Spironolactone Anxiety Side Effect Reports


The following Spironolactone Anxiety side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Anxiety, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.


Anxiety, Palpitations

This Anxiety side effect was reported by a physician from GB. A 39-year-old female patient (weight:NA) experienced the following symptoms/conditions: acne. The patient was prescribed Spironolactone (dosage: 100 Mg, Qd), which was started on 201305. Concurrently used drugs: NA. When starting to take Spironolactone the consumer reported the following symptoms:
  • Anxiety
  • Palpitations
These side effects may potentially be related to Spironolactone.
Anxiety, Palpitations, Off Label Use

This Anxiety Spironolactone side effect was reported by a health professional from GB on Feb 19, 2014. A Female , 39 years of age, was diagnosed with and was treated with Spironolactone. The patient presented the following health conditions:
  • Anxiety
  • Palpitations
  • Off Label Use
. Spironolactone dosage: 100 Milligram Daily;. Additional drugs used at the same time: NA.
Anxiety, Palpitations

This is a Spironolactone side effect report of a 39-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: acne, who was treated with Spironolactone (dosage:100 Mg, Once Daily, start time: 201305), combined with: NA., and developed a serious reaction and a Anxiety side effect. The patient presented with:
  • Anxiety
  • Palpitations
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from acne, resulting in Anxiety.
Emotional Distress, Flatulence, Dyspepsia, Injury, Cholecystectomy, Scar, Abdominal Distension, Diarrhoea, Anxiety

A 28-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Spironolactone treatment (dosage: Unk) on Jan 01, 2007. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Emotional Distress
  • Flatulence
  • Dyspepsia
  • Injury
  • Cholecystectomy
  • Scar
  • Abdominal Distension
  • Diarrhoea
  • Anxiety
. Concurrently used drugs:
  • Yaz (Unk)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Anxiety.
Complicated Migraine, Anxiety, Cerebrovascular Accident, Transient Ischaemic Attack, Injury, Pain, Anhedonia

A female patient from UNITED STATES was prescribed and started Spironolactone on Mar 23, 2012. Patient felt the following Spironolactone side effects: complicated migraine, anxiety, cerebrovascular accident, transient ischaemic attack, injury, pain, anhedonia Additional patient health information: Female , 21 years of age, The consumer reported the following symptoms: . Spironolactone dosage: 50 Mg, Qd. Concurrently used drugs:
  • Yaz (Unk)
The patient was hospitalized.
Cholecystectomy, Pain, Constipation, Diarrhoea, Anxiety, Injury, Dyspepsia, Abdominal Distension, Emotional Distress

This report suggests a potential Spironolactone Anxiety side effect(s) that can have serious consequences. A 28-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: Unk) starting Jan 01, 2007. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Cholecystectomy
  • Pain
  • Constipation
  • Diarrhoea
  • Anxiety
  • Injury
  • Dyspepsia
  • Abdominal Distension
  • Emotional Distress
Drugs used concurrently:
  • Yaz (Unk)
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anxiety, may still occur.
Anxiety, Depression, Pulmonary Embolism

An adverse event was reported by a consumer or non-health professional on Mar 14, 2012 by a Female taking Spironolactone (dosage: Unk) . Location: UNITED STATES , 38 years of age, weighting 178.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: anxiety, depression, pulmonary embolism. Additional medications/treatments:
Associated medications used:
  • Phentermine
  • Ibuprofen (800 Mg, Unk)
  • Yaz (Unk)
  • Ibuprofen (800 Mg, Unk)
  • Cephalexin (Unk)
  • Ibuprofen (800 Mg, Unk)
  • Apap W/ Codeine (1-2 Tablets Daily)
  • Metformin Hcl (Unk)
The patient was hospitalized.
Musculoskeletal Pain, Pain In Extremity, Painful Respiration, Anxiety, Hypoacusis, Decreased Appetite, Arthritis

This Anxiety problem was reported by a consumer or non-health professional from UNITED STATES. A 85-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): hypertension.On Apr 18, 2006 a consumer started treatment with Spironolactone (dosage: NA). The following drugs/medications were being taken at the same time:
  • Dyrenium (triamterene) 60 Mg Once Daily
  • Felodipine
  • Norpace (disopyramide Phosphate) 150 Mg 4 Times Daily, Lanoxin (digoxi
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Musculoskeletal Pain
  • Pain In Extremity
  • Painful Respiration
  • Anxiety
  • Hypoacusis
  • Decreased Appetite
  • Arthritis
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Anxiety, may become evident only after a product is in use by the general population.
Anxiety, Injury, Pain, Cholecystitis Chronic, Gallbladder Disorder, Abdominal Pain

This is a Spironolactone side effect report of a 26-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: NA) starting Jan 01, 1999. Concurrently used drugs:
  • Yasmin (Unk)
  • Drospirenone And Ethinyl Estradiol (Unk)
  • Ibuprofen (Unk)
  • Adoxa (Unk)
Soon after that, the consumer experienced the following of symptoms:
  • Anxiety
  • Injury
  • Pain
  • Cholecystitis Chronic
  • Gallbladder Disorder
  • Abdominal Pain
The patient was hospitalized. This opens a possibility that Spironolactone could cause Anxiety and that some female patients may be more susceptible.
Renal Injury, Anxiety, Renal Impairment, Emotional Distress, Multi-organ Failure, Renal Failure

