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Spironolactone Hypokalaemia Side Effects

Spironolactone Hypokalaemia Side Effect Reports


The following Spironolactone Hypokalaemia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Hypokalaemia, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Hypophosphataemia, Neutropenia, Hypokalaemia, Leukopenia

This Hypokalaemia side effect was reported by a health professional from QA. A 51-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Spironolactone (dosage: NA), which was started on 201205. Concurrently used drugs:
  • Methylprednisolone (On Days 1-4)
  • Etoposide (On Days 1-4)
  • Cisplatin (Given As Continuous Infusion On Days 1-4)
  • Furosemide
  • Cytarabine (On Day 5)
  • Filgrastim
  • Filgrastim
  • Entecavir
When starting to take Spironolactone the consumer reported the following symptoms:
  • Hypophosphataemia
  • Neutropenia
  • Hypokalaemia
  • Leukopenia
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Pulmonary Hypertension, Ventricular Hypokinesia, Dilatation Ventricular, Electrocardiogram St-t Change, Hypokalaemia

This Hypokalaemia Spironolactone side effect was reported by a physician from RUSSIAN FEDERATION on Feb 06, 2006. A male , 70 years of age, was treated with Spironolactone. The patient presented the following health conditions:
  • Pulmonary Hypertension
  • Ventricular Hypokinesia
  • Dilatation Ventricular
  • Electrocardiogram St-t Change
  • Hypokalaemia
. Spironolactone dosage: NA. Additional drugs used at the same time:
  • Enalapril Maleate
  • Asparcam (kalium Aspartate, Magnesium Aspartate)
  • Tolvaptan (tolvaptan(v4.1)) 30mg (30 Mg, Qd, Oral)
  • Tolvaptan (tolvaptan(v4.1)) 30mg (30 Mg, Qd, Oral)
  • Atenolol
The patient was hospitalized.
Fall, Inappropriate Antidiuretic Hormone Secretion, Hypokalaemia

This is a Spironolactone side effect report of a 86-year-old female patient (weight:NA) from FRANCE, suffering from the following symptoms/conditions: hypertension, who was treated with Spironolactone (dosage:Oral, start time: NS), combined with:
  • Aspegic (acetylsalicylate Lysine)
  • Aceon (2.5 Mg, Unk, Oral)
, and developed a serious reaction and a Hypokalaemia side effect. The patient presented with:
  • Fall
  • Inappropriate Antidiuretic Hormone Secretion
  • Hypokalaemia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from hypertension, resulting in Hypokalaemia.

Torsade De Pointes, Hypokalaemia, Cardiac Arrest, Electrocardiogram U-wave Abnormality, Blood Creatinine Increased, Atrial Fibrillation, Ventricular Tachycardia, Electrocardiogram Qt Prolonged

A 62-year-old female patient (weight: NA) from FRANCE with the following symptoms: NA started Spironolactone treatment (dosage: 50/20mg) on Sep 09, 2010. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Torsade De Pointes
  • Hypokalaemia
  • Cardiac Arrest
  • Electrocardiogram U-wave Abnormality
  • Blood Creatinine Increased
  • Atrial Fibrillation
  • Ventricular Tachycardia
  • Electrocardiogram Qt Prolonged
. Concurrently used drugs:
  • Formoterol W/budesonide
  • Cetirizine (10mg)
  • Rabeprazole Sodium (20mg)
  • Diltiazem (200mg)
  • Albuterol
  • Metformin Hcl (1700mg)
  • Fluoxetine (20mg)
  • Procoralan
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Hypokalaemia.
Myalgia, Arthralgia, Hypokalaemia, Asthenia

A female patient from UNITED STATES was prescribed and started Spironolactone on Apr 17, 2012. Patient felt the following Spironolactone side effects: myalgia, arthralgia, hypokalaemia, asthenia Additional patient health information: Female , 66 years of age, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: 25 Mg. Concurrently used drugs:
  • Hydrochlorothiazide (25 Mg, Daily)
The patient was hospitalized.
Condition Aggravated, Pain, Rhabdomyolysis, Gynaecomastia, Muscular Weakness, Hypokalaemia, Adrenal Adenoma

This report suggests a potential Spironolactone Hypokalaemia side effect(s) that can have serious consequences. A 48-year-old patient from UNITED KINGDOM (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: NA) starting NS. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Condition Aggravated
  • Pain
  • Rhabdomyolysis
  • Gynaecomastia
  • Muscular Weakness
  • Hypokalaemia
  • Adrenal Adenoma
Drugs used concurrently:
  • Lisinopril
  • Chlorthalidone (25 Mg, Unk)
  • Lercanidipine
  • Chlorthalidone (Titrated Upto 50 Mg, Unk)
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypokalaemia, may still occur.
Amnesia, Daydreaming, Confusional State, Hypokalaemia, Electrolyte Imbalance

