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Simvastatin Malaise Side Effects

Simvastatin Malaise Side Effect Reports


The following Simvastatin Malaise side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Malaise, can occur, and what you can do about them.

A side effect could appear soon after you start Simvastatin or it might take time to develop.



Hypogammaglobulinaemia, Immune System Disorder, Malaise, Sinusitis, Nasopharyngitis, Infection, Injection Site Pain

This Malaise side effect was reported by a consumer or non-health professional from US. A 52-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Simvastatin (dosage: 5 Mg, Unk), which was started on 2001. Concurrently used drugs:
  • Lisinopril (5 Mg, Unk)
  • Enbrel (50 Mg, Weekly)
  • Vitamin C /00008001/ (500 Mg, Unk)
  • Prednisone (Unk)
  • Lexapro (5 Mg, Unk)
When starting to take Simvastatin the consumer reported the following symptoms:
  • Hypogammaglobulinaemia
  • Immune System Disorder
  • Malaise
  • Sinusitis
  • Nasopharyngitis
  • Infection
  • Injection Site Pain
These side effects may potentially be related to Simvastatin.
Blood Glucose Increased, White Blood Cell Count Increased, Myalgia, Arthralgia, Malaise

This Malaise Simvastatin side effect was reported by a consumer or non-health professional from GB on Oct 09, 2013. A male , 72 years of age, was treated with Simvastatin. The patient presented the following health conditions:
  • Blood Glucose Increased
  • White Blood Cell Count Increased
  • Myalgia
  • Arthralgia
  • Malaise
. Simvastatin dosage: NA. Additional drugs used at the same time:
  • Lisinopril
  • Amlodipine
  • Atenolol(atenolol)
  • Atorvastatin(atorvastatin)
  • Doxazosin(dozazosin)
  • Ranitidine(ranitidine)
Myalgia, Arthralgia, Malaise, Blood Glucose Increased, White Blood Cell Count Increased, Orthostatic Hypotension

This is a Simvastatin side effect report of a 72-year-old patient (weight:NA) from GB, suffering from the following symptoms/conditions: NA, who was treated with Simvastatin (dosage:At Night, start time: NS), combined with:
  • Lisinopril
  • Amlodipine
  • Ranitidine
  • Atenolol
  • Atorvastatin
  • Doxazosin (Increased From 2mg To 4mg Then Back To 2mg.)
, and developed a serious reaction and a Malaise side effect. The patient presented with:
  • Myalgia
  • Arthralgia
  • Malaise
  • Blood Glucose Increased
  • White Blood Cell Count Increased
  • Orthostatic Hypotension
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in patients suffering from NA, resulting in Malaise.

Coronary Artery Disease, Chronic Obstructive Pulmonary Disease, Chest Expansion Decreased, Malaise, Secretion Discharge

A 67-year-old patient (weight: NA) from BR with the following symptoms: dyslipidaemia,hypertension,coronary artery disease started Simvastatin treatment (dosage: 20 Mg, Qd) on 200601. Soon after starting Simvastatin treatment, the consumer experienced several side effects, including:
  • Coronary Artery Disease
  • Chronic Obstructive Pulmonary Disease
  • Chest Expansion Decreased
  • Malaise
  • Secretion Discharge
. Concurrently used drugs:
  • Losartan/hydrochlorothiazide (1 Df)
  • Acetylsalicylic Acid (100 Mg, Qd)
  • Clopidogrel (75 Mg, Qd)
This finding indicates that some patients can be more vulnerable to developing Simvastatin side effects, such as Malaise.
Myalgia, Arthralgia, Malaise, Blood Glucose Increased, White Blood Cell Count Increased

A patient from GB was prescribed and started Simvastatin on Oct 09, 2013. Patient felt the following Simvastatin side effects: myalgia, arthralgia, malaise, blood glucose increased, white blood cell count increased Additional patient health information: male , 72 years of age, The consumer reported the following symptoms: . Simvastatin dosage: At Night. Concurrently used drugs:
  • Amlodipine
  • Lisinopril
  • Atenolol
  • Ranitidine
  • Doxazosin (Increased From 2mg To 4mg Then Back To 2mg.)
Arthralgia, Myalgia, Malaise, White Blood Cell Count Increased, Blood Glucose Increased