This Anxiety side effect was reported by a consumer or non-health professional from UNITED STATES on Dec 14, 2011. A patient from UNITED STATES , 76 years of age, weighting 180.0 lb, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: renal injury, anxiety, renal impairment, emotional distress, multi-organ failure, renal failure. Spironolactone dosage: Unk.
Associated medications used:
  • Trasylol
  • Norvasc
  • Trasylol (200 Ml X 2, Unk)
  • Synthroid
These side effects may potentially be related to Spironolactone.
Emotional Distress, Chest Pain, Coeliac Disease, Abdominal Pain, Anxiety, Food Allergy, Cholecystitis Chronic, Gallbladder Disorder

This Anxiety side effect was reported by a health professional from UNITED STATES. A 23-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Spironolactone (dosage: 50 Mg, Unk), which was started on Jan 01, 2008. Concurrently used drugs:
  • Repliva
  • Levothyroxine Sodium (0.75 Mg, Unk)
  • Yaz
  • Yaz (Unk)
  • Yaz
  • Vitamin D (Unk)
When starting to take Spironolactone the consumer reported the following symptoms:
  • Emotional Distress
  • Chest Pain
  • Coeliac Disease
  • Abdominal Pain
  • Anxiety
  • Food Allergy
  • Cholecystitis Chronic
  • Gallbladder Disorder
These side effects may potentially be related to Spironolactone.
Pulmonary Embolism, Oedema Peripheral, Pain, Dyspnoea, Pain In Extremity, Deep Vein Thrombosis, Anxiety, Anhedonia

This Anxiety Spironolactone side effect was reported by a physician from UNITED STATES on Oct 19, 2011. A Female , 41 years of age, weighting 237.0 lb, was treated with Spironolactone. The patient presented the following health conditions:
  • Pulmonary Embolism
  • Oedema Peripheral
  • Pain
  • Dyspnoea
  • Pain In Extremity
  • Deep Vein Thrombosis
  • Anxiety
  • Anhedonia
. Spironolactone dosage: Unk. Additional drugs used at the same time:
  • Phentermine (Unk)
  • Tpn (Unk)
  • Motrin (Various Dates Since 1992)
  • Ibuprofen
  • Yaz
The patient was hospitalized.
Anger, Vomiting, Depression, Anxiety, Cholelithiasis, Disability, Gastrointestinal Pain, Gallbladder Cholesterolosis, Abdominal Pain

This is a Spironolactone side effect report of a 25-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: polycystic ovaries, who was treated with Spironolactone (dosage:100 Mg, Bid, start time: Apr 04, 2007), combined with:
  • Vitamin B-12
  • Ascorbic Acid (Unk)
  • Levaquin (500 Mg, Unk)
  • Phenergan Hcl (Unk)
  • Drospirenone And Ethinyl Estradiol
  • Biotin (Unk)
  • Allegra (Daily Dose 80 Mg)
  • Metformin Hcl (1000 Mg, Unk)
, and developed a serious reaction and a Anxiety side effect. The patient presented with:
  • Anger
  • Vomiting
  • Depression
  • Anxiety
  • Cholelithiasis
  • Disability
  • Gastrointestinal Pain
  • Gallbladder Cholesterolosis
  • Abdominal Pain
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from polycystic ovaries, resulting in Anxiety.
Abdominal Pain, Fear, Injury, Procedural Pain, Emotional Distress, Anxiety, Dyspepsia, Psychiatric Symptom, Gallbladder Disorder

A 40-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: acne,hypertension started Spironolactone treatment (dosage: Unk) on Jan 01, 2007. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Abdominal Pain
  • Fear
  • Injury
  • Procedural Pain
  • Emotional Distress
  • Anxiety
  • Dyspepsia
  • Psychiatric Symptom
  • Gallbladder Disorder
. Concurrently used drugs:
  • Bisoprolol Fumarate (Unk)
  • Yaz (Unk)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Anxiety.
Renal Injury, Stress, Anxiety, Renal Failure, Fear, Renal Impairment, Unevaluable Event, Anhedonia

A female patient from UNITED STATES was prescribed and started Spironolactone on Jun 06, 2009. After Spironolactone was administered, patient encountered several Spironolactone side effects: renal injury, stress, anxiety, renal failure, fear, renal impairment, unevaluable event, anhedonia Additional patient health information: Female , 69 years of age, weighting 185.2 lb, The consumer reported the following symptoms: . Spironolactone dosage: 25mg. Concurrently used drugs:
  • Cardizem (120mg Daily)
  • Coumadin (2.5mg-no Pill Sundays)
  • Captopril (Unk)
  • Coreg (0.25mg ? Tab Bid)
  • Trasylol (, Loading Dose Of 200ml, Then 50cc Per Hour Drip)
  • Insulin (Unk)
  • Acetylsalicylic Acid Srt
  • Trasylol (Initial (test) Dose Of 1 Ml)
Injury, Anxiety, Anhedonia, Cardiogenic Shock, Pain, Fear, Unevaluable Event, Renal Failure