An adverse event was reported by a consumer or non-health professional on Nov 04, 2011 by a Female taking Spironolactone (dosage: 1 Tablet, Qd, Oral) was diagnosed with and. Location: UNITED STATES , 72 years of age, weighting 94.00 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: amnesia, daydreaming, confusional state, hypokalaemia, electrolyte imbalance. Additional medications/treatments:
Associated medications used:
  • Spiriva
  • Buttox Injection
  • Colace
  • Lisinopril
  • Aldamate
  • Trazodone Hcl
  • Hydrochlorothiazide
  • Xanoflax
The patient was hospitalized.
Renal Tubular Disorder, Metabolic Alkalosis, Decreased Appetite, Bone Marrow Failure, Malaise, Hypokalaemia, Hypomagnesaemia, Dehydration, Nausea

This Hypokalaemia problem was reported by a health professional from JAPAN. A 44-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jun 01, 2009 a consumer started treatment with Spironolactone (dosage: 25 Mg, Unk). The following drugs/medications were being taken at the same time:
  • Sennoside (0.5 Mg, Unk)
  • Estazolam (2 Mg, Unk)
  • Zoledronic (4 Mg, Unk)
  • Diclofenac Sodium (7.5 Mg, Unk)
  • Ts 1 (100 Mg, Unk)
  • Omeprazole (20 Mg, Unk)
  • Cisplatin (80 Mg, Unk)
  • Furosemide (40 Mg, Unk)
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Renal Tubular Disorder
  • Metabolic Alkalosis
  • Decreased Appetite
  • Bone Marrow Failure
  • Malaise
  • Hypokalaemia
  • Hypomagnesaemia
  • Dehydration
  • Nausea
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Hypokalaemia, may become evident only after a product is in use by the general population.
Blood Creatine Phosphokinase Increased, Hypokalaemia

This is a Spironolactone side effect report of a 58-year-old patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: cardiac failure and was treated with Spironolactone (dosage: NA) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Blood Creatine Phosphokinase Increased
  • Hypokalaemia
The patient was hospitalized. This opens a possibility that Spironolactone could cause Hypokalaemia and that some patients may be more susceptible.
Asthenia, Hypokalaemia, Blood Pressure Decreased

This Hypokalaemia side effect was reported by a health professional from PORTUGAL on Aug 31, 2011. A female patient from PORTUGAL , 58 years of age, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: asthenia, hypokalaemia, blood pressure decreased. Spironolactone dosage: 50 Mg, Unk.
Associated medications used:
  • Potassium Chloride (1200 Mg, Tid)
  • Bupropion Hcl
  • Rosuvastatin
  • Chlorthalidone
  • Omeprazole
  • Paroxetine Hcl
  • Bromazepam
These side effects may potentially be related to Spironolactone.
Dehydration, Hypokalaemia, Renal Failure

This Hypokalaemia side effect was reported by a pharmacist from UNITED STATES. A 80-year-old patient (weight:NA) experienced the following symptoms/conditions: cardiac failure congestive,hypertension,oedema. The patient was prescribed Spironolactone (dosage: 25 Mg Daily), which was started on Jul 21, 2005. Concurrently used drugs: NA. When starting to take Spironolactone the consumer reported the following symptoms:
  • Dehydration
  • Hypokalaemia
  • Renal Failure
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Hypokalaemia, Treatment Noncompliance

This Hypokalaemia Spironolactone side effect was reported by a pharmacist from UNITED STATES on Nov 16, 2005. A Female , 47 years of age, weighting 135.8 lb, was diagnosed with and was treated with Spironolactone. The patient presented the following health conditions:
  • Hypokalaemia
  • Treatment Noncompliance
. Spironolactone dosage: 100mg Bid Po. Additional drugs used at the same time: NA. The patient was hospitalized.
Blood Pressure Systolic Decreased, Brain Natriuretic Peptide Increased, Condition Aggravated, Dizziness Exertional, Dizziness Postural, Epigastric Discomfort, Hypokalaemia, Iron Deficiency Anaemia