This report suggests a potential Simvastatin Malaise side effect(s) that can have serious consequences. A 72-year-old patient from GB (weight:NA) was diagnosed with the following health condition(s): NA and used Simvastatin (dosage: NA) starting NS. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Arthralgia
  • Myalgia
  • Malaise
  • White Blood Cell Count Increased
  • Blood Glucose Increased
Drugs used concurrently:
  • Amlodipine
  • Lisinopril
  • Atenolol
  • Atorvastatin
  • Doxazosin
  • Ranitidine
Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Malaise, may still occur.
Blood Glucose Increased, White Blood Cell Count Increased, Myalgia, Arthralgia, Malaise

An adverse event was reported by a health professional on Oct 03, 2013 by a male taking Simvastatin (dosage: 40 Mg, At Night) . Location: GB , 72 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: blood glucose increased, white blood cell count increased, myalgia, arthralgia, malaise. Additional medications/treatments:
Associated medications used:
  • Lisinopril (40 Mg, Unk)
  • Amlodipine (5 Mg, Unk)
  • Ranitidine
  • Atenolol
  • Atorvastatin
  • Doxazosin (Increased From 2mg To 4mg Then Back To 2mg.)
Nasopharyngitis, Diarrhoea, Hepatic Steatosis, Malaise, Infection, Hepatomegaly, Muscle Spasms, Erythema

This Malaise problem was reported by a health professional from GB. A 64-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): blood cholesterol increased.On 2009 a consumer started treatment with Simvastatin (dosage: NA). The following drugs/medications were being taken at the same time:
  • Amlodipine
When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Nasopharyngitis
  • Diarrhoea
  • Hepatic Steatosis
  • Malaise
  • Infection
  • Hepatomegaly
  • Muscle Spasms
  • Erythema
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Malaise, may become evident only after a product is in use by the general population.
Disorientation, Malaise, Fatigue, Amnesia

This is a Simvastatin side effect report of a 68-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: hyperlipidaemia,hypertension and was treated with Simvastatin (dosage: NA) starting NS. Concurrently used drugs:
  • Amlodipine Besylate
  • Aspirin Ec
  • Benazepril(lotensin)
  • Hydrochlorothiazide(microzide)
  • Januvia
  • Metroformin
  • Glucophage Xr
  • Pioglitazone(actos)
Soon after that, the consumer experienced the following of symptoms:
  • Disorientation
  • Malaise
  • Fatigue
  • Amnesia
This opens a possibility that Simvastatin could cause Malaise and that some patients may be more susceptible.
Blister Infected, Malaise, Muscular Weakness, Diabetic Foot Infection

This Malaise side effect was reported by a pharmacist from GB on Sep 05, 2013. A female patient from GB , 74 years of age, was treated with Simvastatin. Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: blister infected, malaise, muscular weakness, diabetic foot infection. Simvastatin dosage: NA.
Associated medications used:
  • Clarithromycin
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Muscular Weakness, Malaise

This Malaise side effect was reported by a pharmacist from GB. A 74-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Simvastatin (dosage: 20 Milligram Daily;), which was started on NS. Concurrently used drugs:
  • Clarithromycin
When starting to take Simvastatin the consumer reported the following symptoms:
  • Muscular Weakness
  • Malaise
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Muscle Spasms, Urinary Tract Infection, Pain, Malaise, Impaired Driving Ability, Dry Eye, Economic Problem

