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Spironolactone Asthenia Side Effects

Spironolactone Asthenia Side Effect Reports


The following Spironolactone Asthenia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Asthenia, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Malaise, Fatigue, Asthenia, Heart Rate Irregular, Abdominal Pain, Gingival Bleeding, Oropharyngeal Pain, Pharyngeal Oedema, Swelling Face

This Asthenia side effect was reported by a consumer or non-health professional from US. A 54-year-old female patient (weight:NA) experienced the following symptoms/conditions: cardiac failure congestive. The patient was prescribed Spironolactone (dosage: 1 Pill, Daily, Mouth), which was started on Dec 04, 2013. Concurrently used drugs:
  • Alprazolam
  • Amitriptyline
  • Atorvastatin
  • Benicar
  • B12
  • Diphenoxylate
  • Folic Acid
  • Omeprazole
When starting to take Spironolactone the consumer reported the following symptoms:
  • Malaise
  • Fatigue
  • Asthenia
  • Heart Rate Irregular
  • Abdominal Pain
  • Gingival Bleeding
  • Oropharyngeal Pain
  • Pharyngeal Oedema
  • Swelling Face
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Dizziness, Asthenia, Renal Failure, Ventricular Extrasystoles

This Asthenia Spironolactone side effect was reported by a health professional from RU on Aug 19, 2013. A male , 75 years of age, was diagnosed with and was treated with Spironolactone. The patient presented the following health conditions:
  • Dizziness
  • Asthenia
  • Renal Failure
  • Ventricular Extrasystoles
. Spironolactone dosage: 50 Mg/day. Additional drugs used at the same time:
  • Enalapril (20 Mg/day)
  • Digoxin (0.375 Mg Daily)
  • Pradaxa (220 Mg/day)
  • Metoprolol Succinate (150 Mg Daily)
  • Amlodipine (2.5 Mg Daily)
  • Furosemide (80 Mg Daily)
  • Atorvastatin (20 Mg Daily)
  • Diabetone (30 Mg Daily)
The patient was hospitalized.
Dizziness, Mood Altered, Fatigue, Muscle Spasms, Muscular Weakness, Asthenia, Hypersensitivity, Abdominal Pain, Nausea

This is a Spironolactone side effect report of a 40-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Asthenia side effect. The patient presented with:
  • Dizziness
  • Mood Altered
  • Fatigue
  • Muscle Spasms
  • Muscular Weakness
  • Asthenia
  • Hypersensitivity
  • Abdominal Pain
  • Nausea
which developed after the beginning of treatment. The patient was hospitalized and became disabled. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from NA, resulting in Asthenia.

Cardiac Failure, Pneumonitis, Asthenia, Productive Cough, Pyrexia, Oedema, Anaemia, Dyspnoea Exertional

A 59-year-old patient (weight: NA) from ES with the following symptoms: NA started Spironolactone treatment (dosage: Daily Dose 25 Mg) on Jun 26, 2012. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Cardiac Failure
  • Pneumonitis
  • Asthenia
  • Productive Cough
  • Pyrexia
  • Oedema
  • Anaemia
  • Dyspnoea Exertional
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Asthenia.
Orthostatic Hypotension, Acute Prerenal Failure, Asthenia, Fall, Vision Blurred, Benign Prostatic Hyperplasia, Vitamin B Complex Deficiency, Mobility Decreased

A patient from US was prescribed and started Spironolactone on Mar 28, 2013. Patient felt the following Spironolactone side effects: orthostatic hypotension, acute prerenal failure, asthenia, fall, vision blurred, benign prostatic hyperplasia, vitamin b complex deficiency, mobility decreased Additional patient health information: male , 62 years of age, The consumer reported the following symptoms: . Spironolactone dosage: NA. Concurrently used drugs:
  • Saxagliptin
  • Humalog (insulin Lispro)
  • Lantus (insulin Glargine)
  • Lisinopril
  • Metoprolol
  • Aspirin (acetylsalicylic Acid)
  • Seroquel (quetiapine Fumarate)
  • Ezetimibe (ezetimibe) (tablet)
The patient was hospitalized.
Myocardial Infarction, Overdose, Blood Potassium Increased, Fatigue, Asthenia

This report suggests a potential Spironolactone Tablets Usp, 100 Mg (purepac) Asthenia side effect(s) that can have serious consequences. A 49-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone Tablets Usp, 100 Mg (purepac) (dosage: NA) starting Jan 15, 2012. Soon after starting Spironolactone Tablets Usp, 100 Mg (purepac) the patient began experiencing various side effects, including:
  • Myocardial Infarction
  • Overdose
  • Blood Potassium Increased
  • Fatigue
  • Asthenia
Drugs used concurrently:
  • Copaxone
  • Potassium
The patient was hospitalized. Although Spironolactone Tablets Usp, 100 Mg (purepac) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Asthenia, may still occur.
Asthenia, Hyperkalaemia

