist on Jan 31, 2011 by a Female taking Promethazine (dosage: 25 Mg, Unk) . Location: UNITED STATES , 18 years of age, weighting 128.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Promethazine side effects: nausea, fatigue, abdominal pain, vomiting, cholelithiasis, cholecystectomy, cholecystitis chronic. Additional medications/treatments:
Associated medications used:
  • Metoclopramide (500 Mg, Unk)
  • Yaz (1 Tab / Day)
  • Prednisone Tab (20 Mg, Unk)
  • Metoclopramide (10 Mg, Unk)
  • Zantac (150 Mg, Qd)
  • Metronidazole (500 Mg, Unk)
  • Yaz
  • Patanol (0.1 %, Unk)
Fatigue, Paraesthesia, Confusional State, Neuroleptic Malignant Syndrome, Hypoventilation, Anxiety

This Fatigue problem was reported by a consumer or non-health professional from UNITED STATES. A patient (weight: NA) was diagnosed with the following medical condition(s): nasopharyngitis,cough.On Feb 03, 2011 a consumer started treatment with Promethazine Hcl And Codeine Phosphate (dosage: 1 Teaspoon Every 4-6 Hrs Po). The following drugs/medications were being taken at the same time: NA. When commencing Promethazine Hcl And Codeine Phosphate, the patient experienced the following unwanted symptoms /side effects:
  • Fatigue
  • Paraesthesia
  • Confusional State
  • Neuroleptic Malignant Syndrome
  • Hypoventilation
  • Anxiety
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Cholecystitis Chronic, Vomiting, Nausea, Abdominal Pain, Cholelithiasis, Dizziness, Fatigue

This is a Promethazine side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Promethazine (dosage: NA) starting Sep 04, 2008. Concurrently used drugs:
  • Drospirenone And Ethinyl Estradiol
  • Metformin
  • Meclizine
Soon after that, the consumer experienced the following of symptoms:
  • Cholecystitis Chronic
  • Vomiting
  • Nausea
  • Abdominal Pain
  • Cholelithiasis
  • Dizziness
  • Fatigue
The patient was hospitalized. This opens a possibility that Promethazine could cause Fatigue and that some female patients may be more susceptible.
Electrolyte Imbalance, Asthma, Hypokalaemia, Dyspnoea, Fatigue, Productive Cough, Hypomagnesaemia

This Fatigue side effect was reported by a physician from UNITED STATES on Jan 05, 2011. A patient from UNITED STATES , weighting 251.1 lb, was treated with Promethazine-codeine Cough Syrup. Directly after treatment started, patient experienced the unwanted or unexpected Promethazine side effects: electrolyte imbalance, asthma, hypokalaemia, dyspnoea, fatigue, productive cough, hypomagnesaemia. Promethazine-codeine Cough Syrup dosage: NA.
Associated medications used:
  • Taxol (464 Mg)
  • Carboplatin (767 Mg)
  • Combivent
The patient was hospitalized. These side effects may potentially be related to Promethazine-codeine Cough Syrup.
Blood Pressure Fluctuation, Blood Pressure Systolic Decreased, Bone Marrow Disorder, Eye Rolling, Fatigue, Hallucination, Hyperhidrosis, Malaise, Nail Discolouration

This Fatigue side effect was reported by a consumer or non-health professional from UNITED STATES. A female patient (weight:NA) experienced the following symptoms/conditions: nausea. The patient was prescribed Promethazine Hcl Tablets, Usp (ngx) (dosage: 50 Mg, Once/single), which was started on Jun 15, 2010. Concurrently used drugs:
  • Insulin
  • Antihypertensives
When starting to take Promethazine Hcl Tablets, Usp (ngx) the consumer reported the following symptoms:
  • Blood Pressure Fluctuation
  • Blood Pressure Systolic Decreased
  • Bone Marrow Disorder
  • Eye Rolling
  • Fatigue
  • Hallucination
  • Hyperhidrosis
  • Malaise
  • Nail Discolouration
The patient was hospitalized. These side effects may potentially be related to Promethazine Hcl Tablets, Usp (ngx).
Blood Pressure Fluctuation, Blood Pressure Systolic Decreased, Bone Marrow Disorder, Eye Rolling, Fatigue, Hallucination, Hyperhidrosis, Malaise, Nail Discolouration

