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Simvastatin Renal Failure Side Effects

Simvastatin Renal Failure Side Effect Reports


The following Simvastatin Renal Failure side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Renal Failure, can occur, and what you can do about them.

A side effect could appear soon after you start Simvastatin or it might take time to develop.



Hypotension, Nausea, Vomiting, Diarrhoea, Metabolic Acidosis, Rhabdomyolysis, Renal Tubular Necrosis, Renal Failure, Lung Infiltration

This Renal Failure side effect was reported by a physician from COUNTRY NOT SPECIFIED. A 24-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Simvastatin (dosage: NA), which was started on NS. Concurrently used drugs:
  • Amlodipine Besylate (400 To 600 Mg)
  • Trazodone
  • Sertraline
When starting to take Simvastatin the consumer reported the following symptoms:
  • Hypotension
  • Nausea
  • Vomiting
  • Diarrhoea
  • Metabolic Acidosis
  • Rhabdomyolysis
  • Renal Tubular Necrosis
  • Renal Failure
  • Lung Infiltration
These side effects may potentially be related to Simvastatin.
Pancytopenia, Condition Aggravated, Granulomatous Liver Disease, Cholestasis, Renal Failure, Pyrexia, Apparent Life Threatening Event, Tooth Avulsion, Haemorrhage

This Renal Failure Simvastatin side effect was reported by a health professional from FR on Oct 08, 2013. A male , 70 years of age, was treated with Simvastatin. The patient presented the following health conditions:
  • Pancytopenia
  • Condition Aggravated
  • Granulomatous Liver Disease
  • Cholestasis
  • Renal Failure
  • Pyrexia
  • Apparent Life Threatening Event
  • Tooth Avulsion
  • Haemorrhage
. Simvastatin dosage: NA. Additional drugs used at the same time:
  • Amlor
  • Lyrica
  • Intelence
  • Isentress
  • Nisisco
  • Kardegic
  • Tardyferon
  • Movicol
The patient was hospitalized.
Pancytopenia, Renal Failure, Granulomatous Liver Disease, Cholestasis, Pyrexia, Tooth Avulsion, Angina Pectoris, Myelodysplastic Syndrome

This is a Simvastatin side effect report of a 70-year-old patient (weight:NA) from FR, suffering from the following symptoms/conditions: NA, who was treated with Simvastatin (dosage:Unk, start time: NS), combined with:
  • Amlor (Unk)
  • Lyrica (Unk)
  • Intelence (Unk)
  • Isentress (Unk)
  • Nisisco (Unk)
  • Kardegic (Unk)
  • Tardyferon (Unk)
  • Movicol (Unk)
, and developed a serious reaction and a Renal Failure side effect. The patient presented with:
  • Pancytopenia
  • Renal Failure
  • Granulomatous Liver Disease
  • Cholestasis
  • Pyrexia
  • Tooth Avulsion
  • Angina Pectoris
  • Myelodysplastic Syndrome
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in patients suffering from NA, resulting in Renal Failure.

Myalgia, Renal Failure, Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased

A 80-year-old female patient (weight: NA) from NO with the following symptoms: NA started Simvastatin (simvastatin) treatment (dosage: NA) on 201212. Soon after starting Simvastatin (simvastatin) treatment, the consumer experienced several side effects, including:
  • Myalgia
  • Renal Failure
  • Blood Creatine Phosphokinase Increased
  • Alanine Aminotransferase Increased
  • Aspartate Aminotransferase Increased
. Concurrently used drugs:
  • Erythromycin (erythromycin)
  • Prednisolon
  • Atacand Plus (blopress Plus)
  • Furix (furosemide)
  • Metoprolol Sandoz (metoprolol Tartrate)
  • Marevan (warfarin Sodium)
  • Zanidip (lercanidipine Hydrochloride)
  • Calcigran Forte (lekovit Ca)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Simvastatin (simvastatin) side effects, such as Renal Failure.
Renal Failure, Brain Injury, Cardiac Failure, Incorrect Dose Administered

A patient from US was prescribed and started Simvastatin on Sep 13, 2012. Patient felt the following Simvastatin side effects: renal failure, brain injury, cardiac failure, incorrect dose administered Additional patient health information: male , weighting 200.0 lb, The consumer reported the following symptoms: was diagnosed with and. Simvastatin dosage: 80 Mg. 1 Daily. Concurrently used drugs:
  • Amlodpine (10 Mg 1 Daily)
The patient was hospitalized and became disabled.
Pancreatitis Necrotising, Intestinal Perforation, Renal Failure, Haemodialysis, Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, White Blood Cell Count Increased

