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Simvastatin Liver Function Test Abnormal Side Effects

Simvastatin Liver Function Test Abnormal Side Effect Reports


The following Simvastatin Liver Function Test Abnormal side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Liver Function Test Abnormal, can occur, and what you can do about them.

A side effect could appear soon after you start Simvastatin or it might take time to develop.



Liver Function Test Abnormal, Blood Alkaline Phosphatase Increased, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased

This Liver Function Test Abnormal side effect was reported by a pharmacist from US. A 35-year-old female patient (weight:NA) experienced the following symptoms/conditions: hyperlipidaemia. The patient was prescribed Simvastatin (dosage: Simvastatin 40mg Tablet Po 8:30), which was started on NS. Concurrently used drugs:
  • Acetaminophen
  • Benzotropine
  • Duloxetine
  • Omeprazole
When starting to take Simvastatin the consumer reported the following symptoms:
  • Liver Function Test Abnormal
  • Blood Alkaline Phosphatase Increased
  • Aspartate Aminotransferase Increased
  • Alanine Aminotransferase Increased
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Hypotension, Sepsis, Liver Function Test Abnormal, Pyrexia

This Liver Function Test Abnormal Simvastatin side effect was reported by a physician from GB on Mar 31, 2014. A Female , 55 years of age, weighting 154.3 lb, was diagnosed with and was treated with Simvastatin. The patient presented the following health conditions:
  • Hypotension
  • Sepsis
  • Liver Function Test Abnormal
  • Pyrexia
. Simvastatin dosage: 80 Mg, Unk. Additional drugs used at the same time:
  • Baclofen
  • Ferrous Fumarate
  • Tizanidine Hydrochloride
  • Tolterodine
The patient was hospitalized.
Abnormal Loss Of Weight, Liver Function Test Abnormal

This is a Simvastatin side effect report of a 72-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: hyperlipidaemia, who was treated with Simvastatin (dosage:NA, start time: Mar 16, 2007), combined with:
  • Co-dydramol (paramol-118)
  • Folic Acid (folic Acid)
  • Mebeverine (mebeverine)
, and developed a serious reaction and a Liver Function Test Abnormal side effect. The patient presented with:
  • Abnormal Loss Of Weight
  • Liver Function Test Abnormal
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in female patients suffering from hyperlipidaemia, resulting in Liver Function Test Abnormal.

Abnormal Loss Of Weight, Liver Function Test Abnormal

A 72-year-old female patient (weight: NA) from GB with the following symptoms: hyperlipidaemia started Simvastatin treatment (dosage: Unk) on Mar 16, 2007. Soon after starting Simvastatin treatment, the consumer experienced several side effects, including:
  • Abnormal Loss Of Weight
  • Liver Function Test Abnormal
. Concurrently used drugs:
  • Co-dydramol (Unk)
  • Folic Acid (Unk)
  • Mebeverine (Unk)
This finding indicates that some patients can be more vulnerable to developing Simvastatin side effects, such as Liver Function Test Abnormal.
Liver Function Test Abnormal, Abnormal Loss Of Weight

A female patient from GB was prescribed and started Simvastatin on Sep 18, 2013. Patient felt the following Simvastatin side effects: liver function test abnormal, abnormal loss of weight Additional patient health information: Female , 72 years of age, weighting 124.6 lb, The consumer reported the following symptoms: was diagnosed with and. Simvastatin dosage: NA. Concurrently used drugs:
  • Co-dydramol
  • Folic Acid
  • Mebeverine
Abnormal Loss Of Weight, Liver Function Test Abnormal

This report suggests a potential Simvastatin Liver Function Test Abnormal side effect(s) that can have serious consequences. A 72-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): hyperlipidaemia and used Simvastatin (dosage: NA) starting Mar 16, 2007. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Abnormal Loss Of Weight
  • Liver Function Test Abnormal
Drugs used concurrently:
  • Co-dydramol
  • Folic Acid
  • Mebeverine
Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Liver Function Test Abnormal, may still occur.
Abnormal Loss Of Weight, Liver Function Test Abnormal

