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Promethazine Headache Side Effects

Promethazine Headache Side Effect Reports


The following Promethazine Headache side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Headache, can occur, and what you can do about them.

A side effect could appear soon after you start Promethazine or it might take time to develop.



Headache, Visual Impairment, Hyperhidrosis, Nausea, Blood Pressure Increased, Presyncope

This Headache side effect was reported by a consumer or non-health professional from US. A 67-year-old female patient (weight:NA) experienced the following symptoms/conditions: vertigo. The patient was prescribed Promethazine (dosage: 25mg 1 Tab 4 To 6 Hrs. Po), which was started on Apr 05, 2013. Concurrently used drugs: NA. When starting to take Promethazine the consumer reported the following symptoms:
  • Headache
  • Visual Impairment
  • Hyperhidrosis
  • Nausea
  • Blood Pressure Increased
  • Presyncope
The patient was hospitalized. These side effects may potentially be related to Promethazine.
Nervousness, Feeling Abnormal, Anxiety, Abnormal Dreams, Headache, Agitation

This Headache Promethazine side effect was reported by a consumer or non-health professional from UNITED STATES on Feb 22, 2012. A male , weighting 324.1 lb, was diagnosed with and was treated with Promethazine. The patient presented the following health conditions:
  • Nervousness
  • Feeling Abnormal
  • Anxiety
  • Abnormal Dreams
  • Headache
  • Agitation
. Promethazine dosage: NA. Additional drugs used at the same time:
  • Aspirin (81 Mg, Unk)
  • Chantix (0.5 Mg, Daily)
  • Prilosec (20 Mg, 2x/day)
Headache, Diarrhoea, Toxicity To Various Agents, Decreased Appetite, Dehydration, Palpitations, Nausea

This is a Promethazine (promethazine) (25 Milligram, Tablets) (promethazine) side effect report of a 81-year-old female patient (weight:NA) from GERMANY, suffering from the following symptoms/conditions: NA, who was treated with Promethazine (promethazine) (25 Milligram, Tablets) (promethazine) (dosage:NA, start time: Jan 01, 2011), combined with:
  • Tramadol (tramadol) (50 Microgram, Capsules) (tramadol)
  • Esomeprazole (esomeprazole) (40 Milligram, Tablets) (esomeprazole)
  • Spiriva (tiotropium Bromide) (18 Microgram) (tiotropium Bromide)
  • Carbasalate (carbasalate) (100 Milligram, Tablets) (carbasalate)
  • Losartan W/ Hydrochlorothiazide (losartan, Hydrochlorothiazide) (table
  • Nitrazepam (nitrazepam) (5 Milligram, Tablets) (nitrazepam)
  • Nitroglycerine (glyceryl Trinitrate) (0.4 Milligram, Spray (not Inhala
  • Roflumilast (roflumilast) (500 Microgram, Tablets) (500 Mcg (500 Mcg, 1 In 1 D), Oral, 250 Mcg (250 Mcg, 1 In 1 D), Oral)
, and developed a serious reaction and a Headache side effect. The patient presented with:
  • Headache
  • Diarrhoea
  • Toxicity To Various Agents
  • Decreased Appetite
  • Dehydration
  • Palpitations
  • Nausea
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Promethazine (promethazine) (25 Milligram, Tablets) (promethazine) treatment in female patients suffering from NA, resulting in Headache.

Dyspnoea Exertional, Chest Pain, Blood Bilirubin Increased, Sickle Cell Anaemia With Crisis, Asthenia, Hypoxia, Back Pain, Headache, Pain In Extremity

A 45-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Promethazine Hydrochloride treatment (dosage: NA) on NS. Soon after starting Promethazine Hydrochloride treatment, the consumer experienced several side effects, including:
  • Dyspnoea Exertional
  • Chest Pain
  • Blood Bilirubin Increased
  • Sickle Cell Anaemia With Crisis
  • Asthenia
  • Hypoxia
  • Back Pain
  • Headache
  • Pain In Extremity
. Concurrently used drugs:
  • Methadone Hydrochloride
  • Oxygen (oxygen)
  • Spironolactone
  • Bupropion Hcl
  • Folic Acid
  • Ibuprofen
  • Vitamin D
  • Exjade (500 Mg, Bid, Oral)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Promethazine Hydrochloride side effects, such as Headache.
Substance Abuse, Headache