This Malaise Simvastatin side effect was reported by a consumer or non-health professional from US on Aug 27, 2013. A Female , weighting 200.0 lb, was diagnosed with and was treated with Simvastatin. The patient presented the following health conditions:
  • Muscle Spasms
  • Urinary Tract Infection
  • Pain
  • Malaise
  • Impaired Driving Ability
  • Dry Eye
  • Economic Problem
. Simvastatin dosage: NA. Additional drugs used at the same time:
  • Oxycontin
  • Potassium Chloride
  • Ranitidine
  • Sertaline
  • Sitagliptin
  • Warfarin
  • Albuterol Inhaler
  • Calcium-vitamin
Muscular Weakness, Malaise

This is a Simvastatin side effect report of a 74-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: NA, who was treated with Simvastatin (dosage:20 Mg, Qd, start time: NS), combined with:
  • Clarithromycin (Unk)
, and developed a serious reaction and a Malaise side effect. The patient presented with:
  • Muscular Weakness
  • Malaise
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in female patients suffering from NA, resulting in Malaise.
Muscular Weakness, Malaise

A 74-year-old female patient (weight: NA) from GB with the following symptoms: NA started Simvastatin treatment (dosage: 20 Mg, Qd) on NS. Soon after starting Simvastatin treatment, the consumer experienced several side effects, including:
  • Muscular Weakness
  • Malaise
. Concurrently used drugs:
  • Clarithromycin
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Simvastatin side effects, such as Malaise.
Cold Sweat, Muscle Spasms, Dizziness, Anxiety, Derealisation, Feeling Abnormal, Malaise, Headache

A female patient from GB was prescribed and started Simvastatin on Aug 16, 2013. After Simvastatin was administered, patient encountered several Simvastatin side effects: cold sweat, muscle spasms, dizziness, anxiety, derealisation, feeling abnormal, malaise, headache Additional patient health information: Female , 81 years of age, weighting 132.9 lb, The consumer reported the following symptoms: was diagnosed with and. Simvastatin dosage: 20 Mg, Qd. Concurrently used drugs:
  • Aspirin (75 Mg, Qd)
  • Candesartan (1 Df, Qd)
  • Ivabradine (0.5 Df, Bid)
  • Lansoprazole (1 Df, Qd)
  • Levothyroxine Sodium (25 Microgram, Qd)
  • Levothyroxine Sodium (50 Microgram, Qd)
  • Serevent (2 Df, Bid)
  • Ventolin (albuterol) (Unk, Prn)
Headache, Dizziness, Cold Sweat, Malaise, Sleep Disorder, Feeling Abnormal, Anxiety, Derealisation

This report suggests a potential Simvastatin Malaise side effect(s) that can have serious consequences. A 81-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): hypercholesterolaemia and used Simvastatin (dosage: NA) starting NS. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Headache
  • Dizziness
  • Cold Sweat
  • Malaise
  • Sleep Disorder
  • Feeling Abnormal
  • Anxiety
  • Derealisation
Drugs used concurrently:
  • Aspirin (acetylsalicylic Acid)
  • Candesartan (candesartan)
  • Ivabradine (ivavradine)
  • Lansoprazole (lansoprazole)
  • Levothyroxine (levothyroxine)
  • Serevent (salmeterol Xinafoate)
  • Ventolin (salbutamol)
Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Malaise, may still occur.
Cold Sweat, Muscle Spasms, Dizziness, Anxiety, Derealisation, Feeling Abnormal, Malaise, Headache

An adverse event was reported by a health professional on Aug 14, 2013 by a Female taking Simvastatin (dosage: 20 Mg, Qd) was diagnosed with and. Location: GB , 81 years of age, weighting 132.9 lb, patient began experiencing various side effects, including: Patient felt the following Simvastatin side effects: cold sweat, muscle spasms, dizziness, anxiety, derealisation, feeling abnormal, malaise, headache. Additional medications/treatments:
Multiple prescriptions taken:
  • Aspirin (75 Mg, Qd)
  • Candesartan (1 Df, Qd)
  • Ivabradine (0.5 Df, Bid)
  • Lansoprazole (1 Df, Qd)
  • Levothyroxine (50 ?g, Qd)
  • Levothyroxine (25 U/g, Qd)
  • Serevent (2 Df, Bid)
  • Ventolin (As Necessary)
Anxiety, Sleep Disorder, Cold Sweat, Muscle Spasms, Dizziness, Derealisation, Feeling Abnormal, Malaise

