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Promethazine Lethargy Side Effects

Promethazine Lethargy Side Effect Reports


The following Promethazine Lethargy side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Lethargy, can occur, and what you can do about them.

A side effect could appear soon after you start Promethazine or it might take time to develop.



Suicide Attempt, Lethargy, Dysarthria, Unresponsive To Stimuli, Hypotension, Bradycardia, Pupil Fixed, Peripheral Pulse Decreased, Hypoxia

This Lethargy side effect was reported by a physician from US. A 36-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Promethazine (dosage: Not The Prescribed Amount 4 To 6 Tablets, Oral), which was started on NS. Concurrently used drugs:
  • Metoprolol (Not The Prescribed Amount 10 To 12 Tablets, Oral)
  • Methamphetamine (not Specified) (Not The Prescribed Amount)
  • Alcohol (Not The Prescribed Amount, Oral)
  • Pregabalin (Not The Prescribed Amount 5 To 8 Capsules, Oral)
  • Meclizine /00072801/ (Not The Prescribed Amount 12 To 15 Tablets, Oral)
When starting to take Promethazine the consumer reported the following symptoms:
  • Suicide Attempt
  • Lethargy
  • Dysarthria
  • Unresponsive To Stimuli
  • Hypotension
  • Bradycardia
  • Pupil Fixed
  • Peripheral Pulse Decreased
  • Hypoxia
The patient was hospitalized. These side effects may potentially be related to Promethazine.
Nausea, Convulsion, Syncope, Dizziness, Lethargy

This Lethargy Promethazine side effect was reported by a consumer or non-health professional from UNITED STATES on Jan 05, 2012. A male , 82 years of age, was treated with Promethazine. The patient presented the following health conditions:
  • Nausea
  • Convulsion
  • Syncope
  • Dizziness
  • Lethargy
. Promethazine dosage: NA. Additional drugs used at the same time:
  • Synthroid
  • Exelon (Transdermal, 9.5 Mg/24 Hours, Transdermal)
  • Fludrocortisone Acetate
  • Aspirin
  • Fish Oil (fish Oil)
  • Simvastatin
  • Vitamins (ascorbic Acid, Ergocalciferol, Nicotinamide, Retinol, Ribofl
The patient was hospitalized.
Aggression, Lethargy, Initial Insomnia, Tension, Macrocytosis, C-reactive Protein Abnormal, Middle Insomnia, Cyclothymic Disorder, Muscle Atrophy

This is a Promethazine side effect report of a 60-year-old female patient (weight:NA) from UNITED KINGDOM, suffering from the following symptoms/conditions: anxiety, who was treated with Promethazine (dosage:50 Mg, Unk, start time: Jul 01, 2010), combined with:
  • Sertraline (100 Mg, Unk)
  • Atenolol (25 Mg, Qd)
  • Simvastatin (20 Mg, Qd)
  • Dosulepin (50 Mg, Qd)
  • Sertraline (150 Mg, Unk)
  • Lyrica (100 Mg, Tid)
  • Aspirin (75 Mg, Qd)
  • Sertraline (100 Mg, Qd)
, and developed a serious reaction and a Lethargy side effect. The patient presented with:
  • Aggression
  • Lethargy
  • Initial Insomnia
  • Tension
  • Macrocytosis
  • C-reactive Protein Abnormal
  • Middle Insomnia
  • Cyclothymic Disorder
  • Muscle Atrophy
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Promethazine treatment in female patients suffering from anxiety, resulting in Lethargy.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Bilirubin Increased, Jaundice, Lethargy

A 51-year-old patient (weight: NA) from UNITED STATES with the following symptoms: NA started Promethazine treatment (dosage: 25 Mg Prn Rectal) on Dec 26, 2008. Soon after starting Promethazine treatment, the consumer experienced several side effects, including:
  • Alanine Aminotransferase Increased
  • Aspartate Aminotransferase Increased
  • Blood Bilirubin Increased
  • Jaundice
  • Lethargy
. Concurrently used drugs:
  • Prochlorperazine (10 Mg Prn Po)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Promethazine side effects, such as Lethargy.
Dystonia, Lethargy, Mental Status Changes

A female patient from UNITED STATES was prescribed and started Promethazine on Dec 31, 2008. Patient felt the following Promethazine side effects: dystonia, lethargy, mental status changes Additional patient health information: Female , 91 years of age, weighting 169.8 lb, The consumer reported the following symptoms: was diagnosed with and. Promethazine dosage: 25mg Q6h Prn Im. Concurrently used drugs:
  • Lantus
  • Levothyroxine Sodium
  • Vasotec
  • Zantac
  • Lescol
  • Allegra
  • Detrol La
  • Aspirin
Asthenia, Chest Pain, Lethargy, Refusal Of Treatment By Patient

This report suggests a potential Promethazine Lethargy side effect(s) that can have serious consequences. A 76-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): catheter placement and used Promethazine (dosage: NA) starting NS. Soon after starting Promethazine the patient began experiencing various side effects, including:
  • Asthenia
  • Chest Pain
  • Lethargy
  • Refusal Of Treatment By Patient
Drugs used concurrently:
  • Oxycodone Hcl
  • Midazolam Hcl
  • Diazepam
  • Hydromorphone Hcl
Although Promethazine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Lethargy, may still occur.
Bradycardia, Hypoventilation, Lethargy

