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Spironolactone Anaemia Side Effects

Spironolactone Anaemia Side Effect Reports


The following Spironolactone Anaemia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Anaemia, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Anaemia, Renal Failure

This Anaemia side effect was reported by a health professional from FR. A 56-year-old female patient (weight:NA) experienced the following symptoms/conditions: cirrhosis alcoholic. The patient was prescribed Spironolactone (dosage: 75 Mg, 3x/day), which was started on 201304. Concurrently used drugs:
  • Lasilix (80 Mg, Daily)
  • Inexium (40 Mg, 1x/day)
  • Avlocardyl (40 Mg, 2x/day)
  • Vitamin B1 And B6
When starting to take Spironolactone the consumer reported the following symptoms:
  • Anaemia
  • Renal Failure
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Gastrointestinal Haemorrhage, Anaemia, Epistaxis

This Anaemia Spironolactone side effect was reported by a consumer or non-health professional from US on Feb 11, 2014. A Female , 67 years of age, weighting 150.0 lb, was treated with Spironolactone. The patient presented the following health conditions:
  • Gastrointestinal Haemorrhage
  • Anaemia
  • Epistaxis
. Spironolactone dosage: 25 Mg. Additional drugs used at the same time:
  • Pravastatin (20 Mg)
  • Ferrous Sulfate (975 Mg)
  • Protonix (80 Mg)
  • Senna
  • Vitamin C (1000 Mg)
  • Pradaxa (300 Mg)
  • Aspirin (81 Mg)
  • Vitamin D (1000 U)
The patient was hospitalized.
Hyperkalaemia, Anaemia, Renal Failure

This is a Spironolactone side effect report of a 71-year-old patient (weight:NA) from DE, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Anaemia side effect. The patient presented with:
  • Hyperkalaemia
  • Anaemia
  • Renal Failure
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in patients suffering from NA, resulting in Anaemia.

Cardiac Failure, Pneumonitis, Asthenia, Productive Cough, Pyrexia, Oedema, Anaemia, Dyspnoea Exertional

A 59-year-old patient (weight: NA) from ES with the following symptoms: NA started Spironolactone treatment (dosage: Daily Dose 25 Mg) on Jun 26, 2012. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Cardiac Failure
  • Pneumonitis
  • Asthenia
  • Productive Cough
  • Pyrexia
  • Oedema
  • Anaemia
  • Dyspnoea Exertional
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Anaemia.
Lactic Acidosis, Hyperkalaemia, Cardio-respiratory Arrest, Atrioventricular Block Complete, Hypoglycaemia, Anaemia, International Normalised Ratio Increased, Activated Partial Thromboplastin Time Prolonged, Renal Failure Acute

A patient from AU was prescribed and started Spironolactone on Feb 27, 2013. Patient felt the following Spironolactone side effects: lactic acidosis, hyperkalaemia, cardio-respiratory arrest, atrioventricular block complete, hypoglycaemia, anaemia, international normalised ratio increased, activated partial thromboplastin time prolonged, renal failure acute Additional patient health information: male , 65 years of age, The consumer reported the following symptoms: . Spironolactone dosage: NA. Concurrently used drugs:
  • Metformin Hydrochloride
  • Trandolapril
The patient was hospitalized.
Anhedonia, Respiratory Tract Congestion, Blood Pressure Increased, Heart Rate Irregular, Insomnia, Anaemia, Gastritis Erosive, Back Pain, Abdominal Discomfort

This report suggests a potential Spironolactone Anaemia side effect(s) that can have serious consequences. A 73-year-old patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: NA) starting Jan 01, 1997. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Anhedonia
  • Respiratory Tract Congestion
  • Blood Pressure Increased
  • Heart Rate Irregular
  • Insomnia
  • Anaemia
  • Gastritis Erosive
  • Back Pain
  • Abdominal Discomfort
Drugs used concurrently:
  • Lisinopril
  • Coumadin
  • Spiriva
  • Cardizem
  • Ciprofloxacin Hcl
  • Urocit-k
  • Meclizine
  • Nitroglycerin
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaemia, may still occur.
Stomatitis, Off Label Use, Anaemia, Mucosal Inflammation, Aphagia, Thermal Burn, Skin Ulcer

An adverse event was reported by a health professional on Apr 13, 2012 by a Female taking Spironolactone (dosage: NA) . Location: UNITED STATES , weighting 97.00 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: stomatitis, off label use, anaemia, mucosal inflammation, aphagia, thermal burn, skin ulcer. Additional medications/treatments:
Associated medications used:
  • Morphine
  • Cyanocobalamin
  • Tarceva
  • Pyridoxine Hcl
  • Avastin (Unk)
  • Prochlorperazine Maleate
  • Miracle Mouthwash (Unk)
  • Diphenhydramine Hydrochloride (Unk)
Dyspnoea, Anaemia, Heart Rate Increased, Depression, Pruritus