An adverse event was reported by a physician on Dec 03, 2013 by a Female taking Simvastatin (dosage: NA) was diagnosed with and. Location: GB , 72 years of age, weighting 124.6 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: abnormal loss of weight, liver function test abnormal. Additional medications/treatments:
Associated medications used:
  • Mebeverine
  • Co-dydramol
  • Folic Acid
Abnormal Loss Of Weight, Liver Function Test Abnormal

This Liver Function Test Abnormal problem was reported by a physician from GB. A 72-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): hyperlipidaemia.On Mar 16, 2007 a consumer started treatment with Simvastatin (dosage: NA). The following drugs/medications were being taken at the same time:
  • Folic Acid
  • Mebeverine
  • Co-dydramol
When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Abnormal Loss Of Weight
  • Liver Function Test Abnormal
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Liver Function Test Abnormal, may become evident only after a product is in use by the general population.
Abnormal Loss Of Weight, Liver Function Test Abnormal

This is a Simvastatin side effect report of a 72-year-old female patient (weight: NA) from GB. The patient developed the following symptoms/conditions: hyperlipidaemia and was treated with Simvastatin (dosage: NA) starting Mar 16, 2007. Concurrently used drugs:
  • Mebeverine
  • Co-dydramol
  • Folic Acid
Soon after that, the consumer experienced the following of symptoms:
  • Abnormal Loss Of Weight
  • Liver Function Test Abnormal
This opens a possibility that Simvastatin could cause Liver Function Test Abnormal and that some female patients may be more susceptible.
Abnormal Loss Of Weight, Liver Function Test Abnormal

This Liver Function Test Abnormal side effect was reported by a health professional from GB on Dec 05, 2013. A female patient from GB , 72 years of age, weighting 124.6 lb, was diagnosed with and was treated with Simvastatin. Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: abnormal loss of weight, liver function test abnormal. Simvastatin dosage: 40 Mg, Unk.
Associated medications used:
  • Mebeverine
  • Co-dydramol
  • Folic Acid
These side effects may potentially be related to Simvastatin.
Abnormal Loss Of Weight, Liver Function Test Abnormal

This Liver Function Test Abnormal side effect was reported by a physician from GB. A 72-year-old female patient (weight:NA) experienced the following symptoms/conditions: hyperlipidaemia. The patient was prescribed Simvastatin (dosage: 40 Mg, Unk), which was started on Mar 16, 2007. Concurrently used drugs:
  • Acetaminophen (+) Dihydrocodeine Bitartrate
  • Folic Acid
  • Mebeverine Hydrochloride
When starting to take Simvastatin the consumer reported the following symptoms:
  • Abnormal Loss Of Weight
  • Liver Function Test Abnormal
These side effects may potentially be related to Simvastatin.
Rhabdomyolysis, Liver Function Test Abnormal, Muscle Spasms

This Liver Function Test Abnormal Simvastatin side effect was reported by a health professional from US on Feb 19, 2013. A male , 52 years of age, was treated with Simvastatin. The patient presented the following health conditions:
  • Rhabdomyolysis
  • Liver Function Test Abnormal
  • Muscle Spasms
. Simvastatin dosage: 40 Mg, Qpm , Oral. Additional drugs used at the same time: NA. The patient was hospitalized.
Liver Function Test Abnormal

This is a Simvastatin side effect report of a 52-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: blood cholesterol increased, who was treated with Simvastatin (dosage:NA, start time: Mar 03, 2013), combined with: NA., and developed a serious reaction and a Liver Function Test Abnormal side effect. The patient presented with:
  • Liver Function Test Abnormal
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in female patients suffering from blood cholesterol increased, resulting in Liver Function Test Abnormal.
Myositis, Liver Function Test Abnormal

A 56-year-old patient (weight: NA) from GB with the following symptoms: NA started Simvastatin treatment (dosage: 40 Mg, Qd) on NS. Soon after starting Simvastatin treatment, the consumer experienced several side effects, including:
  • Myositis
  • Liver Function Test Abnormal
. Concurrently used drugs:
  • Clarithromycin (1 G, Qd)
  • Amiodarone (600 Mg, Qd)
  • Amiodarone (400 Mg, Qd)
  • Amiodarone (200 Mg, Qd)
  • Amiodarone (1.2 G, Qd)
  • Adenosine (Unk)
  • Aspirin (75 Mg, Qd)
  • Amlodipine (5 Mg, Qd)
This finding indicates that some patients can be more vulnerable to developing Simvastatin side effects, such as Liver Function Test Abnormal.
Dementia Alzheimer^s Type, Liver Function Test Abnormal

