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Spironolactone Cardiac Failure Side Effects

Spironolactone Cardiac Failure Side Effect Reports


The following Spironolactone Cardiac Failure side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Cardiac Failure, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Cardiac Failure, Pneumonitis, Asthenia, Productive Cough, Pyrexia, Oedema, Anaemia, Dyspnoea Exertional

This Cardiac Failure side effect was reported by a physician from ES. A 59-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Spironolactone (dosage: Daily Dose 25 Mg), which was started on Jun 26, 2012. Concurrently used drugs: NA. When starting to take Spironolactone the consumer reported the following symptoms:
  • Cardiac Failure
  • Pneumonitis
  • Asthenia
  • Productive Cough
  • Pyrexia
  • Oedema
  • Anaemia
  • Dyspnoea Exertional
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Pulmonary Congestion, Oliguria, Blood Sodium Decreased, Syncope, Hepatic Congestion, Cardiac Failure, Bundle Branch Block Left, Hypotension, Atrioventricular Block First Degree

This Cardiac Failure Spironolactone side effect was reported by a physician from BRAZIL on Dec 14, 2005. A male , 50 years of age, was treated with Spironolactone. The patient presented the following health conditions:
  • Pulmonary Congestion
  • Oliguria
  • Blood Sodium Decreased
  • Syncope
  • Hepatic Congestion
  • Cardiac Failure
  • Bundle Branch Block Left
  • Hypotension
  • Atrioventricular Block First Degree
. Spironolactone dosage: NA. Additional drugs used at the same time:
  • Hidralazine (hydralazine)
  • Tolvaptan (tolvaptan(v4.1)) 30mg (30 Mg, Qd, Oral)
  • Isosorbide Mononitrate
  • Furosemide
The patient was hospitalized.
Cardiac Failure

This is a Spironolactone side effect report of a female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: cardiac failure chronic, who was treated with Spironolactone (dosage:25 Mg, Unk, start time: Aug 05, 2002), combined with:
  • Furosemide
, and developed a serious reaction and a Cardiac Failure side effect. The patient presented with:
  • Cardiac Failure
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from cardiac failure chronic, resulting in Cardiac Failure.

Arrhythmia, Oedema, Dyspnoea, Renal Failure Chronic, Mitral Valve Incompetence, Cardiac Failure, Blood Pressure Decreased

A female patient (weight: NA) from GERMANY with the following symptoms: oedema,hypertension started Spironolactone treatment (dosage: 50 Mg, Per Day) on Sep 10, 2010. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Arrhythmia
  • Oedema
  • Dyspnoea
  • Renal Failure Chronic
  • Mitral Valve Incompetence
  • Cardiac Failure
  • Blood Pressure Decreased
. Concurrently used drugs:
  • Lisinopril (10 Mg, Per Day)
  • Bisoprolol (10 Mg, Per Day)
  • Torsemide (10 Mg, Qd)
  • Beta Blocking Agents
  • Anticoagulants
  • Calcium Channel Blockers
  • Amiodarone Hcl (200 Mg, Per Day)
  • Rasilez (300 Mg, Per Day)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Cardiac Failure.
Bacteraemia, Pulmonary Oedema, Atrial Fibrillation, Palpitations, Device Related Infection, Hyperkalaemia, Staphylococcal Bacteraemia, Cardiac Failure, Brain Natriuretic Peptide Increased

A patient from UNITED STATES was prescribed and started Spironolactone on Jan 06, 2012. Patient felt the following Spironolactone side effects: bacteraemia, pulmonary oedema, atrial fibrillation, palpitations, device related infection, hyperkalaemia, staphylococcal bacteraemia, cardiac failure, brain natriuretic peptide increased Additional patient health information: male , 83 years of age, weighting 206.8 lb, The consumer reported the following symptoms: . Spironolactone dosage: NA. Concurrently used drugs:
  • Provenge (250 Ml, Single, Intravenous)
  • Atenolol
  • Amlodipine
  • Denosumab
  • Lisinopril
  • Selenium
  • Lupron
  • Acetylsalicylic Acid Srt
The patient was hospitalized.
Cardiac Murmur, Cardiac Failure, Pneumonia, Pulmonary Artery Dilatation, Sinus Rhythm, Coronary Artery Stenosis, Right Ventricular Failure, Pulmonary Alveolar Haemorrhage