This Malaise problem was reported by a health professional from GB. A 81-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): hypercholesterolaemia.On NS a consumer started treatment with Simvastatin (dosage: NA). The following drugs/medications were being taken at the same time:
  • Aspirin
  • Candesartan
  • Ivabradine
  • Lansoprazole
  • Levothyroxine
  • Levothyroxine
  • Serevent
  • Ventolin
When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Anxiety
  • Sleep Disorder
  • Cold Sweat
  • Muscle Spasms
  • Dizziness
  • Derealisation
  • Feeling Abnormal
  • Malaise
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Malaise, may become evident only after a product is in use by the general population.
Dysphonia, Influenza Like Illness, Chest Discomfort, Dyspnoea, Swelling Face, Malaise, Pyrexia

This is a Simvastatin side effect report of a 58-year-old female patient (weight: NA) from GB. The patient developed the following symptoms/conditions: blood cholesterol increased and was treated with Simvastatin (dosage: 20 Mg, Unk) starting Aug 08, 2012. Concurrently used drugs:
  • Lansoprazole
  • Betahistine
  • Fluoxetine
  • Livial
  • Mirtazapine
  • Thyroxine
  • Paracetamol
Soon after that, the consumer experienced the following of symptoms:
  • Dysphonia
  • Influenza Like Illness
  • Chest Discomfort
  • Dyspnoea
  • Swelling Face
  • Malaise
  • Pyrexia
This opens a possibility that Simvastatin could cause Malaise and that some female patients may be more susceptible.
Anaemia, Liver Disorder, Renal Impairment, Fatigue, Malaise, Nausea, Dizziness

This Malaise side effect was reported by a health professional from SE on Jul 18, 2013. A female patient from SE , 69 years of age, was treated with Simvastatin. Patient felt the following Simvastatin side effects: anaemia, liver disorder, renal impairment, fatigue, malaise, nausea, dizziness. Simvastatin dosage: Unk.
Multiple prescriptions taken:
  • Enalapril Comp Ratiopharm (Unk)
These side effects may potentially be related to Simvastatin.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Simvastatin Malaise Causes and Reviews


What is chronic fatigue syndrome?

Chronic fatigue syndrome (CFS) is a serious, long-term illness that affects many body systems. Another name for it is myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). CFS can often make you unable to do your usual activities. Sometimes you may not even be able to get out of bed.

What are the symptoms of chronic fatigue syndrome?

CFS symptoms can include

  • Severe fatigue that is not improved by rest
  • Sleep problems
  • Post-exertional Malaise (PEM), where your symptoms get worse after any physical or mental activity
  • Problems with thinking and concentrating
  • Pain
  • Dizziness

CFS can be unpredictable. Your symptoms may come and go. They may change over time - sometimes they might get better, and other times they may get worse.

Who gets chronic fatigue syndrome?

Anyone can get CFS, but it is most common in people between 40 and 60 years old. Adult women have it more often that adult men. Whites are more likely than other races to get a diagnosis of CFS, but many people with CFS have not been diagnosed with it.

What causes chronic fatigue syndrome?

Scientists don't know what causes CFS. There may be more than one thing that causes it. It is possible that two or more triggers might work together to cause the illness.

How is chronic fatigue syndrome diagnosed?

CFS can be difficult to diagnose. There are no tests for it, and other illnesses can cause similar symptoms. Your health care provider has to rule out other diseases before making a diagnosis of CFS. He or she will do a thorough medical exam, including

  • Asking about your health history and your family's medical history
  • Asking about your current illness, including your symptoms. Your doctor will want to know how often you have symptoms, how bad they are, how long they have lasted, and how they affect your life.
  • A thorough physical and mental status exam
  • Blood, urine or other tests
What are the treatments for chronic fatigue syndrome?