This is a Spironolactone side effect report of a 36-year-old female patient (weight:NA) from , suffering from the following symptoms/conditions: right ventricular failure, who was treated with Spironolactone (dosage:See Image, start time: Oct 15, 1997), combined with: NA., and developed a serious reaction and a Hypokalaemia side effect. The patient presented with:
  • Blood Pressure Systolic Decreased
  • Brain Natriuretic Peptide Increased
  • Condition Aggravated
  • Dizziness Exertional
  • Dizziness Postural
  • Epigastric Discomfort
  • Hypokalaemia
  • Iron Deficiency Anaemia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from right ventricular failure, resulting in Hypokalaemia.
Anorexia, Asthenia, Chest Pain, Constipation, Cough, Hyperkalaemia, Hypokalaemia, Hyponatraemia, Lobar Pneumonia

A 70-year-old patient (weight: NA) from with the following symptoms: hypertension started Spironolactone treatment (dosage: NA) on NS. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Anorexia
  • Asthenia
  • Chest Pain
  • Constipation
  • Cough
  • Hyperkalaemia
  • Hypokalaemia
  • Hyponatraemia
  • Lobar Pneumonia
. Concurrently used drugs:
  • Furosemide
  • Metolazone
  • Losartan (losartan)
  • Ceftriaxone
  • Cefuroxime
  • Gentamicin
  • Ceftazidime Sodium
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Hypokalaemia.
Abasia, Anorexia, Asthenia, Constipation, Hypokalaemia, Hyponatraemia, Lobar Pneumonia, Lung Infection Pseudomonal, Pathogen Resistance

A patient from was prescribed and started Spironolactone on Feb 15, 2005. After Spironolactone was administered, patient encountered several Spironolactone side effects: abasia, anorexia, asthenia, constipation, hypokalaemia, hyponatraemia, lobar pneumonia, lung infection pseudomonal, pathogen resistance Additional patient health information: male , 70 years of age, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: NA. Concurrently used drugs:
  • Furosemide
  • Metolazone
  • Losartan (losartan)
  • Ceftriaxone
  • Cefuroxime
  • Gentamicin
  • Ceftazidime Sodium
The patient was hospitalized.
Anorexia, Asthenia, Constipation, Effusion, Hyperkalaemia, Hypokalaemia, Hyponatraemia, Pneumonia, Pseudomonas Infection

This report suggests a potential Spironolactone Hypokalaemia side effect(s) that can have serious consequences. A 70-year-old patient from (weight:NA) was diagnosed with the following health condition(s): hypertension and used Spironolactone (dosage: NA) starting NS. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Anorexia
  • Asthenia
  • Constipation
  • Effusion
  • Hyperkalaemia
  • Hypokalaemia
  • Hyponatraemia
  • Pneumonia
  • Pseudomonas Infection
Drugs used concurrently:
  • Furosemide (furosemide)
  • Metolazone
  • Losartan (losartan)
  • Ceftriaxone
  • Cefuroxime
  • Gentamicin
  • Ceftazide (ceftazidime)
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypokalaemia, may still occur.
Adrenal Adenoma, Atrial Fibrillation, Cerebral Artery Embolism, Electrocardiogram St Segment Depression, Hypokalaemia, Ischaemic Stroke, Leukoencephalopathy, Metabolic Alkalosis, Primary Hyperaldosteronism

An adverse event was reported by a physician on Jan 14, 2005 by a Female taking Spironolactone (dosage: Oral) was diagnosed with and. Location: , 67 years of age, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: adrenal adenoma, atrial fibrillation, cerebral artery embolism, electrocardiogram st segment depression, hypokalaemia, ischaemic stroke, leukoencephalopathy, metabolic alkalosis, primary hyperaldosteronism. Additional medications/treatments:
Multiple prescriptions taken:
  • Aspirin
  • Heparin
  • Beta Blocking Agents (beta Blocking Agents)
The patient was hospitalized.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Hypokalaemia Causes and Reviews


Potassium is a mineral that your body needs to work properly. It is a type of electrolyte. It helps your nerves to function and muscles to contract. It helps your heartbeat stay regular. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Many people get all the potassium they need from what they eat and drink. Sources of potassium in the diet include

  • Leafy greens, such as spinach and collards
  • Fruit from vines, such as grapes and blackberries
  • Root vegetables, such as carrots and potatoes
  • Citrus fruits, such as oranges and grapefruit

Your kidneys help to keep the right amount of potassium in your body. If you have chronic kidney disease, your kidneys may not remove extra potassium from the blood. Some medicines also can raise your potassium level. You may need a special diet to lower the amount of potassium that you eat.


Spironolactone Hypokalaemia Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
Blood Creatinine Increased (48)
Fatigue (46)
Hypotension (43)
Renal Failure (41)
Dizziness (40)
Pain (37)
Bradycardia (36)
Vomiting (33)
Hyponatraemia (33)
Oedema Peripheral (31)
Atrial Fibrillation (28)
Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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