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Spironolactone Hyponatraemia Side Effects

Spironolactone Hyponatraemia Side Effect Reports


The following Spironolactone Hyponatraemia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Hyponatraemia, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Hyponatraemia, Delirium

This Hyponatraemia side effect was reported by a physician from JP. A 89-year-old female patient (weight:NA) experienced the following symptoms/conditions: cardiac failure chronic. The patient was prescribed Spironolactone (dosage: Unk), which was started on NS. Concurrently used drugs:
  • Furosemide
When starting to take Spironolactone the consumer reported the following symptoms:
  • Hyponatraemia
  • Delirium
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
International Normalised Ratio Increased, Hyponatraemia

This Hyponatraemia Spironolactone side effect was reported by a pharmacist from GB on Nov 20, 2013. A male , 65 years of age, was diagnosed with and was treated with Spironolactone. The patient presented the following health conditions:
  • International Normalised Ratio Increased
  • Hyponatraemia
. Spironolactone dosage: 25 Mg Once Per Day In The Morning. Additional drugs used at the same time:
  • Furosemide (60mg Am + 40mg Lunchtime)
  • Omeprazole (40 Mg, 1x/day Morning)
  • Warfarin (4mg/5mg Alternate Days)
  • Digoxin (Unk)
  • Tiotropium (Unk)
  • Symbicort (Unk)
  • Paracetamol (Unk)
  • Salbutamol (Unk)
The patient was hospitalized.
Hyponatraemia, Balance Disorder, Confusional State

This is a Spironolactone side effect report of a 79-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:25 Mg, Unk, start time: NS), combined with:
  • Lansoprazole (15 Mg, 1x/day)
  • Furosemide (80 Mg, 1x/day)
  • Oxcarbazepine (300mg Once In The Morning, 600mg Once At Night)
  • Levetiracetam
  • Calcichew-d3
  • Paracetamol
  • Warfarin
  • Betahistine
, and developed a serious reaction and a Hyponatraemia side effect. The patient presented with:
  • Hyponatraemia
  • Balance Disorder
  • Confusional State
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from NA, resulting in Hyponatraemia.

Hyponatraemia, Inappropriate Antidiuretic Hormone Secretion

A 65-year-old patient (weight: NA) from US with the following symptoms: NA started Spironolactone treatment (dosage: Mg Every Day Po) on Jun 25, 2012. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Hyponatraemia
  • Inappropriate Antidiuretic Hormone Secretion
. Concurrently used drugs:
  • Diclofenac
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Hyponatraemia.
Fall, Upper Limb Fracture, Haemarthrosis, Hyponatraemia, Vitamin D Deficiency

A female patient from FR was prescribed and started Spironolactone on Sep 18, 2012. Patient felt the following Spironolactone side effects: fall, upper limb fracture, haemarthrosis, hyponatraemia, vitamin d deficiency Additional patient health information: Female , 77 years of age, The consumer reported the following symptoms: . Spironolactone dosage: Unk. Concurrently used drugs:
  • Paroxetine (Unk)
  • Vastarel (Unk)
  • Previscan (Unk)
The patient was hospitalized.
Psychomotor Retardation, Coma Scale Abnormal, Psychiatric Symptom, Hyponatraemia, Malignant Peritoneal Neoplasm, Asthenia, Weight Decreased, Fall

This report suggests a potential Spironolactone Hyponatraemia side effect(s) that can have serious consequences. A 85-year-old female patient from FRANCE (weight:NA) was diagnosed with the following health condition(s): hypertension and used Spironolactone (dosage: 1 Df;qd;po) starting Dec 15, 2011. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Psychomotor Retardation
  • Coma Scale Abnormal
  • Psychiatric Symptom
  • Hyponatraemia
  • Malignant Peritoneal Neoplasm
  • Asthenia
  • Weight Decreased
  • Fall
Drugs used concurrently:
  • Polyethylene Glycol
  • Stalevo 50 (Po 5 Df;qd;po)
  • Stalevo 50 (Po 5 Df;qd;po)
  • Rabeprazole Sodium
  • Clopidogrel
  • Imovane
  • Lactulose
  • Oxazepam
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hyponatraemia, may still occur.
Subclavian Vein Thrombosis, Disease Progression, Hyponatraemia

An adverse event was reported by a health professional on Feb 07, 2012 by a male taking Spironolactone (dosage: NA) was diagnosed with and. Location: AUSTRALIA , weighting 187.2 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: subclavian vein thrombosis, disease progression, hyponatraemia. Additional medications/treatments:
Associated medications used:
  • Oxycontin
  • Vemurafenib
  • Atorvastatin
  • Enoxaparin
  • Diltiazem Hcl
The patient was hospitalized.
Hyponatraemia, Mental Status Changes