A female patient from GB was prescribed and started Simvastatin on Mar 30, 2013. After Simvastatin was administered, patient encountered several Simvastatin side effects: dementia alzheimer^s type, liver function test abnormal Additional patient health information: Female , 68 years of age, weighting 116.8 lb, The consumer reported the following symptoms: was diagnosed with and. Simvastatin dosage: At Night. Concurrently used drugs:
  • Flecainide
  • Anastrozole (Still On)
Fatigue, Diarrhoea, Hepatitis Acute, Liver Function Test Abnormal

This report suggests a potential Simvastatin Liver Function Test Abnormal side effect(s) that can have serious consequences. A 62-year-old patient from NO (weight:NA) was diagnosed with the following health condition(s): hypercholesterolaemia,pulmonary embolism and used Simvastatin (dosage: 1 In 1 D) starting NS. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Fatigue
  • Diarrhoea
  • Hepatitis Acute
  • Liver Function Test Abnormal
Drugs used concurrently:
  • Marevan
  • Diclofenac (diclofenac)
  • Selo-zok (metoprolol Succinate)
  • Adalat Oros (nifedipine)
  • Paracetamol (paracetamol)
The patient was hospitalized. Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Liver Function Test Abnormal, may still occur.
Alanine Aminotransferase Increased, Liver Function Test Abnormal

An adverse event was reported by a health professional on Feb 18, 2013 by a male taking Simvastatin (dosage: Unk) . Location: GB , 79 years of age, weighting 196.2 lb, patient began experiencing various side effects, including: Patient felt the following Simvastatin side effects: alanine aminotransferase increased, liver function test abnormal. Additional medications/treatments:
Liver Function Test Abnormal, Alanine Aminotransferase Increased

This Liver Function Test Abnormal problem was reported by a physician from GB. A 61-year-old patient (weight: NA) was diagnosed with the following medical condition(s): cholesterol high.On Nov 25, 2010 a consumer started treatment with Simvastatin (simvastatin) (dosage: NA). The following drugs/medications were being taken at the same time:
  • Amlodipine
  • Lansoprazole
When commencing Simvastatin (simvastatin), the patient experienced the following unwanted symptoms /side effects:
  • Liver Function Test Abnormal
  • Alanine Aminotransferase Increased
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Liver Function Test Abnormal, may become evident only after a product is in use by the general population.
Rhabdomyolysis, Liver Function Test Abnormal, Muscle Spasms

This is a Simvastatin Tablets, Usp side effect report of a 52-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Simvastatin Tablets, Usp (dosage: 40 Mg, Qpm) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Rhabdomyolysis
  • Liver Function Test Abnormal
  • Muscle Spasms
The patient was hospitalized. This opens a possibility that Simvastatin Tablets, Usp could cause Liver Function Test Abnormal and that some patients may be more susceptible.
Liver Function Test Abnormal, Pain In Extremity, Rhabdomyolysis, Blood Creatine Phosphokinase Increased

This Liver Function Test Abnormal side effect was reported by a physician from GERMANY on Jun 01, 2012. A patient from GERMANY , weighting 156.5 lb, was treated with Simvastatin. Patient felt the following Simvastatin side effects: liver function test abnormal, pain in extremity, rhabdomyolysis, blood creatine phosphokinase increased. Simvastatin dosage: NA.
Multiple prescriptions taken:
  • Brilinta
  • Aspirin
  • Metoprolol Tartrate
  • Ramipril
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Simvastatin Liver Function Test Abnormal Causes and Reviews


What is fatty liver disease?

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. Fatty liver disease is a condition in which fat builds up in your liver. There are two main types:

  • Nonalcoholic fatty liver disease (NAFLD)
  • Alcoholic fatty liver disease, also called alcoholic steatohepatitis
What is nonalcoholic fatty liver disease (NAFLD)?

