Simvastatin Rhabdomyolysis Side Effect Reports


The following Simvastatin Rhabdomyolysis side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Rhabdomyolysis, can occur, and what you can do about them.

A side effect could appear soon after you start Simvastatin or it might take time to develop.


Rhabdomyolysis, Dyspnoea

This Rhabdomyolysis side effect was reported by a pharmacist from COUNTRY NOT SPECIFIED. A 65-year-old patient (weight:NA) experienced the following symptoms/conditions: blood cholesterol increased,antifungal prophylaxis. The patient was prescribed Simvastatin 40 Mg (dosage: NA), which was started on NS. Concurrently used drugs:
  • Voriconazole
  • Metoprolol Succinate
  • Tacrolimus
  • Valacyclovir Tablets
  • Metformin
  • Atovaquone
  • Aspirin
  • Folic Acid
When starting to take Simvastatin 40 Mg the consumer reported the following symptoms:
  • Rhabdomyolysis
  • Dyspnoea
The patient was hospitalized. These side effects may potentially be related to Simvastatin 40 Mg.
Rhabdomyolysis

This Rhabdomyolysis Simvastatin side effect was reported by a pharmacist from US on Feb 07, 2014. A male , 60 years of age, weighting 239.4 lb, was diagnosed with and was treated with Simvastatin. The patient presented the following health conditions:
  • Rhabdomyolysis
. Simvastatin dosage: NA. Additional drugs used at the same time: NA. The patient was hospitalized.
Rhabdomyolysis

This is a Simvastatin side effect report of a 50-year-old patient (weight:NA) from SG, suffering from the following symptoms/conditions: hyperlipidaemia, who was treated with Simvastatin (dosage:Daily, start time: NS), combined with:
  • Amlodipine (Daily)
, and developed a serious reaction and a Rhabdomyolysis side effect. The patient presented with:
  • Rhabdomyolysis
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin treatment in patients suffering from hyperlipidaemia, resulting in Rhabdomyolysis.
Rhabdomyolysis, Neuralgia

A 66-year-old patient (weight: NA) from US with the following symptoms: NA started Simvastatin (simvastatin) treatment (dosage: NA) on Oct 28, 2013. Soon after starting Simvastatin (simvastatin) treatment, the consumer experienced several side effects, including:
  • Rhabdomyolysis
  • Neuralgia
. Concurrently used drugs:
  • Lopid (gemfibrozil) (120 Mg (60 Mg 2 In 1 D))
  • Victoza (liraglutide)
  • Finasteride (finasteride)
  • Terazosin Hydrochloride (terazosin Hydrocholoride)
  • Gabapentin (gabapentin)
  • Effient (prasugrel Hydrochloride)
  • Maxzide (dyazide)
  • Metformin Hydrochloride (metformin Hydrochloride)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Simvastatin (simvastatin) side effects, such as Rhabdomyolysis.
Rhabdomyolysis, Alanine Aminotransferase Increased, Haemoglobin Decreased

A female patient from NO was prescribed and started Simvastatin (simvastatin) on Jan 02, 2014. Patient felt the following Simvastatin side effects: rhabdomyolysis, alanine aminotransferase increased, haemoglobin decreased Additional patient health information: Female , 69 years of age, The consumer reported the following symptoms: was diagnosed with and. Simvastatin (simvastatin) dosage: NA. Concurrently used drugs:
  • Afinitor (everloimus)
  • Aromasin (exemestane)
  • Spriix (spironolactone)
  • Calcigran Forte (lekovit Ca)
  • Xgeva (denosumab)
  • Parafinemulsjon Naf (paraffin)
  • Paracet (paracetamol)
  • Centyl Med Kalium (salures-k)
The patient was hospitalized.
Renal Failure Acute, Rhabdomyolysis

This report suggests a potential Simvastatin Rhabdomyolysis side effect(s) that can have serious consequences. A 56-year-old patient from US (weight:NA) was diagnosed with the following health condition(s): hyperlipidaemia and used Simvastatin (dosage: NA) starting Aug 29, 2008. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Renal Failure Acute
  • Rhabdomyolysis
Drugs used concurrently:NA. The patient was hospitalized. Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rhabdomyolysis, may still occur.
Renal Failure Acute, Sepsis, Rhabdomyolysis