An adverse event was reported by a pharmacist on Nov 13, 2012 by a male taking Spironolactone (dosage: 25 Ml Bid Po) was diagnosed with and. Location: US , 56 years of age, weighting 227.7 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: asthenia, hyperkalaemia. Additional medications/treatments:
Associated medications used:
  • Ramipril (1.25 Mg Bid Po)
The patient was hospitalized.
Suicidal Ideation, Dyspnoea, Extrasystoles, Heart Rate Increased, Palpitations, Tremor, Hyperhidrosis, Feeling Hot, Asthenia

This Asthenia problem was reported by a consumer or non-health professional from US. A 71-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Spironolactone (dosage: 25 Mg, 1x/day). The following drugs/medications were being taken at the same time:
  • Sotalol (120 Mg, Daily)
  • Multaq (400 Mg, 2x/day)
  • Aspirin
  • Actonel
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Suicidal Ideation
  • Dyspnoea
  • Extrasystoles
  • Heart Rate Increased
  • Palpitations
  • Tremor
  • Hyperhidrosis
  • Feeling Hot
  • Asthenia
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Asthenia, may become evident only after a product is in use by the general population.
Renal Disorder, Renal Function Test Abnormal, Hair Texture Abnormal, Dry Skin, Dry Eye, Asthenia, Skin Odour Abnormal, Anosmia

This is a Spironolactone side effect report of a 66-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: hypertension,blood aldosterone decreased,blood potassium decreased and was treated with Spironolactone (dosage: 25 Mg, Unk) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Renal Disorder
  • Renal Function Test Abnormal
  • Hair Texture Abnormal
  • Dry Skin
  • Dry Eye
  • Asthenia
  • Skin Odour Abnormal
  • Anosmia
This opens a possibility that Spironolactone could cause Asthenia and that some female patients may be more susceptible.
Asthenia, Fatigue, Diarrhoea

This Asthenia side effect was reported by a health professional from UNITED STATES on Jun 22, 2012. A patient from UNITED STATES , 88 years of age, weighting 176.0 lb, was diagnosed with and was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: asthenia, fatigue, diarrhoea. Spironolactone dosage: 25 Mg 1 Daily Po. These side effects may potentially be related to Spironolactone.
Psychomotor Retardation, Coma Scale Abnormal, Psychiatric Symptom, Hyponatraemia, Malignant Peritoneal Neoplasm, Asthenia, Weight Decreased, Fall

This Asthenia side effect was reported by a health professional from FRANCE. A 85-year-old female patient (weight:NA) experienced the following symptoms/conditions: hypertension. The patient was prescribed Spironolactone (dosage: 1 Df;qd;po), which was started on Dec 15, 2011. Concurrently used drugs:
  • Polyethylene Glycol
  • Stalevo 50 (Po 5 Df;qd;po)
  • Stalevo 50 (Po 5 Df;qd;po)
  • Rabeprazole Sodium
  • Clopidogrel
  • Imovane
  • Lactulose
  • Oxazepam
When starting to take Spironolactone the consumer reported the following symptoms:
  • Psychomotor Retardation
  • Coma Scale Abnormal
  • Psychiatric Symptom
  • Hyponatraemia
  • Malignant Peritoneal Neoplasm
  • Asthenia
  • Weight Decreased
  • Fall
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Dyspnoea, Fluid Overload, Toxicity To Various Agents, Asthenia, Blood Urea Increased, Brain Natriuretic Peptide Increased, Fatigue, Hypotension, Glomerular Filtration Rate Decreased

This Asthenia Spironolactone side effect was reported by a physician from TAIWAN, PROVINCE OF CHINA on Apr 23, 2012. A male , 68 years of age, weighting 130.0 lb, was treated with Spironolactone. The patient presented the following health conditions:
  • Dyspnoea
  • Fluid Overload
  • Toxicity To Various Agents
  • Asthenia
  • Blood Urea Increased
  • Brain Natriuretic Peptide Increased
  • Fatigue
  • Hypotension
  • Glomerular Filtration Rate Decreased
. Spironolactone dosage: NA. Additional drugs used at the same time:
  • Digoxin (.25 Mg;qd;po)
The patient was hospitalized.
Myalgia, Arthralgia, Hypokalaemia, Asthenia

This is a Spironolactone side effect report of a 66-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: hypertension, who was treated with Spironolactone (dosage:25 Mg, start time: NS), combined with:
  • Hydrochlorothiazide (25 Mg, Daily)
, and developed a serious reaction and a Asthenia side effect. The patient presented with:
  • Myalgia
  • Arthralgia
  • Hypokalaemia
  • Asthenia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from hypertension, resulting in Asthenia.
Asthenia, Dyspnoea, Toxicity To Various Agents, Fatigue, Cardiac Failure Acute, Hypotension, Cardiac Failure Congestive, Fluid Overload

