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Xopenex 1.25 mg/3cc inhalation solution report #SELF-2313


Female patient reported the following Xopenex 1.25 mg/3cc inhalation solution side effect(s):Severe paradoxical bronchospasm following my routine maintenance nebulizer treatment with Xopenex 1.25 mg/3cc that resulted in a period of unconscienceness and a 5 day hospitalization.

12/15/2008 is just one of 8 episodes of paradoxical bronchospasm associated with xopenex nebulizer treatments during 2008 that resulted in ER treatment or hospital admission. The two most severe episodes were: 1. 6/2008 that resulted in hospitalization and a short period of ventilator supportort. 2. 12/2008 resulting in unconscienceness and a 5 day hospitalization Less severe worsening of asthma symptoms following xopenex nebulization has occurred and was treated with racepinephrine 2.25% and sq epinephrine.

Event date: Monday December 15th 12:00:00 AM
Dosage: one 1.25 mg/3cc unit dose treatment
Frequency: q 6 hours
Age: 56
Weight: 160
Other medications: theophylline, medrol advair, lipitor, lopid, effexor, trazadone, clonazapam, boneva,
Diagnosis: Severe persistent asthma
Pre-existing conditions: asthma and chronic bronchitis, previous paradoxical bronchospasm with albuterol and mucomyst
Hospitalized? Yes ER and 5 hospital days
Life-threatening? Yes 911 and ambulance transport
Disabled? No
Birth Defects? No
Was intervention required to prevent damage? Yes EMS, ER and in hospital
Other serious medical events? No
Died? No

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