A female patient from UNITED STATES was prescribed and started Promethazine Hcl on Nov 25, 2011. Patient felt the following Promethazine side effects: substance abuse, headache Additional patient health information: Female , weighting 125.0 lb, The consumer reported the following symptoms: . Promethazine Hcl dosage: Unk. Concurrently used drugs:
  • Cannabis (Unk)
  • Morphine Sulfate (Unk)
  • Diazepam (Unk)
  • Temazepam (Unk)
Substance Abuse, Headache

This report suggests a potential Promethazine Hcl Headache side effect(s) that can have serious consequences. A female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Promethazine Hcl (dosage: Unk) starting NS. Soon after starting Promethazine Hcl the patient began experiencing various side effects, including:
  • Substance Abuse
  • Headache
Drugs used concurrently:
  • Morphine Sulfate (Unk)
  • Temazepam (Unk)
  • Cannabis (Unk)
  • Diazepam (Unk)
Although Promethazine Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Headache, may still occur.
Accidental Overdose, Substance Abuse, Headache, Toxicity To Various Agents

An adverse event was reported by a health professional on Nov 25, 2011 by a Female taking Promethazine Hcl (dosage: NA) . Location: UNITED STATES , weighting 125.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Promethazine side effects: accidental overdose, substance abuse, headache, toxicity to various agents. Additional medications/treatments:
Associated medications used:
  • Cannabis
  • Temazepam
  • Morphine Sulfate
  • Codeine
  • Diazepam
Abdominal Pain Upper, Chest Pain, Influenza Like Illness, Furuncle, Nausea, Diarrhoea, Headache, Nasal Congestion, Haemorrhage

This Headache problem was reported by a consumer or non-health professional from UNITED STATES. A female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Nov 20, 2010 a consumer started treatment with Promethazine (dosage: NA). The following drugs/medications were being taken at the same time:
  • Tramadol Hcl
  • Norvasc
  • Cimzia ((2 Shots Loading Dose Pfs Subcutaneous))
  • Amlodipine Besylate And Valsartan
  • Nebivolol
When commencing Promethazine, the patient experienced the following unwanted symptoms /side effects:
  • Abdominal Pain Upper
  • Chest Pain
  • Influenza Like Illness
  • Furuncle
  • Nausea
  • Diarrhoea
  • Headache
  • Nasal Congestion
  • Haemorrhage
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Anxiety, Fear, Motor Dysfunction, Hypoaesthesia, Speech Disorder, Headache, Panic Attack, Cerebrovascular Accident, Pain

This is a Promethazine side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Promethazine (dosage: NA) starting Nov 06, 2007. Concurrently used drugs:
  • Yaz (Unk)
  • Yasmin (1 Df (daily Dose), Qd, Oral)
  • Azithromycin
  • Yaz
Soon after that, the consumer experienced the following of symptoms:
  • Anxiety
  • Fear
  • Motor Dysfunction
  • Hypoaesthesia
  • Speech Disorder
  • Headache
  • Panic Attack
  • Cerebrovascular Accident
  • Pain
This opens a possibility that Promethazine could cause Headache and that some female patients may be more susceptible.
Convulsion, Headache, Hypertension, Tachycardia, Tachypnoea

This Headache side effect was reported by a pharmacist from UNITED STATES on May 12, 2008. A patient from UNITED STATES , 74 years of age, weighting 140.0 lb, was diagnosed with and was treated with Promethazine. Directly after treatment started, patient experienced the unwanted or unexpected Promethazine side effects: convulsion, headache, hypertension, tachycardia, tachypnoea. Promethazine dosage: 25 Mg Once Iv. These side effects may potentially be related to Promethazine.
Abdominal Pain, Chest Pain, Chills, Contusion, Dyspnoea, Epistaxis, Fatigue, Haemolytic Anaemia, Headache

This Headache side effect was reported by a consumer or non-health professional from UNITED STATES. A 35-year-old female patient (weight:NA) experienced the following symptoms/conditions: nausea,vomiting,hepatitis c. The patient was prescribed Promethazine (dosage: NA), which was started on Sep 15, 2006. Concurrently used drugs: NA. When starting to take Promethazine the consumer reported the following symptoms:
  • Abdominal Pain
  • Chest Pain
  • Chills
  • Contusion
  • Dyspnoea
  • Epistaxis
  • Fatigue
  • Haemolytic Anaemia
  • Headache
The patient was hospitalized. These side effects may potentially be related to Promethazine.
Amnesia, Asthenia, Clumsiness, Dyspnoea, Headache, Lethargy, Overdose, Pneumonia