NAFLD is a type of fatty liver disease that is not related to heavy alcohol use. There are two kinds:

  • Simple fatty liver, in which you have fat in your liver but little or no inflammation or liver cell damage. Simple fatty liver typically does not get bad enough to cause liver damage or complications.
  • Nonalcoholic steatohepatitis (NASH), in which you have inflammation and liver cell damage, as well as fat in your liver. Inflammation and liver cell damage can cause fibrosis, or scarring, of the liver. NASH may lead to cirrhosis or liver cancer.
What is alcoholic fatty liver disease?

Alcoholic fatty liver disease is due to heavy alcohol use. Your liver breaks down most of the alcohol you drink, so it can be removed from your body. But the process of breaking it down can generate harmful substances. These substances can damage liver cells, promote inflammation, and weaken your body's natural defenses. The more alcohol that you drink, the more you damage your liver. Alcoholic fatty liver disease is the earliest stage of alcohol-related liver disease. The next stages are alcoholic hepatitis and cirrhosis.

Who gets fatty liver disease?

Researchers do not know the cause of nonalcoholic fatty liver (NAFLD). They do know that it is more common in people who

  • Have type 2 diabetes and prediabetes
  • Have obesity
  • Are middle aged or older (although children can also get it)
  • Are Hispanic, followed by non-Hispanic whites. It is less common in African Americans.
  • Have high levels of fats in the blood, such as cholesterol and triglycerides
  • Have high blood pressure
  • Take certain drugs, such as corticosteroids and some cancer drugs
  • Have certain metabolic disorders, including metabolic syndrome
  • Have rapid weight loss
  • Have certain infections, such as hepatitis C
  • Have been exposed to some toxins

NAFLD affects about 25 percent of people in the world. As the rates of obesity, type 2 diabetes, and high cholesterol are rising in the United States, so is the rate of NAFLD. NAFLD is the most common chronic liver disorder in the United States.

Alcoholic fatty liver disease only happens in people who are heavy drinkers, especially those who have been drinking for a long period of time. The risk is higher for heavy drinkers who are women, have obesity, or have certain genetic mutations.

What are the symptoms of fatty liver disease?

Both NAFLD and alcoholic fatty liver disease are usually silent diseases with few or no symptoms. If you do have symptoms, you may feel tired or have discomfort in the upper right side of your abdomen.

How do I know if I have fatty liver disease?

Because there are often no symptoms, it is not easy to find fatty liver disease. Your doctor may suspect that you have it if you get abnormal results on liver tests that you had for other reasons. To make a diagnosis, your doctor will use

  • Your medical history
  • A physical exam
  • Various tests, including blood and imaging tests, and sometimes a biopsy

As part of the medical history, your doctor will ask about your alcohol use, to find out whether fat in your liver is a sign of alcoholic fatty liver disease or nonalcoholic fatty liver (NAFLD). He or she will also ask which medicines you take, to try to determine whether a medicine is causing your NAFLD.

During the physical exam, your doctor will examine your body and check your weight and height. Your doctor will look for signs of fatty liver disease, such as

  • An enlarged liver
  • Signs of cirrhosis, such as jaundice, a condition that causes your skin and whites of your eyes to turn yellow

You will likely have blood tests, including liver function tests and blood count tests. In some cases you may also have imaging tests, like those that check for fat in the liver and the stiffness of your liver. Liver stiffness can mean fibrosis, which is scarring of the liver. In some cases you may also need a liver biopsy to confirm the diagnosis, and to check how bad the liver damage is.

What are the treatments for fatty liver disease?

Doctors recommend weight loss for nonalcoholic fatty liver. Weight loss can reduce fat in the liver, inflammation, and fibrosis. If your doctor thinks that a certain medicine is the cause of your NAFLD, you should stop taking that medicine. But check with your doctor before stopping the medicine. You may need to get off the medicine gradually, and you might need to switch to another medicine instead.

There are no medicines that have been approved to treat NAFLD. Studies are investigating whether a certain diabetes medicine or Vitamin E can help, but more studies are needed.

The most important part of treating alcohol-related fatty liver disease is to stop drinking alcohol. If you need help doing that, you may want to see a therapist or participate in an alcohol recovery program. There are also medicines that can help, either by reducing your cravings or making you feel sick if you drink alcohol.

