After just ONE monthly shot of 3.75mg Lupron Depot, I had immediate abdominal distention and still have it one year later. Very uncomfortable bloated feeling 24/7. I am only 95 pounds. CT scan reveals no fluid. Apparently the fluid retention went away but I was left with stretched out abdominal fascia. I never feel like myself anymore. I have to use my muscles to support my abdominal wall. Devastated. PLEASE email me at <a href="mailto:Jane.Goodhope.com">Jane.Goodhope at yahoo.com</a> if you have abdominal distention or permanent bloating long after taking Lupron. DON'T TAKE LUPRON EVEN ONCE !!!!!