An adverse event was reported by a physician on Apr 04, 2005 by a Female taking Promethazine (dosage: Once) . Location: UNITED STATES , weighting 10.00 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Promethazine side effects: bradycardia, hypoventilation, lethargy. Additional medications/treatments:
Associated medications used:
  • Nubain
Lethargy, Respiratory Depression

This Lethargy problem was reported by a pharmacist from . A 68-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): nausea,vomiting.On May 05, 2005 a consumer started treatment with Promethazine (dosage: 25mg Q 6 Hours Prn Intravenous). The following drugs/medications were being taken at the same time: NA. When commencing Promethazine, the patient experienced the following unwanted symptoms /side effects:
  • Lethargy
  • Respiratory Depression
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Lethargy, may become evident only after a product is in use by the general population.
Amnesia, Asthenia, Clumsiness, Dyspnoea, Headache, Lethargy, Overdose, Pneumonia

This is a Promethazine Hcl And Dextromethorphan Hbr side effect report of a 50-year-old patient (weight: NA) from . The patient developed the following symptoms/conditions: cough and was treated with Promethazine Hcl And Dextromethorphan Hbr (dosage: 1-2 Tsp 4 Times A Day Orally) starting Mar 08, 2005. Concurrently used drugs:
  • Morphine
  • Sotalol Hcl
  • Lisinopril
  • Neurontin
  • Baclofen
  • Xanax
  • Gemfibrozil
  • Nexium
Soon after that, the consumer experienced the following of symptoms:
  • Amnesia
  • Asthenia
  • Clumsiness
  • Dyspnoea
  • Headache
  • Lethargy
  • Overdose
  • Pneumonia
The patient was hospitalized. This opens a possibility that Promethazine Hcl And Dextromethorphan Hbr could cause Lethargy and that some patients may be more susceptible.
Agitation, Bradycardia, Confusional State, Electrocardiogram T Wave Amplitude Increased, Hyperkalaemia, Hypotension, Lethargy

This Lethargy side effect was reported by a pharmacist from on Feb 23, 2005. A female patient from , 65 years of age, weighting 150.0 lb, was diagnosed with and was treated with Promethazine. Directly after treatment started, patient experienced the unwanted or unexpected Promethazine side effects: agitation, bradycardia, confusional state, electrocardiogram t wave amplitude increased, hyperkalaemia, hypotension, lethargy. Promethazine dosage: 12.5 Mg Every 4 H Prn Intravenou.
Associated medications used:
  • Haloperidol
  • Hydrocodone Bitartrate + Acetaminophen
  • Magnesium
  • Flumazenil
  • Folic Acid
  • Protonix
  • Sucralfate
  • Ibuprofen
The patient was hospitalized. These side effects may potentially be related to Promethazine.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Promethazine Lethargy Causes and Reviews


We are sorry, but no medical information on this topic currently exists in our database. Our articles are updated often, please revisit soon.


Promethazine Lethargy Reviews

Wed, 04 Apr 2012

I got a Promethazine shot 4-5 weeks ago in my hip due to nausea and vomiting from a stomach virus. I now have a small lump-knot where I got the shot at and it is really sore still. I was told to massage it and put heat on it to make it go away but it doesn't help. Does this suppose to happen?

Wed, 17 Feb 2010
49 yo woman, regular medication Promethazine 50mg nocte for allergies. Commenced Mobic 15 mg 2/7 ago. Currently expereincing severe headaches, tiredness, blurred vision and sleep disturbance - eg vivid dreaming/ hallucinations. Are these known side effects?
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Promethazine Side Effects

Poisoning (63)
Toxicity To Various Agents (47)
Pain (45)
Nausea (37)
Completed Suicide (36)
Cardiac Arrest (36)
Cholecystitis Chronic (36)
Respiratory Arrest (34)
Confusional State (33)
Anxiety (27)
Vomiting (24)
Dyspnoea (24)
Exposure Via Ingestion (23)
Cholelithiasis (21)
Convulsion (21)
Injury (20)
Gallbladder Disorder (19)
Death (19)
Abdominal Pain (19)
Agitation (18)
Cardio-respiratory Arrest (18)
Dizziness (18)
Pain In Extremity (18)
Tremor (16)
Dystonia (16)
Diarrhoea (16)
Abdominal Pain Upper (15)
Dehydration (15)
Dyskinesia (15)
Mental Status Changes (15)
Headache (15)
Unresponsive To Stimuli (14)
Hallucination (14)
Emotional Distress (13)
Fatigue (13)
Hypotension (12)
Gait Disturbance (12)
Extrapyramidal Disorder (11)
Somnolence (11)
Oedema Peripheral (11)
Dysarthria (10)
Depression (10)
Deep Vein Thrombosis (10)
Burning Sensation (10)
Erythema (10)
Hypertension (10)
Pulmonary Embolism (10)
Lethargy (10)
Injection Site Pain (10)
Hypoaesthesia (10)

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