A patient (weight: NA) from TAIWAN, PROVINCE OF CHINA with the following symptoms: NA started Spironolactone treatment (dosage: NA) on Jan 06, 2010. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Asthenia
  • Dyspnoea
  • Toxicity To Various Agents
  • Fatigue
  • Cardiac Failure Acute
  • Hypotension
  • Cardiac Failure Congestive
  • Fluid Overload
. Concurrently used drugs:
  • Digoxin (25 Mg/per Day/oral)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Asthenia.
Sensation Of Heaviness, Asthenia, Oropharyngeal Pain, Paraesthesia, Fatigue

A patient from UNITED STATES was prescribed and started Spironolactone on Mar 06, 2012. After Spironolactone was administered, patient encountered several Spironolactone side effects: sensation of heaviness, asthenia, oropharyngeal pain, paraesthesia, fatigue Additional patient health information: male , 29 years of age, weighting 191.0 lb, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: 25 Mg. Concurrently used drugs: NA.
Heart Rate Decreased, Renal Failure, Rales, Asthenia, Atrioventricular Block, Hyperkalaemia, Respiratory Distress, Dyspnoea, Body Temperature Decreased

This report suggests a potential Spironolactone Asthenia side effect(s) that can have serious consequences. A 70-year-old patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: NA) starting NS. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Heart Rate Decreased
  • Renal Failure
  • Rales
  • Asthenia
  • Atrioventricular Block
  • Hyperkalaemia
  • Respiratory Distress
  • Dyspnoea
  • Body Temperature Decreased
Drugs used concurrently:
  • Insulin
  • Carvedilol
  • Valsartan
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Asthenia, may still occur.
Rectal Haemorrhage, Hypersensitivity, Asthenia, Oedema Peripheral, Malaise, Dyspnoea, Anaemia, Polyp, Joint Swelling

An adverse event was reported by a physician on Jan 03, 2012 by a Female taking Spironolactone (dosage: NA) was diagnosed with and. Location: UNITED STATES , 76 years of age, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: rectal haemorrhage, hypersensitivity, asthenia, oedema peripheral, malaise, dyspnoea, anaemia, polyp, joint swelling. Additional medications/treatments:
Multiple prescriptions taken:
  • Metoprolol Succinate
  • Brovana
  • Tracleer
  • Furosemide
The patient was hospitalized.
Myalgia, Back Pain, Asthenia, Pain In Extremity, Blood Potassium Increased

This Asthenia problem was reported by a consumer or non-health professional from UNITED STATES. A 79-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Sep 08, 2011 a consumer started treatment with Spironolactone (dosage: NA). The following drugs/medications were being taken at the same time:
  • Humira
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Myalgia
  • Back Pain
  • Asthenia
  • Pain In Extremity
  • Blood Potassium Increased
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Asthenia, may become evident only after a product is in use by the general population.
Asthenia, Dysstasia, Hyperkalaemia

This is a Spironolactone side effect report of a 64-year-old female patient (weight: NA) from CANADA. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: NA) starting NS. Concurrently used drugs:
  • Atacand
Soon after that, the consumer experienced the following of symptoms:
  • Asthenia
  • Dysstasia
  • Hyperkalaemia
The patient was hospitalized. This opens a possibility that Spironolactone could cause Asthenia and that some female patients may be more susceptible.
Hepatomegaly, Ascites, Hepatic Function Abnormal, Pruritus, Weight Decreased, Asthenia, Nausea, Flatulence, Jaundice

This Asthenia side effect was reported by a physician from HUNGARY on Nov 13, 2011. A patient from HUNGARY , 64 years of age, weighting 154.3 lb, was diagnosed with and was treated with Spironolactone. Patient felt the following Spironolactone side effects: hepatomegaly, ascites, hepatic function abnormal, pruritus, weight decreased, asthenia, nausea, flatulence, jaundice. Spironolactone dosage: 200 Mg, Qd.
Multiple prescriptions taken:
  • Clopidogrel (Unk)
  • Tramadol Hcl
  • Bisoprolol (5 Mg, Qd)
  • Nexavar (400 Mg, Bid)
  • Aspirin (100 Mg, Qd)
  • Furosemide (1 Df, Qd)
  • Xanax (0.25 Mg, Qd)
  • Atorvastatin (40 Mg, Qd)
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Asthenia Causes and Reviews


We are sorry, but no medical information on this topic currently exists in our database. Our articles are updated often, please revisit soon.


Spironolactone Asthenia Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
Blood Creatinine Increased (48)
Fatigue (46)
Hypotension (43)
Renal Failure (41)
Dizziness (40)
Pain (37)
Bradycardia (36)
Vomiting (33)
Hyponatraemia (33)
Oedema Peripheral (31)
Atrial Fibrillation (28)
Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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