Initially after approx 3 weeks hot flushes, irritability and anger left. Unfortunately after 3 months of use became extremely tired, weak, constant nausea, sleeplessness, abdominal pain but more worringly was fogginess of mind, memory affected. After trying to find out why I read info on side effects of Remifemmin. I had all symptoms and stopped immediately. 3 days later dramatic affect and no more symptoms.