An adverse event was reported by a consumer or non-health professional on Dec 16, 2013 by a male taking Simvastatin (dosage: 40 Mg, Qd) was diagnosed with and. Location: GB , 87 years of age, weighting 149.9 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: renal failure acute, sepsis, rhabdomyolysis. Additional medications/treatments: The patient was hospitalized.
Blood Creatine Phosphokinase Increased, Transaminases Increased, Rhabdomyolysis

This Rhabdomyolysis problem was reported by a pharmacist from US. A 50-year-old patient (weight: NA) was diagnosed with the following medical condition(s): hiv infection.On Jul 01, 2005 a consumer started treatment with Simvastatin (dosage: NA). The following drugs/medications were being taken at the same time:
  • Zidovudine
When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Blood Creatine Phosphokinase Increased
  • Transaminases Increased
  • Rhabdomyolysis
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Rhabdomyolysis, may become evident only after a product is in use by the general population.
Rhabdomyolysis, Renal Failure Acute

This is a Simvastatin side effect report of a 58-year-old female patient (weight: NA) from AU. The patient developed the following symptoms/conditions: NA and was treated with Simvastatin (dosage: 80 Milligram) starting NS. Concurrently used drugs:
  • Gemfibrozil (600 Milligram)
Soon after that, the consumer experienced the following of symptoms:
  • Rhabdomyolysis
  • Renal Failure Acute
This opens a possibility that Simvastatin could cause Rhabdomyolysis and that some female patients may be more susceptible.
C-reactive Protein Increased, Myositis, Rhabdomyolysis, Muscular Weakness, Blood Creatine Phosphokinase Increased, Diabetes Mellitus, Blood Glucose Increased, Atrial Fibrillation, Oedema Peripheral

This Rhabdomyolysis side effect was reported by a consumer or non-health professional from CH on Nov 26, 2013. A female patient from CH , weighting 140.4 lb, was treated with Simvastatin. Directly after treatment started, patient experienced the unwanted or unexpected Simvastatin side effects: c-reactive protein increased, myositis, rhabdomyolysis, muscular weakness, blood creatine phosphokinase increased, diabetes mellitus, blood glucose increased, atrial fibrillation, oedema peripheral. Simvastatin dosage: Unk.
Associated medications used:
  • Exemestane (25 Mg, Qd)
  • Glyburide (Unk)
  • Afinitor (10 Mg, Qd)
  • L-thyroxin (Unk)
  • Beloc Zok Mite
  • Oxycodone (Unk)
  • Lasix (furosemide) (Unk)
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Myalgia, Rhabdomyolysis

This Rhabdomyolysis side effect was reported by a pharmacist from US. A 66-year-old patient (weight:NA) experienced the following symptoms/conditions: coronary artery disease. The patient was prescribed Simvastatin (dosage: 20 Mg, At Bedtime, Po), which was started on Jan 23, 2013. Concurrently used drugs: NA. When starting to take Simvastatin the consumer reported the following symptoms:
  • Myalgia
  • Rhabdomyolysis
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
Paraesthesia, Palpitations, Presyncope, Rhabdomyolysis, Vision Blurred

This Rhabdomyolysis Simvastatin side effect was reported by a physician from IT on Jan 22, 2014. A Female , 62 years of age, was diagnosed with and was treated with Simvastatin. The patient presented the following health conditions:
  • Paraesthesia
  • Palpitations
  • Presyncope
  • Rhabdomyolysis
  • Vision Blurred
. Simvastatin dosage: NA. Additional drugs used at the same time:
  • Plaunazide
  • Bisoprolol Hemifumarate
Formication, Palpitations, Presyncope, Rhabdomyolysis, Vision Blurred

This is a Simvastatin (simvastatin) side effect report of a 62-year-old female patient (weight:NA) from IT, suffering from the following symptoms/conditions: hypercholesterolaemia, who was treated with Simvastatin (simvastatin) (dosage:20mg (20mg, 1 In 1d) Oral, start time: Sep 28, 2013), combined with:
  • Bisoprolol (bisoprolol)
  • Plaunaziide (benicar Hct)
, and developed a serious reaction and a Rhabdomyolysis side effect. The patient presented with:
  • Formication
  • Palpitations
  • Presyncope
  • Rhabdomyolysis
  • Vision Blurred
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Simvastatin (simvastatin) treatment in female patients suffering from hypercholesterolaemia, resulting in Rhabdomyolysis.
Hypotension, Nausea, Vomiting, Diarrhoea, Metabolic Acidosis, Rhabdomyolysis, Renal Tubular Necrosis, Renal Failure, Lung Infiltration