This Anaemia problem was reported by a consumer or non-health professional from UNITED STATES. A 39-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Aug 13, 2011 a consumer started treatment with Spironolactone (dosage: NA). The following drugs/medications were being taken at the same time:
  • Ribavirin
  • Incivek (2250 Mg (750 Mg, 1 In 8 Hr), Oral)
  • Pegasys
  • Lactulose
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Dyspnoea
  • Anaemia
  • Heart Rate Increased
  • Depression
  • Pruritus
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Anaemia, may become evident only after a product is in use by the general population.
Rectal Haemorrhage, Hypersensitivity, Asthenia, Oedema Peripheral, Malaise, Dyspnoea, Anaemia, Polyp, Joint Swelling

This is a Spironolactone side effect report of a 76-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: swelling and was treated with Spironolactone (dosage: NA) starting Jan 01, 2010. Concurrently used drugs:
  • Metoprolol Succinate
  • Brovana
  • Tracleer
  • Furosemide
Soon after that, the consumer experienced the following of symptoms:
  • Rectal Haemorrhage
  • Hypersensitivity
  • Asthenia
  • Oedema Peripheral
  • Malaise
  • Dyspnoea
  • Anaemia
  • Polyp
  • Joint Swelling
The patient was hospitalized. This opens a possibility that Spironolactone could cause Anaemia and that some female patients may be more susceptible.
Anaemia, Haemoglobin Decreased, Aplastic Anaemia, Bone Marrow Failure, Immunosuppression

This Anaemia side effect was reported by a consumer or non-health professional from NETHERLANDS on Nov 17, 2011. A patient from NETHERLANDS , weighting 174.2 lb, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: anaemia, haemoglobin decreased, aplastic anaemia, bone marrow failure, immunosuppression. Spironolactone dosage: 125 Mg, Unk.
Associated medications used:
  • Inspra (25 Mg, Qd)
  • Carvedilol (12.5 Mg, Bid)
  • Sintrom
  • Amiodarone Hcl (50 Mg, Qd)
  • Diovan (80 Mg, Bid)
  • Furosemide (20 Mg, Bid)
  • Ramipril (5 Mg, Bid)
  • Lipitor (10 Mg, Qd)
These side effects may potentially be related to Spironolactone.
Upper Gastrointestinal Haemorrhage, Gastric Ulcer, Anaemia

This Anaemia side effect was reported by a physician from UNITED STATES. A 72-year-old patient (weight:NA) experienced the following symptoms/conditions: hepatic cirrhosis,hepatic neoplasm malignant,diabetes mellitus. The patient was prescribed Spironolactone (dosage: 100 Mg, Qd), which was started on Jan 01, 2007. Concurrently used drugs:
  • Sorafenib (raf Kinase Inhibitor) (400 Mg, Bid)
  • Metformin Hcl (500 Mg, Tid)
  • Linifanib
  • Silybum Marianum (250 Mg, Bid)
  • Propranolol (20 Mg, Bid)
  • Furosemide (40 Mg, Qod)
When starting to take Spironolactone the consumer reported the following symptoms:
  • Upper Gastrointestinal Haemorrhage
  • Gastric Ulcer
  • Anaemia
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Acute Right Ventricular Failure, Anaemia, Weight Increased, Urticaria, Arthralgia, Pharyngeal Oedema, Pulmonary Hypertension, Venous Thrombosis

This Anaemia Spironolactone side effect was reported by a physician from UNITED STATES on Jun 23, 2011. A Female , weighting 179.9 lb, was treated with Spironolactone. The patient presented the following health conditions:
  • Acute Right Ventricular Failure
  • Anaemia
  • Weight Increased
  • Urticaria
  • Arthralgia
  • Pharyngeal Oedema
  • Pulmonary Hypertension
  • Venous Thrombosis
. Spironolactone dosage: NA. Additional drugs used at the same time:
  • Actemra (Form: Infusion)
  • Coumadin
  • Methotrexate Sodium (Dose: 25mg/ml)
  • Prednisone
  • Actemra
  • Actemra
  • Tylenol-500
  • Ibuprofen
The patient was hospitalized.
Acute Right Ventricular Failure, Anaemia, Arthralgia, Mesenteric Artery Thrombosis, Ventricular Tachycardia, Urticaria, Weight Increased, Venous Thrombosis, Pulmonary Hypertension

This is a Spironolactone side effect report of a female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:NA, start time: Jan 04, 2011), combined with:
  • Coumadin
  • Solu-medrol
  • Actemra
  • Actemra
  • Percocet
  • Benadryl
  • Actemra (Other Indication: Rheumatoid Arthritis, Dose: ^280^)
  • Ibuprofen
, and developed a serious reaction and a Anaemia side effect. The patient presented with:
  • Acute Right Ventricular Failure
  • Anaemia
  • Arthralgia
  • Mesenteric Artery Thrombosis
  • Ventricular Tachycardia
  • Urticaria
  • Weight Increased
  • Venous Thrombosis
  • Pulmonary Hypertension
which developed after the beginning of treatment. The patient was hospitalized and became disabled. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from NA, resulting in Anaemia.
Erysipelas, Leukopenia, Anaemia, Bone Marrow Failure, Agranulocytosis