This report suggests a potential Spironolactone Cardiac Failure side effect(s) that can have serious consequences. A 56-year-old female patient from JAPAN (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: 25mg Per Day) starting Jan 01, 2008. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Cardiac Murmur
  • Cardiac Failure
  • Pneumonia
  • Pulmonary Artery Dilatation
  • Sinus Rhythm
  • Coronary Artery Stenosis
  • Right Ventricular Failure
  • Pulmonary Alveolar Haemorrhage
Drugs used concurrently:
  • Flolan
  • Aspirin (1iuax Per Day)
  • Denopamine (40mg Per Day)
  • Pimobendan (5mg Per Day)
  • Tadalafil
  • Metildigoxin (1iuax Per Day)
  • Metildigoxin (1iuax Per Day)
Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cardiac Failure, may still occur.
Hyperkalaemia, Pleural Effusion, Device Related Infection, Left Ventricular Dysfunction, Atrial Fibrillation, Pulmonary Oedema, Cardiac Failure, Staphylococcus Test Positive

An adverse event was reported by a health professional on Dec 16, 2011 by a male taking Spironolactone (dosage: Unk) . Location: UNITED STATES , weighting 207.1 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: hyperkalaemia, pleural effusion, device related infection, left ventricular dysfunction, atrial fibrillation, pulmonary oedema, cardiac failure, staphylococcus test positive. Additional medications/treatments:
Associated medications used:
  • Lupron
  • Folic Acid (Unk)
  • Selenium (Unk)
  • Provenge (250 Ml)
  • Amlodipine (Unk)
  • Denosumab (Unk)
  • Furosemide (Unk)
  • Citrical + D
Pathogen Resistance, Diarrhoea, Cardiac Failure, Sputum Culture Positive

This Cardiac Failure problem was reported by a physician from NETHERLANDS. A patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Feb 10, 2011 a consumer started treatment with Spironolactone (dosage: NA). The following drugs/medications were being taken at the same time:
  • Revatio
  • Treprostinil
  • Sintrom
  • Tracleer (250 Mg, Qd)
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Pathogen Resistance
  • Diarrhoea
  • Cardiac Failure
  • Sputum Culture Positive
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Cardiac Failure, may become evident only after a product is in use by the general population.
Disease Progression, Cardiac Failure, Condition Aggravated

This is a Spironolactone side effect report of a 73-year-old patient (weight: NA) from ARGENTINA. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: NA) starting Mar 30, 2009. Concurrently used drugs:
  • Warfarin Sodium (2 Milligram 1 Day Oral)
  • Enalapril Maleate
  • Amiodarone (amiodarone Hcl)
Soon after that, the consumer experienced the following of symptoms:
  • Disease Progression
  • Cardiac Failure
  • Condition Aggravated
The patient was hospitalized. This opens a possibility that Spironolactone could cause Cardiac Failure and that some patients may be more susceptible.
Pulmonary Oedema, Cardiac Failure

This Cardiac Failure side effect was reported by a consumer or non-health professional from ARGENTINA on Jun 22, 2011. A patient from ARGENTINA , 80 years of age, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: pulmonary oedema, cardiac failure. Spironolactone dosage: NA.
Associated medications used:
  • Metformin Hcl
  • Enalapril Maleate
  • Stalevo 100 (Strength 50 Mg; 50 Mg Four Tablets Daily Oral ; 100 Mg Four Tablets Daily Oral)
  • Furosemide
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Altered State Of Consciousness, Amyloidosis, Cardiac Failure, Musculoskeletal Stiffness, Dry Eye, Hypoaesthesia, Weight Increased, Pain, Cardiac Failure Congestive

