There isn't enough space here to describe the difference in my life since I started Deplin three months ago. I lost a child two years ago so my depression has been severe. I take Deplin along with Celexa now. I have been able to quit eating hard core sugar (cakes, cookies, ice cream) which I was addicted to. I walked a half marathon (13.1 mile) this weekend. I'm a little sloppy around the house but have stopped being that way since taking Deplin. My relationships are better and I"m just overall so much happier. It has been a Godsend to me and I would not stop taking it. I have no bad side effects from it.