A 87-year-old female patient (weight: NA) from FRANCE with the following symptoms: essential hypertension,pain started Spironolactone treatment (dosage: 25 Mg, Qd) on Jan 01, 2010. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Erysipelas
  • Leukopenia
  • Anaemia
  • Bone Marrow Failure
  • Agranulocytosis
. Concurrently used drugs:
  • Novalgin (Unk)
  • Beloc Zok (50 Mg, Qd)
  • Pantozol (20 Mg, Qd)
  • Aspirin (100 Mg, Qd)
  • Altace (5 Mg, Qd)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Anaemia.
Respiratory Failure, Anaemia, Multi-organ Failure, Sepsis, Hepatic Failure, Renal Failure, Hypotension, Haemorrhage

A female patient from UNITED STATES was prescribed and started Spironolactone on Feb 23, 2011. After Spironolactone was administered, patient encountered several Spironolactone side effects: respiratory failure, anaemia, multi-organ failure, sepsis, hepatic failure, renal failure, hypotension, haemorrhage Additional patient health information: Female , weighting 137.0 lb, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: (oral). Concurrently used drugs: NA.
Anaemia, Hyperkalaemia, Metabolic Acidosis, Paralysis, Renal Failure

This report suggests a potential Spironolactone Anaemia side effect(s) that can have serious consequences. A 72-year-old patient from BRAZIL (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: NA) starting NS. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Anaemia
  • Hyperkalaemia
  • Metabolic Acidosis
  • Paralysis
  • Renal Failure
Drugs used concurrently:
  • Amiodarone (Unk)
  • Isosorbide Mononitrate (Unk)
  • Furosemide (Unk)
  • Losartan (Unk)
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaemia, may still occur.
Anaemia, Hyperkalaemia, Hyponatraemia

An adverse event was reported by a pharmacist on Mar 03, 2009 by a Female taking Spironolactone (dosage: 25 Mg/daily, Oral) was diagnosed with and. Location: GERMANY , 92 years of age, weighting 187.4 lb, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: anaemia, hyperkalaemia, hyponatraemia. Additional medications/treatments:
Multiple prescriptions taken:
  • Furosemide (furosemide) Tablet (40 Mg/daily, Oral)
  • Enoxaparin Sodium (20 Mg/daily, Subcutaneous)
  • Pantoprazole Sodium
  • Norvasc
  • Movicol (macrogol, Potassium Chloride, Sodium Bicarcbonate, Sodium Chl
  • Eunerpan (melperone Hydrochloride)
  • Atacand
  • Aricept
The patient was hospitalized.
Anaemia, Colitis Ulcerative, Diarrhoea, Gastritis Atrophic, Rectal Haemorrhage

This Anaemia problem was reported by a health professional from FRANCE. A 70-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jan 01, 2001 a consumer started treatment with Spironolactone (dosage: NA). The following drugs/medications were being taken at the same time:
  • Sotalol Hydrochloride
  • Aspegic 1000
  • Plavix
  • Amlor
  • Elisor (40 Mg)
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Anaemia
  • Colitis Ulcerative
  • Diarrhoea
  • Gastritis Atrophic
  • Rectal Haemorrhage
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Anaemia, may become evident only after a product is in use by the general population.
Abdominal Pain, Anaemia, Ascites, Constipation, Depression, Disease Progression, Fatigue, Hyponatraemia, Oedema Peripheral

This is a Spironolactone side effect report of a 41-year-old patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: Qd; Po) starting Apr 01, 2004. Concurrently used drugs:
  • Su-011, 248 (sunitinib Malate) (no Pref. Name) (25 Mg; Bid; Po)
  • Furosemide (Qd, Po)
  • Warfarin Sodium
  • Lorazepam
Soon after that, the consumer experienced the following of symptoms:
  • Abdominal Pain
  • Anaemia
  • Ascites
  • Constipation
  • Depression
  • Disease Progression
  • Fatigue
  • Hyponatraemia
  • Oedema Peripheral
This opens a possibility that Spironolactone could cause Anaemia and that some patients may be more susceptible.
Anaemia, Colitis Ulcerative, Diarrhoea, Gastritis Atrophic, Rectal Haemorrhage

This Anaemia side effect was reported by a health professional from FRANCE on Dec 05, 2006. A patient from FRANCE , 70 years of age, was treated with Spironolactone. Patient felt the following Spironolactone side effects: anaemia, colitis ulcerative, diarrhoea, gastritis atrophic, rectal haemorrhage. Spironolactone dosage: NA.
Multiple prescriptions taken:
  • Sotalol Hydrochloride
  • Aspegic 1000
  • Plavix
  • Amlor
  • Pravastatin (40 Mg)
The patient was hospitalized. These side effects may potentially be related to Spironolactone.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Anaemia Causes and Reviews


If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute


Spironolactone Anaemia Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
Blood Creatinine Increased (48)
Fatigue (46)
Hypotension (43)
Renal Failure (41)
Dizziness (40)
Pain (37)
Bradycardia (36)
Vomiting (33)
Hyponatraemia (33)
Oedema Peripheral (31)
Atrial Fibrillation (28)
Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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