This report suggests a potential Simvastatin Renal Failure side effect(s) that can have serious consequences. A 53-year-old patient from COUNTRY NOT SPECIFIED (weight:NA) was diagnosed with the following health condition(s): NA and used Simvastatin (dosage: At Night (40 Mg, 1 In 1 D), Oral) starting Apr 01, 2011. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Pancreatitis Necrotising
  • Intestinal Perforation
  • Renal Failure
  • Haemodialysis
  • Alanine Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
  • White Blood Cell Count Increased
Drugs used concurrently:
  • Aspirin
  • Bisoprolol Fumarate
  • Clopidogrel
  • Ramipril
The patient was hospitalized. Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Renal Failure, may still occur.
Pancreatitis Necrotising, Intestinal Perforation, Renal Failure

An adverse event was reported by a pharmacist on Oct 08, 2012 by a male taking Simvastatin (dosage: NA) . Location: GB , 53 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: pancreatitis necrotising, intestinal perforation, renal failure. Additional medications/treatments:
Associated medications used:
  • Aspirin
  • Bisoprolol
  • Clopidogrel
  • Ramipril
The patient was hospitalized.
Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Intestinal Perforation, Blood Creatinine Increased, Pancreatitis Necrotising, Renal Failure, White Blood Cell Count Increased

This Renal Failure problem was reported by a pharmacist from GB. A 53-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Apr 01, 2011 a consumer started treatment with Simvastatin (dosage: 40 Mg, Qd). The following drugs/medications were being taken at the same time:
  • Aspirin (75 Mg, 1 Days)
  • Bisoprolol (2.5 Mg, 1 Days)
  • Clopidogrel (75 Mg, 1 Days)
  • Ramipril (2.5 Mg, 1 Days)
When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Alanine Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
  • Intestinal Perforation
  • Blood Creatinine Increased
  • Pancreatitis Necrotising
  • Renal Failure
  • White Blood Cell Count Increased
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Renal Failure, may become evident only after a product is in use by the general population.
Pancreatitis Necrotising, Renal Failure, Intestinal Perforation

This is a Simvastatin side effect report of a 53-year-old patient (weight: NA) from GB. The patient developed the following symptoms/conditions: NA and was treated with Simvastatin (dosage: At Night) starting Apr 01, 2011. Concurrently used drugs:
  • Bisoprolol
  • Ramipril
  • Aspirin
  • Clopidogrel
Soon after that, the consumer experienced the following of symptoms:
  • Pancreatitis Necrotising
  • Renal Failure
  • Intestinal Perforation
The patient was hospitalized. This opens a possibility that Simvastatin could cause Renal Failure and that some patients may be more susceptible.
Pancreatitis Necrotising, Renal Failure, Intestinal Perforation, Blood Creatinine Increased, Blood Alkaline Phosphatase Increased, White Blood Cell Count Increased, Alanine Aminotransferase Increased

This Renal Failure side effect was reported by a pharmacist from GB on Oct 04, 2012. A patient from GB , 53 years of age, was treated with Simvastatin. Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: pancreatitis necrotising, renal failure, intestinal perforation, blood creatinine increased, blood alkaline phosphatase increased, white blood cell count increased, alanine aminotransferase increased. Simvastatin dosage: 40 Milligram Daily; At Night.
Associated medications used:
  • Bisoprolol
  • Ramipril
  • Aspirin
  • Clopidogrel
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Urinary Tract Infection, Renal Failure

This Renal Failure side effect was reported by a consumer or non-health professional from BR. A 78-year-old female patient (weight:NA) experienced the following symptoms/conditions: blood cholesterol increased,hypertension. The patient was prescribed Simvastatin (dosage: 40 Mg, Unk), which was started on 2002. Concurrently used drugs:
  • Captopril (Unk, Tid)
  • Liptor (10 Mg, Qd)
When starting to take Simvastatin the consumer reported the following symptoms:
  • Urinary Tract Infection
  • Renal Failure
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Intestinal Perforation, Pancreatitis Necrotising, Renal Failure, Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, White Blood Cell Count Increased

This Renal Failure Simvastatin side effect was reported by a health professional from GB on Sep 26, 2012. A male , 53 years of age, was treated with Simvastatin. The patient presented the following health conditions:
  • Intestinal Perforation
  • Pancreatitis Necrotising
  • Renal Failure
  • Alanine Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
  • White Blood Cell Count Increased
. Simvastatin dosage: 40 Mg, Qd. Additional drugs used at the same time:
  • Aspirin (75 Mg, Qd)
  • Bisoprolol (2.5 Mg, Qd)
  • Clopidogrel (75 Mg, Qd)
  • Ramipril (2.5 Mg, Qd)
The patient was hospitalized.
Renal Failure, Blood Creatinine Increased