This Hyponatraemia problem was reported by a health professional from UNITED STATES. A patient (weight: NA) was diagnosed with the following medical condition(s): hypertension,anxiety,anaemia,oedema peripheral,pain,prostate cancer.On Jan 01, 2005 a consumer started treatment with Spironolactone W/ Hydrochlorothiazide (dosage: Unk). The following drugs/medications were being taken at the same time:
  • Xanax (Unk)
  • Iron Sulfatethiamin Compound Tab (Unk)
  • Potassium Chloride (Unk)
  • Oxycodone Hydrochloride (Unk)
  • Prednisone Tab (5 Mg, 2x/day)
  • Lasix (Unk)
  • Restoril (Unk)
  • Avapro (Unk)
When commencing Spironolactone W/ Hydrochlorothiazide, the patient experienced the following unwanted symptoms /side effects:
  • Hyponatraemia
  • Mental Status Changes
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Hyponatraemia, may become evident only after a product is in use by the general population.
Hyponatraemia, Cardiac Arrest

This is a Spironolactone side effect report of a 66-year-old patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: NA) starting NS. Concurrently used drugs:
  • Dopamine
Soon after that, the consumer experienced the following of symptoms:
  • Hyponatraemia
  • Cardiac Arrest
This opens a possibility that Spironolactone could cause Hyponatraemia and that some patients may be more susceptible.
Transient Ischaemic Attack, Hyponatraemia

This Hyponatraemia side effect was reported by a health professional from FRANCE on Aug 31, 2011. A female patient from FRANCE , 79 years of age, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: transient ischaemic attack, hyponatraemia. Spironolactone dosage: Long Term.
Associated medications used:
  • Omeprazole (Long Term)
  • Furosemide (Long Term)
These side effects may potentially be related to Spironolactone.
Weight Increased, Hyponatraemia

This Hyponatraemia side effect was reported by a pharmacist from JAPAN. A 40-year-old patient (weight:NA) experienced the following symptoms/conditions: cardiac failure,wound infection staphylococcal. The patient was prescribed Spironolactone (dosage: 25 Mg, 1x/day), which was started on Mar 21, 2009. Concurrently used drugs:
  • Zyvox (1200 Mg, 1x/day)
  • Zyvox (1200 Mg, 1x/day)
  • Lasix (10 Mg, 1x/day)
  • Trichlormethiazide (2 Mg, 1x/day)
When starting to take Spironolactone the consumer reported the following symptoms:
  • Weight Increased
  • Hyponatraemia
These side effects may potentially be related to Spironolactone.
Hyponatraemia, Weight Increased

This Hyponatraemia Spironolactone side effect was reported by a physician from JAPAN on Jul 20, 2011. A male , 40 years of age, weighting 132.3 lb, was diagnosed with and was treated with Spironolactone. The patient presented the following health conditions:
  • Hyponatraemia
  • Weight Increased
. Spironolactone dosage: Unk. Additional drugs used at the same time:
  • Lasix (Unk)
  • Zyvox (1200 Mg, 1x/day)
  • Trichlormethiazide (Unk)
  • Zyvox (1200 Mg, 1x/day)
Renal Failure Acute, Hyponatraemia, Hyperkalaemia

This is a Spironolactone side effect report of a 62-year-old patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:100 Mg Am Po, start time: Apr 03, 2011), combined with: NA., and developed a serious reaction and a Hyponatraemia side effect. The patient presented with:
  • Renal Failure Acute
  • Hyponatraemia
  • Hyperkalaemia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in patients suffering from NA, resulting in Hyponatraemia.
Hyponatraemia

A 83-year-old patient (weight: NA) from DENMARK with the following symptoms: cardiac failure congestive,urinary tract infection started Spironolactone treatment (dosage: 50 Mg) on Apr 23, 2011. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Hyponatraemia
. Concurrently used drugs:
  • Trimethoprim (100 Mg;bid;po)
This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Hyponatraemia.
Subdural Haematoma, Dyspnoea, Unresponsive To Stimuli, Asthenia, Hyponatraemia, Renal Impairment

A female patient from UNITED KINGDOM was prescribed and started Spironolactone on May 30, 2011. After Spironolactone was administered, patient encountered several Spironolactone side effects: subdural haematoma, dyspnoea, unresponsive to stimuli, asthenia, hyponatraemia, renal impairment Additional patient health information: Female , weighting 113.5 lb, The consumer reported the following symptoms: . Spironolactone dosage: NA. Concurrently used drugs:
  • Gleevec (Unk)
  • Iloprost
  • Furosemide
  • Diuretics
The patient was hospitalized.
Alanine Aminotransferase Increased, Inappropriate Antidiuretic Hormone Secretion, Nausea, Decreased Appetite, Femoral Neck Fracture, Hyponatraemia, Aspartate Aminotransferase Increased