This report suggests a potential Spironolactone Anxiety side effect(s) that can have serious consequences. A 30-year-old patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: 25 Mg Daily) starting Jul 15, 2007. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Injury
  • Anxiety
  • Anhedonia
  • Cardiogenic Shock
  • Pain
  • Fear
  • Unevaluable Event
  • Renal Failure
Drugs used concurrently:
  • Trasylol (Initial (test) Dose Of 1 Ml)
  • Altace
  • Heparin (Unk)
  • Cryoprecipitates (40)
  • Lasix (40 Mg Daily)
  • Coreg (3.125 Mg)
  • Protamine Sulfate (Unk)
  • Platelets (Unk)
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anxiety, may still occur.
Pulmonary Thrombosis, Pain, Cholelithiasis, Anxiety, Nausea, Pulmonary Embolism, Musculoskeletal Pain, Dyspnoea, Cholecystitis Chronic

An adverse event was reported by a consumer or non-health professional on Nov 24, 2010 by a Female taking Spironolactone (dosage: NA) . Location: UNITED STATES , 32 years of age, weighting 130.1 lb, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: pulmonary thrombosis, pain, cholelithiasis, anxiety, nausea, pulmonary embolism, musculoskeletal pain, dyspnoea, cholecystitis chronic. Additional medications/treatments:
Multiple prescriptions taken:
  • Bactrim
  • Naproxen (aleve)
  • Yasmin (Unk)
  • Benzaclin
  • Yaz (0.02 Mg Ethinyl Estradiol 3 Mg Drospirenone)
  • Plexion
  • Prilosec
  • Singulair
The patient was hospitalized.
Stress, Unevaluable Event, Pain, Anhedonia, Multi-organ Failure, Renal Impairment, Anxiety, Renal Injury, Mental Disorder

This Anxiety problem was reported by a consumer or non-health professional from UNITED STATES. A 76-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jan 21, 2005 a consumer started treatment with Spironolactone (dosage: Unk). The following drugs/medications were being taken at the same time:
  • Trasylol (200 Ml X 2, Unk)
  • Trasylol
  • Synthroid
  • Norvasc
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Stress
  • Unevaluable Event
  • Pain
  • Anhedonia
  • Multi-organ Failure
  • Renal Impairment
  • Anxiety
  • Renal Injury
  • Mental Disorder
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Anxiety, may become evident only after a product is in use by the general population.
Emotional Distress, Unevaluable Event, Pain, Fear, Renal Injury, Multi-organ Failure, Anxiety

This is a Spironolactone side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: 25 Mg/d, Unk) starting Feb 22, 2002. Concurrently used drugs:
  • Trasylol (100 Ml Followed By Maintenance Drip Of 25 Ml/hour)
  • Nitroglycerin (0.2 Mg/24hr, Unk)
  • Dobutamine Hcl (Unk)
  • Glucotrol (10 Mg, Bid)
  • Solu-medrol
  • Sufentanil Citrate (50 Mcg)
  • Aspirin (81 Mg/d, Unk)
  • Toprol-xl (100 Mg/d, Unk)
Soon after that, the consumer experienced the following of symptoms:
  • Emotional Distress
  • Unevaluable Event
  • Pain
  • Fear
  • Renal Injury
  • Multi-organ Failure
  • Anxiety
This opens a possibility that Spironolactone could cause Anxiety and that some female patients may be more susceptible.
Anxiety, Migraine With Aura

This Anxiety side effect was reported by a consumer or non-health professional from UNITED STATES on Dec 22, 2010. A female patient from UNITED STATES , weighting 240.0 lb, was diagnosed with and was treated with Spironolactone W/ Hydrochlorothiazide. Patient felt the following Spironolactone side effects: anxiety, migraine with aura. Spironolactone W/ Hydrochlorothiazide dosage: Unk.
Multiple prescriptions taken:
  • Pristiq (50 Mg, Daily)
These side effects may potentially be related to Spironolactone W/ Hydrochlorothiazide.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Anxiety Causes and Reviews


Fear and Anxiety are part of life. You may feel anxious before you take a test or walk down a dark street. This kind of Anxiety is useful - it can make you more alert or careful. It usually ends soon after you are out of the situation that caused it. But for millions of people in the United States, the Anxiety does not go away, and gets worse over time. They may have chest pains or nightmares. They may even be afraid to leave home. These people have Anxiety disorders. Types include

  • Panic disorder
  • Obsessive-compulsive disorder
  • Post-traumatic stress disorder
  • Phobias
  • Generalized Anxiety disorder

Treatment can involve medicines, therapy or both.

NIH: National Institute of Mental Health


Spironolactone Anxiety Reviews

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and Anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot.
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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