This is a Simvastatin side effect report of a female patient (weight:NA) from , suffering from the following symptoms/conditions: NA, who was treated with Simvastatin (dosage:20 Mg Daily, start time: May 21, 2010), combined with:
  • Nitrendipin (20 Mg Daily, Twice Daily)
  • Doxazosin Mesylate (2 Mg Daily)
  • Zemplar
  • Levothyroxine
  • Furosemide (40 Mg Daily)
  • Aspirin (100 Mg Daily)
  • Olmesartan Medoxomil (20 Mg Daily)
  • Zemplar (1 Mcg Daily)
, and developed a serious reaction and a Renal Failure side effect. The patient presented with:
  • Renal Failure
  • Blood Creatinine Increased
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in female patients suffering from NA, resulting in Renal Failure.
Compartment Syndrome, Mental Status Changes, Procedural Pain, Liver Function Test Abnormal, Sepsis, Erythema, Toxicity To Various Agents, Renal Failure, Oedema

A 52-year-old patient (weight: NA) from UNITED STATES with the following symptoms: NA started Simvastatin treatment (dosage: NA) on NS. Soon after starting Simvastatin treatment, the consumer experienced several side effects, including:
  • Compartment Syndrome
  • Mental Status Changes
  • Procedural Pain
  • Liver Function Test Abnormal
  • Sepsis
  • Erythema
  • Toxicity To Various Agents
  • Renal Failure
  • Oedema
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Simvastatin side effects, such as Renal Failure.
Back Pain, Multi-organ Failure, Muscular Weakness, Rhabdomyolysis, Renal Failure, Arthralgia

A female patient from GREECE was prescribed and started Simvastatin on Apr 15, 2009. After Simvastatin was administered, patient encountered several Simvastatin side effects: back pain, multi-organ failure, muscular weakness, rhabdomyolysis, renal failure, arthralgia Additional patient health information: Female , weighting 121.3 lb, The consumer reported the following symptoms: was diagnosed with and. Simvastatin dosage: NA. Concurrently used drugs:
  • Alvefco
  • Alvefco
  • Olartan
  • Nitrong
  • Controlloc
  • Spiriva
  • Carvedilol
  • Salospir
The patient was hospitalized.
Renal Failure, Skin Exfoliation, Fall, Hypovolaemia, Head Injury, Contusion, Gait Disturbance, Urinary Retention, Insomnia

This report suggests a potential Simvastatin Renal Failure side effect(s) that can have serious consequences. A 45-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): blood cholesterol,hypothyroidism,depression and used Simvastatin (dosage: NA) starting Jan 09, 2009. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Renal Failure
  • Skin Exfoliation
  • Fall
  • Hypovolaemia
  • Head Injury
  • Contusion
  • Gait Disturbance
  • Urinary Retention
  • Insomnia
Drugs used concurrently:
  • Synthroid
  • Remeron
The patient was hospitalized. Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Renal Failure, may still occur.
Hypertensive Crisis, Renal Failure, Chronic Obstructive Pulmonary Disease

An adverse event was reported by a physician on Feb 20, 2012 by a Female taking Simvastatin (dosage: 40 Mg, Qd) was diagnosed with and. Location: GERMANY , weighting 156.5 lb, patient began experiencing various side effects, including: Patient felt the following Simvastatin side effects: hypertensive crisis, renal failure, chronic obstructive pulmonary disease. Additional medications/treatments:
Multiple prescriptions taken:
  • Rasilez Hct (300/25 Mg Daily)
  • Amlodipine
  • Diuretics
  • Pentaerythritol Tetranitrate (50 Mg, Qd)
  • Torsemide (20 Mg, Qd)
  • Lercanidipine (10 Mg, Qd)
  • Rasilez Hct (1 Df, Qd)
  • Ace Inhibitor Nos (10 Mg, Daily)
The patient was hospitalized.
Lymphatic Disorder, Myalgia, Mass, Renal Failure

This Renal Failure problem was reported by a consumer or non-health professional from UNITED STATES. A 52-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): blood cholesterol increased.On Jan 27, 2012 a consumer started treatment with Simvastatin (dosage: NA). The following drugs/medications were being taken at the same time:
  • Ibuprofen
When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Lymphatic Disorder
  • Myalgia
  • Mass
  • Renal Failure
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Renal Failure, may become evident only after a product is in use by the general population.
Enterocolitis, Disease Progression, Sepsis, Pancytopenia, Renal Failure

This is a Simvastatin side effect report of a 77-year-old patient (weight: NA) from GERMANY. The patient developed the following symptoms/conditions: NA and was treated with Simvastatin (dosage: NA) starting Jan 20, 2011. Concurrently used drugs:
  • Amlodipine
  • Torsemide
  • Bisoprolol
  • Phenprocoumon
  • Metoclopramide
  • Prednisolone
  • Dekristol
  • Cabazitaxel
Soon after that, the consumer experienced the following of symptoms:
  • Enterocolitis
  • Disease Progression
  • Sepsis
  • Pancytopenia
  • Renal Failure
The patient was hospitalized. This opens a possibility that Simvastatin could cause Renal Failure and that some patients may be more susceptible.
Renal Failure