This Cardiac Failure side effect was reported by a physician from SWITZERLAND. A 61-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Spironolactone (dosage: NA), which was started on Jan 21, 2011. Concurrently used drugs:
  • Methotrexate
  • Vicodin (1-1 1/2 Tablets Qid Prn)
  • Hydralazine Hcl
  • Arava
  • Synthroid
  • Methotrexate
  • Novalgin
  • Trazodone Hcl (Qhs)
When starting to take Spironolactone the consumer reported the following symptoms:
  • Altered State Of Consciousness
  • Amyloidosis
  • Cardiac Failure
  • Musculoskeletal Stiffness
  • Dry Eye
  • Hypoaesthesia
  • Weight Increased
  • Pain
  • Cardiac Failure Congestive
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Cardiac Disorder, Convulsion, Cardiomegaly, Dyspnoea, Cardiac Failure

This Cardiac Failure Spironolactone side effect was reported by a consumer or non-health professional from BRAZIL on May 10, 2011. A Female , weighting 90.39 lb, was diagnosed with and was treated with Spironolactone. The patient presented the following health conditions:
  • Cardiac Disorder
  • Convulsion
  • Cardiomegaly
  • Dyspnoea
  • Cardiac Failure
. Spironolactone dosage: NA. Additional drugs used at the same time:
  • Enalapril
  • Digoxin (1/2 - 0.25 Mg Per Day (0.125 Mg Daily))
  • Raloxifene Hcl
  • Carvedilol
  • Furosemide
  • Humira
  • Puran T4
  • Calcium
The patient was hospitalized.
Cardiac Failure

This is a Spironolactone side effect report of a 8-year-old female patient (weight:NA) from JAPAN, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:NA, start time: NS), combined with:
  • Furosemide
, and developed a serious reaction and a Cardiac Failure side effect. The patient presented with:
  • Cardiac Failure
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from NA, resulting in Cardiac Failure.
Acute Myocardial Infarction, Cardiac Failure, Dehydration, Diarrhoea, Renal Failure Acute, Vascular Insufficiency

A 59-year-old female patient (weight: NA) from GERMANY with the following symptoms: renal failure chronic started Spironolactone treatment (dosage: 50 Mg; Po) on Dec 01, 2009. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Acute Myocardial Infarction
  • Cardiac Failure
  • Dehydration
  • Diarrhoea
  • Renal Failure Acute
  • Vascular Insufficiency
. Concurrently used drugs:
  • Ramipril (50 Mg; Po)
  • Hydrochlorothiazide (25 Mg; Po)
  • Bisoprolol
  • Torasemide
  • Simvastatin
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Cardiac Failure.
Cardiac Failure, Depression, Hypotension

A patient from GERMANY was prescribed and started Spironolactone on Feb 24, 2009. After Spironolactone was administered, patient encountered several Spironolactone side effects: cardiac failure, depression, hypotension Additional patient health information: male , 67 years of age, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: 50 Mg;daily;oral. Concurrently used drugs:
  • Torasemide (torasemide) (200 Mg) (200 Mg;twice A Day;oral)
  • Celebrex
  • Metformin Hcl
  • Spiriva
  • Thiamazole
  • Viani
The patient was hospitalized.
Arteritis, Cardiac Failure, Cardiac Murmur, Haemoglobin Decreased, Oedema Peripheral, Thrombocytopenia

This report suggests a potential Spironolactone Cardiac Failure side effect(s) that can have serious consequences. A 97-year-old female patient from SWEDEN (weight:NA) was diagnosed with the following health condition(s): cardiac failure and used Spironolactone (dosage: 25 Mg; Qd; Po) starting Dec 03, 2007. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Arteritis
  • Cardiac Failure
  • Cardiac Murmur
  • Haemoglobin Decreased
  • Oedema Peripheral
  • Thrombocytopenia
Drugs used concurrently:
  • Diclofenac Sodium (50 Mg, Qd; Po)
  • Impugan
  • Voltaren
  • Atarax
  • Acetaminophen
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cardiac Failure, may still occur.
Cardiac Failure, Condition Aggravated, Hyperkalaemia, Hypotension, Pulmonary Oedema, Renal Impairment, Syncope

An adverse event was reported by a consumer or non-health professional on Jan 18, 2008 by a male taking Spironolactone (dosage: NA) was diagnosed with and. Location: NETHERLANDS , 91 years of age, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: cardiac failure, condition aggravated, hyperkalaemia, hypotension, pulmonary oedema, renal impairment, syncope. Additional medications/treatments: The patient was hospitalized.
Cardiac Failure, Condition Aggravated, Dizziness, Renal Failure Chronic