This report suggests a potential Spironolactone Hyponatraemia side effect(s) that can have serious consequences. A 89-year-old female patient from JAPAN (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: 25mg; Qd) starting NS. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Alanine Aminotransferase Increased
  • Inappropriate Antidiuretic Hormone Secretion
  • Nausea
  • Decreased Appetite
  • Femoral Neck Fracture
  • Hyponatraemia
  • Aspartate Aminotransferase Increased
Drugs used concurrently:
  • Amlodipine
  • Raloxifene Hcl
  • Paroxetine Hcl
  • Limaprost Alfadex
  • Mecobalamin
  • Etodolac
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hyponatraemia, may still occur.
Erysipelas, Hyponatraemia

An adverse event was reported by a health professional on Feb 01, 2010 by a Female taking Spironolactone (dosage: Po) was diagnosed with and. Location: SWEDEN , 67 years of age, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: erysipelas, hyponatraemia. Additional medications/treatments:
Multiple prescriptions taken:
  • Impugan
  • Movicol
  • Omeprazol
  • Enalapril Maleate
  • Simvastatin
  • Folacin
  • Alvedon
  • Betapred
The patient was hospitalized.
Anaemia, Hyperkalaemia, Hyponatraemia

This Hyponatraemia problem was reported by a pharmacist from GERMANY. A 92-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): hypertension,renal failure,pulmonary embolism.On NS a consumer started treatment with Spironolactone (dosage: 25 Mg/daily, Oral). The following drugs/medications were being taken at the same time:
  • Furosemide (furosemide) Tablet (40 Mg/daily, Oral)
  • Enoxaparin Sodium (20 Mg/daily, Subcutaneous)
  • Pantoprazole Sodium
  • Norvasc
  • Movicol (macrogol, Potassium Chloride, Sodium Bicarcbonate, Sodium Chl
  • Eunerpan (melperone Hydrochloride)
  • Atacand
  • Aricept
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Anaemia
  • Hyperkalaemia
  • Hyponatraemia
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Hyponatraemia, may become evident only after a product is in use by the general population.
Angioedema, Hyponatraemia

This is a Spironolactone side effect report of a 74-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: NA) starting Feb 09, 2006. Concurrently used drugs:
  • Lisinopril
Soon after that, the consumer experienced the following of symptoms:
  • Angioedema
  • Hyponatraemia
The patient was hospitalized. This opens a possibility that Spironolactone could cause Hyponatraemia and that some female patients may be more susceptible.
Abdominal Pain, Constipation, Hyponatraemia

This Hyponatraemia side effect was reported by a consumer or non-health professional from FRANCE on Mar 14, 2007. A female patient from FRANCE , weighting 167.6 lb, was diagnosed with and was treated with Spironolactone Tablet. Patient felt the following Spironolactone side effects: abdominal pain, constipation, hyponatraemia. Spironolactone Tablet dosage: NA.
Multiple prescriptions taken:
  • Valsartan
  • Trimetazidine
The patient was hospitalized. These side effects may potentially be related to Spironolactone Tablet.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Hyponatraemia Causes and Reviews


Table salt is a combination of two minerals - sodium and chloride Your body needs some sodium to work properly. It helps with the function of nerves and muscles. It also helps to keep the right balance of fluids in your body. Your kidneys control how much sodium is in your body. If you have too much and your kidneys can't get rid it, sodium builds up in your blood. This can lead to high blood pressure. High blood pressure can lead to other health problems.

Most people in the U.S. get more sodium in their diets than they need. A key to healthy eating is choosing foods low in sodium. The Dietary Guidelines recommend that most adults eat less than 2.3 grams per day. That equals about 1 teaspoon of table salt a day. Some people are more sensitive to the effects of salt than others and should eat less. This includes people who have high blood pressure, diabetes, or kidney problems, or are African-American or over age 50. Reading food labels can help you see how much sodium is in prepared foods.

NIH: National Heart, Lung, and Blood Institute


Spironolactone Hyponatraemia Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
Blood Creatinine Increased (48)
Fatigue (46)
Hypotension (43)
Renal Failure (41)
Dizziness (40)
Pain (37)
Bradycardia (36)
Vomiting (33)
Hyponatraemia (33)
Oedema Peripheral (31)
Atrial Fibrillation (28)
Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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