A 24-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED with the following symptoms: NA started Simvastatin treatment (dosage: NA) on NS. Soon after starting Simvastatin treatment, the consumer experienced several side effects, including:
  • Hypotension
  • Nausea
  • Vomiting
  • Diarrhoea
  • Metabolic Acidosis
  • Rhabdomyolysis
  • Renal Tubular Necrosis
  • Renal Failure
  • Lung Infiltration
. Concurrently used drugs:
  • Amlodipine Besylate (400 To 600 Mg)
  • Trazodone
  • Sertraline
This finding indicates that some patients can be more vulnerable to developing Simvastatin side effects, such as Rhabdomyolysis.
Paraesthesia, Palpitations, Syncope, Rhabdomyolysis, Vision Blurred

A female patient from IT was prescribed and started Simvastatin on Jan 28, 2014. After Simvastatin was administered, patient encountered several Simvastatin side effects: paraesthesia, palpitations, syncope, rhabdomyolysis, vision blurred Additional patient health information: Female , 62 years of age, The consumer reported the following symptoms: was diagnosed with and. Simvastatin dosage: 20 Mg Daily. Concurrently used drugs:
  • Plaunazide (32.5 Mg)
  • Bisoprolol Hemifumarate (1.25 Mg)
Syncope, Rhabdomyolysis

This report suggests a potential Simvastatin Rhabdomyolysis side effect(s) that can have serious consequences. A 63-year-old female patient from IT (weight:NA) was diagnosed with the following health condition(s): hypercholesterolaemia,hypertension and used Simvastatin (dosage: 20 Mg, Qd) starting Sep 28, 2013. Soon after starting Simvastatin the patient began experiencing various side effects, including:
  • Syncope
  • Rhabdomyolysis
Drugs used concurrently:
  • Hydrochlorothiazide W/olmesartan (32.5 Mg,)
  • Bisoprolol (1.25 Mg)
Although Simvastatin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rhabdomyolysis, may still occur.
Acute Myocardial Infarction, Rhabdomyolysis, Renal Failure Acute, Acute Coronary Syndrome

An adverse event was reported by a consumer or non-health professional on Oct 25, 2013 by a male taking Simvastatin (dosage: NA) . Location: COUNTRY NOT SPECIFIED , 81 years of age, patient began experiencing various side effects, including: Patient felt the following Simvastatin side effects: acute myocardial infarction, rhabdomyolysis, renal failure acute, acute coronary syndrome. Additional medications/treatments:
Multiple prescriptions taken:
  • Gemfibrozil
  • Aspirin
  • Clopidogrel
  • Isosorbide Dinitrate
  • Furosemide
  • Metoprolol Tartrate
  • Omeprazole
Sepsis, Renal Failure Acute, Rhabdomyolysis

This Rhabdomyolysis problem was reported by a consumer or non-health professional from GB. A 87-year-old patient (weight: NA) was diagnosed with the following medical condition(s): hypercholesterolaemia.On Dec 20, 2012 a consumer started treatment with Simvastatin (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Simvastatin, the patient experienced the following unwanted symptoms /side effects:
  • Sepsis
  • Renal Failure Acute
  • Rhabdomyolysis
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Rhabdomyolysis, may become evident only after a product is in use by the general population.
Rhabdomyolysis, Renal Failure Acute

This is a Simvastatin (simvastatin) side effect report of a 58-year-old female patient (weight: NA) from AU. The patient developed the following symptoms/conditions: NA and was treated with Simvastatin (simvastatin) (dosage: NA) starting NS. Concurrently used drugs:
  • Gemfibrozil (gemfibrozil)
Soon after that, the consumer experienced the following of symptoms:
  • Rhabdomyolysis
  • Renal Failure Acute
This opens a possibility that Simvastatin (simvastatin) could cause Rhabdomyolysis and that some female patients may be more susceptible.
Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Swelling Face, Contusion, Mobility Decreased, Fall