This Cardiac Failure problem was reported by a pharmacist from UNITED STATES. A patient (weight: NA) was diagnosed with the following medical condition(s): cardiac failure.On Jan 09, 2001 a consumer started treatment with Spironolactone (dosage: 25 Mg Daily Po). The following drugs/medications were being taken at the same time:
  • Lisinopril (40 Mg Daily Po)
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Cardiac Failure
  • Condition Aggravated
  • Dizziness
  • Renal Failure Chronic
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Cardiac Failure, may become evident only after a product is in use by the general population.
Anaemia, Angina Pectoris, Angiopathy, Benign Prostatic Hyperplasia, Blood Pressure Diastolic Decreased, Cardiac Failure, Dyspnoea, Faeces Discoloured

This is a Spironolactone side effect report of a 78-year-old patient (weight: NA) from NETHERLANDS. The patient developed the following symptoms/conditions: ill-defined disorder and was treated with Spironolactone (dosage: 12.5 Mg (12.5 Mg, Daily), Oral) starting NS. Concurrently used drugs:
  • Aspirin
  • Coversyl (perindopril) (1 Mg (1 Mg, Qd), Oral)
  • Bumetanide (2 Mg (2 Md, Daily), Oral)
  • Acenocoumarol (acenocoumarol)
  • Digoxin (0.125 Mg)
  • Atenolol
  • Simvastatin
  • Dutasteride (dutasteride)
Soon after that, the consumer experienced the following of symptoms:
  • Anaemia
  • Angina Pectoris
  • Angiopathy
  • Benign Prostatic Hyperplasia
  • Blood Pressure Diastolic Decreased
  • Cardiac Failure
  • Dyspnoea
  • Faeces Discoloured
The patient was hospitalized. This opens a possibility that Spironolactone could cause Cardiac Failure and that some patients may be more susceptible.
Blood Alkaline Phosphatase Increased, Cardiac Failure, Gamma-glutamyltransferase Increased, Haemoptysis, Pneumonia

This Cardiac Failure side effect was reported by a health professional from SWEDEN on Apr 12, 2006. A patient from SWEDEN , 59 years of age, was diagnosed with and was treated with Spironolactone. Patient felt the following Spironolactone side effects: blood alkaline phosphatase increased, cardiac failure, gamma-glutamyltransferase increased, haemoptysis, pneumonia. Spironolactone dosage: 25 Mg (25 Mg, Daily), Oral.
Multiple prescriptions taken:
  • Tracleer (125 Mg (daily), Oral)
  • Cozaar (80 Mg (daily), Oral)
  • Warfarin Sodium
  • Midamor
  • Furosemide
  • Emconcor Chf (bisoprolol Fumarate)
The patient was hospitalized. These side effects may potentially be related to Spironolactone.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Cardiac Failure Causes and Reviews


Heart failure is a condition in which the heart can't pump enough blood to meet the body's needs. Heart failure does not mean that your heart has stopped or is about to stop working. It means that your heart is not able to pump blood the way it should. It can affect one or both sides of the heart.

The weakening of the heart's pumping ability causes

  • Blood and fluid to back up into the lungs
  • The buildup of fluid in the feet, ankles and legs - called edema
  • Tiredness and shortness of breath

Common causes of heart failure are coronary artery disease, high blood pressure and diabetes. It is more common in people who are 65 years old or older, African Americans, people who are overweight, and people who have had a heart attack. Men have a higher rate of heart failure than women.

Your doctor will diagnose heart failure by doing a physical exam and heart tests. Treatment includes treating the underlying cause of your heart failure, medicines, and heart transplantation if other treatments fail.

NIH: National Heart, Lung, and Blood Institute


Spironolactone Cardiac Failure Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
Blood Creatinine Increased (48)
Fatigue (46)
Hypotension (43)
Renal Failure (41)
Dizziness (40)
Pain (37)
Bradycardia (36)
Vomiting (33)
Hyponatraemia (33)
Oedema Peripheral (31)
Atrial Fibrillation (28)
Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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