This Renal Failure side effect was reported by a physician from NETHERLANDS on Dec 06, 2011. A patient from NETHERLANDS , weighting 138.9 lb, was treated with Simvastatin. Patient felt the following Simvastatin side effects: renal failure. Simvastatin dosage: 40 Mg, Unk.
Multiple prescriptions taken:
  • Amlodipine (10 Mg, Unk)
  • Rasilez (300 Mg, Daily)
  • Tolbutamide (1000 Mg, Unk)
  • Metformin Hcl (500 Mg, Unk)
These side effects may potentially be related to Simvastatin.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Simvastatin Renal Failure Causes and Reviews


Healthy kidneys clean your blood by removing excess fluid, minerals, and wastes. They also make hormones that keep your bones strong and your blood healthy. But if the kidneys are damaged, they don't work properly. Harmful wastes can build up in your body. Your blood pressure may rise. Your body may retain excess fluid and not make enough red blood cells. This is called kidney failure.

If your kidneys fail, you need treatment to replace the work they normally do. The treatment options are dialysis or a kidney transplant. Each treatment has benefits and drawbacks. No matter which treatment you choose, you'll need to make some changes in your life, including how you eat and plan your activities. But with the help of health care providers, family, and friends, most people with kidney failure can lead full and active lives.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


Simvastatin Renal Failure Reviews

Wed, 29 Sep 2010

I've been on a Simvastatin for 6 months. I broke out in a mysterious rash about a few weeks after I began it. I've had a rash ever since. 2 dermatologist and 1 allergist later, it is the opinion of 1 dermatologist and the allergist that my rash is resulting from the Simvastatin. My heart dr. has never seen anyone get a rash from a Simvastatin, but he is going to work with me. He wants me to be off of everything I take (vitamins also) for 6 weeks. If the rash disappears, we will begin to introduce each pill 1 week at a time. I itch everywhere. The rash is terrible. My dermatologist has me on Doxepin at night, an antihistimine in the day, and cortizone mousse. I still itch. I can't seem to find others that have experienced a rash from a Simvastatin. Please reply if you can sympathize.

Sat, 20 Feb 2010

I was recently diagnosed with high cholesterol level so started taking Simvastatin a week ago. Two weeks befroe that, my podiatrist prescribed diclofenac sodium for my plantar fasciitis for a month. Are these two drugs conter-indicated???? PLus I am experiencing diarrhea with rectal pain and not sure which is the cause.

Fri, 05 Nov 2010

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed to go for my Appt. The rash totally subsided. I call it off the Appt. I noticed 3 days ago the rash started again, it is itch but I try not to scratch. I want to see if the rash will takes three wk to subside. I will let you know.

Fri, 15 Jan 2010

Has anyone taking this medication after a year,expierenced headaches?

Wed, 04 May 2011

Please reply me. Thanks.,

Wed, 24 Nov 2010

I have been in Zorcor for a good 6 years with no problems (40mg). I did not have any problems until recently. I now have a number of strange complaintes. I thought it may just be part of getting older. I am having joint and muscle pain and extreme headaches that absolutely debiliatate
me. I have a rash and my throat swells at times.Until reading some of your comments, I never suspected it could be from the same med. The swellinng in the throat was the final straw. I am officially off the med. as of today, with an immediate doctor visit in the works.

Thu, 24 Feb 2011

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niacin is known to create rash in many people along with other side effects that are similar to Zocor. If you are taking niacine as well as Zocor I believe the combination may be the cause as I have tried stopping either and the rash dimenishes, ythough does not disappear. The reduction of fats in your blood may just be giving you abnormally dry skin resulting in the rash as it seems ceaseing either pill reduces my rash to the area around a very small mole.

Tue, 06 Apr 2010

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Simvastatin Side Effects

Rhabdomyolysis (1168)
Myalgia (1039)
Renal Failure Acute (504)
Fatigue (491)
Blood Creatine Phosphokinase Increased (489)
Pain In Extremity (449)
Muscular Weakness (445)
Asthenia (394)
Arthralgia (375)
Muscle Spasms (346)
Pain (328)
Dyspnoea (311)
Dizziness (304)
Nausea (281)
Fall (261)
Diarrhoea (257)
Gait Disturbance (243)
Alanine Aminotransferase Increased (241)
Headache (240)
Myositis (238)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Paraesthesia (126)
Hypoaesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Pruritus (107)
Cough (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Mobility Decreased (98)
Abasia (98)

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