I took Roaccutane over a year ago now, I suffered from very mild side effects (though still quite cringeworthy...) which were dryness of skin, especially around the mouth area, and one nose bleed (which i think was triggered by a nasty bash on the nose more than the drug ;) )
<b>After the first few weeks</b> my skin cleared up, I was amazed... I expected there to have been a period where my face would get worse before it started to clear up, but no... It started to clear up and dry out ASAP, so my dermitologist prescribed me the four month daily dosage and whatnot.
<b>Aftwe a month</b> leading up to a few weeks after I'd finished my skin was so dry, although it was only spring I couldn't go out into the sun too long, though I'd try to cram in 20 mins in the sun a day (just sat out in the garden) which really helped (even though I half expected it to dry my skin more) <b>I used an oil-free moisteriser throughout, right from week one</b> which eventually became my best friend.
It wasn't pretty, but it was worth it. Since then I've had spots here and there (like any normal person does) and odd breakouts here and there (which a course of antibiotics made quick work of).
Recently I had several outbreaks which spread and got worse, so I went to see my GP who suspected <b>impetigo</b> around the beard area, she said this is common when shaving over infected areas. I was prescribed <b>Floxacillin</b> along with my antibiotics, which comes to an attractive 2,500mg of antibiotics a day for a week, then 500mg from then on. Didn't feel great to be honest.
<b>I'd just like to say</b> my acne wasn't spread out like most acne, I'd get nasty cists and 'big ones' and haven't had any since. :) Still have battle scars, but they'll fade eventually ;).
Hope this helps at all, just remember to (for facial acne):
Wash your face in the mornings (after waking up), and in evenings (before bed, or after work/school).
Wash with warm soapy water first, then apply a liquid spot cleanser, then any sort of cream you find help (try new ones every time you run out to see which works best, but don't stick with the same one too long) wait 10 mins and use an <b>oil-free</b> moisturiser to stop your skin drying out. If you notice your skin is still oily/greasy or is moreso then stop using the moisturiser as often, let your skin dry out a tad and then start applying it (I found this helped for me anyway.)
Oral hygiene also helps, so brush regularly (this worked for me, anyway) = healthy gums is a good idea anyway.
Change your pillow cover quite regluarly, flipping it over and turning it inside out.
Shower daily if you can, washing your face in hot water/ steamy water is also very healhy for your skin (it opens your pores, be warned though... your face might get worse before it gets better).
Don't touch your face... get out of these habbits... it helps phenominally.
Your GP is your best friend, got to him/her for further advice (though with a 5 minute slot they might not be so much use).
<b>Anyone who bothered to read this - hope I helped :)</b>