This Fatigue Promethazine Hcl Tablets, Usp (ngx) side effect was reported by a consumer or non-health professional from UNITED STATES on Jun 18, 2010. A Female , weighting 205.0 lb, was diagnosed with and was treated with Promethazine Hcl Tablets, Usp (ngx). The patient presented the following health conditions:
  • Blood Pressure Fluctuation
  • Blood Pressure Systolic Decreased
  • Bone Marrow Disorder
  • Eye Rolling
  • Fatigue
  • Hallucination
  • Hyperhidrosis
  • Malaise
  • Nail Discolouration
. Promethazine Hcl Tablets, Usp (ngx) dosage: 50 Mg, Once/single. Additional drugs used at the same time:
  • Insulin
  • Antihypertensives
The patient was hospitalized.
Abdominal Pain, Chest Pain, Chills, Contusion, Dyspnoea, Epistaxis, Fatigue, Haemolytic Anaemia, Headache

This is a Promethazine side effect report of a 35-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: nausea,vomiting,hepatitis c, who was treated with Promethazine (dosage:NA, start time: Sep 15, 2006), combined with: NA., and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Abdominal Pain
  • Chest Pain
  • Chills
  • Contusion
  • Dyspnoea
  • Epistaxis
  • Fatigue
  • Haemolytic Anaemia
  • Headache
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Promethazine treatment in female patients suffering from nausea,vomiting,hepatitis c, resulting in Fatigue.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Promethazine Fatigue Causes and Reviews


Everyone feels tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your Fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to Fatigue. These include

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme Fatigue is chronic Fatigue syndrome (CFS). This Fatigue is not the kind of tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging


Promethazine Fatigue Reviews

Wed, 04 Apr 2012

I got a Promethazine shot 4-5 weeks ago in my hip due to nausea and vomiting from a stomach virus. I now have a small lump-knot where I got the shot at and it is really sore still. I was told to massage it and put heat on it to make it go away but it doesn't help. Does this suppose to happen?

Wed, 17 Feb 2010
49 yo woman, regular medication Promethazine 50mg nocte for allergies. Commenced Mobic 15 mg 2/7 ago. Currently expereincing severe headaches, tiredness, blurred vision and sleep disturbance - eg vivid dreaming/ hallucinations. Are these known side effects?
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Promethazine Side Effects

Poisoning (63)
Toxicity To Various Agents (47)
Pain (45)
Nausea (37)
Completed Suicide (36)
Cardiac Arrest (36)
Cholecystitis Chronic (36)
Respiratory Arrest (34)
Confusional State (33)
Anxiety (27)
Vomiting (24)
Dyspnoea (24)
Exposure Via Ingestion (23)
Cholelithiasis (21)
Convulsion (21)
Injury (20)
Gallbladder Disorder (19)
Death (19)
Abdominal Pain (19)
Agitation (18)
Cardio-respiratory Arrest (18)
Dizziness (18)
Pain In Extremity (18)
Tremor (16)
Dystonia (16)
Diarrhoea (16)
Abdominal Pain Upper (15)
Dehydration (15)
Dyskinesia (15)
Mental Status Changes (15)
Headache (15)
Unresponsive To Stimuli (14)
Hallucination (14)
Emotional Distress (13)
Fatigue (13)
Hypotension (12)
Gait Disturbance (12)
Extrapyramidal Disorder (11)
Somnolence (11)
Oedema Peripheral (11)
Dysarthria (10)
Depression (10)
Deep Vein Thrombosis (10)
Burning Sensation (10)
Erythema (10)
Hypertension (10)
Pulmonary Embolism (10)
Lethargy (10)
Injection Site Pain (10)
Hypoaesthesia (10)

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