There is no cure or approved treatment for CFS, but you may be able to treat or manage some of your symptoms. You, your family, and your health care provider should work together to decide on a plan. You should figure out which symptom causes the most problems, and try to treat that first. For example, if sleep problems affect you the most, you might first try using good sleep habits. If those do not help, you may need to take medicines or see a sleep specialist.

Strategies such as learning new ways to manage activity can also be helpful. You need to make sure that you do not "push and crash." This can happen when you feel better, do too much, and then get worse again.

Since the process of developing a treatment plan and attending to self-care can be hard if you have CFS, it is important to have support from family members and friends.

Don't try any new treatments without talking to your health care provider. Some treatments that are promoted as cures for CFS are unproven, often costly, and could be dangerous.

Centers for Disease Control and Prevention


Simvastatin Malaise Reviews

Wed, 29 Sep 2010

I've been on a Simvastatin for 6 months. I broke out in a mysterious rash about a few weeks after I began it. I've had a rash ever since. 2 dermatologist and 1 allergist later, it is the opinion of 1 dermatologist and the allergist that my rash is resulting from the Simvastatin. My heart dr. has never seen anyone get a rash from a Simvastatin, but he is going to work with me. He wants me to be off of everything I take (vitamins also) for 6 weeks. If the rash disappears, we will begin to introduce each pill 1 week at a time. I itch everywhere. The rash is terrible. My dermatologist has me on Doxepin at night, an antihistimine in the day, and cortizone mousse. I still itch. I can't seem to find others that have experienced a rash from a Simvastatin. Please reply if you can sympathize.

Sat, 20 Feb 2010

I was recently diagnosed with high cholesterol level so started taking Simvastatin a week ago. Two weeks befroe that, my podiatrist prescribed diclofenac sodium for my plantar fasciitis for a month. Are these two drugs conter-indicated???? PLus I am experiencing diarrhea with rectal pain and not sure which is the cause.

Fri, 05 Nov 2010

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed to go for my Appt. The rash totally subsided. I call it off the Appt. I noticed 3 days ago the rash started again, it is itch but I try not to scratch. I want to see if the rash will takes three wk to subside. I will let you know.

Fri, 15 Jan 2010

Has anyone taking this medication after a year,expierenced headaches?

Wed, 04 May 2011

Please reply me. Thanks.,

Wed, 24 Nov 2010

I have been in Zorcor for a good 6 years with no problems (40mg). I did not have any problems until recently. I now have a number of strange complaintes. I thought it may just be part of getting older. I am having joint and muscle pain and extreme headaches that absolutely debiliatate
me. I have a rash and my throat swells at times.Until reading some of your comments, I never suspected it could be from the same med. The swellinng in the throat was the final straw. I am officially off the med. as of today, with an immediate doctor visit in the works.

Thu, 24 Feb 2011

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niacin is known to create rash in many people along with other side effects that are similar to Zocor. If you are taking niacine as well as Zocor I believe the combination may be the cause as I have tried stopping either and the rash dimenishes, ythough does not disappear. The reduction of fats in your blood may just be giving you abnormally dry skin resulting in the rash as it seems ceaseing either pill reduces my rash to the area around a very small mole.

Tue, 06 Apr 2010

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Simvastatin Side Effects

Rhabdomyolysis (1169)
Myalgia (1039)
Renal Failure Acute (504)
Fatigue (491)
Blood Creatine Phosphokinase Increased (489)
Pain In Extremity (449)
Muscular Weakness (445)
Asthenia (394)
Arthralgia (375)
Muscle Spasms (346)
Pain (328)
Dyspnoea (311)
Dizziness (304)
Nausea (281)
Fall (261)
Diarrhoea (257)
Gait Disturbance (243)
Alanine Aminotransferase Increased (241)
Headache (240)
Myositis (238)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Paraesthesia (126)
Hypoaesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Pruritus (107)
Cough (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Mobility Decreased (98)
Abasia (98)

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