This Headache Promethazine Hcl And Dextromethorphan Hbr side effect was reported by a consumer or non-health professional from on Mar 22, 2005. A male , 50 years of age, weighting 190.0 lb, was diagnosed with and was treated with Promethazine Hcl And Dextromethorphan Hbr. The patient presented the following health conditions:
  • Amnesia
  • Asthenia
  • Clumsiness
  • Dyspnoea
  • Headache
  • Lethargy
  • Overdose
  • Pneumonia
. Promethazine Hcl And Dextromethorphan Hbr dosage: 1-2 Tsp 4 Times A Day Orally. Additional drugs used at the same time:
  • Morphine
  • Sotalol Hcl
  • Lisinopril
  • Neurontin
  • Baclofen
  • Xanax
  • Gemfibrozil
  • Nexium
The patient was hospitalized.
Coma, Headache, Syncope, Tachycardia

This is a Promethazine side effect report of a 33-year-old female patient (weight:NA) from , suffering from the following symptoms/conditions: nausea, who was treated with Promethazine (dosage:12.5mg Every 3hrs Prn Intravenou, start time: Feb 05, 2005), combined with: NA., and developed a serious reaction and a Headache side effect. The patient presented with:
  • Coma
  • Headache
  • Syncope
  • Tachycardia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Promethazine treatment in female patients suffering from nausea, resulting in Headache.
Arm Amputation, Confusional State, Contrast Media Reaction, Headache, Nausea, Pain, Pain In Extremity, Vascular Occlusion

A 52-year-old female patient (weight: NA) from with the following symptoms: headache,nausea started Promethazine treatment (dosage: 25mg Prn Intravenou) on Nov 02, 2004. Soon after starting Promethazine treatment, the consumer experienced several side effects, including:
  • Arm Amputation
  • Confusional State
  • Contrast Media Reaction
  • Headache
  • Nausea
  • Pain
  • Pain In Extremity
  • Vascular Occlusion
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Promethazine side effects, such as Headache.
Burning Sensation, Headache, Infusion Site Reaction, Pain, Pain In Extremity, Peripheral Vascular Disorder, Poor Peripheral Circulation

A female patient from was prescribed and started Promethazine on Jan 03, 2005. After Promethazine was administered, patient encountered several Promethazine side effects: burning sensation, headache, infusion site reaction, pain, pain in extremity, peripheral vascular disorder, poor peripheral circulation Additional patient health information: Female , 52 years of age, weighting 107.0 lb, The consumer reported the following symptoms: was diagnosed with and. Promethazine dosage: 25mg Prn Intravenou. Concurrently used drugs: NA.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Promethazine Headache Causes and Reviews


Almost everyone has had a Headache. Headache is the most common form of pain. It's a major reason people miss days at work or school or visit the doctor.

The most common type of Headache is a tension Headache. Tension Headaches are due to tight muscles in your shoulders, neck, scalp and jaw. They are often related to stress, depression or anxiety. You are more likely to get tension Headaches if you work too much, don't get enough sleep, miss meals, or use alcohol.

Other common types of Headaches include migraines, cluster Headaches, and sinus Headaches. Most people can feel much better by making lifestyle changes, learning ways to relax and taking pain relievers.

Not all Headaches require a doctor's attention. But sometimes Headaches warn of a more serious disorder. Let your health care provider know if you have sudden, severe Headaches. Get medical help right away if you have a Headache after a blow to your head, or if you have a Headache along with a stiff neck, fever, confusion, loss of consciousness, or pain in the eye or ear.

NIH: National Institute of Neurological Disorders and Stroke


Promethazine Headache Reviews

Wed, 04 Apr 2012

I got a Promethazine shot 4-5 weeks ago in my hip due to nausea and vomiting from a stomach virus. I now have a small lump-knot where I got the shot at and it is really sore still. I was told to massage it and put heat on it to make it go away but it doesn't help. Does this suppose to happen?

Wed, 17 Feb 2010
49 yo woman, regular medication Promethazine 50mg nocte for allergies. Commenced Mobic 15 mg 2/7 ago. Currently expereincing severe Headaches, tiredness, blurred vision and sleep disturbance - eg vivid dreaming/ hallucinations. Are these known side effects?
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Pain (45)
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Abdominal Pain Upper (15)
Dehydration (15)
Dyskinesia (15)
Mental Status Changes (15)
Headache (15)
Unresponsive To Stimuli (14)
Hallucination (14)
Emotional Distress (13)
Fatigue (13)
Hypotension (12)
Gait Disturbance (12)
Extrapyramidal Disorder (11)
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Lethargy (10)
Injection Site Pain (10)
Hypoaesthesia (10)

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