Both alcoholic fatty liver disease and one type of nonalcoholic fatty liver disease (nonalcoholic steatohepatitis) can lead to cirrhosis. Doctors can treat the health problems caused by cirrhosis with medicines, operations, and other medical procedures. If the cirrhosis leads to liver failure, you may need a liver transplant.

What are some lifestyle changes that can help with fatty liver disease?

If you have any of the types of fatty liver disease, there are some lifestyle changes that can help:

  • Eat a healthy diet, limiting salt and sugar, plus eating lots of fruits, vegetables, and whole grains
  • Get vaccinations for hepatitis A and B, the flu and pneumococcal disease. If you get hepatitis A or B along with fatty liver, it is more likely to lead to liver failure. People with chronic liver disease are more likely to get infections, so the other two vaccinations are also important.
  • Get regular exercise, which can help you lose weight and reduce fat in the liver
  • Talk with your doctor before using dietary supplements, such as vitamins, or any complementary or alternative medicines or medical practices. Some herbal remedies can damage your liver.

Simvastatin Liver Function Test Abnormal Reviews

Wed, 29 Sep 2010

I've been on a Simvastatin for 6 months. I broke out in a mysterious rash about a few weeks after I began it. I've had a rash ever since. 2 dermatologist and 1 allergist later, it is the opinion of 1 dermatologist and the allergist that my rash is resulting from the Simvastatin. My heart dr. has never seen anyone get a rash from a Simvastatin, but he is going to work with me. He wants me to be off of everything I take (vitamins also) for 6 weeks. If the rash disappears, we will begin to introduce each pill 1 week at a time. I itch everywhere. The rash is terrible. My dermatologist has me on Doxepin at night, an antihistimine in the day, and cortizone mousse. I still itch. I can't seem to find others that have experienced a rash from a Simvastatin. Please reply if you can sympathize.

Sat, 20 Feb 2010

I was recently diagnosed with high cholesterol level so started taking Simvastatin a week ago. Two weeks befroe that, my podiatrist prescribed diclofenac sodium for my plantar fasciitis for a month. Are these two drugs conter-indicated???? PLus I am experiencing diarrhea with rectal pain and not sure which is the cause.

Fri, 05 Nov 2010

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed to go for my Appt. The rash totally subsided. I call it off the Appt. I noticed 3 days ago the rash started again, it is itch but I try not to scratch. I want to see if the rash will takes three wk to subside. I will let you know.

Fri, 15 Jan 2010

Has anyone taking this medication after a year,expierenced headaches?

Wed, 04 May 2011

Please reply me. Thanks.,

Wed, 24 Nov 2010

I have been in Zorcor for a good 6 years with no problems (40mg). I did not have any problems until recently. I now have a number of strange complaintes. I thought it may just be part of getting older. I am having joint and muscle pain and extreme headaches that absolutely debiliatate
me. I have a rash and my throat swells at times.Until reading some of your comments, I never suspected it could be from the same med. The swellinng in the throat was the final straw. I am officially off the med. as of today, with an immediate doctor visit in the works.

Thu, 24 Feb 2011

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niacin is known to create rash in many people along with other side effects that are similar to Zocor. If you are taking niacine as well as Zocor I believe the combination may be the cause as I have tried stopping either and the rash dimenishes, ythough does not disappear. The reduction of fats in your blood may just be giving you abnormally dry skin resulting in the rash as it seems ceaseing either pill reduces my rash to the area around a very small mole.

Tue, 06 Apr 2010

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Simvastatin Side Effects

Rhabdomyolysis (1168)
Myalgia (1039)
Renal Failure Acute (504)
Fatigue (491)
Blood Creatine Phosphokinase Increased (489)
Pain In Extremity (449)
Muscular Weakness (445)
Asthenia (394)
Arthralgia (375)
Muscle Spasms (346)
Pain (328)
Dyspnoea (311)
Dizziness (304)
Nausea (281)
Fall (261)
Diarrhoea (257)
Gait Disturbance (243)
Alanine Aminotransferase Increased (241)
Headache (240)
Myositis (238)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Paraesthesia (126)
Hypoaesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Pruritus (107)
Cough (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Mobility Decreased (98)
Abasia (98)

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