This Rhabdomyolysis side effect was reported by a health professional from GB on Oct 09, 2013. A female patient from GB , 94 years of age, was diagnosed with and was treated with Simvastatin. Patient felt the following Simvastatin side effects: rhabdomyolysis, blood creatine phosphokinase increased, swelling face, contusion, mobility decreased, fall. Simvastatin dosage: NA.
Multiple prescriptions taken:
  • Slozem
  • Allopurinol
  • Aspirin
  • Ferrous Sulphate
  • Furosemide
  • Mirtazapine
  • Omeprazole
  • Ramipril
The patient was hospitalized. These side effects may potentially be related to Simvastatin.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Simvastatin Rhabdomyolysis Causes and Reviews


Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that can affect muscles. Muscle disorders can cause weakness, pain or even paralysis.

Causes of muscle disorders include

  • Injury or overuse, such as sprains or strains, cramps or tendinitis
  • A genetic disorder, such as muscular dystrophy
  • Some cancers
  • Inflammation, such as myositis
  • Diseases of nerves that affect muscles
  • Infections
  • Certain medicines

Sometimes the cause is not known.


Simvastatin Rhabdomyolysis Reviews

Wed, 29 Sep 2010

I've been on a Simvastatin for 6 months. I broke out in a mysterious rash about a few weeks after I began it. I've had a rash ever since. 2 dermatologist and 1 allergist later, it is the opinion of 1 dermatologist and the allergist that my rash is resulting from the Simvastatin. My heart dr. has never seen anyone get a rash from a Simvastatin, but he is going to work with me. He wants me to be off of everything I take (vitamins also) for 6 weeks. If the rash disappears, we will begin to introduce each pill 1 week at a time. I itch everywhere. The rash is terrible. My dermatologist has me on Doxepin at night, an antihistimine in the day, and cortizone mousse. I still itch. I can't seem to find others that have experienced a rash from a Simvastatin. Please reply if you can sympathize.

Sat, 20 Feb 2010

I was recently diagnosed with high cholesterol level so started taking Simvastatin a week ago. Two weeks befroe that, my podiatrist prescribed diclofenac sodium for my plantar fasciitis for a month. Are these two drugs conter-indicated???? PLus I am experiencing diarrhea with rectal pain and not sure which is the cause.

Fri, 05 Nov 2010

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed to go for my Appt. The rash totally subsided. I call it off the Appt. I noticed 3 days ago the rash started again, it is itch but I try not to scratch. I want to see if the rash will takes three wk to subside. I will let you know.

Fri, 15 Jan 2010

Has anyone taking this medication after a year,expierenced headaches?

Wed, 04 May 2011

Please reply me. Thanks.,

Wed, 24 Nov 2010

I have been in Zorcor for a good 6 years with no problems (40mg). I did not have any problems until recently. I now have a number of strange complaintes. I thought it may just be part of getting older. I am having joint and muscle pain and extreme headaches that absolutely debiliatate
me. I have a rash and my throat swells at times.Until reading some of your comments, I never suspected it could be from the same med. The swellinng in the throat was the final straw. I am officially off the med. as of today, with an immediate doctor visit in the works.

Thu, 24 Feb 2011

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niacin is known to create rash in many people along with other side effects that are similar to Zocor. If you are taking niacine as well as Zocor I believe the combination may be the cause as I have tried stopping either and the rash dimenishes, ythough does not disappear. The reduction of fats in your blood may just be giving you abnormally dry skin resulting in the rash as it seems ceaseing either pill reduces my rash to the area around a very small mole.

Tue, 06 Apr 2010

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Simvastatin Side Effects

Rhabdomyolysis (1169)
Myalgia (1039)
Renal Failure Acute (504)
Fatigue (491)
Blood Creatine Phosphokinase Increased (489)
Pain In Extremity (449)
Muscular Weakness (445)
Asthenia (394)
Arthralgia (375)
Muscle Spasms (346)
Pain (328)
Dyspnoea (311)
Dizziness (304)
Nausea (281)
Fall (261)
Diarrhoea (257)
Gait Disturbance (243)
Alanine Aminotransferase Increased (241)
Headache (240)
Myositis (238)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Paraesthesia (126)
Hypoaesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Pruritus (107)
Cough (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Mobility Decreased (98)
Abasia (98)

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